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The map label for this gene is sdcS [H]

Identifier: 23099995

GI number: 23099995

Start: 2594222

End: 2595880

Strand: Direct

Name: sdcS [H]

Synonym: OB2540

Alternate gene names: 23099995

Gene position: 2594222-2595880 (Clockwise)

Preceding gene: 23099986

Following gene: 23100001

Centisome position: 71.46

GC content: 37.49

Gene sequence:

>1659_bases
ATGTTACATGCAACGTGGTATTGGATGTGGGAGAAACATGATCAAGTCAAGGACCTGTTTCGTTTATTTGTGAACCCAAA
TGAAATTATCGAAAAGAATAAAAAAGATAGTACTCCATCATCCACAACGAGTAATAGTAATAACGGGGATGATGGTGGAA
ATAATCGTCAATATAACAAAGCTCAACTAATCGGATTATTTCTTGGACCAATTTCATTTATATTAACGCTGTTATTCTTT
TCCCCAGAAGGATTAAGCAGTGAAGGTCAAGCAGTACTCGCGAGTACCATCTGGATAGCTATTTGGTGGATGACAGAAGC
CATTCCAATTCCTGCTACTGCATTATTACCAATAATCCTTTTTCCACTCACAAATGGATTAGACATTGGAGCAACAACAT
CTGCCTATGGCAGCGATACCATTTTCCTATTCATGGGAGGATTTGTCATAGCGCTTGCGATGGAACGATGGAATTTACAT
AGAAGAATTGCTATTAGCATTATATCCGTAATTGGCACCAATACCGATCGAATTATATTAGGATTTATGGTAGCTACTGG
GTTTCTATCCATGTTTATTTCTAATACAGCTACTGCAATGATGATGGTACCTATTGGATTAGCAATCATTTATCAAGTTT
CTGATACGCTAAAGGAACAAGGGGGATTTGATACCAGCCCAGAAAACTTTTCATTTGGGAAGTCATTAATGCTGGGGATC
GCCTATTCAGCTTCAATCGGTGGAATGGCAACATTAATTGGAACTCCACCAAACGTAATTTTTGCAGGTACAATTAATAC
TATGTATGGTATTGAAGTTTCTTTTGCATCTTGGATGATGTTCGGTGTACCTTTTGCATGGATATTTATATTCCTGACAT
GGTTCTATCTATCGAAAATAGCATTCAAACTAGAAGTTAGCCATATTCCTGGTGGCGCAAAGATAATCAAAGAAGAAAAG
AAAAAGCTTGGGAATGCTTCTTATGAAGAAAAAGCTGTATTTGTCGTATTTATCTTAGCTGCGATCGCTTGGATTTCTCG
TGAATTTTTATTAGGCCCTTATGTAAGCGAGAATATCAATGATGCAATTATTGCCATTACAGCTGCTTTAGTACTATTCT
TAATACCTGCCAAGAATAAAAAAGGTGATTTTCTTATGAATTGGGAAAGTGCTATAAAACTACCATGGGGAATCCTGTTA
CTATTTGGCGGAGGTTTAGCTATTGCTGCAGGTTTTACCGATTCAGGACTATCAGATTGGATTGGGGAACAACTTACTGG
CTTAGAAAATGTCGCACCTATTATTATTATTCTATCTATTGCAGCACTTGTAATCTTCTTAACTGAAATCACATCTAATA
CAGCAACAGCTACGATGATGTTTCCGATTATGGCAGCATTAGCAGTCGCAGTGGGAGTTCATCCGTTTATTCTAATGATT
GCTGCAGCATTAGCAGCCTCCTGTGCATTTATGTTACCAGTTGCAACACCCCCAAATGCTGTTGTATTTGGATCTGGGTA
TTTAAGAATACCAGATATGGCAAAGGCTGGTTTTTTCCTTAATATTGTTGGGATTATACTAGTAACATTAACCGTATATT
TCCTTGTACCAATGGCACTAGGGATAGATATTAACGAAATCCCTGCCTATGTAGAATAA

Upstream 100 bases:

>100_bases
ATTTTGAACGAGTCTGATATGTAAACGCAACCAAATTTTGTTGTGTGATTTTTTATATGCATGTATAATTTGAATAAGTC
TGAAAAAAGGGGGAGTTTTT

Downstream 100 bases:

