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The map label for this gene is ynfJ [C]

Identifier: 237812483

GI number: 237812483

Start: 2192009

End: 2193748

Strand: Direct

Name: ynfJ [C]

Synonym: GBP346_A2232

Alternate gene names: 237812483

Gene position: 2192009-2193748 (Clockwise)

Preceding gene: 237812482

Following gene: 237812485

Centisome position: 53.48

GC content: 70.06

Gene sequence:

>1740_bases
GTGCTCTCGTTCCTGCTCAAGCTGCGCACCCGCGCGCAAACCCTGTTCCGGCTGTCCGACGCGCATACGATGCTCGTGTG
GTCGGTGATCGTCGGCATCGGCGGCGCGCTCGCGACGGTCGCGTTCCGCGAAGGCATCGAGCTGATCCAGCACGCGATCT
CCGGCACGAGCGGCAGCTTCACCGAGATGGCGAAGCGCCTGCCATGGCAGGTGCGGTTCTGGCTGCCCGCCGCGGGCGGC
TTTCTCGCGGGCTGCGTGCTGCTCGTCGCGCAGTGCGGCGCGCGCAAGGAAAGCAAGACCGATTACATGGAAGCCGTCGC
GCTCGGCGACGGCGTCGTGCCGGTGCGGCAGAGCCTCTGGCGCAGCGCGTCGTCGCTGCTCACGATCGGCAGCGGCGGCT
CGATCGGCCGCGAAGGCCCGATGGTGCAGCTCGCGGCGCTCGCCGCGTCGCTCGTCGGCCGCTTCGCGCACTTCGATCCG
CCGCGGCTGCGCCTGCTCGTCGCGTGCGGCGCGGCGGCGGGGATCACCTCCGCGTACAACGCGCCGATCGCGGGCGCGTT
CTTCGTCTGCGAGATCGTGCTCGGCTCGATCGCGATGGAGAGCTTCGGGCCCGTCGTCGTCGCCTCGGTCGTCGCGAACA
TCGTGATGCGCGAGTTCGCCGGCTACAAGCCGCCGTACCAGATGCCGGTGTTTCCGGCCGTCGCCGGCTGGGAAGTGCTG
TTCTTCGTCGCGCTCGGGCTGCTGTGCGGCGCGGCCGCGCCGCAGTTCCTGCGCCTGCTCGAGCTGTCCAAGGCGCAGTT
CAAGCGCCTGCCCGTCCCGCTGCCCGTGCGGCTCGCCGCGGGCGGGCTCATCGTCGGCGTGATCTCGGTGTGGGTGCCCG
ACGTCTGGGGCAACGGCTACAGCGTCGTCAACGCGATCCTGCACGCGCCGTGGACCTGGCAGGCGCTCGTCGCGGTGCTC
GTCCTCAAGCTGATCGCGACCGCCGCGACGGCGGGCTCCGGCGCGATCGGCGGGATCTTCACGCCGACACTCTTCGTCGG
CGCGGTGGTCGGCTCGCTGTTCGGCATCGCGCTGCACGCGCTGCTGCCCGCGCACGTGTCCGCGTGGTACGCGTACGCGA
TGGTCGGCATGGGCGCGTTCCTCGCGGGCGCGACGCAGGCGCCGCTGATGGCGATCCTGATGATCTTCGAGATGACGCTC
AGCTACCAGGTCGTGCTGCCGCTGATGGTGTCGTGCGTCGTCGCGTATTTCGCGGCGCGCGCGCTCGGCAAGACCTCGAT
GTACGAGATCACGCTGCGCCGCCACCGCGACGACGAGGCGCGCACGCGCCTGCGCACCGCGCAGATGCGCGACCTGATCC
AGCCGGCCGCGACCGTCGTGCCGCTCACGGCGAGCGTCGCCGACATGACGCGCGTGTTTCTCGAATATCCGGTCAAGTAC
CTGTACGTGACGGACGATGCCGGGCGCTTCCGCGGCGCGGTCGCGCTCAAGGACATCACGTCCGACCTGCTCGAGAAGCG
CGACACGACGCACAAAAGCGCGGCGAACTACCTGCATACGCCGTTTCCGCTCCTCACGCCCGACATGCCGATCGGCGCGG
CGCTCGAGCACTTCATGCGGTTCCAGGGCGAGCGGCTGCCCGTCGTCGAGCGCGCGGACGATCCGACGCTCGCGGGCGTC
GTCTACAAGACGTCGCTGCTCGATGCGTATCGCCGGATGAACATGGATCTCGAACGTTGA

