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The map label for this gene is pbpC [H]

Identifier: 23099986

GI number: 23099986

Start: 2585716

End: 2587728

Strand: Direct

Name: pbpC [H]

Synonym: OB2531

Alternate gene names: 23099986

Gene position: 2585716-2587728 (Clockwise)

Preceding gene: 23099985

Following gene: 23099995

Centisome position: 71.22

GC content: 36.61

Gene sequence:

>2013_bases
ATGTTTAAAAGATTATTAATGTTTGGAGTAATGATTTTTATATTATCGGCTTGCTCCGATGATCAAGTTACACCAAATGA
AAGGTTAGAAGATTTTACAAGTAAGATGCAAGAACAAACGTATGAAGGCTTGTATGATTATCTAACTCCAGAAGCTCAGG
ATACATATTCAGAAGAGGATTCAACGTTACGTACAGAAAATATTTATACAGATTTAAATGTAACCGATTTAACATTCGAA
ATTGAATCATTAGGTGAGGATGCCTTAAATAAAGCTTTTGAAGAAAAATCAGCATCTGTACCTTTTAAGGTTTCAATGGA
AACAATGGCTGGGCCGGTTGAATTTGATTATGAAGCAAATTTAAAACTTCTTGGTGAAGAAGACGAAGAAAATTGGTATA
TCGATTGGAATCCTGGTTTTATTTTCCCAGAACTAGCAGATGGCGGGGATTTAGGGATTTCTTCAACTCTTCCTAAGCGC
GGCGAGATATTAGACCGTAATAATATTCCCTTAGCGATGAATGGAGAACTATATGAAATCGGTTTGGTTCCAGGTGAACT
TGGGGAAAGTGCAGAAGAGAACAAGGAAAACGTAGCTGATTTACTTGGTCTTTCAGTTGAACATATTAATGAAACATTAA
ATGCCTCTTGGGTTACCGATGATGTGTTCGTCCCATTAGCAACCATTATGACAGACAAAGAAGAGCTTTTTCAAGATTTA
ATGGCAATTGATGGAGTAACTTACCGAGAAATCACTGGAAGAATTTATCCAGGAGAAGAAGCTAGTGCACATTTAGTTGG
TTATATACGGGATGTAACTGCAGAAGACCTAGAAGAATTAGATCCGGGTGAATACAGTGCCAATGATAAAATTGGATCAC
GCGGTTTGGAAAGTCTATACGAAGAAAAATTGCGTGGTAAGAAAGGTACTACTATATATGTAGAACAAGATGGGCAGGAC
AACACTATAATTGCAGAAAAACCTGTTGAGAATGGAGAAAATGTTCAAGTCACGATTGATATAAATGTACAAGAAAAAAT
ATTTGATCAATTTAATGGCAATCCAGGTAATGCTACAGCAATAAATCCCTCCACTGGAGAGACAATGGCATTAGTTAGCA
GTCCATCTTTTGATCCAAATGAAGCACTATATGGAACTTCTGAAAATTTCTGGGGTGATCTAGAAGAAAACGAGCTTAAT
CCTGTATTAAATCGATTTTCTGCGACTTTCGCTCCTGGGTCTGTGATAAAGCCTGTAACTGCAGCAATAGGGTTAGACAA
CGGATCGATTTCCTATGGTGATGGAATTGAAATAAACGGATTGAAATGGAGTAATGGCGAAAATTGGGGTGACTATGAAG
TTACTCGTGTATCCACTTCTAACGTTCCTGTAGATGTCGACGATGCATTAATAAGGTCTGATAATATTTTCTTTGCGATG
AAAGCAGTAGAAATGGGTGCAGATGCTTATGTTGATGGTCTTCATTCTTTTGGAATAGGTGAAGAATTTCCTTATGAGTA
TCCCGTTCCTGATTCAACAGTATCATCGAGTGGAGATTTAAACGATGAAGTTTTATTAGCCAACTCAAGTTATGGTCAGG
GCGAACTTGAAATGAGTGCTATTCATCTTGCATCTACGTATACAACTTTTCTTAACAATGGTAACATGCTAAAACCAACT
TTATTAATCGATGAAGAAAATAGTCAAGTATGGAAAGAAAACTTAGTAACAGAAGAACAAGCAAATGACATAAAAGATTC
GCTTCGTAAAGTAGTCACAGAAGGCACAGGTAAAGCTGCCCAAGAAGCTAACTTACCTATCTCTGGTAAAACAGGTACAG
CGGAATTAAAGCTCACAAGTGAAGATAGCGGTGACGAAAATAGTTGGTTTGTTGGATATCCAACCGAAGAACAAGATGTT
TTACTATCTTTAATGATAGAAGGAACTAAAAATCATGACAGACCATCTGCTGTAGAAGTAGCTACCGAAATATTTATAAA
GCTATATGAATAA

Upstream 100 bases:

>100_bases
GTGACTTTTTCTTTTATGCTCATCAGAGGGAGTTTGATACATCTATTGACGTAGAAAAAATGCTATACTTAAAATGAGTA
GATTTTATGGGGGTCTAATT

Downstream 100 bases:

>100_bases
GAACAAAAGCGCAAGCGCTCGTTTATCACCGTATGTCCTGCGCCCCTGTTTTTGAAGGGGTGGTTCGACTGGTCGAGCTT
CTTTATTTCTTTGAGATAAA

Product: penicillin-binding protein 3

Products: NA

Alternate protein names: PBP 3; PSPB20; Penicillin-binding protein C [H]

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MFKRLLMFGVMIFILSACSDDQVTPNERLEDFTSKMQEQTYEGLYDYLTPEAQDTYSEEDSTLRTENIYTDLNVTDLTFE
IESLGEDALNKAFEEKSASVPFKVSMETMAGPVEFDYEANLKLLGEEDEENWYIDWNPGFIFPELADGGDLGISSTLPKR
GEILDRNNIPLAMNGELYEIGLVPGELGESAEENKENVADLLGLSVEHINETLNASWVTDDVFVPLATIMTDKEELFQDL
MAIDGVTYREITGRIYPGEEASAHLVGYIRDVTAEDLEELDPGEYSANDKIGSRGLESLYEEKLRGKKGTTIYVEQDGQD
NTIIAEKPVENGENVQVTIDINVQEKIFDQFNGNPGNATAINPSTGETMALVSSPSFDPNEALYGTSENFWGDLEENELN
PVLNRFSATFAPGSVIKPVTAAIGLDNGSISYGDGIEINGLKWSNGENWGDYEVTRVSTSNVPVDVDDALIRSDNIFFAM
KAVEMGADAYVDGLHSFGIGEEFPYEYPVPDSTVSSSGDLNDEVLLANSSYGQGELEMSAIHLASTYTTFLNNGNMLKPT
LLIDEENSQVWKENLVTEEQANDIKDSLRKVVTEGTGKAAQEANLPISGKTGTAELKLTSEDSGDENSWFVGYPTEEQDV
LLSLMIEGTKNHDRPSAVEVATEIFIKLYE

Sequences:

>Translated_670_residues
MFKRLLMFGVMIFILSACSDDQVTPNERLEDFTSKMQEQTYEGLYDYLTPEAQDTYSEEDSTLRTENIYTDLNVTDLTFE
IESLGEDALNKAFEEKSASVPFKVSMETMAGPVEFDYEANLKLLGEEDEENWYIDWNPGFIFPELADGGDLGISSTLPKR
GEILDRNNIPLAMNGELYEIGLVPGELGESAEENKENVADLLGLSVEHINETLNASWVTDDVFVPLATIMTDKEELFQDL
MAIDGVTYREITGRIYPGEEASAHLVGYIRDVTAEDLEELDPGEYSANDKIGSRGLESLYEEKLRGKKGTTIYVEQDGQD
NTIIAEKPVENGENVQVTIDINVQEKIFDQFNGNPGNATAINPSTGETMALVSSPSFDPNEALYGTSENFWGDLEENELN
PVLNRFSATFAPGSVIKPVTAAIGLDNGSISYGDGIEINGLKWSNGENWGDYEVTRVSTSNVPVDVDDALIRSDNIFFAM
KAVEMGADAYVDGLHSFGIGEEFPYEYPVPDSTVSSSGDLNDEVLLANSSYGQGELEMSAIHLASTYTTFLNNGNMLKPT
LLIDEENSQVWKENLVTEEQANDIKDSLRKVVTEGTGKAAQEANLPISGKTGTAELKLTSEDSGDENSWFVGYPTEEQDV
LLSLMIEGTKNHDRPSAVEVATEIFIKLYE
>Mature_670_residues
MFKRLLMFGVMIFILSACSDDQVTPNERLEDFTSKMQEQTYEGLYDYLTPEAQDTYSEEDSTLRTENIYTDLNVTDLTFE
IESLGEDALNKAFEEKSASVPFKVSMETMAGPVEFDYEANLKLLGEEDEENWYIDWNPGFIFPELADGGDLGISSTLPKR
GEILDRNNIPLAMNGELYEIGLVPGELGESAEENKENVADLLGLSVEHINETLNASWVTDDVFVPLATIMTDKEELFQDL
MAIDGVTYREITGRIYPGEEASAHLVGYIRDVTAEDLEELDPGEYSANDKIGSRGLESLYEEKLRGKKGTTIYVEQDGQD
NTIIAEKPVENGENVQVTIDINVQEKIFDQFNGNPGNATAINPSTGETMALVSSPSFDPNEALYGTSENFWGDLEENELN
PVLNRFSATFAPGSVIKPVTAAIGLDNGSISYGDGIEINGLKWSNGENWGDYEVTRVSTSNVPVDVDDALIRSDNIFFAM
KAVEMGADAYVDGLHSFGIGEEFPYEYPVPDSTVSSSGDLNDEVLLANSSYGQGELEMSAIHLASTYTTFLNNGNMLKPT
LLIDEENSQVWKENLVTEEQANDIKDSLRKVVTEGTGKAAQEANLPISGKTGTAELKLTSEDSGDENSWFVGYPTEEQDV
LLSLMIEGTKNHDRPSAVEVATEIFIKLYE

Specific function: Cell Wall Formation; Pbp-2 Is Responsible For The Determination Of The Rod Shape Of The Cell. Its Synthesize Cross- Linked Peptidoglycan From The Lipid Intermediates. [C]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=506, Percent_Identity=25.296442687747, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1786272, Length=500, Percent_Identity=24.6, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR007887
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF05223 MecA_N; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 73912; Mature: 73912

Theoretical pI: Translated: 3.78; Mature: 3.78

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKRLLMFGVMIFILSACSDDQVTPNERLEDFTSKMQEQTYEGLYDYLTPEAQDTYSEED
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCC
STLRTENIYTDLNVTDLTFEIESLGEDALNKAFEEKSASVPFKVSMETMAGPVEFDYEAN
CCEEECCEEECCCEEEEEEEHHHCCHHHHHHHHHHHCCCCCEEEEHHHCCCCEEECCCCC
LKLLGEEDEENWYIDWNPGFIFPELADGGDLGISSTLPKRGEILDRNNIPLAMNGELYEI
EEEECCCCCCCEEEECCCCEEECCCCCCCCCCCCCCCCCCCCEECCCCCCEEECCCEEEE
GLVPGELGESAEENKENVADLLGLSVEHINETLNASWVTDDVFVPLATIMTDKEELFQDL
ECCCCHHCCCHHHHHHHHHHHHCCCHHHHHHHCCCCEECCHHHHHHHHHHCCHHHHHHHH
MAIDGVTYREITGRIYPGEEASAHLVGYIRDVTAEDLEELDPGEYSANDKIGSRGLESLY
HHHCCCEEEHHCCEECCCCCCCHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHH
EEKLRGKKGTTIYVEQDGQDNTIIAEKPVENGENVQVTIDINVQEKIFDQFNGNPGNATA
HHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCEEEEEEEECHHHHHHHHHCCCCCCCEE
INPSTGETMALVSSPSFDPNEALYGTSENFWGDLEENELNPVLNRFSATFAPGSVIKPVT
ECCCCCCEEEEEECCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHCHHH
AAIGLDNGSISYGDGIEINGLKWSNGENWGDYEVTRVSTSNVPVDVDDALIRSDNIFFAM
HEEECCCCCEECCCCEEECCEEECCCCCCCCEEEEEEECCCCCCCCCHHHEECCCEEEEE
KAVEMGADAYVDGLHSFGIGEEFPYEYPVPDSTVSSSGDLNDEVLLANSSYGQGELEMSA
EEHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEE
IHLASTYTTFLNNGNMLKPTLLIDEENSQVWKENLVTEEQANDIKDSLRKVVTEGTGKAA
EEHHHHHHHHHCCCCEECEEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCH
QEANLPISGKTGTAELKLTSEDSGDENSWFVGYPTEEQDVLLSLMIEGTKNHDRPSAVEV
HHCCCCCCCCCCCEEEEEECCCCCCCCCEEEECCCCHHHEEEEEEEECCCCCCCCHHHHH
ATEIFIKLYE
HHHHHHEECC
>Mature Secondary Structure
MFKRLLMFGVMIFILSACSDDQVTPNERLEDFTSKMQEQTYEGLYDYLTPEAQDTYSEED
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCC
STLRTENIYTDLNVTDLTFEIESLGEDALNKAFEEKSASVPFKVSMETMAGPVEFDYEAN
CCEEECCEEECCCEEEEEEEHHHCCHHHHHHHHHHHCCCCCEEEEHHHCCCCEEECCCCC
LKLLGEEDEENWYIDWNPGFIFPELADGGDLGISSTLPKRGEILDRNNIPLAMNGELYEI
EEEECCCCCCCEEEECCCCEEECCCCCCCCCCCCCCCCCCCCEECCCCCCEEECCCEEEE
GLVPGELGESAEENKENVADLLGLSVEHINETLNASWVTDDVFVPLATIMTDKEELFQDL
ECCCCHHCCCHHHHHHHHHHHHCCCHHHHHHHCCCCEECCHHHHHHHHHHCCHHHHHHHH
MAIDGVTYREITGRIYPGEEASAHLVGYIRDVTAEDLEELDPGEYSANDKIGSRGLESLY
HHHCCCEEEHHCCEECCCCCCCHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHH
EEKLRGKKGTTIYVEQDGQDNTIIAEKPVENGENVQVTIDINVQEKIFDQFNGNPGNATA
HHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCEEEEEEEECHHHHHHHHHCCCCCCCEE
INPSTGETMALVSSPSFDPNEALYGTSENFWGDLEENELNPVLNRFSATFAPGSVIKPVT
ECCCCCCEEEEEECCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHCHHH
AAIGLDNGSISYGDGIEINGLKWSNGENWGDYEVTRVSTSNVPVDVDDALIRSDNIFFAM
HEEECCCCCEECCCCEEECCEEECCCCCCCCEEEEEEECCCCCCCCCHHHEECCCEEEEE
KAVEMGADAYVDGLHSFGIGEEFPYEYPVPDSTVSSSGDLNDEVLLANSSYGQGELEMSA
EEHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEE
IHLASTYTTFLNNGNMLKPTLLIDEENSQVWKENLVTEEQANDIKDSLRKVVTEGTGKAA
EEHHHHHHHHHCCCCEECEEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCH
QEANLPISGKTGTAELKLTSEDSGDENSWFVGYPTEEQDVLLSLMIEGTKNHDRPSAVEV
HHCCCCCCCCCCCEEEEEECCCCCCCCCEEEECCCCHHHEEEEEEEECCCCCCCCHHHHH
ATEIFIKLYE
HHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 3145906 [H]