>100_bases
TATATATAAAAGGTGATCGAGAGTTACTCCCGATCACCTTTTATATAGCAGTTTTTTTATTTTCGCGCTTTTGATCAACA
CGAAATTGTACATATTGTTT

Product: sodium-dependent transporter

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MLHATWYWMWEKHDQVKDLFRLFVNPNEIIEKNKKDSTPSSTTSNSNNGDDGGNNRQYNKAQLIGLFLGPISFILTLLFF
SPEGLSSEGQAVLASTIWIAIWWMTEAIPIPATALLPIILFPLTNGLDIGATTSAYGSDTIFLFMGGFVIALAMERWNLH
RRIAISIISVIGTNTDRIILGFMVATGFLSMFISNTATAMMMVPIGLAIIYQVSDTLKEQGGFDTSPENFSFGKSLMLGI
AYSASIGGMATLIGTPPNVIFAGTINTMYGIEVSFASWMMFGVPFAWIFIFLTWFYLSKIAFKLEVSHIPGGAKIIKEEK
KKLGNASYEEKAVFVVFILAAIAWISREFLLGPYVSENINDAIIAITAALVLFLIPAKNKKGDFLMNWESAIKLPWGILL
LFGGGLAIAAGFTDSGLSDWIGEQLTGLENVAPIIIILSIAALVIFLTEITSNTATATMMFPIMAALAVAVGVHPFILMI
AAALAASCAFMLPVATPPNAVVFGSGYLRIPDMAKAGFFLNIVGIILVTLTVYFLVPMALGIDINEIPAYVE

Sequences:

>Translated_552_residues
MLHATWYWMWEKHDQVKDLFRLFVNPNEIIEKNKKDSTPSSTTSNSNNGDDGGNNRQYNKAQLIGLFLGPISFILTLLFF
SPEGLSSEGQAVLASTIWIAIWWMTEAIPIPATALLPIILFPLTNGLDIGATTSAYGSDTIFLFMGGFVIALAMERWNLH
RRIAISIISVIGTNTDRIILGFMVATGFLSMFISNTATAMMMVPIGLAIIYQVSDTLKEQGGFDTSPENFSFGKSLMLGI
AYSASIGGMATLIGTPPNVIFAGTINTMYGIEVSFASWMMFGVPFAWIFIFLTWFYLSKIAFKLEVSHIPGGAKIIKEEK
KKLGNASYEEKAVFVVFILAAIAWISREFLLGPYVSENINDAIIAITAALVLFLIPAKNKKGDFLMNWESAIKLPWGILL
LFGGGLAIAAGFTDSGLSDWIGEQLTGLENVAPIIIILSIAALVIFLTEITSNTATATMMFPIMAALAVAVGVHPFILMI
AAALAASCAFMLPVATPPNAVVFGSGYLRIPDMAKAGFFLNIVGIILVTLTVYFLVPMALGIDINEIPAYVE
>Mature_552_residues
MLHATWYWMWEKHDQVKDLFRLFVNPNEIIEKNKKDSTPSSTTSNSNNGDDGGNNRQYNKAQLIGLFLGPISFILTLLFF
SPEGLSSEGQAVLASTIWIAIWWMTEAIPIPATALLPIILFPLTNGLDIGATTSAYGSDTIFLFMGGFVIALAMERWNLH
RRIAISIISVIGTNTDRIILGFMVATGFLSMFISNTATAMMMVPIGLAIIYQVSDTLKEQGGFDTSPENFSFGKSLMLGI
AYSASIGGMATLIGTPPNVIFAGTINTMYGIEVSFASWMMFGVPFAWIFIFLTWFYLSKIAFKLEVSHIPGGAKIIKEEK
KKLGNASYEEKAVFVVFILAAIAWISREFLLGPYVSENINDAIIAITAALVLFLIPAKNKKGDFLMNWESAIKLPWGILL
LFGGGLAIAAGFTDSGLSDWIGEQLTGLENVAPIIIILSIAALVIFLTEITSNTATATMMFPIMAALAVAVGVHPFILMI
AAALAASCAFMLPVATPPNAVVFGSGYLRIPDMAKAGFFLNIVGIILVTLTVYFLVPMALGIDINEIPAYVE

