| Definition | Burkholderia pseudomallei MSHR346 chromosome I, complete genome. |
|---|---|
| Accession | NC_012695 |
| Length | 4,098,576 |
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The map label for this gene is yohF [C]
Identifier: 237812207
GI number: 237812207
Start: 1892270
End: 1893016
Strand: Direct
Name: yohF [C]
Synonym: GBP346_A1953
Alternate gene names: 237812207
Gene position: 1892270-1893016 (Clockwise)
Preceding gene: 237812206
Following gene: 237812208
Centisome position: 46.17
GC content: 73.09
Gene sequence:
>747_bases ATGAGCGTCGCTTTCGATTTCCACGGCCGGTCGTTCCTCGTGACGGGCGCATCGAGCGGCATCGGCCGCGCCGCGGCCGT CGCGCTGCGCGGCTGCGGCGCGCGCGTCGTCGCCGCCGCGCGCAACGCGCGCGAGCTCGAGCGGCTCGCGCACGAAACGG GCTGCGAGCCGCTCGAGCTCGACGTCGGCTGCGATGCGTCGGTGCGCGCGGCGCTTTCCGGCGAACGGATGCGCGATGCG TTCGACGGGCTGATCAATTGCGCGGGCGTGACGAGCCTTGCCGCGGCGATCGACACGACGGCCGACGAATTCGACCGCGT GATGGCCGTCAACGCGCGCGGCGCGATGCTGGTCGCGCGGCATGTCGCGCGCGCGATGATTCGCGCGGGGCGGGGCGGCA GCATCGTCAACGTATCGAGCCAGGCGGCGCTCGTCGCGCTGCCGTCGCATCTCGCCTACTGCGCGTCGAAGGCCGCGCTC GACGCGATGACGCGCGTGCTGTGCGTGGAGCTCGGGCCGCACGGCATTCGCGTGAACAGCGTCAACCCGACCGTCACGCT CACGCCGATGGCCGAGCGCGCGTGGAGCGATCCGCACGCGAGCGGGCCGATGCTCGCGGCGATTCCGCTCGGGCGCTTTG CGCGCGTCGCGGACGTCGTCGCGCCGATCCTGTTCCTGTCGAGCGACGCGGCGGCGATGGTGAGCGGCGTCGCGCTGCCG GTAGACGGCGGCTACACCGCGCGATAG
Upstream 100 bases:
>100_bases GCCCCGACGCGCGTCACGCGGCGTTGCACGACGCGCGCTTCGCACTGTACGCCGGGCTCTATCCGGCGCTCCAACCCTTC ATGCACGGATTGCAGACATC
Downstream 100 bases:
>100_bases CGCGCCCGGCGCTCGCCGGGCGTCGGGCGTCGGGCGTCGGGCGCGTTCGCGGCGCCTGGGACGAGCGTGACGCCCGGGGC GCGTGCGATGTGCGTCCCCG
Product: short chain dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 248; Mature: 247
Protein sequence:
>248_residues MSVAFDFHGRSFLVTGASSGIGRAAAVALRGCGARVVAAARNARELERLAHETGCEPLELDVGCDASVRAALSGERMRDA FDGLINCAGVTSLAAAIDTTADEFDRVMAVNARGAMLVARHVARAMIRAGRGGSIVNVSSQAALVALPSHLAYCASKAAL DAMTRVLCVELGPHGIRVNSVNPTVTLTPMAERAWSDPHASGPMLAAIPLGRFARVADVVAPILFLSSDAAAMVSGVALP VDGGYTAR
Sequences:
>Translated_248_residues MSVAFDFHGRSFLVTGASSGIGRAAAVALRGCGARVVAAARNARELERLAHETGCEPLELDVGCDASVRAALSGERMRDA FDGLINCAGVTSLAAAIDTTADEFDRVMAVNARGAMLVARHVARAMIRAGRGGSIVNVSSQAALVALPSHLAYCASKAAL DAMTRVLCVELGPHGIRVNSVNPTVTLTPMAERAWSDPHASGPMLAAIPLGRFARVADVVAPILFLSSDAAAMVSGVALP VDGGYTAR >Mature_247_residues SVAFDFHGRSFLVTGASSGIGRAAAVALRGCGARVVAAARNARELERLAHETGCEPLELDVGCDASVRAALSGERMRDAF DGLINCAGVTSLAAAIDTTADEFDRVMAVNARGAMLVARHVARAMIRAGRGGSIVNVSSQAALVALPSHLAYCASKAALD AMTRVLCVELGPHGIRVNSVNPTVTLTPMAERAWSDPHASGPMLAAIPLGRFARVADVVAPILFLSSDAAAMVSGVALPV DGGYTAR
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=47.7178423236515, Blast_Score=202, Evalue=3e-52, Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=33.8709677419355, Blast_Score=112, Evalue=4e-25, Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=34.412955465587, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=30.327868852459, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI40254992, Length=234, Percent_Identity=31.6239316239316, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI66933014, Length=246, Percent_Identity=30.8943089430894, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI4503817, Length=202, Percent_Identity=31.1881188118812, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=27.1255060728745, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI7706318, Length=183, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=29.6747967479675, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI59889578, Length=152, Percent_Identity=32.8947368421053, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI20149619, Length=184, Percent_Identity=30.4347826086957, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI4758504, Length=192, Percent_Identity=32.2916666666667, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=32.520325203252, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=31.0756972111554, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=33.0612244897959, Blast_Score=107, Evalue=8e-25, Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=29.6875, Blast_Score=105, Evalue=2e-24, Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=34, Blast_Score=104, Evalue=6e-24, Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=29.4820717131474, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=33.9920948616601, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=30.6451612903226, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1789057, Length=245, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1786701, Length=203, Percent_Identity=31.0344827586207, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=30.2788844621514, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1789378, Length=237, Percent_Identity=27.4261603375527, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1787526, Length=250, Percent_Identity=27.6, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI1787545, Length=252, Percent_Identity=27.3809523809524, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=45.4183266932271, Blast_Score=199, Evalue=1e-51, Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=33.0827067669173, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=32.2709163346614, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17555706, Length=238, Percent_Identity=31.9327731092437, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=30.3643724696356, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=34.0909090909091, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=32.7067669172932, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=32.6923076923077, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=29.2682926829268, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=31.1538461538462, Blast_Score=94, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=32.1969696969697, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=31.5789473684211, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=29.811320754717, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=28.6259541984733, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=27.2727272727273, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=26.4822134387352, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17536025, Length=254, Percent_Identity=27.5590551181102, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=29.9242424242424, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=29.5454545454545, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=30.9701492537313, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17561272, Length=233, Percent_Identity=27.8969957081545, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=28.030303030303, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=26.6393442622951, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=28.0898876404494, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=29.7794117647059, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=27.6119402985075, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI71982365, Length=213, Percent_Identity=29.5774647887324, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17538182, Length=190, Percent_Identity=30.5263157894737, Blast_Score=65, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6322067, Length=176, Percent_Identity=31.8181818181818, Blast_Score=69, Evalue=9e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=260, Percent_Identity=27.3076923076923, Blast_Score=68, Evalue=1e-12, Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=41.9753086419753, Blast_Score=172, Evalue=2e-43, Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=36.9477911646586, Blast_Score=143, Evalue=1e-34, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=37.3493975903614, Blast_Score=139, Evalue=1e-33, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=34.6613545816733, Blast_Score=126, Evalue=1e-29, Organism=Drosophila melanogaster, GI23397609, Length=242, Percent_Identity=35.1239669421488, Blast_Score=122, Evalue=3e-28, Organism=Drosophila melanogaster, GI24639444, Length=242, Percent_Identity=34.297520661157, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI24644337, Length=174, Percent_Identity=38.5057471264368, Blast_Score=104, Evalue=4e-23, Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=28.740157480315, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI21356301, Length=206, Percent_Identity=32.0388349514563, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI17737361, Length=194, Percent_Identity=33.5051546391753, Blast_Score=74, Evalue=6e-14, Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=31.1224489795918, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI28571387, Length=260, Percent_Identity=27.3076923076923, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 25479; Mature: 25347
Theoretical pI: Translated: 7.85; Mature: 7.85
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.4 %Cys (Translated Protein) 3.6 %Met (Translated Protein) 6.0 %Cys+Met (Translated Protein) 2.4 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 5.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSVAFDFHGRSFLVTGASSGIGRAAAVALRGCGARVVAAARNARELERLAHETGCEPLEL CCEEEEECCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE DVGCDASVRAALSGERMRDAFDGLINCAGVTSLAAAIDTTADEFDRVMAVNARGAMLVAR ECCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCHHHHHH HVARAMIRAGRGGSIVNVSSQAALVALPSHLAYCASKAALDAMTRVLCVELGPHGIRVNS HHHHHHHHCCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEC VNPTVTLTPMAERAWSDPHASGPMLAAIPLGRFARVADVVAPILFLSSDAAAMVSGVALP CCCEEEECCCHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHCCEEEE VDGGYTAR CCCCCCCC >Mature Secondary Structure SVAFDFHGRSFLVTGASSGIGRAAAVALRGCGARVVAAARNARELERLAHETGCEPLEL CEEEEECCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE DVGCDASVRAALSGERMRDAFDGLINCAGVTSLAAAIDTTADEFDRVMAVNARGAMLVAR ECCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCHHHHHH HVARAMIRAGRGGSIVNVSSQAALVALPSHLAYCASKAALDAMTRVLCVELGPHGIRVNS HHHHHHHHCCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEC VNPTVTLTPMAERAWSDPHASGPMLAAIPLGRFARVADVVAPILFLSSDAAAMVSGVALP CCCEEEECCCHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHCCEEEE VDGGYTAR CCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]