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The map label for this gene is pgm [H]

Identifier: 237813487

GI number: 237813487

Start: 3148810

End: 3150375

Strand: Reverse

Name: pgm [H]

Synonym: GBP346_A3263

Alternate gene names: 237813487

Gene position: 3150375-3148810 (Counterclockwise)

Preceding gene: 237813493

Following gene: 237813486

Centisome position: 76.87

GC content: 67.11

Gene sequence:

>1566_bases
ATGGGCGCGATCGGCGTAGCTGAAACCAGCGATTATAAGTTGGATCGGATTCGCTTCCGGCATCGGCGGTGCGTTGCGTT
GCCCCCCTCGCCGGTCGGTTCGGGCGAGGATTTTTTACGCATTCGCGTTGAGGCGGCCAAATTTTTTATGGACGACACAG
AGAGTGAATCGATGATCTCCCAATCCATCTTCAAGGCATACGATATTCGGGGCGTGATCGGCAAGACGCTCGACGCCGAC
GTCGCGCGCTCGATCGGCCGCGCATTCGGCAGCGAAGTGCGCGCGCAGGGCGGCGACGCGGTCGTCGTCGCGCGCGACGG
CCGGCTCTCGGGGCCCGATCTCGTCGGCGCGCTCGCGGACGGGCTGCGCGCGGCGGGCGTCGATGTCGTCGACGTCGGCA
TGGTGCCGACGCCCGTCGGCTACTTCGCGGCGAGCGTGCCGCTCGCGCTGTCGGGCGGCGAGCGCCGCGTCGATTCGTGC
ATCGTCGTCACGGGCAGCCACAATCCGCCCGACTACAACGGTTTCAAGATGGTCCTGCGCGGCGCCGCGATTTACGGCGA
CCAGATCCAGGGCCTGTACAAGCGCATCGTCGACGCGCGTTTCGAGACCGGCAACGGTTCGTATGAGCGATACGATGTCG
CCGATCAATACGTCGAGCGCATCGTCGGCGACATCAGGCTCGCGCGGCCGCTGAAGCTCGTCGTCGATGCGGGCAACGGC
GTCGCGGGCCCGCTCGCGACGCGCCTGTTCAAGGCGCTCGGCTGCGAACTCGTCGAGCTCTTCACCGACATCGACGGCAA
CTTCCCGAACCACCACCCGGACCCGGCGCACCCGGAGAACCTGCAGGACGTGATCGCGAAGCTGAAGACGACCGATGCCG
AGATCGGCTTCGCGTTCGACGGCGACGGCGACCGCCTCGGCGTCGTCACGAAGGACGGCCAGATCATCTATCCGGACCGC
CAGCTGATGCTGTTCGCCGAGGAAGTGCTGTCGCGCAACCCGGGCGCGCAGATCATCTACGACGTGAAGTGCACGCGCAA
TCTCGCGCAGTGGGTGCGCGAGAAGGGCGGCGAGCCGCTGATGTGGAAGACGGGCCACTCGCTCGTGAAGGCGAAGCTGC
GCGAGACGGGCGCGCCGCTCGCGGGCGAGATGAGCGGCCACGTGTTCTTCAAGGATCGCTGGTACGGCTTCGACGACGGC
CTCTACACGGGCGCGCGCCTGCTCGAGATCCTCGCGCGCGCGGCCGATCCGAGCGCGCTGCTCAACGGCTTGCCGAACGC
GGTGTCGACGCCCGAGCTGCAACTGAAGCTCGACGAAGGCGAGAACGTGAAGCTGATCGACAAGCTGCGCGCCGACGCGA
AGTTCGACGGCGCGGACGAGGTCGTGACGATCGACGGTCTGCGCGTCGAGTATCCGGACGGCTTCGGTCTCGCGCGTTCG
TCGAACACGACGCCCGTGGTCGTGCTGCGCTTCGAGGCGAGCTCCGACGCGGCGCTCGCGCGGATCCAGGACGATTTCCG
GCGCGCGCTGAAGGCGGCGAAGCCGGACGCGAACCTGCCGTTCTGA

Upstream 100 bases:

>100_bases
TGGATTTCAGCATGGCGCGCGGCGCGGCAACGTGCGCGAGATGACCTGGCCGGCCGACCGCGGGAGCGGTTTTGCTGCGA
TGAAGCATTCAGGCATTAAA

Downstream 100 bases:

>100_bases
GCTTGACGGCGGCGCGGCGCGCGCCGGGCGCGGCGTGCCCGAGCTTGCGCTGACGCAAGCCTTGTCCAAAAAGCGGCGAC
GCATGCGTGCGTTCGCCGCT

Product: phosphomannomutase/phosphoglucomutase (PMM /PGM)

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 521; Mature: 520

Protein sequence:

>521_residues
MGAIGVAETSDYKLDRIRFRHRRCVALPPSPVGSGEDFLRIRVEAAKFFMDDTESESMISQSIFKAYDIRGVIGKTLDAD
VARSIGRAFGSEVRAQGGDAVVVARDGRLSGPDLVGALADGLRAAGVDVVDVGMVPTPVGYFAASVPLALSGGERRVDSC
IVVTGSHNPPDYNGFKMVLRGAAIYGDQIQGLYKRIVDARFETGNGSYERYDVADQYVERIVGDIRLARPLKLVVDAGNG
VAGPLATRLFKALGCELVELFTDIDGNFPNHHPDPAHPENLQDVIAKLKTTDAEIGFAFDGDGDRLGVVTKDGQIIYPDR
QLMLFAEEVLSRNPGAQIIYDVKCTRNLAQWVREKGGEPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDG
LYTGARLLEILARAADPSALLNGLPNAVSTPELQLKLDEGENVKLIDKLRADAKFDGADEVVTIDGLRVEYPDGFGLARS
SNTTPVVVLRFEASSDAALARIQDDFRRALKAAKPDANLPF

