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The map label for this gene is cat1 [H]

Identifier: 23100570

GI number: 23100570

Start: 3245442

End: 3246956

Strand: Reverse

Name: cat1 [H]

Synonym: OB3115

Alternate gene names: 23100570

Gene position: 3246956-3245442 (Counterclockwise)

Preceding gene: 23100571

Following gene: 23100569

Centisome position: 89.43

GC content: 41.78

Gene sequence:

>1515_bases
ATGGAAGAAAAATTAAAGCGCATACAAAACAAGGAATTAGGGCAAAAAGTGGTAACTGCAGCAGAAGCAGCTTCTTGGAT
TAAAGATGGTATGACATTGGGGCTTAGTGGATTTACACGTGCGGGAGATGCAAAGGCGGTTCCGACTGCGCTGGTGAAAA
GAGCGGAAGCGGGAGAATCCCTCAAAGTCAATGTATACACAGGGGCATCTTTAGGATCTAATATCGATAAGCTGTTTGCA
GAAGCAGGAATCGTTAATAAAAGAATTCCATTTCAGGCTGAGCCATCTATGCGTAAGGCAATAAATGCTGGGGAACATTT
ATTTGTCGACCAACACCTTTCACACACATCAGAAATGCTTCGTGGTGATGCGATGGAGGCTGTCGATTATGCCATAATAG
AAGCAATTTCTGTAACAGAAAATGGTTATATTATTCCAAGTACATCAGTAGGTAACTCAGTTGCATTTGCTGAAACTGCC
GATAACATTATTATTGAACTCAATACTGCGCAACCAATGGAATTAGAAGGAATGCATGATATTTATGGTCCTGGGAAACA
AGGAGATCGTGATCCGATTCCATTAAAAGAGGTCGATCAGCGTATTGGTAAGGTCGGTATTCAGGTTGATACGGATAAAA
TTAAGGGGATAGTTTTTACGCATCAACCTGATTCAGCTTCGACAATTGTTCCGCCAGATGAGGAGACGCAACAAATTGCG
AACCATCTACTGAATTTCTTTAGGGAGGAGATTCAGGCAGGACGATTAACAGAGAAGCTTATGCCATTGCAGTCCGGAAT
AGGTTCTGTTGCTAATGCCGTATTACATGGTATGCTAGACTCTGAGTTTAAAGATTTGACGGTTTATTCTGAAGTGCTTC
AAGATGCTGTCTTCGATTTGATTGATGCAGGTAAAGTGAGCTTTGCTTCTGCATGTTCCATTACGTTATCAGAAGACAAG
ATGAAGCATGTGTTTAGTAATCTAGCGGAATATCAGAGTAAGCTTGTCTTACGTCCGCAAGAAATCTCGAATCATCCAGA
AATCATTCGTCGACTGGGTCTAATTGCGATTAACACAGCATTAGAATTTGATATTTACGGCAATGTGAACTCTACACACG
TTGGCGGAACGAAAATGATGAACGGTATTGGTGGTTCAGGCGATTTTGCTAGAAATGCTAGATTGGGGATTTTTGTTACA
AAGTCGATTGCGAAAAATGGCGATATATCTAGTATCGTTCCATATGTATCGCATACAGATCATACCGAACACGATGTAGA
TGTAATTGTTACGGAACAAGGTTATGCAGACCTTCGTGGATTAGCACCACGAGAACGAGTGCCGCAAATTATTGAAAATT
GTGTGCATCCTTTATATAAGGAAGCGTTATGGGAGTATTACCAAGAAGCGCTAGAACGGGGTGGGCAGACTCCGCATGTT
CTAGAAAAAGCTTTTTCTTGGCATGCTAACTTCCGAGAGCATGGAACAATGCTGCCGGCAGTGCCACAAGTGTAA

Upstream 100 bases:

>100_bases
ATATTAAGCGCATTATTCTTTTTTTCTTCTAAATCTCCCGATTAATTAGAAAAATCAGTTAAGATGAAAGAACAATTGCA
AAAAGGGGGGGAGGATTAGG

Downstream 100 bases:

