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The map label for this gene is dppB [H]

Identifier: 23502449

GI number: 23502449

Start: 1533157

End: 1534164

Strand: Reverse

Name: dppB [H]

Synonym: BR1585

Alternate gene names: 23502449

Gene position: 1534164-1533157 (Counterclockwise)

Preceding gene: 23502451

Following gene: 23502448

Centisome position: 72.79

GC content: 55.46

Gene sequence:

>1008_bases
ATGTTCCGTTTCATATTAAACAAACTTGTCTATCTGGTTCCGACCTTCATAGGCATTACAATTGTGGCTTTCGCTTTCGT
GCGGGTCCTGCCCGGCGATCCCGTGCTGCTGATGGCCGGCGAACGGGGTGTGAGTCCTGAACGCCATGCTGAACTCATGG
CGCAGCTCGGATTTGATCGTCCGATCTGGGAGCAATATCTCCTTTATGTCTGGAACTTGCTGCACGGCGATTTCGGTCAG
TCTCTGGTGACGAAAAAGCCTGTCCTAGTGGAATTTTTCGCGCTTTTTTCTGCAACCGTCGAGTTGTCCATCTGCGCGAT
TATCCTGGCTGTCCTCATTGGCATTCCTGCCGGCGTCATCGCTGCCGTCAAGCGCGGCTCCTGGTTCGATCAGGGGCTTA
TGGGCATTTCACTGGTCGGTTATTCGATGCCGATTTTCTGGTGGGCGCTGCTTCTCATCATCTTCTTCTCCGGTGTTTTG
CAGTGGACCCCCGTTTCGGGCCGCATTTCGCTTCTCTATTATTTCACTCCCGTTTCGGGCTTCATGCTGATCGACAGCCT
GCTTTCGGGCCAGAAGGGCGCTTTCCTGTCGGCTGCTTCGCATCTCATCTTGCCGACCATCGTGCTTGCGACCATTCCGC
TTGCGGTGATTGCGCGCCAGACCCGTTCGGCGATGCTGGAAGTTCTGGGCGAAGATTATGTGCGTACTGCGCGCGCCAAG
GGCCTTCCCATACGCCGCATTGTCGGTCTTCATGCGCTGCGCAATGCGATGATCCCGGTCATCACGACAATCGGCCTGCA
GGTCGGCGTGTTGATGGCGGGCGCAATCCTGACCGAAACAATTTTCTCATGGCCCGGTATCGGTAAATGGATGCTCGATT
CCATTTCGCGCCGCGATTATCCGGTCGTTCAGAGCGGGCTTCTGCTGATCGCCTTCATCATTATGGTTGTGAATCTGGTC
GTGGACCTGCTTTACGGCCTCATCAACCCGCGTATCCGGCACAAGTGA

Upstream 100 bases:

>100_bases
GAATTCGTTCATGTCTCCTTTCAGGAGGCATACGGGTTTCGGTTTCATCAAATCCGTGGCCGGGTGTGGGGAACCCTCTG
CGCCCGGTCGGAGTTTTTTT

Downstream 100 bases:

>100_bases
GGGGAATATGACACACTCAACTATTCAGCCGGAAGCCGTGAAGGACGTAGGCACGCTTCGTGCATTGCGGGACTTCTGGT
TTTATTTCAGCGTCAATCGC

Product: dipeptide ABC transporter permease

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MFRFILNKLVYLVPTFIGITIVAFAFVRVLPGDPVLLMAGERGVSPERHAELMAQLGFDRPIWEQYLLYVWNLLHGDFGQ
SLVTKKPVLVEFFALFSATVELSICAIILAVLIGIPAGVIAAVKRGSWFDQGLMGISLVGYSMPIFWWALLLIIFFSGVL
QWTPVSGRISLLYYFTPVSGFMLIDSLLSGQKGAFLSAASHLILPTIVLATIPLAVIARQTRSAMLEVLGEDYVRTARAK
GLPIRRIVGLHALRNAMIPVITTIGLQVGVLMAGAILTETIFSWPGIGKWMLDSISRRDYPVVQSGLLLIAFIIMVVNLV
VDLLYGLINPRIRHK