Sequences:

>Translated_521_residues
MGAIGVAETSDYKLDRIRFRHRRCVALPPSPVGSGEDFLRIRVEAAKFFMDDTESESMISQSIFKAYDIRGVIGKTLDAD
VARSIGRAFGSEVRAQGGDAVVVARDGRLSGPDLVGALADGLRAAGVDVVDVGMVPTPVGYFAASVPLALSGGERRVDSC
IVVTGSHNPPDYNGFKMVLRGAAIYGDQIQGLYKRIVDARFETGNGSYERYDVADQYVERIVGDIRLARPLKLVVDAGNG
VAGPLATRLFKALGCELVELFTDIDGNFPNHHPDPAHPENLQDVIAKLKTTDAEIGFAFDGDGDRLGVVTKDGQIIYPDR
QLMLFAEEVLSRNPGAQIIYDVKCTRNLAQWVREKGGEPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDG
LYTGARLLEILARAADPSALLNGLPNAVSTPELQLKLDEGENVKLIDKLRADAKFDGADEVVTIDGLRVEYPDGFGLARS
SNTTPVVVLRFEASSDAALARIQDDFRRALKAAKPDANLPF
>Mature_520_residues
GAIGVAETSDYKLDRIRFRHRRCVALPPSPVGSGEDFLRIRVEAAKFFMDDTESESMISQSIFKAYDIRGVIGKTLDADV
ARSIGRAFGSEVRAQGGDAVVVARDGRLSGPDLVGALADGLRAAGVDVVDVGMVPTPVGYFAASVPLALSGGERRVDSCI
VVTGSHNPPDYNGFKMVLRGAAIYGDQIQGLYKRIVDARFETGNGSYERYDVADQYVERIVGDIRLARPLKLVVDAGNGV
AGPLATRLFKALGCELVELFTDIDGNFPNHHPDPAHPENLQDVIAKLKTTDAEIGFAFDGDGDRLGVVTKDGQIIYPDRQ
LMLFAEEVLSRNPGAQIIYDVKCTRNLAQWVREKGGEPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGL
YTGARLLEILARAADPSALLNGLPNAVSTPELQLKLDEGENVKLIDKLRADAKFDGADEVVTIDGLRVEYPDGFGLARSS
NTTPVVVLRFEASSDAALARIQDDFRRALKAAKPDANLPF

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=457, Percent_Identity=37.199124726477, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1789566, Length=482, Percent_Identity=24.4813278008299, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 56484; Mature: 56353

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAIGVAETSDYKLDRIRFRHRRCVALPPSPVGSGEDFLRIRVEAAKFFMDDTESESMIS
CCCCCCCCCCCCHHHHHHHHCCEEEECCCCCCCCCCCEEEEEEEHHHHHHCCCCHHHHHH
QSIFKAYDIRGVIGKTLDADVARSIGRAFGSEVRAQGGDAVVVARDGRLSGPDLVGALAD
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHH
GLRAAGVDVVDVGMVPTPVGYFAASVPLALSGGERRVDSCIVVTGSHNPPDYNGFKMVLR
HHHHCCCCEEECCCCCCCHHHHHHCCCEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHH
GAAIYGDQIQGLYKRIVDARFETGNGSYERYDVADQYVERIVGDIRLARPLKLVVDAGNG
HHHHCCHHHHHHHHHHHHCEEECCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
VAGPLATRLFKALGCELVELFTDIDGNFPNHHPDPAHPENLQDVIAKLKTTDAEIGFAFD
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEC
GDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRNLAQWVREKGGEPL
CCCCEEEEEECCCEEECCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCCCE
MWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILARAADPSAL
EECCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHH
LNGLPNAVSTPELQLKLDEGENVKLIDKLRADAKFDGADEVVTIDGLRVEYPDGFGLARS
HHCCCCCCCCCCEEEEECCCCCEEHHHHHHCCCCCCCCCCEEEECCEEEECCCCCCCCCC
SNTTPVVVLRFEASSDAALARIQDDFRRALKAAKPDANLPF
CCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GAIGVAETSDYKLDRIRFRHRRCVALPPSPVGSGEDFLRIRVEAAKFFMDDTESESMIS
CCCCCCCCCCCHHHHHHHHCCEEEECCCCCCCCCCCEEEEEEEHHHHHHCCCCHHHHHH
QSIFKAYDIRGVIGKTLDADVARSIGRAFGSEVRAQGGDAVVVARDGRLSGPDLVGALAD
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHH
GLRAAGVDVVDVGMVPTPVGYFAASVPLALSGGERRVDSCIVVTGSHNPPDYNGFKMVLR
HHHHCCCCEEECCCCCCCHHHHHHCCCEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHH
GAAIYGDQIQGLYKRIVDARFETGNGSYERYDVADQYVERIVGDIRLARPLKLVVDAGNG
HHHHCCHHHHHHHHHHHHCEEECCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
VAGPLATRLFKALGCELVELFTDIDGNFPNHHPDPAHPENLQDVIAKLKTTDAEIGFAFD
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEC
GDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRNLAQWVREKGGEPL
CCCCEEEEEECCCEEECCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCCCE
MWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILARAADPSAL
EECCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHH
LNGLPNAVSTPELQLKLDEGENVKLIDKLRADAKFDGADEVVTIDGLRVEYPDGFGLARS
HHCCCCCCCCCCEEEEECCCCCEEHHHHHHCCCCCCCCCCEEEECCEEEECCCCCCCCCC
SNTTPVVVLRFEASSDAALARIQDDFRRALKAAKPDANLPF
CCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157643; 8188595 [H]