>100_bases
GACAAAAGGGGATATTATATTAGAAGACACATGTATAGCGGGCAGGCTATTCATGTGTCTTTTTGGTGTGTTAGGAAATG
ATAACATTTTGCATCTGTGG

Product: coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MEEKLKRIQNKELGQKVVTAAEAASWIKDGMTLGLSGFTRAGDAKAVPTALVKRAEAGESLKVNVYTGASLGSNIDKLFA
EAGIVNKRIPFQAEPSMRKAINAGEHLFVDQHLSHTSEMLRGDAMEAVDYAIIEAISVTENGYIIPSTSVGNSVAFAETA
DNIIIELNTAQPMELEGMHDIYGPGKQGDRDPIPLKEVDQRIGKVGIQVDTDKIKGIVFTHQPDSASTIVPPDEETQQIA
NHLLNFFREEIQAGRLTEKLMPLQSGIGSVANAVLHGMLDSEFKDLTVYSEVLQDAVFDLIDAGKVSFASACSITLSEDK
MKHVFSNLAEYQSKLVLRPQEISNHPEIIRRLGLIAINTALEFDIYGNVNSTHVGGTKMMNGIGGSGDFARNARLGIFVT
KSIAKNGDISSIVPYVSHTDHTEHDVDVIVTEQGYADLRGLAPRERVPQIIENCVHPLYKEALWEYYQEALERGGQTPHV
LEKAFSWHANFREHGTMLPAVPQV

Sequences:

>Translated_504_residues
MEEKLKRIQNKELGQKVVTAAEAASWIKDGMTLGLSGFTRAGDAKAVPTALVKRAEAGESLKVNVYTGASLGSNIDKLFA
EAGIVNKRIPFQAEPSMRKAINAGEHLFVDQHLSHTSEMLRGDAMEAVDYAIIEAISVTENGYIIPSTSVGNSVAFAETA
DNIIIELNTAQPMELEGMHDIYGPGKQGDRDPIPLKEVDQRIGKVGIQVDTDKIKGIVFTHQPDSASTIVPPDEETQQIA
NHLLNFFREEIQAGRLTEKLMPLQSGIGSVANAVLHGMLDSEFKDLTVYSEVLQDAVFDLIDAGKVSFASACSITLSEDK
MKHVFSNLAEYQSKLVLRPQEISNHPEIIRRLGLIAINTALEFDIYGNVNSTHVGGTKMMNGIGGSGDFARNARLGIFVT
KSIAKNGDISSIVPYVSHTDHTEHDVDVIVTEQGYADLRGLAPRERVPQIIENCVHPLYKEALWEYYQEALERGGQTPHV
LEKAFSWHANFREHGTMLPAVPQV
>Mature_504_residues
MEEKLKRIQNKELGQKVVTAAEAASWIKDGMTLGLSGFTRAGDAKAVPTALVKRAEAGESLKVNVYTGASLGSNIDKLFA
EAGIVNKRIPFQAEPSMRKAINAGEHLFVDQHLSHTSEMLRGDAMEAVDYAIIEAISVTENGYIIPSTSVGNSVAFAETA
DNIIIELNTAQPMELEGMHDIYGPGKQGDRDPIPLKEVDQRIGKVGIQVDTDKIKGIVFTHQPDSASTIVPPDEETQQIA
NHLLNFFREEIQAGRLTEKLMPLQSGIGSVANAVLHGMLDSEFKDLTVYSEVLQDAVFDLIDAGKVSFASACSITLSEDK
MKHVFSNLAEYQSKLVLRPQEISNHPEIIRRLGLIAINTALEFDIYGNVNSTHVGGTKMMNGIGGSGDFARNARLGIFVT
KSIAKNGDISSIVPYVSHTDHTEHDVDVIVTEQGYADLRGLAPRERVPQIIENCVHPLYKEALWEYYQEALERGGQTPHV
LEKAFSWHANFREHGTMLPAVPQV