Upstream 100 bases:

>100_bases
CGCCTTGCCGCGCCGCCGCGCCGCGTATGCCGGGTCCGCCCCGCGCCCGCGGCGCAATGCTATTCTTCCGCTCGATTTCA
TCCGCCGAACCTCGTCCGTC

Downstream 100 bases:

>100_bases
GCGCCCGCGCGCGGCCGGCCGGCGACCGAACGCCGCCGCGCGGCTTCGCCGGCGAAGCCGCGCCCGGGCCGGCAAAGGCG
CGCGCGCCTCGCGCAGCGGA

Product: putative voltage-gated ClC-type chloride channel ClcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MLSFLLKLRTRAQTLFRLSDAHTMLVWSVIVGIGGALATVAFREGIELIQHAISGTSGSFTEMAKRLPWQVRFWLPAAGG
FLAGCVLLVAQCGARKESKTDYMEAVALGDGVVPVRQSLWRSASSLLTIGSGGSIGREGPMVQLAALAASLVGRFAHFDP
PRLRLLVACGAAAGITSAYNAPIAGAFFVCEIVLGSIAMESFGPVVVASVVANIVMREFAGYKPPYQMPVFPAVAGWEVL
FFVALGLLCGAAAPQFLRLLELSKAQFKRLPVPLPVRLAAGGLIVGVISVWVPDVWGNGYSVVNAILHAPWTWQALVAVL
VLKLIATAATAGSGAIGGIFTPTLFVGAVVGSLFGIALHALLPAHVSAWYAYAMVGMGAFLAGATQAPLMAILMIFEMTL
SYQVVLPLMVSCVVAYFAARALGKTSMYEITLRRHRDDEARTRLRTAQMRDLIQPAATVVPLTASVADMTRVFLEYPVKY
LYVTDDAGRFRGAVALKDITSDLLEKRDTTHKSAANYLHTPFPLLTPDMPIGAALEHFMRFQGERLPVVERADDPTLAGV
VYKTSLLDAYRRMNMDLER

Sequences:

>Translated_579_residues
MLSFLLKLRTRAQTLFRLSDAHTMLVWSVIVGIGGALATVAFREGIELIQHAISGTSGSFTEMAKRLPWQVRFWLPAAGG
FLAGCVLLVAQCGARKESKTDYMEAVALGDGVVPVRQSLWRSASSLLTIGSGGSIGREGPMVQLAALAASLVGRFAHFDP
PRLRLLVACGAAAGITSAYNAPIAGAFFVCEIVLGSIAMESFGPVVVASVVANIVMREFAGYKPPYQMPVFPAVAGWEVL
FFVALGLLCGAAAPQFLRLLELSKAQFKRLPVPLPVRLAAGGLIVGVISVWVPDVWGNGYSVVNAILHAPWTWQALVAVL
VLKLIATAATAGSGAIGGIFTPTLFVGAVVGSLFGIALHALLPAHVSAWYAYAMVGMGAFLAGATQAPLMAILMIFEMTL
SYQVVLPLMVSCVVAYFAARALGKTSMYEITLRRHRDDEARTRLRTAQMRDLIQPAATVVPLTASVADMTRVFLEYPVKY
LYVTDDAGRFRGAVALKDITSDLLEKRDTTHKSAANYLHTPFPLLTPDMPIGAALEHFMRFQGERLPVVERADDPTLAGV
VYKTSLLDAYRRMNMDLER
>Mature_579_residues
MLSFLLKLRTRAQTLFRLSDAHTMLVWSVIVGIGGALATVAFREGIELIQHAISGTSGSFTEMAKRLPWQVRFWLPAAGG
FLAGCVLLVAQCGARKESKTDYMEAVALGDGVVPVRQSLWRSASSLLTIGSGGSIGREGPMVQLAALAASLVGRFAHFDP
PRLRLLVACGAAAGITSAYNAPIAGAFFVCEIVLGSIAMESFGPVVVASVVANIVMREFAGYKPPYQMPVFPAVAGWEVL
FFVALGLLCGAAAPQFLRLLELSKAQFKRLPVPLPVRLAAGGLIVGVISVWVPDVWGNGYSVVNAILHAPWTWQALVAVL
VLKLIATAATAGSGAIGGIFTPTLFVGAVVGSLFGIALHALLPAHVSAWYAYAMVGMGAFLAGATQAPLMAILMIFEMTL
SYQVVLPLMVSCVVAYFAARALGKTSMYEITLRRHRDDEARTRLRTAQMRDLIQPAATVVPLTASVADMTRVFLEYPVKY
LYVTDDAGRFRGAVALKDITSDLLEKRDTTHKSAANYLHTPFPLLTPDMPIGAALEHFMRFQGERLPVVERADDPTLAGV
VYKTSLLDAYRRMNMDLER