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=502, Percent_Identity=39.0438247011952, Blast_Score=307, Evalue=2e-83,
Organism=Homo sapiens, GI31377715, Length=560, Percent_Identity=33.9285714285714, Blast_Score=303, Evalue=2e-82,
Organism=Homo sapiens, GI58761541, Length=516, Percent_Identity=35.6589147286822, Blast_Score=301, Evalue=1e-81,
Organism=Homo sapiens, GI4506979, Length=513, Percent_Identity=36.0623781676413, Blast_Score=296, Evalue=3e-80,
Organism=Homo sapiens, GI301069349, Length=498, Percent_Identity=35.9437751004016, Blast_Score=283, Evalue=3e-76,
Organism=Homo sapiens, GI225637549, Length=564, Percent_Identity=34.2198581560284, Blast_Score=276, Evalue=3e-74,
Organism=Homo sapiens, GI301069346, Length=512, Percent_Identity=33.3984375, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI225637552, Length=474, Percent_Identity=35.6540084388186, Blast_Score=266, Evalue=3e-71,
Organism=Homo sapiens, GI301069353, Length=465, Percent_Identity=34.6236559139785, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI219802232, Length=443, Percent_Identity=37.6975169300226, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI19923838, Length=351, Percent_Identity=38.4615384615385, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI31795546, Length=335, Percent_Identity=34.6268656716418, Blast_Score=186, Evalue=4e-47,
Organism=Escherichia coli, GI1786829, Length=410, Percent_Identity=24.6341463414634, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789444, Length=424, Percent_Identity=20.9905660377358, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71988385, Length=515, Percent_Identity=35.3398058252427, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI32565804, Length=482, Percent_Identity=35.4771784232365, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI71989118, Length=520, Percent_Identity=33.4615384615385, Blast_Score=254, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI32564681, Length=522, Percent_Identity=31.2260536398467, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17551790, Length=503, Percent_Identity=30.2186878727634, Blast_Score=217, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6324340, Length=453, Percent_Identity=26.7108167770419, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6322263, Length=532, Percent_Identity=24.2481203007519, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319885, Length=428, Percent_Identity=26.6355140186916, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281366409, Length=472, Percent_Identity=33.0508474576271, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI17737623, Length=472, Percent_Identity=33.0508474576271, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24666468, Length=472, Percent_Identity=33.0508474576271, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI45551633, Length=472, Percent_Identity=33.0508474576271, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI281362116, Length=472, Percent_Identity=33.0508474576271, Blast_Score=218, Evalue=7e-57,
Organism=Drosophila melanogaster, GI281362114, Length=472, Percent_Identity=32.8389830508475, Blast_Score=211, Evalue=8e-55,
Organism=Drosophila melanogaster, GI281362112, Length=472, Percent_Identity=32.8389830508475, Blast_Score=211, Evalue=8e-55,
Organism=Drosophila melanogaster, GI78706796, Length=475, Percent_Identity=29.0526315789474, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI78706798, Length=475, Percent_Identity=29.0526315789474, Blast_Score=150, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 59895; Mature: 59895

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS01271 NA_SULFATE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHATWYWMWEKHDQVKDLFRLFVNPNEIIEKNKKDSTPSSTTSNSNNGDDGGNNRQYNK
CCEEEEEEEECCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
AQLIGLFLGPISFILTLLFFSPEGLSSEGQAVLASTIWIAIWWMTEAIPIPATALLPIIL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
FPLTNGLDIGATTSAYGSDTIFLFMGGFVIALAMERWNLHRRIAISIISVIGTNTDRIIL
HHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHH
GFMVATGFLSMFISNTATAMMMVPIGLAIIYQVSDTLKEQGGFDTSPENFSFGKSLMLGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
AYSASIGGMATLIGTPPNVIFAGTINTMYGIEVSFASWMMFGVPFAWIFIFLTWFYLSKI
HHHCCCCCEEEEECCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFKLEVSHIPGGAKIIKEEKKKLGNASYEEKAVFVVFILAAIAWISREFLLGPYVSENIN
HEEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DAIIAITAALVLFLIPAKNKKGDFLMNWESAIKLPWGILLLFGGGLAIAAGFTDSGLSDW
HHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHCCCHHHHHEECCCEEEEECCCCCCHHHH
IGEQLTGLENVAPIIIILSIAALVIFLTEITSNTATATMMFPIMAALAVAVGVHPFILMI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AAALAASCAFMLPVATPPNAVVFGSGYLRIPDMAKAGFFLNIVGIILVTLTVYFLVPMAL
HHHHHHHHHHEEECCCCCCEEEECCCCEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
GIDINEIPAYVE
CCCHHHCCCCCC
>Mature Secondary Structure
MLHATWYWMWEKHDQVKDLFRLFVNPNEIIEKNKKDSTPSSTTSNSNNGDDGGNNRQYNK
CCEEEEEEEECCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
AQLIGLFLGPISFILTLLFFSPEGLSSEGQAVLASTIWIAIWWMTEAIPIPATALLPIIL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
FPLTNGLDIGATTSAYGSDTIFLFMGGFVIALAMERWNLHRRIAISIISVIGTNTDRIIL
HHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHH
GFMVATGFLSMFISNTATAMMMVPIGLAIIYQVSDTLKEQGGFDTSPENFSFGKSLMLGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
AYSASIGGMATLIGTPPNVIFAGTINTMYGIEVSFASWMMFGVPFAWIFIFLTWFYLSKI
HHHCCCCCEEEEECCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFKLEVSHIPGGAKIIKEEKKKLGNASYEEKAVFVVFILAAIAWISREFLLGPYVSENIN
HEEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DAIIAITAALVLFLIPAKNKKGDFLMNWESAIKLPWGILLLFGGGLAIAAGFTDSGLSDW
HHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHCCCHHHHHEECCCEEEEECCCCCCHHHH
IGEQLTGLENVAPIIIILSIAALVIFLTEITSNTATATMMFPIMAALAVAVGVHPFILMI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AAALAASCAFMLPVATPPNAVVFGSGYLRIPDMAKAGFFLNIVGIILVTLTVYFLVPMAL
HHHHHHHHHHEEECCCCCCEEEECCCCEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
GIDINEIPAYVE
CCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA