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The map label for this gene is pgi

Identifier: 23099791

GI number: 23099791

Start: 2390988

End: 2392334

Strand: Direct

Name: pgi

Synonym: OB2336

Alternate gene names: 23099791

Gene position: 2390988-2392334 (Clockwise)

Preceding gene: 23099790

Following gene: 23099793

Centisome position: 65.86

GC content: 36.15

Gene sequence:

>1347_bases
TTGACACATGTATCCTTTAACTACGAAAAGGCATTGTCATTTTTCGAAAAACAAGAAATTACAAATCTAGAACCGTTTGT
TCATACTGCGCATCAAATGATTCATGAACGTATTGGAGCAGGTAAAGATTTCTTGGGTTGGCTTGACTTACCTAGAAATT
ATAACCGTGAAGAATATACACGAATAAAAGCTGCTGCTGATAAAATAAAAAAAGACTCCGATATTTTACTTGTTATTGGC
ATAGGCGGATCTTATTTAGGTGCCAAAGCAGCACTTGAGATGTTGAATCATTCTTTCCAAAACCTTCTATCTAAGGATCA
ACGTCAAGTTCCACAAATTATTTTTGTCGGTCATCATTTAAGTTCAACTTATATGACTGAGCTTTTCGATATTCTTAAAG
ACAAAGATTTCTCTATCAACGTAATTTCTAAAAGTGGAACGACTACGGAGCCTGCAATTGCGTTTCGTGTTTTCAAGAAG
TATCTTGAAGAAAAATATGGACAAGACGAGGCGAAAAAACGCATTTATGCAACAACTGACCGTTCTAAAGGAGCATTAAA
AACTACTGCAGATTCCAATGACTATGAAACATTTGTTATTCCTGATGATGTAGGTGGACGATACTCAGTATTAACAGCAG
TTGGGTTACTTCCAATCGCTGCCAGCGGCATTAATATCGATGACATGATGGAAGGCGCAAAAGCTGGAATGGAAGACCTT
GCTAATCCAGTCATATCTGAAAATCCAGCATACCAGTATGCGGCTGTAAGAAATATTCTCTATCAAAAAGGGAAAGTTAC
TGAGTTATTAATTAACTATGAGCCGAATTTACAATACTTCTCTGAATGGTGGAAACAATTATTTGGGGAAAGTGAAGGAA
AAAATCAAAAGGGAATTTATCCTTCATCAGCGAATTTCACTACAGACTTGCACTCTCTTGGACAATACATTCAAGAAGGT
CGTCGTAATATATTCGAAACTATCCTACACGTGAATGAACCGAAAAAAGATTTCACATTAGAGAAAGAAGAATCGGATTT
AGATGGCTTAAATTACTTAGCTGGTAAGTCGATTCATGAGATTAATGATAAAGCTTTCCAAGGAACACTGCTTGCACATA
CAGATGGAGATGTACCAAACTTAATCGTAGAAGTTCCTAGATTAGATGCATATACGTTTGGTTACCTTGTTTATTTCTTT
GAAAAAGCATGTGCAATAAGTGGATATATTCTTGGTGTTAATCCGTTTGATCAACCTGGGGTTGAGGCATATAAAAAGAA
TATGTTTGCCCTACTCGGAAAACCAGGATTCGAAGATCAAAAAGAAGCGTTAGAAAAACGTTTGTAA

Upstream 100 bases:

>100_bases
GAGTCTTTTTCATTTGTAAAGGGCTTGTTCTTGATTTCACATACCGTATCGCTTAAAGTTAAATTATAGAAATAATTGCT
TTTACAGAGGAGGAAATAAC

Downstream 100 bases:

>100_bases
TAAAGAAAAGCGAAAGCGCCCCTGTGTTTAAGGCGTGATTCAAAAAAGGTCGATAAAGAGGCTCTTAAGATGGAGCCTCT
TTTGTTTTTGTTCTATCATA

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MTHVSFNYEKALSFFEKQEITNLEPFVHTAHQMIHERIGAGKDFLGWLDLPRNYNREEYTRIKAAADKIKKDSDILLVIG
IGGSYLGAKAALEMLNHSFQNLLSKDQRQVPQIIFVGHHLSSTYMTELFDILKDKDFSINVISKSGTTTEPAIAFRVFKK
YLEEKYGQDEAKKRIYATTDRSKGALKTTADSNDYETFVIPDDVGGRYSVLTAVGLLPIAASGINIDDMMEGAKAGMEDL
ANPVISENPAYQYAAVRNILYQKGKVTELLINYEPNLQYFSEWWKQLFGESEGKNQKGIYPSSANFTTDLHSLGQYIQEG
RRNIFETILHVNEPKKDFTLEKEESDLDGLNYLAGKSIHEINDKAFQGTLLAHTDGDVPNLIVEVPRLDAYTFGYLVYFF
EKACAISGYILGVNPFDQPGVEAYKKNMFALLGKPGFEDQKEALEKRL

Sequences:

