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The map label for this gene is udk

Identifier: 23099458

GI number: 23099458

Start: 2027131

End: 2027763

Strand: Reverse

Name: udk

Synonym: OB2003

Alternate gene names: 23099458

Gene position: 2027763-2027131 (Counterclockwise)

Preceding gene: 23099459

Following gene: 23099457

Centisome position: 55.85

GC content: 33.65

Gene sequence:

>633_bases
ATGACAAAGCAAAAACCAGTTGTAATTGGAGTAGCAGGAGGAAGTGGATCAGGAAAAACATCTGTGACTCGCTCCATTTG
TCAACGATTTACAGAAACATCGATTTTGGTAATCGAGCAGGATTATTATTATAAAGATCAAAGTCACTTACCATTCGAGG
AAAGATTAAATACCAATTATGATCATCCATTGGCGTTTGATAATGATTTATTAATAGAACATTTACAGCAATTAATGCAT
AATGAACCAATTGAAAAACCTGTATATGATTATAAAATTCATACTCGGTCAAAAGACGTTATTCATGTAGAACCAAAAGA
AGTTATTATTGTAGAAGGTATATTAATACTTGAAGATCCACGCTTAGTTGATTTAATGGATATTAAGGTTTATGTTGATA
CGGATGCAGATTTACGAATAATTCGCCGCTTAATGCGAGATATCAAAGAGCGCGGTAGGACGTTAGATTCTGTAATCGAT
CAATATATCCAGAATGTTCGCCCATCACACCTGCAATTTATTGAACCAACAAAGCGTTATGCCGATATAATCATACCTGA
AGGTGGACAAAATCATGTCGCAATTGATATCATGGCTTCTAAAATAGAAAAAATATTATCTAGAGGGTTATAA

Upstream 100 bases:

>100_bases
ACTAATGAACCATCCACATTATCAAACATCGATCTTACCAATTGGTGATGGTGTAGCAATTAGTTATAAGCTAGAAGAAG
GAAATTAGGAGGAGCAAGGC

Downstream 100 bases:

>100_bases
TTAACGGTAAGAAATATTGAAAATTAATAATAAATCTGCCATAGTAGTCTTTAGTATATTGTAAATGTTTCCAGCATAAG
TTGTAAGACTTATTTATTTG

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MTKQKPVVIGVAGGSGSGKTSVTRSICQRFTETSILVIEQDYYYKDQSHLPFEERLNTNYDHPLAFDNDLLIEHLQQLMH
NEPIEKPVYDYKIHTRSKDVIHVEPKEVIIVEGILILEDPRLVDLMDIKVYVDTDADLRIIRRLMRDIKERGRTLDSVID
QYIQNVRPSHLQFIEPTKRYADIIIPEGGQNHVAIDIMASKIEKILSRGL

Sequences:

>Translated_210_residues
MTKQKPVVIGVAGGSGSGKTSVTRSICQRFTETSILVIEQDYYYKDQSHLPFEERLNTNYDHPLAFDNDLLIEHLQQLMH
NEPIEKPVYDYKIHTRSKDVIHVEPKEVIIVEGILILEDPRLVDLMDIKVYVDTDADLRIIRRLMRDIKERGRTLDSVID
QYIQNVRPSHLQFIEPTKRYADIIIPEGGQNHVAIDIMASKIEKILSRGL
>Mature_209_residues
TKQKPVVIGVAGGSGSGKTSVTRSICQRFTETSILVIEQDYYYKDQSHLPFEERLNTNYDHPLAFDNDLLIEHLQQLMHN
EPIEKPVYDYKIHTRSKDVIHVEPKEVIIVEGILILEDPRLVDLMDIKVYVDTDADLRIIRRLMRDIKERGRTLDSVIDQ
YIQNVRPSHLQFIEPTKRYADIIIPEGGQNHVAIDIMASKIEKILSRGL

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family

Homologues:

Organism=Homo sapiens, GI301129207, Length=205, Percent_Identity=41.9512195121951, Blast_Score=174, Evalue=5e-44,
Organism=Homo sapiens, GI57863312, Length=205, Percent_Identity=41.9512195121951, Blast_Score=174, Evalue=6e-44,
Organism=Homo sapiens, GI18699734, Length=217, Percent_Identity=39.1705069124424, Blast_Score=173, Evalue=9e-44,
Organism=Homo sapiens, GI13899253, Length=216, Percent_Identity=36.5740740740741, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI209863022, Length=152, Percent_Identity=33.5526315789474, Blast_Score=100, Evalue=9e-22,
Organism=Escherichia coli, GI87082034, Length=212, Percent_Identity=51.8867924528302, Blast_Score=221, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17539894, Length=211, Percent_Identity=40.2843601895735, Blast_Score=168, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17539892, Length=211, Percent_Identity=40.2843601895735, Blast_Score=168, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71981181, Length=220, Percent_Identity=34.5454545454545, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6324339, Length=194, Percent_Identity=35.5670103092784, Blast_Score=110, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320223, Length=216, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324200, Length=201, Percent_Identity=26.3681592039801, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24649624, Length=216, Percent_Identity=38.4259259259259, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI221458995, Length=216, Percent_Identity=37.962962962963, Blast_Score=164, Evalue=4e-41,
Organism=Drosophila melanogaster, GI45550449, Length=209, Percent_Identity=40.6698564593301, Blast_Score=164, Evalue=5e-41,
Organism=Drosophila melanogaster, GI28573516, Length=209, Percent_Identity=40.6698564593301, Blast_Score=164, Evalue=5e-41,
Organism=Drosophila melanogaster, GI28573514, Length=209, Percent_Identity=40.6698564593301, Blast_Score=164, Evalue=5e-41,
Organism=Drosophila melanogaster, GI28573512, Length=209, Percent_Identity=40.6698564593301, Blast_Score=164, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URK_OCEIH (Q8EPT5)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692924.1
- ProteinModelPortal:   Q8EPT5
- GeneID:   1018486
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2003
- NMPDR:   fig|221109.1.peg.2002
- HOGENOM:   HBG527126
- OMA:   NQFVEPT
- ProtClustDB:   PRK05480
- BioCyc:   OIHE221109:OB2003-MONOMER
- BRENDA:   2.7.1.48
- GO:   GO:0005737
- HAMAP:   MF_00551
- InterPro:   IPR006083
- InterPro:   IPR000764
- PANTHER:   PTHR10285:SF6
- PRINTS:   PR00988
- TIGRFAMs:   TIGR00235

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.48

Molecular weight: Translated: 24261; Mature: 24130

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQKPVVIGVAGGSGSGKTSVTRSICQRFTETSILVIEQDYYYKDQSHLPFEERLNTNY
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCEECCCCCCCHHHHCCCCC
DHPLAFDNDLLIEHLQQLMHNEPIEKPVYDYKIHTRSKDVIHVEPKEVIIVEGILILEDP
CCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEECCCEEEEEEEEEEECCC
RLVDLMDIKVYVDTDADLRIIRRLMRDIKERGRTLDSVIDQYIQNVRPSHLQFIEPTKRY
CEEEEEEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHEEECCCHHH
ADIIIPEGGQNHVAIDIMASKIEKILSRGL
EEEEECCCCCCCEEEHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKQKPVVIGVAGGSGSGKTSVTRSICQRFTETSILVIEQDYYYKDQSHLPFEERLNTNY
CCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCEECCCCCCCHHHHCCCCC
DHPLAFDNDLLIEHLQQLMHNEPIEKPVYDYKIHTRSKDVIHVEPKEVIIVEGILILEDP
CCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEECCCEEEEEEEEEEECCC
RLVDLMDIKVYVDTDADLRIIRRLMRDIKERGRTLDSVIDQYIQNVRPSHLQFIEPTKRY
CEEEEEEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHEEECCCHHH
ADIIIPEGGQNHVAIDIMASKIEKILSRGL
EEEEECCCCCCCEEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376