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The map label for this gene is rfaC_2 [H]

Identifier: 237813486

GI number: 237813486

Start: 3147634

End: 3148629

Strand: Reverse

Name: rfaC_2 [H]

Synonym: GBP346_A3262

Alternate gene names: 237813486

Gene position: 3148629-3147634 (Counterclockwise)

Preceding gene: 237813487

Following gene: 237813485

Centisome position: 76.82

GC content: 71.69

Gene sequence:

>996_bases
GTGCAAAAAATTCTGATCGTGCGCGTGTCGTCGCTCGGCGATGTCGTGCATAACATGCCGGTGATCGCCGATATCCGCCG
GCGTCACCCCGATGCGCAGATCGACTGGCTCGTCGAGGAAGGCTTCGCCGATCTCGTGCGGCTCGTCGACGGTGTGCGCG
ACGTGCTGCCGTTCTCGCTGCGGCGCTGGCGCAAGCGCTTGAGCGCGTCGCAAACGTGGCGCGAGATCCGCGCGTTCCGG
CGGCGCCTCGCCGAGGAGCGCTACGACCTCGTGATCGACTGCCAGGGGCTCATCAAGACCGCGTGGGTCGCGAGCTGGGC
GCGCGGGCCGCTTGTCGGCCTCGGCAACCGCACCGACGGCGCCGGCTACGAGTGGCCGGTGCGCTTCTTCTACGACAGGC
GGGTGCCGATCGCGCCGCGCACGCACGTTGTCGAGCGCTCGCGGCAGCTCGTCGCGGCGGCGCTGGGAGACCCCGCGCCG
GCGCCCGGCGAGCCGATCGATTTCGGCCTCGACACGCATGGCGCGGCGCGCGCGCTCGCGGCGCTCGATTTGAATCTGCC
GGTGCCCTACGTGGTATTCGTGCACGCGACCTCGCGCGCCGACAAGCAGTGGCCCGACGAAGCGTGGACCGGCCTCGGCG
AGGCGCTCGTGCGGCGCGGCGCGTCGCTCGTGCTGCCGTGGGGCAGCGACGCCGAGCGCGCGACGAGCGAGCGCCTCGCG
AAGGCGTTCGGCGCGGCGGCGATCGTGCCGCCGAAGCTGTCGCTGCCCGCGGTCGTCGGCCTCGTCGACGGCGCGGCGGC
GACGGTCGGCGTCGATACCGGCCTCGTCCACATCGCGGCGGCGCTCAAGCGTCCGACCGTCGAACTGTACAATTTCGCGA
CAGCCTGGCGCACGGGCGGCTACTGGTCGCCCAACGTCGTCAATCTCGGCACCGCCGGCGCGCCGCCGTCCCTTTCGCAG
GCGAAGGACGCACTCGCGTCGTTCGGCCTCTTGTAA

Upstream 100 bases:

>100_bases
GCATGCGTGCGTTCGCCGCTTTTTGTCTGTGTCGGCCGCCCGGCGCGATAAAATCCGTCCTTTCGGTCTGTGCCGGCCAC
CGCCGGCCCTTTTTTTCAGC

Downstream 100 bases:

>100_bases
TCCCGACAGGCGATCATGAGCGAATCCCAGATCATCGAAATTGCGTCCGCCGACTGGAGCGGACAACAGCTGTCCGTGCC
GCGCGAGCAACTGCTCGCGG

Product: lipopolysaccharide heptosyltransferase I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MQKILIVRVSSLGDVVHNMPVIADIRRRHPDAQIDWLVEEGFADLVRLVDGVRDVLPFSLRRWRKRLSASQTWREIRAFR
RRLAEERYDLVIDCQGLIKTAWVASWARGPLVGLGNRTDGAGYEWPVRFFYDRRVPIAPRTHVVERSRQLVAAALGDPAP
APGEPIDFGLDTHGAARALAALDLNLPVPYVVFVHATSRADKQWPDEAWTGLGEALVRRGASLVLPWGSDAERATSERLA
KAFGAAAIVPPKLSLPAVVGLVDGAAATVGVDTGLVHIAAALKRPTVELYNFATAWRTGGYWSPNVVNLGTAGAPPSLSQ
AKDALASFGLL

Sequences:

