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The map label for this gene is ubiG [H]

Identifier: 237813304

GI number: 237813304

Start: 2987690

End: 2988433

Strand: Direct

Name: ubiG [H]

Synonym: GBP346_A3071

Alternate gene names: 237813304

Gene position: 2987690-2988433 (Clockwise)

Preceding gene: 237813303

Following gene: 237813305

Centisome position: 72.9

GC content: 66.53

Gene sequence:

>744_bases
TTGGCGGGCGCGCCGCCGCCCTCTTTCCCGCATCCGCTTGCCGACATGACGAACGCCGATCCGCACGAACTCCAGAAATT
CAGCGACCTCGCTCACAAATGGTGGGATCCGAACGCCGAATTCAAGCCTCTGCACGACCTCAATCCGGTTCGCCTGAGCT
GGATCGACGCGCACGCGCATTTGCCCGGCAAGCGCGTCGTCGACATCGGCTGCGGCGGCGGCATCCTGTCTGAATCGATG
GCGTCGCTCGGCGCGCAGGTCAAGGGCATCGACCTGGCGACGGAAGCGCTCGGCGTCGCCGATCTGCACAGCCTCGAAAG
CGGCGTGAGCGTCGATTACGAGGCGATCGCGGCCGAAGCGCTCGCCGCGCGCGAACCGGGCGCGTACGATGTCGTCACGT
GCATGGAGATGCTCGAGCACGTGCCGTCGCCCGCGAACATCGTCGCCGCGTGCGCGACGCTCGTGAAGCCGGGCGGCTGG
GTGTTCTTCTCGACGCTGAACCGCAACCTGAAGTCGTACCTGCTCGCCGTGATCGGCGCCGAATACATCGCGCAAATGCT
GCCGAAGGGCACGCACGACTACGCGCGCTTCATCCGCCCGTCCGAGCTCGCGCGCTTCGTGCGCGAAGCGGGCCTGCAGA
TGGTCGAGATCAAGGGCATCGCCTATCATCCGCTCGCGAAGCGCTTCGCGCTGTCGAACGACACCGACGTCAACTATCTC
GTCGCGTGCCGCCGCGGCGCCTGA

Upstream 100 bases:

>100_bases
TCAAAAGCCCCGCTCCAGCGGGGCTTTTTCATTGATGCGGCCCGCCTTACCCGCGGCCGCGTTCCTGGCGACCTCGCCCG
CGCGCTTATATACTCGTGGC

Downstream 100 bases:

>100_bases
CCCGCCACTCGCTCCGATCGCATTCATGAGCCCTTCGTCGCCCTCCTTCGCCGCCCCGCTGTCCGACGCGCCGCGCCTCG
ACGCATGCGAGGCCGTGCTG

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MAGAPPPSFPHPLADMTNADPHELQKFSDLAHKWWDPNAEFKPLHDLNPVRLSWIDAHAHLPGKRVVDIGCGGGILSESM
ASLGAQVKGIDLATEALGVADLHSLESGVSVDYEAIAAEALAAREPGAYDVVTCMEMLEHVPSPANIVAACATLVKPGGW
VFFSTLNRNLKSYLLAVIGAEYIAQMLPKGTHDYARFIRPSELARFVREAGLQMVEIKGIAYHPLAKRFALSNDTDVNYL
VACRRGA

Sequences:

>Translated_247_residues
MAGAPPPSFPHPLADMTNADPHELQKFSDLAHKWWDPNAEFKPLHDLNPVRLSWIDAHAHLPGKRVVDIGCGGGILSESM
ASLGAQVKGIDLATEALGVADLHSLESGVSVDYEAIAAEALAAREPGAYDVVTCMEMLEHVPSPANIVAACATLVKPGGW
VFFSTLNRNLKSYLLAVIGAEYIAQMLPKGTHDYARFIRPSELARFVREAGLQMVEIKGIAYHPLAKRFALSNDTDVNYL
VACRRGA
>Mature_246_residues
AGAPPPSFPHPLADMTNADPHELQKFSDLAHKWWDPNAEFKPLHDLNPVRLSWIDAHAHLPGKRVVDIGCGGGILSESMA
SLGAQVKGIDLATEALGVADLHSLESGVSVDYEAIAAEALAAREPGAYDVVTCMEMLEHVPSPANIVAACATLVKPGGWV
FFSTLNRNLKSYLLAVIGAEYIAQMLPKGTHDYARFIRPSELARFVREAGLQMVEIKGIAYHPLAKRFALSNDTDVNYLV
ACRRGA

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=251, Percent_Identity=33.0677290836653, Blast_Score=160, Evalue=1e-39,
Organism=Escherichia coli, GI1788564, Length=225, Percent_Identity=56.4444444444444, Blast_Score=261, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI115533050, Length=234, Percent_Identity=32.9059829059829, Blast_Score=131, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6324476, Length=282, Percent_Identity=30.1418439716312, Blast_Score=128, Evalue=9e-31,
Organism=Drosophila melanogaster, GI281365311, Length=238, Percent_Identity=30.2521008403361, Blast_Score=127, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24585589, Length=234, Percent_Identity=29.9145299145299, Blast_Score=119, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 26693; Mature: 26562

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGAPPPSFPHPLADMTNADPHELQKFSDLAHKWWDPNAEFKPLHDLNPVRLSWIDAHAH
CCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCC
LPGKRVVDIGCGGGILSESMASLGAQVKGIDLATEALGVADLHSLESGVSVDYEAIAAEA
CCCCEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LAAREPGAYDVVTCMEMLEHVPSPANIVAACATLVKPGGWVFFSTLNRNLKSYLLAVIGA
HHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHH
EYIAQMLPKGTHDYARFIRPSELARFVREAGLQMVEIKGIAYHPLAKRFALSNDTDVNYL
HHHHHHCCCCCHHHHHHCCHHHHHHHHHHCCCEEEEECCCEECHHHHHHHCCCCCCCEEE
VACRRGA
EEECCCC
>Mature Secondary Structure 
AGAPPPSFPHPLADMTNADPHELQKFSDLAHKWWDPNAEFKPLHDLNPVRLSWIDAHAH
CCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCC
LPGKRVVDIGCGGGILSESMASLGAQVKGIDLATEALGVADLHSLESGVSVDYEAIAAEA
CCCCEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LAAREPGAYDVVTCMEMLEHVPSPANIVAACATLVKPGGWVFFSTLNRNLKSYLLAVIGA
HHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHH
EYIAQMLPKGTHDYARFIRPSELARFVREAGLQMVEIKGIAYHPLAKRFALSNDTDVNYL
HHHHHHCCCCCHHHHHHCCHHHHHHHHHHCCCEEEEECCCEECHHHHHHHCCCCCCCEEE
VACRRGA
EEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA