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The map label for this gene is murA [H]

Identifier: 237814068

GI number: 237814068

Start: 3704652

End: 3706001

Strand: Reverse

Name: murA [H]

Synonym: GBP346_A3853

Alternate gene names: 237814068

Gene position: 3706001-3704652 (Counterclockwise)

Preceding gene: 237814069

Following gene: 237814067

Centisome position: 90.42

GC content: 70.3

Gene sequence:

>1350_bases
GTGCAAGTCACCGTCAACGAACACGACGCCGTCGAGCGCGTCGCCACGGCAACCCCGGCCGGCAATCGGGAAGCGCACGC
GCACGGTACGGACAAGCTCGCGATCGAGGGCGGCCGGCGCCTCGCCGGCGAGATCGCCGTGTCGGGCGCGAAGAACGCCG
CGCTGCCGATCCTCTGCGCGGGCCTGCTGAGCGCCGAGCCGGTGCGCCTCGATAACGTGCCGGACCTGAAGGACGTGCGC
ACGACGCTCGCGCTGCTCGGCCAGATGGGCATGCGCGAGGAAACGGACGGCGCGCGGGTCGTGCTCGACGCGTCGCGCGT
CGACAATCCGGTCGCGCCGTACGAGCTCGTGAAGACGATGCGCGCGTCGATCCTCGTGCTCGGCCCGCTCCTCGCGCGCT
TCGGCTACGCGAAGGTGTCGCTGCCGGGCGGCTGCGCGATCGGCGCGCGGCCCGTCGACCAGCACATCAAGGGCCTGCAG
GCGATGGGCGCCGAAATCCACATCGAGCATGGCTACATCGAGGCGCGCGCGAAGCGCCTTTCGGGCGCGCGCATCGTCAC
CGACATGATCACCGTGACGGGCACCGAGAACCTGCTGATGGCGGCGACGCTCGCCGACGGCGAGACGGTGATCGAGAACG
CCGCGCGCGAGCCGGAAGTGACGGATCTCGCGCATCTGCTCGTCGCGATGGGCGCGAAGATCGACGGGATCGGCACCGAC
CGGCTCGTGATCCAGGGCGTCGAGCGCCTGCACGGCGCGACGCACGCGGTGATTCCGGACCGGATCGAGGCGGGCACGTT
CCTGTGCGCGGTCGCGGCGGCGGGCGGCGACGTGACGCTCACCGGCATGCGCGCGCACATCCTCGACGCGGTGATCGACA
AGCTGCGCGAAGCGGGCGCGACGATCGACGAAGGCGTCGACACGCTGCGCGTGCGCATGGACGGCCGGCCGAGCGCGGTC
GCGATCCGCACGTCCGAATACCCGGCGTTCCCGACCGACATGCAGGCGCAGTTCATGGCGCTGAACGCGGTGGCGCAAGG
CGTCGCGCAGGTGACCGAGACGATCTTCGAGAACCGCTTCATGCACGTGCAGGAACTGAATCGCCTCGGCGCGAACATCG
CGGTCGACGGCAACACGGCGCTCGTCACGGGTGTGCCGAAGCTCTCGGGCGCGAGCGTGATGGCGACCGATCTGCGCGCG
TCGGCGAGCCTCGTGATCGCCGGCCTTTGCGCGCAAGGCGAGACGCTCGTCGAGCGCATCTATCACTTGGACCGCGGCTA
CGACCGGATGGAAACGAAGCTGACGGCCGTCGGCGCGAACGTGCGCCGCATTTCGGGGAGCGAAGCATGA

Upstream 100 bases:

>100_bases
TATGCGGCGCTCGGCGACCGCATGAAGCAGGAAATCCACGCGCTCAGCATGAAGACGCTGACGCCCGCCGAATGGCAGAA
CGCATAAACGGAAACAGTCA

Downstream 100 bases:

>100_bases
GCGCACCGCTGACGCTGGCGTTGTCGAAAGGGCGTATCTTCGAGGAAACCGTGCCGCTTCTCGCGGCGGCGGGCGTGACG
GTCGCCGAGGACCCGGAGAC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MQVTVNEHDAVERVATATPAGNREAHAHGTDKLAIEGGRRLAGEIAVSGAKNAALPILCAGLLSAEPVRLDNVPDLKDVR
TTLALLGQMGMREETDGARVVLDASRVDNPVAPYELVKTMRASILVLGPLLARFGYAKVSLPGGCAIGARPVDQHIKGLQ
AMGAEIHIEHGYIEARAKRLSGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVTDLAHLLVAMGAKIDGIGTD
RLVIQGVERLHGATHAVIPDRIEAGTFLCAVAAAGGDVTLTGMRAHILDAVIDKLREAGATIDEGVDTLRVRMDGRPSAV
AIRTSEYPAFPTDMQAQFMALNAVAQGVAQVTETIFENRFMHVQELNRLGANIAVDGNTALVTGVPKLSGASVMATDLRA
SASLVIAGLCAQGETLVERIYHLDRGYDRMETKLTAVGANVRRISGSEA

