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The map label for this gene is ccpA [H]

Identifier: 23502897

GI number: 23502897

Start: 1974187

End: 1975245

Strand: Reverse

Name: ccpA [H]

Synonym: BR2049

Alternate gene names: 23502897

Gene position: 1975245-1974187 (Counterclockwise)

Preceding gene: 23502899

Following gene: 23502896

Centisome position: 93.71

GC content: 59.3

Gene sequence:

>1059_bases
ATGAGCAAGGGCAGCGTCACCGTTATCGACATTGCGCGCGAGGCTGGCGTGTCGAAATCGACCGTCTCTCTGGTGCTGCG
TGACAGTCCGCTGGTCCATGCCGAAACCCGCGCCAAGGTGCAGGAGGCAATCGAGAAACTGGGCTATGTCTATAACCGCT
CGGCGGCCAATCTCCGGCAGGCGAAATCGAAAATCATCGGCCTTGTGGTCAATGATCTGACCAACAGTTTCTTTGCCGAA
CTGGCGGTGGGTGTGGATCGCGTGATGCAGTCTGCGGGCTATGTGCAGTTTCTGGCCAATACGGCGGAAAGCATTGATCG
CCAGCGTGAAGTGATTGCCTCAATGCGCGAACATGGCATTGCCGGGCTGATCGTTTCGCCAGCGCGTGGAACTGAGGCCA
GTGATCTGAAACCATTGGCGAAAAGCGGCCTTCCGGTTGTGCAGATGGTGCGCGATGTGCCGGGTTCGGGTGTTTCCTCC
ATCGTTTCGGATAATCGCGGCGGCGTGGCGAAGGCGGTCGAGCATCTGGTGTCGCTGGGGCATCGCGCCATCGCTTTCAT
GGGTGGTTATGCGGATATAGCGGTGTTTTCCGAGCGTCTTGCCGGTTATCGCACAGGGTTGGAGCAAGCGGGCATTGCCT
TCGACGAGGCGCTGGTTTTCACCTCTGCGCCGTCACGCGCTGGTGGGGTTGAGGCGCTGGAACAGATGCTGCGGCAGGGC
ATGAAACCGACGGCGGCGGTGTGCTTCAACGATGCGGTTGCTTTTGGTGTCTGCGATGGCTTGCGAGCCACGCATCTGGA
ACCGGGCCGGGATTTTGGCGTCGTCGGCTTTGACGATGTGATCGAGGCAAAGACGGCTGTTCCGGCACTGACGACCGTGG
CTGTCGATCCGCAAGGTTTGGGAGAACGTGCGGCGCAGCTTTTGCTGAAACAAATCAATTCGGAACGGGTGGAGGCGGAG
GCGCAGCGTCTGTCGGTGCGTCTTGCAGTGCGTGCAAGTTGCGGCGCGCCGTTCAGAAAACCGGAGGAGAAATTTGAATG
GCAAAGTGGGGCCTTATAG

Upstream 100 bases:

>100_bases
CGGATTCGGGTTGAATCCAAAGCGGTAGGCGGTTTTTCTGTTGGGTCTTGACAGCCTTGGAACGTTCCAATTAAATCGGC
GGTCGAAACCGGAGCAGATC

Downstream 100 bases:

>100_bases
GCGCAAGCACCATTGCAAAGGAATGGGTGATCGGCACCATTCGCGCGACGGGTGGCGAGGTCGTTTCCGTCTACAGCACC
AATGCCGCGCGCGGTAAAAC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSKGSVTVIDIAREAGVSKSTVSLVLRDSPLVHAETRAKVQEAIEKLGYVYNRSAANLRQAKSKIIGLVVNDLTNSFFAE
LAVGVDRVMQSAGYVQFLANTAESIDRQREVIASMREHGIAGLIVSPARGTEASDLKPLAKSGLPVVQMVRDVPGSGVSS
IVSDNRGGVAKAVEHLVSLGHRAIAFMGGYADIAVFSERLAGYRTGLEQAGIAFDEALVFTSAPSRAGGVEALEQMLRQG
MKPTAAVCFNDAVAFGVCDGLRATHLEPGRDFGVVGFDDVIEAKTAVPALTTVAVDPQGLGERAAQLLLKQINSERVEAE
AQRLSVRLAVRASCGAPFRKPEEKFEWQSGAL

Sequences:

>Translated_352_residues
MSKGSVTVIDIAREAGVSKSTVSLVLRDSPLVHAETRAKVQEAIEKLGYVYNRSAANLRQAKSKIIGLVVNDLTNSFFAE
LAVGVDRVMQSAGYVQFLANTAESIDRQREVIASMREHGIAGLIVSPARGTEASDLKPLAKSGLPVVQMVRDVPGSGVSS
IVSDNRGGVAKAVEHLVSLGHRAIAFMGGYADIAVFSERLAGYRTGLEQAGIAFDEALVFTSAPSRAGGVEALEQMLRQG
MKPTAAVCFNDAVAFGVCDGLRATHLEPGRDFGVVGFDDVIEAKTAVPALTTVAVDPQGLGERAAQLLLKQINSERVEAE
AQRLSVRLAVRASCGAPFRKPEEKFEWQSGAL
>Mature_351_residues
SKGSVTVIDIAREAGVSKSTVSLVLRDSPLVHAETRAKVQEAIEKLGYVYNRSAANLRQAKSKIIGLVVNDLTNSFFAEL
AVGVDRVMQSAGYVQFLANTAESIDRQREVIASMREHGIAGLIVSPARGTEASDLKPLAKSGLPVVQMVRDVPGSGVSSI
VSDNRGGVAKAVEHLVSLGHRAIAFMGGYADIAVFSERLAGYRTGLEQAGIAFDEALVFTSAPSRAGGVEALEQMLRQGM
KPTAAVCFNDAVAFGVCDGLRATHLEPGRDFGVVGFDDVIEAKTAVPALTTVAVDPQGLGERAAQLLLKQINSERVEAEA
QRLSVRLAVRASCGAPFRKPEEKFEWQSGAL

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789202, Length=287, Percent_Identity=33.1010452961672, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1787906, Length=287, Percent_Identity=32.7526132404181, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1790194, Length=329, Percent_Identity=31.306990881459, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1787948, Length=336, Percent_Identity=30.3571428571429, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789068, Length=293, Percent_Identity=32.0819112627986, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788474, Length=305, Percent_Identity=29.8360655737705, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1790369, Length=328, Percent_Identity=25.9146341463415, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI48994940, Length=329, Percent_Identity=28.2674772036474, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786540, Length=335, Percent_Identity=29.5522388059701, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1790715, Length=325, Percent_Identity=24.9230769230769, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787580, Length=318, Percent_Identity=27.3584905660377, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1786268, Length=312, Percent_Identity=24.0384615384615, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790689, Length=275, Percent_Identity=25.4545454545455, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37319; Mature: 37188

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKGSVTVIDIAREAGVSKSTVSLVLRDSPLVHAETRAKVQEAIEKLGYVYNRSAANLRQ
CCCCCEEEEEEHHHCCCCHHHHEEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHH
AKSKIIGLVVNDLTNSFFAELAVGVDRVMQSAGYVQFLANTAESIDRQREVIASMREHGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
AGLIVSPARGTEASDLKPLAKSGLPVVQMVRDVPGSGVSSIVSDNRGGVAKAVEHLVSLG
EEEEECCCCCCCCHHCCHHHHCCCHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHC
HRAIAFMGGYADIAVFSERLAGYRTGLEQAGIAFDEALVFTSAPSRAGGVEALEQMLRQG
HHHHHHHCCHHHHHHHHHHHHHHHHCHHHHCCHHHHHEEEECCCCCCCCHHHHHHHHHCC
MKPTAAVCFNDAVAFGVCDGLRATHLEPGRDFGVVGFDDVIEAKTAVPALTTVAVDPQGL
CCCHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCHHHHHHHHHHCCHHEEEEECCCCH
GERAAQLLLKQINSERVEAEAQRLSVRLAVRASCGAPFRKPEEKFEWQSGAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
SKGSVTVIDIAREAGVSKSTVSLVLRDSPLVHAETRAKVQEAIEKLGYVYNRSAANLRQ
CCCCEEEEEEHHHCCCCHHHHEEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHH
AKSKIIGLVVNDLTNSFFAELAVGVDRVMQSAGYVQFLANTAESIDRQREVIASMREHGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
AGLIVSPARGTEASDLKPLAKSGLPVVQMVRDVPGSGVSSIVSDNRGGVAKAVEHLVSLG
EEEEECCCCCCCCHHCCHHHHCCCHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHC
HRAIAFMGGYADIAVFSERLAGYRTGLEQAGIAFDEALVFTSAPSRAGGVEALEQMLRQG
HHHHHHHCCHHHHHHHHHHHHHHHHCHHHHCCHHHHHEEEECCCCCCCCHHHHHHHHHCC
MKPTAAVCFNDAVAFGVCDGLRATHLEPGRDFGVVGFDDVIEAKTAVPALTTVAVDPQGL
CCCHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCHHHHHHHHHHCCHHEEEEECCCCH
GERAAQLLLKQINSERVEAEAQRLSVRLAVRASCGAPFRKPEEKFEWQSGAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]