Sequences:

>Translated_335_residues
MFRFILNKLVYLVPTFIGITIVAFAFVRVLPGDPVLLMAGERGVSPERHAELMAQLGFDRPIWEQYLLYVWNLLHGDFGQ
SLVTKKPVLVEFFALFSATVELSICAIILAVLIGIPAGVIAAVKRGSWFDQGLMGISLVGYSMPIFWWALLLIIFFSGVL
QWTPVSGRISLLYYFTPVSGFMLIDSLLSGQKGAFLSAASHLILPTIVLATIPLAVIARQTRSAMLEVLGEDYVRTARAK
GLPIRRIVGLHALRNAMIPVITTIGLQVGVLMAGAILTETIFSWPGIGKWMLDSISRRDYPVVQSGLLLIAFIIMVVNLV
VDLLYGLINPRIRHK
>Mature_335_residues
MFRFILNKLVYLVPTFIGITIVAFAFVRVLPGDPVLLMAGERGVSPERHAELMAQLGFDRPIWEQYLLYVWNLLHGDFGQ
SLVTKKPVLVEFFALFSATVELSICAIILAVLIGIPAGVIAAVKRGSWFDQGLMGISLVGYSMPIFWWALLLIIFFSGVL
QWTPVSGRISLLYYFTPVSGFMLIDSLLSGQKGAFLSAASHLILPTIVLATIPLAVIARQTRSAMLEVLGEDYVRTARAK
GLPIRRIVGLHALRNAMIPVITTIGLQVGVLMAGAILTETIFSWPGIGKWMLDSISRRDYPVVQSGLLLIAFIIMVVNLV
VDLLYGLINPRIRHK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=61.5384615384615, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1787053, Length=339, Percent_Identity=40.7079646017699, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1787761, Length=316, Percent_Identity=47.1518987341772, Blast_Score=238, Evalue=6e-64,
Organism=Escherichia coli, GI1787550, Length=277, Percent_Identity=38.6281588447653, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1789888, Length=337, Percent_Identity=35.0148367952522, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1787497, Length=335, Percent_Identity=35.2238805970149, Blast_Score=198, Evalue=4e-52,
Organism=Escherichia coli, GI1788504, Length=299, Percent_Identity=32.1070234113712, Blast_Score=144, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36978; Mature: 36978

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRFILNKLVYLVPTFIGITIVAFAFVRVLPGDPVLLMAGERGVSPERHAELMAQLGFDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCC
PIWEQYLLYVWNLLHGDFGQSLVTKKPVLVEFFALFSATVELSICAIILAVLIGIPAGVI
HHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AAVKRGSWFDQGLMGISLVGYSMPIFWWALLLIIFFSGVLQWTPVSGRISLLYYFTPVSG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHH
FMLIDSLLSGQKGAFLSAASHLILPTIVLATIPLAVIARQTRSAMLEVLGEDYVRTARAK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLPIRRIVGLHALRNAMIPVITTIGLQVGVLMAGAILTETIFSWPGIGKWMLDSISRRDY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
PVVQSGLLLIAFIIMVVNLVVDLLYGLINPRIRHK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFRFILNKLVYLVPTFIGITIVAFAFVRVLPGDPVLLMAGERGVSPERHAELMAQLGFDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCC
PIWEQYLLYVWNLLHGDFGQSLVTKKPVLVEFFALFSATVELSICAIILAVLIGIPAGVI
HHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AAVKRGSWFDQGLMGISLVGYSMPIFWWALLLIIFFSGVLQWTPVSGRISLLYYFTPVSG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHH
FMLIDSLLSGQKGAFLSAASHLILPTIVLATIPLAVIARQTRSAMLEVLGEDYVRTARAK
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLPIRRIVGLHALRNAMIPVITTIGLQVGVLMAGAILTETIFSWPGIGKWMLDSISRRDY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
PVVQSGLLLIAFIIMVVNLVVDLLYGLINPRIRHK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]