>Translated_331_residues
MQKILIVRVSSLGDVVHNMPVIADIRRRHPDAQIDWLVEEGFADLVRLVDGVRDVLPFSLRRWRKRLSASQTWREIRAFR
RRLAEERYDLVIDCQGLIKTAWVASWARGPLVGLGNRTDGAGYEWPVRFFYDRRVPIAPRTHVVERSRQLVAAALGDPAP
APGEPIDFGLDTHGAARALAALDLNLPVPYVVFVHATSRADKQWPDEAWTGLGEALVRRGASLVLPWGSDAERATSERLA
KAFGAAAIVPPKLSLPAVVGLVDGAAATVGVDTGLVHIAAALKRPTVELYNFATAWRTGGYWSPNVVNLGTAGAPPSLSQ
AKDALASFGLL
>Mature_331_residues
MQKILIVRVSSLGDVVHNMPVIADIRRRHPDAQIDWLVEEGFADLVRLVDGVRDVLPFSLRRWRKRLSASQTWREIRAFR
RRLAEERYDLVIDCQGLIKTAWVASWARGPLVGLGNRTDGAGYEWPVRFFYDRRVPIAPRTHVVERSRQLVAAALGDPAP
APGEPIDFGLDTHGAARALAALDLNLPVPYVVFVHATSRADKQWPDEAWTGLGEALVRRGASLVLPWGSDAERATSERLA
KAFGAAAIVPPKLSLPAVVGLVDGAAATVGVDTGLVHIAAALKRPTVELYNFATAWRTGGYWSPNVVNLGTAGAPPSLSQ
AKDALASFGLL

Specific function: Heptose transfer to the lipopolysaccharide core. It transfers the innnermost heptose to [4'-P](3-deoxy-D-manno- octulosonic acid)2-IVA [H]

COG id: COG0859

COG function: function code M; ADP-heptose:LPS heptosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 9 family [H]

Homologues:

Organism=Escherichia coli, GI1790051, Length=330, Percent_Identity=37.2727272727273, Blast_Score=194, Evalue=9e-51,
Organism=Escherichia coli, GI1790062, Length=312, Percent_Identity=25.3205128205128, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002201
- InterPro:   IPR011908 [H]

Pfam domain/function: PF01075 Glyco_transf_9 [H]

EC number: 2.-.-.- [C]

Molecular weight: Translated: 36035; Mature: 36035

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKILIVRVSSLGDVVHNMPVIADIRRRHPDAQIDWLVEEGFADLVRLVDGVRDVLPFSL
CCCEEEEEEHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRWRKRLSASQTWREIRAFRRRLAEERYDLVIDCQGLIKTAWVASWARGPLVGLGNRTDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHCCCCEEECCCCCCC
AGYEWPVRFFYDRRVPIAPRTHVVERSRQLVAAALGDPAPAPGEPIDFGLDTHGAARALA
CCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
ALDLNLPVPYVVFVHATSRADKQWPDEAWTGLGEALVRRGASLVLPWGSDAERATSERLA
HEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
KAFGAAAIVPPKLSLPAVVGLVDGAAATVGVDTGLVHIAAALKRPTVELYNFATAWRTGG
HHHCCCEECCCCCCCHHHHHHHCCCHHEEECHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
YWSPNVVNLGTAGAPPSLSQAKDALASFGLL
CCCCCEEECCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQKILIVRVSSLGDVVHNMPVIADIRRRHPDAQIDWLVEEGFADLVRLVDGVRDVLPFSL
CCCEEEEEEHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRWRKRLSASQTWREIRAFRRRLAEERYDLVIDCQGLIKTAWVASWARGPLVGLGNRTDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHCCCCEEECCCCCCC
AGYEWPVRFFYDRRVPIAPRTHVVERSRQLVAAALGDPAPAPGEPIDFGLDTHGAARALA
CCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
ALDLNLPVPYVVFVHATSRADKQWPDEAWTGLGEALVRRGASLVLPWGSDAERATSERLA
HEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
KAFGAAAIVPPKLSLPAVVGLVDGAAATVGVDTGLVHIAAALKRPTVELYNFATAWRTGG
HHHCCCEECCCCCCCHHHHHHHCCCHHEEECHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
YWSPNVVNLGTAGAPPSLSQAKDALASFGLL
CCCCCEEECCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Glycosyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8478319; 8041620; 9278503; 1624462 [H]