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The map label for this gene is dra

Identifier: 23099418

GI number: 23099418

Start: 1990266

End: 1990931

Strand: Reverse

Name: dra

Synonym: OB1963

Alternate gene names: 23099418

Gene position: 1990931-1990266 (Counterclockwise)

Preceding gene: 23099419

Following gene: 23099417

Centisome position: 54.84

GC content: 36.64

Gene sequence:

>666_bases
ATGGATTTAGCTAAATATATTGATCATACTCAATTAAAACCAGATACTACAAAACAAAGTATTGTAAAAATTGTGGAAGA
GGCAAAACAACATGAATTTGCTTCAGTATGTGTTAATCCACACTGGGTTTCTTACTGTTATAATGAATTAAAAGATACAC
CAGTTAAAGTTTGTACAGTAATTGGATTCCCATTAGGAGCCACTTCTACTGAAACGAAAATTTTTGAAACCAATCAGGCT
ATTGCTGATGGTGCTACAGAAGTAGACATGGTAATTAATGTCGGTGAATTAAAATCGAATAATGATGCTTTTGTTGAAAA
AGACATCCGTGCTGTTGTTGAAGCAGCAAAAGGTAAAGCTTTAACAAAAGTGATAATTGAAACAAGTCTTTTAACAGAAG
ATGAAAAAGTACGTGCTTGTAAATTAGCAAAAAATGCAGAGGCTGACTATGTAAAAACTTCTACTGGGTTCTCTGGTGGC
GGCGCAACTGTTGAGGATATTCGCTTAATGCGAGAGACAGTAGGACCTGAAATGGGAGTGAAAGCATCTGGTGGTGTTCG
TGATTTAGAGCAAACAGAAGCAATGATTGAAGCTGGAGCAACTAGAATTGGAGCTAGTTCTGGGGTAGCGATTGTCTCAG
GAGAACAAGGTACATCAGATTACTAA

Upstream 100 bases:

>100_bases
ATCCTATTAATCAAGGTGTTTTTGTTCGTGTAATGGAACATTCAACTCACAGTAAAGCAAAAGTTTATGAAGCTTAACAA
CACAGAAAGGAAGAGATTTA

Downstream 100 bases:

>100_bases
ATTTCAAATTCATCTTTGTTCCCTATTTTTATTATTAGATACAAATAACCGTTGACCTATAAGATTGTTTATATTATACT
TTATAAAGGCATGAGAATAG

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase 1; DERA 1; Deoxyriboaldolase 1

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MDLAKYIDHTQLKPDTTKQSIVKIVEEAKQHEFASVCVNPHWVSYCYNELKDTPVKVCTVIGFPLGATSTETKIFETNQA
IADGATEVDMVINVGELKSNNDAFVEKDIRAVVEAAKGKALTKVIIETSLLTEDEKVRACKLAKNAEADYVKTSTGFSGG
GATVEDIRLMRETVGPEMGVKASGGVRDLEQTEAMIEAGATRIGASSGVAIVSGEQGTSDY

Sequences:

>Translated_221_residues
MDLAKYIDHTQLKPDTTKQSIVKIVEEAKQHEFASVCVNPHWVSYCYNELKDTPVKVCTVIGFPLGATSTETKIFETNQA
IADGATEVDMVINVGELKSNNDAFVEKDIRAVVEAAKGKALTKVIIETSLLTEDEKVRACKLAKNAEADYVKTSTGFSGG
GATVEDIRLMRETVGPEMGVKASGGVRDLEQTEAMIEAGATRIGASSGVAIVSGEQGTSDY
>Mature_221_residues
MDLAKYIDHTQLKPDTTKQSIVKIVEEAKQHEFASVCVNPHWVSYCYNELKDTPVKVCTVIGFPLGATSTETKIFETNQA
IADGATEVDMVINVGELKSNNDAFVEKDIRAVVEAAKGKALTKVIIETSLLTEDEKVRACKLAKNAEADYVKTSTGFSGG
GATVEDIRLMRETVGPEMGVKASGGVRDLEQTEAMIEAGATRIGASSGVAIVSGEQGTSDY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=219, Percent_Identity=30.1369863013699, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1790841, Length=214, Percent_Identity=33.1775700934579, Blast_Score=84, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17533015, Length=232, Percent_Identity=26.7241379310345, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC1_OCEIH (Q8EPW8)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692884.1
- ProteinModelPortal:   Q8EPW8
- SMR:   Q8EPW8
- GeneID:   1018440
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1963
- NMPDR:   fig|221109.1.peg.1963
- HOGENOM:   HBG636421
- OMA:   GANTPEV
- BioCyc:   OIHE221109:OB1963-MONOMER
- BRENDA:   4.1.2.4
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 23666; Mature: 23666

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: ACT_SITE 152-152 ACT_SITE 181-181

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLAKYIDHTQLKPDTTKQSIVKIVEEAKQHEFASVCVNPHWVSYCYNELKDTPVKVCTV
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHH
IGFPLGATSTETKIFETNQAIADGATEVDMVINVGELKSNNDAFVEKDIRAVVEAAKGKA
HCCCCCCCCCCCEEEECCHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCHH
LTKVIIETSLLTEDEKVRACKLAKNAEADYVKTSTGFSGGGATVEDIRLMRETVGPEMGV
HHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCCC
KASGGVRDLEQTEAMIEAGATRIGASSGVAIVSGEQGTSDY
CCCCCCHHHHHHHHHHHHCCHHCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MDLAKYIDHTQLKPDTTKQSIVKIVEEAKQHEFASVCVNPHWVSYCYNELKDTPVKVCTV
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHH
IGFPLGATSTETKIFETNQAIADGATEVDMVINVGELKSNNDAFVEKDIRAVVEAAKGKA
HCCCCCCCCCCCEEEECCHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCHH
LTKVIIETSLLTEDEKVRACKLAKNAEADYVKTSTGFSGGGATVEDIRLMRETVGPEMGV
HHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCCC
KASGGVRDLEQTEAMIEAGATRIGASSGVAIVSGEQGTSDY
CCCCCCHHHHHHHHHHHHCCHHCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376