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The map label for this gene is xylB [H]

Identifier: 237812206

GI number: 237812206

Start: 1890732

End: 1892273

Strand: Direct

Name: xylB [H]

Synonym: GBP346_A1952

Alternate gene names: 237812206

Gene position: 1890732-1892273 (Clockwise)

Preceding gene: 237812205

Following gene: 237812207

Centisome position: 46.13

GC content: 72.5

Gene sequence:

>1542_bases
ATGGCATGCGTGATTGGTGTCGACATCGGCACCCAGAGCACGAAGGCGGTGCTCGTCGGCCTCGACGGCGCGATCCTCGC
GCAGCATGCGGTGGCGTACCGGCCGGACACGCCCAAGCCGCTGTGGGCCGAGCAGTGGCCGCACGTGTGGTTCGACGCGG
TGCGCGAATGCATCGCGCGGGTGAGCGCCGACGCGCGCGCGGCGGGCATCGGCGCCGCGTCGATCGAGGCGCTCTGCGTG
AGCAGCCTGTACGGCGGCTCGGGCATTCCGGTCGACCGCGAGATGCGGCCGCTGCATCCGTGCCTCATCTGGATGGACCG
GCGCGCGACCGACGAGGTCGACTGGGTGCGCGCGCACGTCGACGTCGCACGGCTTGGCGAGATCACGGGCAACGGCGTCG
ACAGCTACTACGGCTACACGAAGATGCTGTGGCTGCGCGAGAAGCGCCCCGACGTGTGGGCGAACGTGCGCTACTTCGTG
CCGCCGAACGCGTACGTCGCGTATCGGCTGACGGGCGAGCTCGCGGTCGATCACAGCGCGGCGGGCAACATCGGCGGCGT
CTACGATCTGGGCCGCCGCGACTGGTCCGACGAGGCGCTCGACATGCTGGGCATTCCGGCGACGATGATGCCGGAGCGGC
TCGTCGATTCGGACGCGGTGGTGGGCGGGCTGCTGCGCGAATGGGCGCACGCGCTCGGCCTCGAGGTGGGCACGCCCGTC
GTCGCGGGCGGCGTCGACGCGGCCGTCGCGACGTTCGCGGCGGGTGCGACGCGGCGCGGCCAGCACGTCGCGATGATCGG
CACGAGCATGTGCTGGGGCTACCTTGCCGAGACGGCCGACGCGCGGCGCGGGCTCGTCAGCATGCCGCACGTGTTCGACG
GCCGGCGCGACCTGTACGTGTTCGGCGGCGCGATCACGGCGGGCGCGTCGGTATCGTGGTTTCGCGAGCAGTTCTGCCAC
GCGGAAATCGAGGCCGCGCGCGCGGGCGGCGGCGACGCGCATCGCCTGCTCGAGGCTGCCGCCGCCGAGGTCAGCGCGGG
CAGCGACGGCGTGCTGTTCCTGCCGTACCTGATGGGCGAGCGCAGCCCGGTGTGGGACGCGAAGGCGAGCGGCGCGTTCG
TCGGCCTGTCGCTATATCACACGCGCGCGCATCTGTACCGCGCGGTGCTCGAAGGGCTCGCGTATGCGCTCAGGCACAAC
ATCGAGGCGGGCGCGGCCGGCGCGCGCGCGCTCGATGCGCGGCTCGTCGTGGTCGGCGGCGCCGCGCATTCGGATCTGTG
GATGCAGAGCATCGCCGACATCACCGGCTACCCGGTGTGGACGATCGCCGAGGAGGTCGAGGCGGCGATGGGCGCTGCGC
TGCTCGCCGCGCTCGGCGCGGCTCGCGTGTCGCGCGAGGCCGCGCGGCGCGGCTGGGTCACGCTCGCCGAGCGCGCGCGC
CCCGACGCGCGTCACGCGGCGTTGCACGACGCGCGCTTCGCACTGTACGCCGGGCTCTATCCGGCGCTCCAACCCTTCAT
GCACGGATTGCAGACATCATGA

Upstream 100 bases:

>100_bases
ATGGGACGAGGCGATCCGGGTCGCGAACTCGCTCGACTCGATCAAGGTGCTGATGAAGCCGCGCGGCTGAGCGCGCGGCT
CACCGGGACGCGGAGGCGAT

Downstream 100 bases:

>100_bases
GCGTCGCTTTCGATTTCCACGGCCGGTCGTTCCTCGTGACGGGCGCATCGAGCGGCATCGGCCGCGCCGCGGCCGTCGCG
CTGCGCGGCTGCGGCGCGCG

Product: carbohydrate kinase, fggy family

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MACVIGVDIGTQSTKAVLVGLDGAILAQHAVAYRPDTPKPLWAEQWPHVWFDAVRECIARVSADARAAGIGAASIEALCV
SSLYGGSGIPVDREMRPLHPCLIWMDRRATDEVDWVRAHVDVARLGEITGNGVDSYYGYTKMLWLREKRPDVWANVRYFV
PPNAYVAYRLTGELAVDHSAAGNIGGVYDLGRRDWSDEALDMLGIPATMMPERLVDSDAVVGGLLREWAHALGLEVGTPV
VAGGVDAAVATFAAGATRRGQHVAMIGTSMCWGYLAETADARRGLVSMPHVFDGRRDLYVFGGAITAGASVSWFREQFCH
AEIEAARAGGGDAHRLLEAAAAEVSAGSDGVLFLPYLMGERSPVWDAKASGAFVGLSLYHTRAHLYRAVLEGLAYALRHN
IEAGAAGARALDARLVVVGGAAHSDLWMQSIADITGYPVWTIAEEVEAAMGAALLAALGAARVSREAARRGWVTLAERAR
PDARHAALHDARFALYAGLYPALQPFMHGLQTS

Sequences:

>Translated_513_residues
MACVIGVDIGTQSTKAVLVGLDGAILAQHAVAYRPDTPKPLWAEQWPHVWFDAVRECIARVSADARAAGIGAASIEALCV
SSLYGGSGIPVDREMRPLHPCLIWMDRRATDEVDWVRAHVDVARLGEITGNGVDSYYGYTKMLWLREKRPDVWANVRYFV
PPNAYVAYRLTGELAVDHSAAGNIGGVYDLGRRDWSDEALDMLGIPATMMPERLVDSDAVVGGLLREWAHALGLEVGTPV
VAGGVDAAVATFAAGATRRGQHVAMIGTSMCWGYLAETADARRGLVSMPHVFDGRRDLYVFGGAITAGASVSWFREQFCH
AEIEAARAGGGDAHRLLEAAAAEVSAGSDGVLFLPYLMGERSPVWDAKASGAFVGLSLYHTRAHLYRAVLEGLAYALRHN
IEAGAAGARALDARLVVVGGAAHSDLWMQSIADITGYPVWTIAEEVEAAMGAALLAALGAARVSREAARRGWVTLAERAR
PDARHAALHDARFALYAGLYPALQPFMHGLQTS
>Mature_512_residues
ACVIGVDIGTQSTKAVLVGLDGAILAQHAVAYRPDTPKPLWAEQWPHVWFDAVRECIARVSADARAAGIGAASIEALCVS
SLYGGSGIPVDREMRPLHPCLIWMDRRATDEVDWVRAHVDVARLGEITGNGVDSYYGYTKMLWLREKRPDVWANVRYFVP
PNAYVAYRLTGELAVDHSAAGNIGGVYDLGRRDWSDEALDMLGIPATMMPERLVDSDAVVGGLLREWAHALGLEVGTPVV
AGGVDAAVATFAAGATRRGQHVAMIGTSMCWGYLAETADARRGLVSMPHVFDGRRDLYVFGGAITAGASVSWFREQFCHA
EIEAARAGGGDAHRLLEAAAAEVSAGSDGVLFLPYLMGERSPVWDAKASGAFVGLSLYHTRAHLYRAVLEGLAYALRHNI
EAGAAGARALDARLVVVGGAAHSDLWMQSIADITGYPVWTIAEEVEAAMGAALLAALGAARVSREAARRGWVTLAERARP
DARHAALHDARFALYAGLYPALQPFMHGLQTS