Sequences:

>Translated_449_residues
MQVTVNEHDAVERVATATPAGNREAHAHGTDKLAIEGGRRLAGEIAVSGAKNAALPILCAGLLSAEPVRLDNVPDLKDVR
TTLALLGQMGMREETDGARVVLDASRVDNPVAPYELVKTMRASILVLGPLLARFGYAKVSLPGGCAIGARPVDQHIKGLQ
AMGAEIHIEHGYIEARAKRLSGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVTDLAHLLVAMGAKIDGIGTD
RLVIQGVERLHGATHAVIPDRIEAGTFLCAVAAAGGDVTLTGMRAHILDAVIDKLREAGATIDEGVDTLRVRMDGRPSAV
AIRTSEYPAFPTDMQAQFMALNAVAQGVAQVTETIFENRFMHVQELNRLGANIAVDGNTALVTGVPKLSGASVMATDLRA
SASLVIAGLCAQGETLVERIYHLDRGYDRMETKLTAVGANVRRISGSEA
>Mature_449_residues
MQVTVNEHDAVERVATATPAGNREAHAHGTDKLAIEGGRRLAGEIAVSGAKNAALPILCAGLLSAEPVRLDNVPDLKDVR
TTLALLGQMGMREETDGARVVLDASRVDNPVAPYELVKTMRASILVLGPLLARFGYAKVSLPGGCAIGARPVDQHIKGLQ
AMGAEIHIEHGYIEARAKRLSGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVTDLAHLLVAMGAKIDGIGTD
RLVIQGVERLHGATHAVIPDRIEAGTFLCAVAAAGGDVTLTGMRAHILDAVIDKLREAGATIDEGVDTLRVRMDGRPSAV
AIRTSEYPAFPTDMQAQFMALNAVAQGVAQVTETIFENRFMHVQELNRLGANIAVDGNTALVTGVPKLSGASVMATDLRA
SASLVIAGLCAQGETLVERIYHLDRGYDRMETKLTAVGANVRRISGSEA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=58.133971291866, Blast_Score=480, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 47312; Mature: 47312

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVTVNEHDAVERVATATPAGNREAHAHGTDKLAIEGGRRLAGEIAVSGAKNAALPILCA
CEEECCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCEEECHHEECCCCCCCHHHHHH
GLLSAEPVRLDNVPDLKDVRTTLALLGQMGMREETDGARVVLDASRVDNPVAPYELVKTM
HHHCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHCCCCCCHHHHHHHH
RASILVLGPLLARFGYAKVSLPGGCAIGARPVDQHIKGLQAMGAEIHIEHGYIEARAKRL
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHC
SGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVTDLAHLLVAMGAKIDGIGTD
CCCEEEEHEEEECCCCCEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCC
RLVIQGVERLHGATHAVIPDRIEAGTFLCAVAAAGGDVTLTGMRAHILDAVIDKLREAGA
HHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCC
TIDEGVDTLRVRMDGRPSAVAIRTSEYPAFPTDMQAQFMALNAVAQGVAQVTETIFENRF
CHHCCCEEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
MHVQELNRLGANIAVDGNTALVTGVPKLSGASVMATDLRASASLVIAGLCAQGETLVERI
HHHHHHHHCCCEEEECCCEEEEECCCCCCCCEEEEHHHHCCHHEEEEEHHCCCHHHHHHH
YHLDRGYDRMETKLTAVGANVRRISGSEA
HHHHCCHHHHHHHHHHHCCCCEECCCCCC
>Mature Secondary Structure
MQVTVNEHDAVERVATATPAGNREAHAHGTDKLAIEGGRRLAGEIAVSGAKNAALPILCA
CEEECCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCEEECHHEECCCCCCCHHHHHH
GLLSAEPVRLDNVPDLKDVRTTLALLGQMGMREETDGARVVLDASRVDNPVAPYELVKTM
HHHCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHCCCCCCHHHHHHHH
RASILVLGPLLARFGYAKVSLPGGCAIGARPVDQHIKGLQAMGAEIHIEHGYIEARAKRL
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHC
SGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVTDLAHLLVAMGAKIDGIGTD
CCCEEEEHEEEECCCCCEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCC
RLVIQGVERLHGATHAVIPDRIEAGTFLCAVAAAGGDVTLTGMRAHILDAVIDKLREAGA
HHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCC
TIDEGVDTLRVRMDGRPSAVAIRTSEYPAFPTDMQAQFMALNAVAQGVAQVTETIFENRF
CHHCCCEEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
MHVQELNRLGANIAVDGNTALVTGVPKLSGASVMATDLRASASLVIAGLCAQGETLVERI
HHHHHHHHCCCEEEECCCEEEEECCCCCCCCEEEEHHHHCCHHEEEEEHHCCCHHHHHHH
YHLDRGYDRMETKLTAVGANVRRISGSEA
HHHHCCHHHHHHHHHHHCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA