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The map label for this gene is dapE [H]

Identifier: 237812822

GI number: 237812822

Start: 2512595

End: 2513734

Strand: Direct

Name: dapE [H]

Synonym: GBP346_A2576

Alternate gene names: 237812822

Gene position: 2512595-2513734 (Clockwise)

Preceding gene: 237812821

Following gene: 237812823

Centisome position: 61.3

GC content: 69.12

Gene sequence:

>1140_bases
ATGTCCGCCACCCTTGCCCTCACCGAACAGTTGATCGCGCGCGCGTCCGTCACGCCCGACGATCAGCACTGCCAGCAATT
GATGATCGAGCGCCTCGCCGCCCTCGGCTTCGAGTGCGAAACGATCGCGTCGCACGGCGTGACGAACTTCTGGGCCGTCA
AGCGCGGCACGGCCGGCCGCGCAGGCAAGCTGCTCGCGTTCGCGGGCCATACCGACGTCGTGCCGACCGGCCCGCTCGAG
CAGTGGAGCTCGCCGCCGTTCGTGCCGACGCACCGCGACGGCAAGCTGTACGGCCGCGGCGCGGCCGACATGAAAACCTC
GCTCGCGGGCTTCGTCGTCGCGGCCGAGGAGTTCGTCGCCGCGCATCCGCAGCACCGCGGCTCGATCGGTTTCCTGATCA
CGAGCGACGAGGAAGGCCCGGCCACCGACGGCACCGTGAAAGTCGTCGAGGCGCTCGCCGCGCGCGGCGAGCGCCTCGAT
TACTGCATCGTCGGCGAACCGACCTCGACGGCGACGCTCGGCGACGTCGTGAAGAACGGCCGGCGCGGCTCGATGTCGGG
CGAGCTCGTCGTCAAGGGCGTGCAAGGCCATATCGCGTATCCGCATCTCGCGAAGAACCCGATCCATCTGCTCGCGCCGG
CGCTCGCCGAGCTCGCCGCCGAGCAATGGGACGAAGGCAACGAGTACTTTCCGCCGACCACCTGGCAGGTGTCGAACCTG
CGCGCGGGCACCGGCGCGACGAACGTGATTCCGGGCCACGCCGATCTGCTGTTCAACTTCCGCTTCTCGACGGCGAGCAC
GGTCGAGGGCCTGCAGGCGCGCGTGCACGCGATCCTCGACAGGCACGGGCTCGATTACACGCTGAACTGGTCGGTGAGCG
GCCTGCCGTTCCTCACGCCGCGCGGCGAGCTGTCGAACGCGCTCGACGCCGCGATCCGCGCGGAAACGGGCGTCTCGCCC
GAGCTGTCGACGACGGGCGGCACGTCCGACGGCCGCTTCATCGCGCGCATCTGCCCGCAGGTGATCGAGTTCGGCCCGCC
GAACGCGAGCATCCACAAGATCGACGAGCACATCGACGTGCGCTTCGTCGACCCGCTGAAGAACGTGTACCGCCGCGTGC
TCGAACAACTGATCGCCTGA

Upstream 100 bases:

>100_bases
GACGAGTACGCGGGGCTCTTCGCCTGAGCGCCGCGCGCCGCCGCCCCCAACCTGCTGCCGGCCGTCGCGCCGGCATTTTT
TATCGAAAGTGGTCCGAAAC

Downstream 100 bases:

>100_bases
CGAAGGCCGCCCGATGACGACATCCCCCACCCCGTTCAAGACTGTCCGCGACCTCGTGCGCCACGCGGTGTCGCGCTTCT
CGCAGGCGAAGCTCGCGTTC

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRGTAGRAGKLLAFAGHTDVVPTGPLE
QWSSPPFVPTHRDGKLYGRGAADMKTSLAGFVVAAEEFVAAHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARGERLD
YCIVGEPTSTATLGDVVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQVSNL
RAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDRHGLDYTLNWSVSGLPFLTPRGELSNALDAAIRAETGVSP
ELSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDEHIDVRFVDPLKNVYRRVLEQLIA

Sequences:

>Translated_379_residues
MSATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRGTAGRAGKLLAFAGHTDVVPTGPLE
QWSSPPFVPTHRDGKLYGRGAADMKTSLAGFVVAAEEFVAAHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARGERLD
YCIVGEPTSTATLGDVVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQVSNL
RAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDRHGLDYTLNWSVSGLPFLTPRGELSNALDAAIRAETGVSP
ELSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDEHIDVRFVDPLKNVYRRVLEQLIA
>Mature_378_residues
SATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRGTAGRAGKLLAFAGHTDVVPTGPLEQ
WSSPPFVPTHRDGKLYGRGAADMKTSLAGFVVAAEEFVAAHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARGERLDY
CIVGEPTSTATLGDVVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQVSNLR
AGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDRHGLDYTLNWSVSGLPFLTPRGELSNALDAAIRAETGVSPE
LSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDEHIDVRFVDPLKNVYRRVLEQLIA

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788816, Length=376, Percent_Identity=57.9787234042553, Blast_Score=443, Evalue=1e-126,
Organism=Escherichia coli, GI1790395, Length=387, Percent_Identity=26.0981912144703, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 40637; Mature: 40506

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRGTAGR
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCCC
AGKLLAFAGHTDVVPTGPLEQWSSPPFVPTHRDGKLYGRGAADMKTSLAGFVVAAEEFVA
CCCEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHH
AHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARGERLDYCIVGEPTSTATLGDVVKNG
CCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCC
RRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQVSNL
CCCCCCCCEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCE
RAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDRHGLDYTLNWSVSGLPFLTP
ECCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEECC
RGELSNALDAAIRAETGVSPELSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDEHIDV
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCE
RFVDPLKNVYRRVLEQLIA
EEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRGTAGR
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCCC
AGKLLAFAGHTDVVPTGPLEQWSSPPFVPTHRDGKLYGRGAADMKTSLAGFVVAAEEFVA
CCCEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHH
AHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARGERLDYCIVGEPTSTATLGDVVKNG
CCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCC
RRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQVSNL
CCCCCCCCEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCE
RAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDRHGLDYTLNWSVSGLPFLTP
ECCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEECC
RGELSNALDAAIRAETGVSPELSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDEHIDV
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCE
RFVDPLKNVYRRVLEQLIA
EEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA