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The map label for this gene is dppC [H]

Identifier: 23502448

GI number: 23502448

Start: 1532268

End: 1533149

Strand: Reverse

Name: dppC [H]

Synonym: BR1584

Alternate gene names: 23502448

Gene position: 1533149-1532268 (Counterclockwise)

Preceding gene: 23502449

Following gene: 23502447

Centisome position: 72.74

GC content: 58.62

Gene sequence:

>882_bases
ATGACACACTCAACTATTCAGCCGGAAGCCGTGAAGGACGTAGGCACGCTTCGTGCATTGCGGGACTTCTGGTTTTATTT
CAGCGTCAATCGCGGTGCTGTTATCGGCCTCGTTGTTTTTACGGCGCTGGTTCTTGTTGCAATCTTTGCGCCGGTTCTTG
CCCCGCATAACCCGTCGGAACAGTTCCGCGATTTCATGCTCGTGCCGCCCTTCTGGGAAGAGGGCGGTTCAACCCAGTTC
CTCCTTGGAACGGATGCGGTCGGCCGCGATATTCTTTCGCGCCTGATCTATGGCGCGCAATATTCGCTGCTCGTTGGCTT
CGTTATCGCCATCGGCGTGTTTTCCGGCTATATGGGCGGTGGCGTCGATACGGTCGCCATGCGCATCATGGACGTCATGC
TGGCATTCCCGTCGCTTTTGCTGGCGCTGGTTCTCGTCGCCATTCTCGGGCCGGGGCTGATTAATGCGGTTCTGGCGATC
ACTCTGGTTCTGCTGCCGCATTTTTCGCGCCTTACCCGCGCGGCCGTCATGGCGGAAAAGGAACGTGAATATGCAACGGC
GGCCAAGCTTGCCGGTGCAGGCAAGTTGCGCCTGATGTTCAAGACCATCCTGCCAAACTGCCTTGCGCCGCTGGTGGTGC
AGGCCACGATGTCGTTTTCCAATGCCATCCTCGACGTTGCGGCACTTGGCTTTCTTGGCATGGGGGCCCAACCGCCAACG
CCTGAATGGGGCACGATGCTTGCCGAAGCACGCGAGTTCATCATGCGCGCCTGGTGGGTCGTCACGTTCCCCGGCCTTGC
GATCCTCATCACTGTTCTCGCCATCAATCTGATCGGCGACGGTCTGCGCGATGCGCTTGATCCGAAGCTAAAGCGGAGTT
GA

Upstream 100 bases:

>100_bases
GGGCTTCTGCTGATCGCCTTCATCATTATGGTTGTGAATCTGGTCGTGGACCTGCTTTACGGCCTCATCAACCCGCGTAT
CCGGCACAAGTGAGGGGAAT

Downstream 100 bases:

>100_bases
TCGAAGTGCTACTCGATATTAAAAATCTCACGGTTTCCTTCGATACATCCACTGGCCCGTTCAAGGCGGTGGACGGGATC
GACATCACCGTTAACAAGGG

Product: dipeptide ABC transporter permease

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTHSTIQPEAVKDVGTLRALRDFWFYFSVNRGAVIGLVVFTALVLVAIFAPVLAPHNPSEQFRDFMLVPPFWEEGGSTQF
LLGTDAVGRDILSRLIYGAQYSLLVGFVIAIGVFSGYMGGGVDTVAMRIMDVMLAFPSLLLALVLVAILGPGLINAVLAI
TLVLLPHFSRLTRAAVMAEKEREYATAAKLAGAGKLRLMFKTILPNCLAPLVVQATMSFSNAILDVAALGFLGMGAQPPT
PEWGTMLAEAREFIMRAWWVVTFPGLAILITVLAINLIGDGLRDALDPKLKRS

Sequences:

>Translated_293_residues
MTHSTIQPEAVKDVGTLRALRDFWFYFSVNRGAVIGLVVFTALVLVAIFAPVLAPHNPSEQFRDFMLVPPFWEEGGSTQF
LLGTDAVGRDILSRLIYGAQYSLLVGFVIAIGVFSGYMGGGVDTVAMRIMDVMLAFPSLLLALVLVAILGPGLINAVLAI
TLVLLPHFSRLTRAAVMAEKEREYATAAKLAGAGKLRLMFKTILPNCLAPLVVQATMSFSNAILDVAALGFLGMGAQPPT
PEWGTMLAEAREFIMRAWWVVTFPGLAILITVLAINLIGDGLRDALDPKLKRS
>Mature_292_residues
THSTIQPEAVKDVGTLRALRDFWFYFSVNRGAVIGLVVFTALVLVAIFAPVLAPHNPSEQFRDFMLVPPFWEEGGSTQFL
LGTDAVGRDILSRLIYGAQYSLLVGFVIAIGVFSGYMGGGVDTVAMRIMDVMLAFPSLLLALVLVAILGPGLINAVLAIT
LVLLPHFSRLTRAAVMAEKEREYATAAKLAGAGKLRLMFKTILPNCLAPLVVQATMSFSNAILDVAALGFLGMGAQPPTP
EWGTMLAEAREFIMRAWWVVTFPGLAILITVLAINLIGDGLRDALDPKLKRS

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=282, Percent_Identity=64.1843971631206, Blast_Score=325, Evalue=2e-90,
Organism=Escherichia coli, GI1787760, Length=265, Percent_Identity=43.7735849056604, Blast_Score=219, Evalue=1e-58,
Organism=Escherichia coli, GI1787549, Length=276, Percent_Identity=43.4782608695652, Blast_Score=212, Evalue=2e-56,
Organism=Escherichia coli, GI1787054, Length=295, Percent_Identity=40.6779661016949, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1789889, Length=223, Percent_Identity=39.4618834080717, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1787498, Length=272, Percent_Identity=33.8235294117647, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788505, Length=225, Percent_Identity=30.6666666666667, Blast_Score=95, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31634; Mature: 31503

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHSTIQPEAVKDVGTLRALRDFWFYFSVNRGAVIGLVVFTALVLVAIFAPVLAPHNPSE
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHH
QFRDFMLVPPFWEEGGSTQFLLGTDAVGRDILSRLIYGAQYSLLVGFVIAIGVFSGYMGG
HHHCCCCCCCHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVDTVAMRIMDVMLAFPSLLLALVLVAILGPGLINAVLAITLVLLPHFSRLTRAAVMAEK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EREYATAAKLAGAGKLRLMFKTILPNCLAPLVVQATMSFSNAILDVAALGFLGMGAQPPT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PEWGTMLAEAREFIMRAWWVVTFPGLAILITVLAINLIGDGLRDALDPKLKRS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
THSTIQPEAVKDVGTLRALRDFWFYFSVNRGAVIGLVVFTALVLVAIFAPVLAPHNPSE
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHH
QFRDFMLVPPFWEEGGSTQFLLGTDAVGRDILSRLIYGAQYSLLVGFVIAIGVFSGYMGG
HHHCCCCCCCHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVDTVAMRIMDVMLAFPSLLLALVLVAILGPGLINAVLAITLVLLPHFSRLTRAAVMAEK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EREYATAAKLAGAGKLRLMFKTILPNCLAPLVVQATMSFSNAILDVAALGFLGMGAQPPT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PEWGTMLAEAREFIMRAWWVVTFPGLAILITVLAINLIGDGLRDALDPKLKRS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]