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393575, Length=449, Percent_Identity=26.0579064587973, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI42794763, Length=454, Percent_Identity=24.2290748898678, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI189409120, Length=452, Percent_Identity=24.5575221238938, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI4504007, Length=452, Percent_Identity=24.5575221238938, Blast_Score=105, Evalue=1e-22,
Organism=Escherichia coli, GI1789987, Length=508, Percent_Identity=30.1181102362205, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI1789168, Length=512, Percent_Identity=26.7578125, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1787789, Length=524, Percent_Identity=29.1984732824427, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1790005, Length=512, Percent_Identity=25.5859375, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1790361, Length=465, Percent_Identity=25.1612903225806, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1789138, Length=469, Percent_Identity=24.9466950959488, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17535599, Length=462, Percent_Identity=24.6753246753247, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI17864214, Length=470, Percent_Identity=23.6170212765957, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24657106, Length=539, Percent_Identity=25.417439703154, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24657102, Length=539, Percent_Identity=25.417439703154, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24654573, Length=423, Percent_Identity=23.1678486997636, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24655555, Length=465, Percent_Identity=23.010752688172, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24655560, Length=465, Percent_Identity=23.010752688172, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24655570, Length=465, Percent_Identity=23.010752688172, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24655574, Length=465, Percent_Identity=23.010752688172, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24655565, Length=465, Percent_Identity=23.010752688172, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356323, Length=437, Percent_Identity=25.858123569794, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 54922; Mature: 54791

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACVIGVDIGTQSTKAVLVGLDGAILAQHAVAYRPDTPKPLWAEQWPHVWFDAVRECIAR
CEEEEEECCCCCCCCEEEEECCHHHHHHHHHEECCCCCCCCCHHCCCHHHHHHHHHHHHH
VSADARAAGIGAASIEALCVSSLYGGSGIPVDREMRPLHPCLIWMDRRATDEVDWVRAHV
HCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
DVARLGEITGNGVDSYYGYTKMLWLREKRPDVWANVRYFVPPNAYVAYRLTGELAVDHSA
HHHHHHCCCCCCCHHHCCHHHEEEECCCCCCCEECEEEEECCCCEEEEEEECCEEECCCC
AGNIGGVYDLGRRDWSDEALDMLGIPATMMPERLVDSDAVVGGLLREWAHALGLEVGTPV
CCCCCCCHHCCCCCCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCE
VAGGVDAAVATFAAGATRRGQHVAMIGTSMCWGYLAETADARRGLVSMPHVFDGRRDLYV
EECCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEE
FGGAITAGASVSWFREQFCHAEIEAARAGGGDAHRLLEAAAAEVSAGSDGVLFLPYLMGE
ECCCHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHCC
RSPVWDAKASGAFVGLSLYHTRAHLYRAVLEGLAYALRHNIEAGAAGARALDARLVVVGG
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECEEEEEEEC
AAHSDLWMQSIADITGYPVWTIAEEVEAAMGAALLAALGAARVSREAARRGWVTLAERAR
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
PDARHAALHDARFALYAGLYPALQPFMHGLQTS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ACVIGVDIGTQSTKAVLVGLDGAILAQHAVAYRPDTPKPLWAEQWPHVWFDAVRECIAR
EEEEEECCCCCCCCEEEEECCHHHHHHHHHEECCCCCCCCCHHCCCHHHHHHHHHHHHH
VSADARAAGIGAASIEALCVSSLYGGSGIPVDREMRPLHPCLIWMDRRATDEVDWVRAHV
HCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
DVARLGEITGNGVDSYYGYTKMLWLREKRPDVWANVRYFVPPNAYVAYRLTGELAVDHSA
HHHHHHCCCCCCCHHHCCHHHEEEECCCCCCCEECEEEEECCCCEEEEEEECCEEECCCC
AGNIGGVYDLGRRDWSDEALDMLGIPATMMPERLVDSDAVVGGLLREWAHALGLEVGTPV
CCCCCCCHHCCCCCCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCE
VAGGVDAAVATFAAGATRRGQHVAMIGTSMCWGYLAETADARRGLVSMPHVFDGRRDLYV
EECCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEE
FGGAITAGASVSWFREQFCHAEIEAARAGGGDAHRLLEAAAAEVSAGSDGVLFLPYLMGE
ECCCHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHCC
RSPVWDAKASGAFVGLSLYHTRAHLYRAVLEGLAYALRHNIEAGAAGARALDARLVVVGG
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECEEEEEEEC
AAHSDLWMQSIADITGYPVWTIAEEVEAAMGAALLAALGAARVSREAARRGWVTLAERAR
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
PDARHAALHDARFALYAGLYPALQPFMHGLQTS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]