>Translated_448_residues
MTHVSFNYEKALSFFEKQEITNLEPFVHTAHQMIHERIGAGKDFLGWLDLPRNYNREEYTRIKAAADKIKKDSDILLVIG
IGGSYLGAKAALEMLNHSFQNLLSKDQRQVPQIIFVGHHLSSTYMTELFDILKDKDFSINVISKSGTTTEPAIAFRVFKK
YLEEKYGQDEAKKRIYATTDRSKGALKTTADSNDYETFVIPDDVGGRYSVLTAVGLLPIAASGINIDDMMEGAKAGMEDL
ANPVISENPAYQYAAVRNILYQKGKVTELLINYEPNLQYFSEWWKQLFGESEGKNQKGIYPSSANFTTDLHSLGQYIQEG
RRNIFETILHVNEPKKDFTLEKEESDLDGLNYLAGKSIHEINDKAFQGTLLAHTDGDVPNLIVEVPRLDAYTFGYLVYFF
EKACAISGYILGVNPFDQPGVEAYKKNMFALLGKPGFEDQKEALEKRL
>Mature_447_residues
THVSFNYEKALSFFEKQEITNLEPFVHTAHQMIHERIGAGKDFLGWLDLPRNYNREEYTRIKAAADKIKKDSDILLVIGI
GGSYLGAKAALEMLNHSFQNLLSKDQRQVPQIIFVGHHLSSTYMTELFDILKDKDFSINVISKSGTTTEPAIAFRVFKKY
LEEKYGQDEAKKRIYATTDRSKGALKTTADSNDYETFVIPDDVGGRYSVLTAVGLLPIAASGINIDDMMEGAKAGMEDLA
NPVISENPAYQYAAVRNILYQKGKVTELLINYEPNLQYFSEWWKQLFGESEGKNQKGIYPSSANFTTDLHSLGQYIQEGR
RNIFETILHVNEPKKDFTLEKEESDLDGLNYLAGKSIHEINDKAFQGTLLAHTDGDVPNLIVEVPRLDAYTFGYLVYFFE
KACAISGYILGVNPFDQPGVEAYKKNMFALLGKPGFEDQKEALEKRL

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G6PI_OCEIH (Q8ENY8)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693257.1
- ProteinModelPortal:   Q8ENY8
- SMR:   Q8ENY8
- GeneID:   1017298
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2336
- NMPDR:   fig|221109.1.peg.2333
- HOGENOM:   HBG615843
- OMA:   YVNDRAY
- ProtClustDB:   PRK14097
- BioCyc:   OIHE221109:OB2336-MONOMER
- BRENDA:   5.3.1.9
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_00473
- InterPro:   IPR001672
- InterPro:   IPR018189
- PANTHER:   PTHR11469
- PRINTS:   PR00662

Pfam domain/function: PF00342 PGI

EC number: =5.3.1.9

Molecular weight: Translated: 50593; Mature: 50462

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1; PS00174 P_GLUCOSE_ISOMERASE_2; PS51463 P_GLUCOSE_ISOMERASE_3

Important sites: ACT_SITE 290-290 ACT_SITE 311-311 ACT_SITE 425-425

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHVSFNYEKALSFFEKQEITNLEPFVHTAHQMIHERIGAGKDFLGWLDLPRNYNREEYT
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHH
RIKAAADKIKKDSDILLVIGIGGSYLGAKAALEMLNHSFQNLLSKDQRQVPQIIFVGHHL
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCH
SSTYMTELFDILKDKDFSINVISKSGTTTEPAIAFRVFKKYLEEKYGQDEAKKRIYATTD
HHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCEEEECC
RSKGALKTTADSNDYETFVIPDDVGGRYSVLTAVGLLPIAASGINIDDMMEGAKAGMEDL
CCCCCEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHH
ANPVISENPAYQYAAVRNILYQKGKVTELLINYEPNLQYFSEWWKQLFGESEGKNQKGIY
CCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCC
PSSANFTTDLHSLGQYIQEGRRNIFETILHVNEPKKDFTLEKEESDLDGLNYLAGKSIHE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCHHH
INDKAFQGTLLAHTDGDVPNLIVEVPRLDAYTFGYLVYFFEKACAISGYILGVNPFDQPG
HCCHHHCCEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
VEAYKKNMFALLGKPGFEDQKEALEKRL
HHHHHHHHHHHHCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
THVSFNYEKALSFFEKQEITNLEPFVHTAHQMIHERIGAGKDFLGWLDLPRNYNREEYT
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHH
RIKAAADKIKKDSDILLVIGIGGSYLGAKAALEMLNHSFQNLLSKDQRQVPQIIFVGHHL
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCH
SSTYMTELFDILKDKDFSINVISKSGTTTEPAIAFRVFKKYLEEKYGQDEAKKRIYATTD
HHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCEEEECC
RSKGALKTTADSNDYETFVIPDDVGGRYSVLTAVGLLPIAASGINIDDMMEGAKAGMEDL
CCCCCEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHH
ANPVISENPAYQYAAVRNILYQKGKVTELLINYEPNLQYFSEWWKQLFGESEGKNQKGIY
CCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCC
PSSANFTTDLHSLGQYIQEGRRNIFETILHVNEPKKDFTLEKEESDLDGLNYLAGKSIHE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCHHH
INDKAFQGTLLAHTDGDVPNLIVEVPRLDAYTFGYLVYFFEKACAISGYILGVNPFDQPG
HCCHHHCCEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
VEAYKKNMFALLGKPGFEDQKEALEKRL
HHHHHHHHHHHHCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376