Click here to switch to the map view.

The map label for this gene is yqeV [H]

Identifier: 23099419

GI number: 23099419

Start: 1990955

End: 1992307

Strand: Reverse

Name: yqeV [H]

Synonym: OB1964

Alternate gene names: 23099419

Gene position: 1992307-1990955 (Counterclockwise)

Preceding gene: 23099420

Following gene: 23099418

Centisome position: 54.88

GC content: 35.7

Gene sequence:

>1353_bases
ATGACAACAGTGGCTTTTCACACGCTAGGATGTAAAGTAAATCATTATGAAACAGAAGGAATCTGGAGAATGTTTAAAGA
AGAAGGATATGAGAGAGTAGACTTTGATCATAATTCGGATGTTTATGTGATTAATACTTGTACGGTTACTAATTCTGGTG
ATAAAAAAAGCAGGCAAGTCATCCGTAGAGCGATTCGTAAAAATCCAGATGCAGTTGTCTGTGTAACAGGTTGCTATGCT
CAAACGTCGCCTGGTGAGATTATGGAGATTCCTGGTGTAGATATAGTAGTAGGCACACAAGATCGTAAAAATATCTTCTC
CTATATTGAAGAACATCAGAAAACCAAAGAACCAGTAAATGGAGTATCAAACATAATGAAAAATCGTGTGTTTGAAGAAA
TGGACGTCCCAGTATTCACAGACCGTACACGTGCATCATTGAAAATACAAGAAGGTTGTAACAACTTCTGTACATTTTGT
ATTATCCCATGGTCTAGAGGATTATTGCGATCTAGGGATCCAAAGAATGTGATAGAGCAGGCTACTAAATTAGTAAAAGC
AGGATATAAAGAGCTCGTTCTGACTGGGATTCATACAGCTGGGTATGGAGAAGATATGAAAGACTATAATTTTGCTATGT
TACTAAGAGAGCTAGAAGAAGTAGAAGGATTAGAGCGAATTCGAATTAGTTCTATTGAAGCGAGTCAAATTACGGATGAA
GTAATTGATGTAATAGATCAAAGCAATAAAATTGTGCGACATCTGCATGTACCGCTTCAATCAGGATCTGATAGTGTTCT
AGCTCGTATGCGCAGAAAATATTCTACAAGCTTTTATAAGGAGAAGGTAAATAAACTTCAAAAAGCATTACCTGGACTAG
CAATTACTTCCGATGTTATCGTTGGATTTCCAGGCGAAACAGAGGAAGAGTTTCAACAAACGTATTCTTTTATCAAAGAA
ATAGGCTATGCAGAGTTACATGTATTTCCATTCTCGAGAAGAACAGGAACACCAGCTGCTCGTATGGAAAATCAAGTGGA
AGATCCAATAAAAGAAAAACGAGTTCATGATTTAATTGCACTCTCCGATCAACTTGCTAAAGAATATGCTTCAAGATATG
AAAATGAAGTATTAGAGGTAATTCCAGAAGAACAAGTAGATGAGAATCAATCCAATACATTAGTTGGTTATACTGATAAT
TATATGAAAGTACAATTTGAAGGTACACCAGACTTAATAGGAAAGATTGTTAAAGTCAAAGTAACTCAATCAGGATATCC
TATTAATCAAGGTGTTTTTGTTCGTGTAATGGAACATTCAACTCACAGTAAAGCAAAAGTTTATGAAGCTTAA

Upstream 100 bases:

>100_bases
TACCCATTCGCCTTGGAAAACGAATTTTACGCACAGAAACAGCCGCTTTATATGCTCTATCGAGTATTTCCTATCAATTA
GAAGAATTGAGGTGTTTAAC

Downstream 100 bases:

>100_bases
CAACACAGAAAGGAAGAGATTTAATGGATTTAGCTAAATATATTGATCATACTCAATTAAAACCAGATACTACAAAACAA
AGTATTGTAAAAATTGTGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MTTVAFHTLGCKVNHYETEGIWRMFKEEGYERVDFDHNSDVYVINTCTVTNSGDKKSRQVIRRAIRKNPDAVVCVTGCYA
QTSPGEIMEIPGVDIVVGTQDRKNIFSYIEEHQKTKEPVNGVSNIMKNRVFEEMDVPVFTDRTRASLKIQEGCNNFCTFC
IIPWSRGLLRSRDPKNVIEQATKLVKAGYKELVLTGIHTAGYGEDMKDYNFAMLLRELEEVEGLERIRISSIEASQITDE
VIDVIDQSNKIVRHLHVPLQSGSDSVLARMRRKYSTSFYKEKVNKLQKALPGLAITSDVIVGFPGETEEEFQQTYSFIKE
IGYAELHVFPFSRRTGTPAARMENQVEDPIKEKRVHDLIALSDQLAKEYASRYENEVLEVIPEEQVDENQSNTLVGYTDN
YMKVQFEGTPDLIGKIVKVKVTQSGYPINQGVFVRVMEHSTHSKAKVYEA

Sequences:

>Translated_450_residues
MTTVAFHTLGCKVNHYETEGIWRMFKEEGYERVDFDHNSDVYVINTCTVTNSGDKKSRQVIRRAIRKNPDAVVCVTGCYA
QTSPGEIMEIPGVDIVVGTQDRKNIFSYIEEHQKTKEPVNGVSNIMKNRVFEEMDVPVFTDRTRASLKIQEGCNNFCTFC
IIPWSRGLLRSRDPKNVIEQATKLVKAGYKELVLTGIHTAGYGEDMKDYNFAMLLRELEEVEGLERIRISSIEASQITDE
VIDVIDQSNKIVRHLHVPLQSGSDSVLARMRRKYSTSFYKEKVNKLQKALPGLAITSDVIVGFPGETEEEFQQTYSFIKE
IGYAELHVFPFSRRTGTPAARMENQVEDPIKEKRVHDLIALSDQLAKEYASRYENEVLEVIPEEQVDENQSNTLVGYTDN
YMKVQFEGTPDLIGKIVKVKVTQSGYPINQGVFVRVMEHSTHSKAKVYEA
>Mature_449_residues
TTVAFHTLGCKVNHYETEGIWRMFKEEGYERVDFDHNSDVYVINTCTVTNSGDKKSRQVIRRAIRKNPDAVVCVTGCYAQ
TSPGEIMEIPGVDIVVGTQDRKNIFSYIEEHQKTKEPVNGVSNIMKNRVFEEMDVPVFTDRTRASLKIQEGCNNFCTFCI
IPWSRGLLRSRDPKNVIEQATKLVKAGYKELVLTGIHTAGYGEDMKDYNFAMLLRELEEVEGLERIRISSIEASQITDEV
IDVIDQSNKIVRHLHVPLQSGSDSVLARMRRKYSTSFYKEKVNKLQKALPGLAITSDVIVGFPGETEEEFQQTYSFIKEI
GYAELHVFPFSRRTGTPAARMENQVEDPIKEKRVHDLIALSDQLAKEYASRYENEVLEVIPEEQVDENQSNTLVGYTDNY
MKVQFEGTPDLIGKIVKVKVTQSGYPINQGVFVRVMEHSTHSKAKVYEA

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI28872782, Length=441, Percent_Identity=27.891156462585, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI28872784, Length=441, Percent_Identity=27.891156462585, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI93277076, Length=460, Percent_Identity=30, Blast_Score=171, Evalue=2e-42,
Organism=Escherichia coli, GI1786882, Length=428, Percent_Identity=33.1775700934579, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1787057, Length=398, Percent_Identity=30.6532663316583, Blast_Score=166, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17553146, Length=388, Percent_Identity=27.5773195876289, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI71996771, Length=356, Percent_Identity=28.3707865168539, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21356207, Length=407, Percent_Identity=28.5012285012285, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI19922432, Length=430, Percent_Identity=28.6046511627907, Blast_Score=161, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 51236; Mature: 51105

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVAFHTLGCKVNHYETEGIWRMFKEEGYERVDFDHNSDVYVINTCTVTNSGDKKSRQV
CCEEEEEEECCEEEEECHHHHHHHHHHCCCCEECCCCCCCEEEEEEEEECCCCCHHHHHH
IRRAIRKNPDAVVCVTGCYAQTSPGEIMEIPGVDIVVGTQDRKNIFSYIEEHQKTKEPVN
HHHHHHCCCCEEEEEEECCCCCCCCCEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
GVSNIMKNRVFEEMDVPVFTDRTRASLKIQEGCNNFCTFCIIPWSRGLLRSRDPKNVIEQ
HHHHHHHHHHHHHCCCCEEECCCCCEEEHHHCCCCEEEEEEEECCCCHHCCCCHHHHHHH
ATKLVKAGYKELVLTGIHTAGYGEDMKDYNFAMLLRELEEVEGLERIRISSIEASQITDE
HHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHH
VIDVIDQSNKIVRHLHVPLQSGSDSVLARMRRKYSTSFYKEKVNKLQKALPGLAITSDVI
HHHHHHCCCCEEHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEE
VGFPGETEEEFQQTYSFIKEIGYAELHVFPFSRRTGTPAARMENQVEDPIKEKRVHDLIA
EECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHCHHHHHHHHHHHH
LSDQLAKEYASRYENEVLEVIPEEQVDENQSNTLVGYTDNYMKVQFEGTPDLIGKIVKVK
HHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEEECCEEEEEECCCHHHHCCEEEEE
VTQSGYPINQGVFVRVMEHSTHSKAKVYEA
EECCCCCCCCCCEEEEEECCCCCCCEECCC
>Mature Secondary Structure 
TTVAFHTLGCKVNHYETEGIWRMFKEEGYERVDFDHNSDVYVINTCTVTNSGDKKSRQV
CEEEEEEECCEEEEECHHHHHHHHHHCCCCEECCCCCCCEEEEEEEEECCCCCHHHHHH
IRRAIRKNPDAVVCVTGCYAQTSPGEIMEIPGVDIVVGTQDRKNIFSYIEEHQKTKEPVN
HHHHHHCCCCEEEEEEECCCCCCCCCEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
GVSNIMKNRVFEEMDVPVFTDRTRASLKIQEGCNNFCTFCIIPWSRGLLRSRDPKNVIEQ
HHHHHHHHHHHHHCCCCEEECCCCCEEEHHHCCCCEEEEEEEECCCCHHCCCCHHHHHHH
ATKLVKAGYKELVLTGIHTAGYGEDMKDYNFAMLLRELEEVEGLERIRISSIEASQITDE
HHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHH
VIDVIDQSNKIVRHLHVPLQSGSDSVLARMRRKYSTSFYKEKVNKLQKALPGLAITSDVI
HHHHHHCCCCEEHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEE
VGFPGETEEEFQQTYSFIKEIGYAELHVFPFSRRTGTPAARMENQVEDPIKEKRVHDLIA
EECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHCHHHHHHHHHHHH
LSDQLAKEYASRYENEVLEVIPEEQVDENQSNTLVGYTDNYMKVQFEGTPDLIGKIVKVK
HHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEEECCEEEEEECCCHHHHCCEEEEE
VTQSGYPINQGVFVRVMEHSTHSKAKVYEA
EECCCCCCCCCCEEEEEECCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9023197; 9384377 [H]