Specific function: Unknown

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55770840, Length=428, Percent_Identity=23.8317757009346, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI55770838, Length=429, Percent_Identity=24.2424242424242, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI189217923, Length=381, Percent_Identity=22.8346456692913, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI189217921, Length=381, Percent_Identity=22.8346456692913, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI4557473, Length=136, Percent_Identity=30.8823529411765, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI87081943, Length=421, Percent_Identity=38.9548693586698, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1786350, Length=326, Percent_Identity=27.6073619631902, Blast_Score=89, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24665008, Length=400, Percent_Identity=24, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 62231; Mature: 62231

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFLLKLRTRAQTLFRLSDAHTMLVWSVIVGIGGALATVAFREGIELIQHAISGTSGSF
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TEMAKRLPWQVRFWLPAAGGFLAGCVLLVAQCGARKESKTDYMEAVALGDGVVPVRQSLW
HHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHH
RSASSLLTIGSGGSIGREGPMVQLAALAASLVGRFAHFDPPRLRLLVACGAAAGITSAYN
HHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHCCCHHCC
APIAGAFFVCEIVLGSIAMESFGPVVVASVVANIVMREFAGYKPPYQMPVFPAVAGWEVL
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
FFVALGLLCGAAAPQFLRLLELSKAQFKRLPVPLPVRLAAGGLIVGVISVWVPDVWGNGY
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCHH
SVVNAILHAPWTWQALVAVLVLKLIATAATAGSGAIGGIFTPTLFVGAVVGSLFGIALHA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLPAHVSAWYAYAMVGMGAFLAGATQAPLMAILMIFEMTLSYQVVLPLMVSCVVAYFAAR
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGKTSMYEITLRRHRDDEARTRLRTAQMRDLIQPAATVVPLTASVADMTRVFLEYPVKY
HHCCCHHHEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
LYVTDDAGRFRGAVALKDITSDLLEKRDTTHKSAANYLHTPFPLLTPDMPIGAALEHFMR
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
FQGERLPVVERADDPTLAGVVYKTSLLDAYRRMNMDLER
HCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLSFLLKLRTRAQTLFRLSDAHTMLVWSVIVGIGGALATVAFREGIELIQHAISGTSGSF
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TEMAKRLPWQVRFWLPAAGGFLAGCVLLVAQCGARKESKTDYMEAVALGDGVVPVRQSLW
HHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHH
RSASSLLTIGSGGSIGREGPMVQLAALAASLVGRFAHFDPPRLRLLVACGAAAGITSAYN
HHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHCCCHHCC
APIAGAFFVCEIVLGSIAMESFGPVVVASVVANIVMREFAGYKPPYQMPVFPAVAGWEVL
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
FFVALGLLCGAAAPQFLRLLELSKAQFKRLPVPLPVRLAAGGLIVGVISVWVPDVWGNGY
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCHH
SVVNAILHAPWTWQALVAVLVLKLIATAATAGSGAIGGIFTPTLFVGAVVGSLFGIALHA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLPAHVSAWYAYAMVGMGAFLAGATQAPLMAILMIFEMTLSYQVVLPLMVSCVVAYFAAR
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGKTSMYEITLRRHRDDEARTRLRTAQMRDLIQPAATVVPLTASVADMTRVFLEYPVKY
HHCCCHHHEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
LYVTDDAGRFRGAVALKDITSDLLEKRDTTHKSAANYLHTPFPLLTPDMPIGAALEHFMR
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
FQGERLPVVERADDPTLAGVVYKTSLLDAYRRMNMDLER
HCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]