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=486, Percent_Identity=42.798353909465, Blast_Score=400, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17538151, Length=398, Percent_Identity=25.1256281407035, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32563853, Length=230, Percent_Identity=30.8695652173913, Blast_Score=76, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6319456, Length=512, Percent_Identity=43.1640625, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 55166; Mature: 55166

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEKLKRIQNKELGQKVVTAAEAASWIKDGMTLGLSGFTRAGDAKAVPTALVKRAEAGES
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCC
LKVNVYTGASLGSNIDKLFAEAGIVNKRIPFQAEPSMRKAINAGEHLFVDQHLSHTSEML
EEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEHHHHHHHHHHHH
RGDAMEAVDYAIIEAISVTENGYIIPSTSVGNSVAFAETADNIIIELNTAQPMELEGMHD
HCCHHHHHHHHHHHHHEECCCCEEEECCCCCCCEEEEECCCCEEEEECCCCCCCCCCCHH
IYGPGKQGDRDPIPLKEVDQRIGKVGIQVDTDKIKGIVFTHQPDSASTIVPPDEETQQIA
HCCCCCCCCCCCCCHHHHHHHHHHCCCEEEHHHCCEEEEEECCCCCCCCCCCCHHHHHHH
NHLLNFFREEIQAGRLTEKLMPLQSGIGSVANAVLHGMLDSEFKDLTVYSEVLQDAVFDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDAGKVSFASACSITLSEDKMKHVFSNLAEYQSKLVLRPQEISNHPEIIRRLGLIAINTA
HHCCCCCHHHHEEEEECHHHHHHHHHHHHHHHHHEECCHHHHCCCHHHHHHHHHHEEECE
LEFDIYGNVNSTHVGGTKMMNGIGGSGDFARNARLGIFVTKSIAKNGDISSIVPYVSHTD
EEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEEHHHHCCCCHHHHHHHHCCCC
HTEHDVDVIVTEQGYADLRGLAPRERVPQIIENCVHPLYKEALWEYYQEALERGGQTPHV
CCCCCCEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LEKAFSWHANFREHGTMLPAVPQV
HHHHHHHCCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MEEKLKRIQNKELGQKVVTAAEAASWIKDGMTLGLSGFTRAGDAKAVPTALVKRAEAGES
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCC
LKVNVYTGASLGSNIDKLFAEAGIVNKRIPFQAEPSMRKAINAGEHLFVDQHLSHTSEML
EEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEHHHHHHHHHHHH
RGDAMEAVDYAIIEAISVTENGYIIPSTSVGNSVAFAETADNIIIELNTAQPMELEGMHD
HCCHHHHHHHHHHHHHEECCCCEEEECCCCCCCEEEEECCCCEEEEECCCCCCCCCCCHH
IYGPGKQGDRDPIPLKEVDQRIGKVGIQVDTDKIKGIVFTHQPDSASTIVPPDEETQQIA
HCCCCCCCCCCCCCHHHHHHHHHHCCCEEEHHHCCEEEEEECCCCCCCCCCCCHHHHHHH
NHLLNFFREEIQAGRLTEKLMPLQSGIGSVANAVLHGMLDSEFKDLTVYSEVLQDAVFDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDAGKVSFASACSITLSEDKMKHVFSNLAEYQSKLVLRPQEISNHPEIIRRLGLIAINTA
HHCCCCCHHHHEEEEECHHHHHHHHHHHHHHHHHEECCHHHHCCCHHHHHHHHHHEEECE
LEFDIYGNVNSTHVGGTKMMNGIGGSGDFARNARLGIFVTKSIAKNGDISSIVPYVSHTD
EEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEEHHHHCCCCHHHHHHHHCCCC
HTEHDVDVIVTEQGYADLRGLAPRERVPQIIENCVHPLYKEALWEYYQEALERGGQTPHV
CCCCCCEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LEKAFSWHANFREHGTMLPAVPQV
HHHHHHHCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]