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The map label for this gene is gph_1 [C]

Identifier: 237813305

GI number: 237813305

Start: 2988459

End: 2989184

Strand: Direct

Name: gph_1 [C]

Synonym: GBP346_A3072

Alternate gene names: 237813305

Gene position: 2988459-2989184 (Clockwise)

Preceding gene: 237813304

Following gene: 237813306

Centisome position: 72.91

GC content: 72.87

Gene sequence:

>726_bases
ATGAGCCCTTCGTCGCCCTCCTTCGCCGCCCCGCTGTCCGACGCGCCGCGCCTCGACGCATGCGAGGCCGTGCTGTTCGA
TCTCGACGGCACGCTCGCCGACACCGCGCCCGATCTCGCCGCCGCGGTCAACAAGATGCAGCGCTCGCGCGGCATCGCAC
AAACGCCGCTCGACGCGCTGCGCCCGCTCGCGTCGGCGGGCGCGCGCGGCCTGATCGGCGGCGCGTTCGGCATCGCGCCC
GCGGACGCCGAATTCGACGCGCTGCGCGACGAATTCCTCGCGAACTACGCGACGGATCTGTGCGTGCACACGACGCTCTT
TCCAGGCATCGGCGCGCTGCTCGACGACCTCGACGCGCGCGGCGTGCGCTGGGGCATCGTGACCAACAAGGCTGCGCGGT
TCACCGATCCGCTCGTTGCGCTGCTCGGCCTCGCGGCGCGCGCGGCGTGCGTGGTCAGCGGCGACACGGCATCGCACCCG
AAGCCGCATCCGGCGCCGCTGCTGTACGCGGCCGACCGCCTCTCGCTCGCCCCCGAGCGGATCGTGTACGTCGGCGACGA
CCTTCGCGACATCCAGGCGGGCAGCGCGGCCGGCATGCCGACGGTCGCCGCCGCGTACGGCTATTGCGGCGACGGCGCCG
CCCCCGCCGACTGGCGTGCGCAGCATCTCGTCGAGACGACGGACGACCTGCAGCGGCTGCTGCGCGTGTTGCGCTATAAT
GCTTGA

Upstream 100 bases:

>100_bases
CCGCTCGCGAAGCGCTTCGCGCTGTCGAACGACACCGACGTCAACTATCTCGTCGCGTGCCGCCGCGGCGCCTGACCCGC
CACTCGCTCCGATCGCATTC

Downstream 100 bases:

>100_bases
TCCGCTGGGGGCGACCTGGTTTCGACAGGGGTTGTGAAGCGGCTAGGGCATGTCGAGGACCCGTCACCTCGTTAATCAAT
GGGAAAAACGTAACTGCAAA

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MSPSSPSFAAPLSDAPRLDACEAVLFDLDGTLADTAPDLAAAVNKMQRSRGIAQTPLDALRPLASAGARGLIGGAFGIAP
ADAEFDALRDEFLANYATDLCVHTTLFPGIGALLDDLDARGVRWGIVTNKAARFTDPLVALLGLAARAACVVSGDTASHP
KPHPAPLLYAADRLSLAPERIVYVGDDLRDIQAGSAAGMPTVAAAYGYCGDGAAPADWRAQHLVETTDDLQRLLRVLRYN
A

Sequences:

>Translated_241_residues
MSPSSPSFAAPLSDAPRLDACEAVLFDLDGTLADTAPDLAAAVNKMQRSRGIAQTPLDALRPLASAGARGLIGGAFGIAP
ADAEFDALRDEFLANYATDLCVHTTLFPGIGALLDDLDARGVRWGIVTNKAARFTDPLVALLGLAARAACVVSGDTASHP
KPHPAPLLYAADRLSLAPERIVYVGDDLRDIQAGSAAGMPTVAAAYGYCGDGAAPADWRAQHLVETTDDLQRLLRVLRYN
A
>Mature_240_residues
SPSSPSFAAPLSDAPRLDACEAVLFDLDGTLADTAPDLAAAVNKMQRSRGIAQTPLDALRPLASAGARGLIGGAFGIAPA
DAEFDALRDEFLANYATDLCVHTTLFPGIGALLDDLDARGVRWGIVTNKAARFTDPLVALLGLAARAACVVSGDTASHPK
PHPAPLLYAADRLSLAPERIVYVGDDLRDIQAGSAAGMPTVAAAYGYCGDGAAPADWRAQHLVETTDDLQRLLRVLRYNA

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=212, Percent_Identity=34.9056603773585, Blast_Score=111, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 25135; Mature: 25003

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPSSPSFAAPLSDAPRLDACEAVLFDLDGTLADTAPDLAAAVNKMQRSRGIAQTPLDAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCCCCHHHH
RPLASAGARGLIGGAFGIAPADAEFDALRDEFLANYATDLCVHTTLFPGIGALLDDLDAR
HHHHHCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVRWGIVTNKAARFTDPLVALLGLAARAACVVSGDTASHPKPHPAPLLYAADRLSLAPER
CEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEHHHHHCCCCE
IVYVGDDLRDIQAGSAAGMPTVAAAYGYCGDGAAPADWRAQHLVETTDDLQRLLRVLRYN
EEEECCCHHHHCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
A
C
>Mature Secondary Structure 
SPSSPSFAAPLSDAPRLDACEAVLFDLDGTLADTAPDLAAAVNKMQRSRGIAQTPLDAL
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCCCCHHHH
RPLASAGARGLIGGAFGIAPADAEFDALRDEFLANYATDLCVHTTLFPGIGALLDDLDAR
HHHHHCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVRWGIVTNKAARFTDPLVALLGLAARAACVVSGDTASHPKPHPAPLLYAADRLSLAPER
CEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEHHHHHCCCCE
IVYVGDDLRDIQAGSAAGMPTVAAAYGYCGDGAAPADWRAQHLVETTDDLQRLLRVLRYN
EEEECCCHHHHCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA