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The map label for this gene is prmB [C]

Identifier: 237812823

GI number: 237812823

Start: 2513748

End: 2514671

Strand: Direct

Name: prmB [C]

Synonym: GBP346_A2577

Alternate gene names: 237812823

Gene position: 2513748-2514671 (Clockwise)

Preceding gene: 237812822

Following gene: 237812824

Centisome position: 61.33

GC content: 69.26

Gene sequence:

>924_bases
ATGACGACATCCCCCACCCCGTTCAAGACTGTCCGCGACCTCGTGCGCCACGCGGTGTCGCGCTTCTCGCAGGCGAAGCT
CGCGTTCGGCCACGGCTCGGACAACGCGTTCGACGAAGCGGTCTACCTCGTGCTGCACACGCTGCACCTGCCGCTCGACA
CGCTCGAGCCGTTCCTCGACGCGCGCCTCGCGCCCGACGAAATCGACGCGGTGCTCGCCGTGATCGAACGCCGCGCGACC
GAGCGCGTGCCCGCCGCGTATCTCACGCGCGAAGCGTGGATGCACGGCCATCGCTTCTACGTCGACGAGCGCGTGATCGT
TCCGCGCTCGTTCATCGGCGAGCTGCTCGACGACGGCCTGCAACCGTACGTCGAGGATCCCGAGCTCGTCGGCTCGGTGC
TCGAGCTGTGCACGGGCTCCGGCTGCCTCGCGATCCTCGCCGCGCTCGCGTTCCCGAATGCGAGCGTCGACGCGGTCGAC
CTGTCGGCCGACGCGCTCGCCGTCGCGAAGATCAACCGCGACAATTACGGGCTCGACGAGCAGATCGCGCTCTACCACGG
CGATCTGTACGCGCCGCTGCCGCAATTCAAGTGGATCGATCCCGCGCAGCGCTACGACGTGATCATCGCGAACCCGCCTT
ACGTGAACGCGGGTTCGATGGCCGAGCTGCCGGCCGAATACCGGCACGAGCCGGAAATGGCGCTCGCGGGCGGCGCGGAC
GGCATGGACATCGTGCGACGCATCATCGGCGAAGCGCGCCGCTGGCTGCAGGACGACGGCGTGCTCGTCGTCGAGATCGG
CAACGAACGCGCGAACGTCGAGGCGGCGTTCGGCGGCCTCGAGCTCGTCTGGCTGCCGACGAGCGCGGGCGACGGCAGCG
TGTTCCTGATCCACGCGAGCGAGCTGCCCGCCGTCGCCGGCTGA

Upstream 100 bases:

>100_bases
CACAAGATCGACGAGCACATCGACGTGCGCTTCGTCGACCCGCTGAAGAACGTGTACCGCCGCGTGCTCGAACAACTGAT
CGCCTGACGAAGGCCGCCCG

Downstream 100 bases:

>100_bases
CGCTTGCGCGGCTCCCGGGCGAGCCGGCATGGTCGTGGCCGCGATGTCCGCGACCGGCATGTCCGCAACCGGCACGTCCG
CGACCGGCACGTCCGCAACC

Product: N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MTTSPTPFKTVRDLVRHAVSRFSQAKLAFGHGSDNAFDEAVYLVLHTLHLPLDTLEPFLDARLAPDEIDAVLAVIERRAT
ERVPAAYLTREAWMHGHRFYVDERVIVPRSFIGELLDDGLQPYVEDPELVGSVLELCTGSGCLAILAALAFPNASVDAVD
LSADALAVAKINRDNYGLDEQIALYHGDLYAPLPQFKWIDPAQRYDVIIANPPYVNAGSMAELPAEYRHEPEMALAGGAD
GMDIVRRIIGEARRWLQDDGVLVVEIGNERANVEAAFGGLELVWLPTSAGDGSVFLIHASELPAVAG

Sequences:

>Translated_307_residues
MTTSPTPFKTVRDLVRHAVSRFSQAKLAFGHGSDNAFDEAVYLVLHTLHLPLDTLEPFLDARLAPDEIDAVLAVIERRAT
ERVPAAYLTREAWMHGHRFYVDERVIVPRSFIGELLDDGLQPYVEDPELVGSVLELCTGSGCLAILAALAFPNASVDAVD
LSADALAVAKINRDNYGLDEQIALYHGDLYAPLPQFKWIDPAQRYDVIIANPPYVNAGSMAELPAEYRHEPEMALAGGAD
GMDIVRRIIGEARRWLQDDGVLVVEIGNERANVEAAFGGLELVWLPTSAGDGSVFLIHASELPAVAG
>Mature_306_residues
TTSPTPFKTVRDLVRHAVSRFSQAKLAFGHGSDNAFDEAVYLVLHTLHLPLDTLEPFLDARLAPDEIDAVLAVIERRATE
RVPAAYLTREAWMHGHRFYVDERVIVPRSFIGELLDDGLQPYVEDPELVGSVLELCTGSGCLAILAALAFPNASVDAVDL
SADALAVAKINRDNYGLDEQIALYHGDLYAPLPQFKWIDPAQRYDVIIANPPYVNAGSMAELPAEYRHEPEMALAGGADG
MDIVRRIIGEARRWLQDDGVLVVEIGNERANVEAAFGGLELVWLPTSAGDGSVFLIHASELPAVAG

Specific function: Unknown

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705409, Length=263, Percent_Identity=28.5171102661597, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI87082085, Length=298, Percent_Identity=46.3087248322148, Blast_Score=271, Evalue=3e-74,
Organism=Escherichia coli, GI1787463, Length=223, Percent_Identity=27.3542600896861, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR017127
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 33480; Mature: 33349

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSPTPFKTVRDLVRHAVSRFSQAKLAFGHGSDNAFDEAVYLVLHTLHLPLDTLEPFLD
CCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
ARLAPDEIDAVLAVIERRATERVPAAYLTREAWMHGHRFYVDERVIVPRSFIGELLDDGL
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCEEECCHHHHHHHHHCCC
QPYVEDPELVGSVLELCTGSGCLAILAALAFPNASVDAVDLSADALAVAKINRDNYGLDE
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEECCCCEEEEEEECCCCCCCCC
QIALYHGDLYAPLPQFKWIDPAQRYDVIIANPPYVNAGSMAELPAEYRHEPEMALAGGAD
EEEEEECCCCCCCCCCCCCCCHHHCEEEECCCCCCCCCCHHHCCHHHCCCCCEEEECCCC
GMDIVRRIIGEARRWLQDDGVLVVEIGNERANVEAAFGGLELVWLPTSAGDGSVFLIHAS
CHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCEEEEEEECCCCCCCEEEEECC
ELPAVAG
CCCCCCC
>Mature Secondary Structure 
TTSPTPFKTVRDLVRHAVSRFSQAKLAFGHGSDNAFDEAVYLVLHTLHLPLDTLEPFLD
CCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
ARLAPDEIDAVLAVIERRATERVPAAYLTREAWMHGHRFYVDERVIVPRSFIGELLDDGL
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCEEECCHHHHHHHHHCCC
QPYVEDPELVGSVLELCTGSGCLAILAALAFPNASVDAVDLSADALAVAKINRDNYGLDE
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEECCCCEEEEEEECCCCCCCCC
QIALYHGDLYAPLPQFKWIDPAQRYDVIIANPPYVNAGSMAELPAEYRHEPEMALAGGAD
EEEEEECCCCCCCCCCCCCCCHHHCEEEECCCCCCCCCCHHHCCHHHCCCCCEEEECCCC
GMDIVRRIIGEARRWLQDDGVLVVEIGNERANVEAAFGGLELVWLPTSAGDGSVFLIHAS
CHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCEEEEEEECCCCCCCEEEEECC
ELPAVAG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]