Click here to switch to the map view.

The map label for this gene is murB [H]

Identifier: 23502300

GI number: 23502300

Start: 1385647

End: 1386615

Strand: Reverse

Name: murB [H]

Synonym: BR1429

Alternate gene names: 23502300

Gene position: 1386615-1385647 (Counterclockwise)

Preceding gene: 23502301

Following gene: 23502299

Centisome position: 65.79

GC content: 61.3

Gene sequence:

>969_bases
ATGATGGAAAGCGGCGAGGCGCTTCTAAAGAAGCTCGACGGCAGGCTGTCTGGCTTGCGCGGGCGGCTTACGCCCGATAC
GGGCATGGACAAGATCACCTGGTTTCGCGCAGGCGGGCCGGCGCAGGTTCTGTTCCAGCCGTCCGACGAGGAAGACCTCT
CCGCATTTCTGAAAGCCGTGCCGGAAGAAATACCGCTTCTCGTGGTGGGGATCGGCTCCAATCTTCTGGTGCGTGACGGC
GGTGTGCCGGGCTTCGTGGTCCGGCTTTCGGCCAAGGGCTTTGGTGAGGTCGAACAGGTTTGCGATACGCAGTTGCGGGC
AGGGGCGGCAGCGCCCGACAAGCGCGTGGCCGCAGCAGCCCTCGAAGCGGGCCTGGCGGGCTTTCATTTCTATCATGGCA
TTCCCGGCGGGGTCGGTGGAGCACTGCGCATGAATGCGGGCGCAAACGGCGTGGAAACGCGCGAGCGCGTGGTGGAAGTG
CGCGCGCTTGACCGCAAGGGGGAGGTGCATGTGCTTTCAAATGCCGATATGGGCTATGCCTATCGCCATTCCTCGGCGTC
GCCCGATCTGATTTTCACCTCGGTCCTGTTTGAAGGCGTGCCGGGTGAGCGCGATGACATCCGCCGCGCGATGGACGAAG
TGCAGCATCATCGCGAAACGGTGCAGCCGGTGCGCGAGAAGACCGGCGGCTCGACCTTCAAGAACCCGGAAGGGACGTCC
GCGTGGAAGGAAATCGACAAGGCGGGATGCCGTGGCCTGCGTGTCGGCGGTGCGCAGATGTCGGAAATGCACTGCAACTT
CATGATCAATACGGGCAATGCCACGGGGCATGATCTGGAGACTTTGGGCGAAACGGTTCGCGCAAGGGTTTTCGAGAATT
CGGGGATTCGCCTGCACTGGGAAATCAAACGTCTCGGTTTGTTCCGCGAAGGGGAGCAGATCGAGGAGTTTCTTGGAAAA
ATAATATAA

Upstream 100 bases:

>100_bases
TCGCGCAAGCGGGTGATTTCGTCGTCTGCCTCGGTGCGGGCAATGTCACGCAATGGGCCTATGCCCTGCCGAAGGAACTG
GCCGAACAGGGTAAGAAATA

Downstream 100 bases:

>100_bases
AAAAGTTGCCCGGATTTTCCCCCTGAAATTCCGGGCTTTTTTAGCCTTGCAAGCTGGCCGCAAGGTTTGTCCCTTTCTAT
AGGGTCTTGTCACGGAATCA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MMESGEALLKKLDGRLSGLRGRLTPDTGMDKITWFRAGGPAQVLFQPSDEEDLSAFLKAVPEEIPLLVVGIGSNLLVRDG
GVPGFVVRLSAKGFGEVEQVCDTQLRAGAAAPDKRVAAAALEAGLAGFHFYHGIPGGVGGALRMNAGANGVETRERVVEV
RALDRKGEVHVLSNADMGYAYRHSSASPDLIFTSVLFEGVPGERDDIRRAMDEVQHHRETVQPVREKTGGSTFKNPEGTS
AWKEIDKAGCRGLRVGGAQMSEMHCNFMINTGNATGHDLETLGETVRARVFENSGIRLHWEIKRLGLFREGEQIEEFLGK
II

Sequences:

>Translated_322_residues
MMESGEALLKKLDGRLSGLRGRLTPDTGMDKITWFRAGGPAQVLFQPSDEEDLSAFLKAVPEEIPLLVVGIGSNLLVRDG
GVPGFVVRLSAKGFGEVEQVCDTQLRAGAAAPDKRVAAAALEAGLAGFHFYHGIPGGVGGALRMNAGANGVETRERVVEV
RALDRKGEVHVLSNADMGYAYRHSSASPDLIFTSVLFEGVPGERDDIRRAMDEVQHHRETVQPVREKTGGSTFKNPEGTS
AWKEIDKAGCRGLRVGGAQMSEMHCNFMINTGNATGHDLETLGETVRARVFENSGIRLHWEIKRLGLFREGEQIEEFLGK
II
>Mature_322_residues
MMESGEALLKKLDGRLSGLRGRLTPDTGMDKITWFRAGGPAQVLFQPSDEEDLSAFLKAVPEEIPLLVVGIGSNLLVRDG
GVPGFVVRLSAKGFGEVEQVCDTQLRAGAAAPDKRVAAAALEAGLAGFHFYHGIPGGVGGALRMNAGANGVETRERVVEV
RALDRKGEVHVLSNADMGYAYRHSSASPDLIFTSVLFEGVPGERDDIRRAMDEVQHHRETVQPVREKTGGSTFKNPEGTS
AWKEIDKAGCRGLRVGGAQMSEMHCNFMINTGNATGHDLETLGETVRARVFENSGIRLHWEIKRLGLFREGEQIEEFLGK
II

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 34891; Mature: 34891

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMESGEALLKKLDGRLSGLRGRLTPDTGMDKITWFRAGGPAQVLFQPSDEEDLSAFLKAV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHC
PEEIPLLVVGIGSNLLVRDGGVPGFVVRLSAKGFGEVEQVCDTQLRAGAAAPDKRVAAAA
CCCCCEEEEECCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
LEAGLAGFHFYHGIPGGVGGALRMNAGANGVETRERVVEVRALDRKGEVHVLSNADMGYA
HHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCEE
YRHSSASPDLIFTSVLFEGVPGERDDIRRAMDEVQHHRETVQPVREKTGGSTFKNPEGTS
EECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
AWKEIDKAGCRGLRVGGAQMSEMHCNFMINTGNATGHDLETLGETVRARVFENSGIRLHW
HHHHHHHHCCCEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEE
EIKRLGLFREGEQIEEFLGKII
EEEECCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MMESGEALLKKLDGRLSGLRGRLTPDTGMDKITWFRAGGPAQVLFQPSDEEDLSAFLKAV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHC
PEEIPLLVVGIGSNLLVRDGGVPGFVVRLSAKGFGEVEQVCDTQLRAGAAAPDKRVAAAA
CCCCCEEEEECCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
LEAGLAGFHFYHGIPGGVGGALRMNAGANGVETRERVVEVRALDRKGEVHVLSNADMGYA
HHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCEE
YRHSSASPDLIFTSVLFEGVPGERDDIRRAMDEVQHHRETVQPVREKTGGSTFKNPEGTS
EECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
AWKEIDKAGCRGLRVGGAQMSEMHCNFMINTGNATGHDLETLGETVRARVFENSGIRLHW
HHHHHHHHCCCEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEE
EIKRLGLFREGEQIEEFLGKII
EEEECCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA