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The map label for this gene is glyQ

Identifier: 23099404

GI number: 23099404

Start: 1976924

End: 1977805

Strand: Reverse

Name: glyQ

Synonym: OB1949

Alternate gene names: 23099404

Gene position: 1977805-1976924 (Counterclockwise)

Preceding gene: 23099405

Following gene: 23099403

Centisome position: 54.48

GC content: 36.39

Gene sequence:

>882_bases
ATGAATATACAAGAAATGATTTTAACACTACAAAATCATTGGTCAGAACATAATTGTATACTTATGCAAGCCTATGATAC
AGAAAAAGGTGCAGGTACGATGTCTCCAATGACACTATTAAGAAGTTTAGGTCCAGAGCCTTGGAATGTAGCTTATGTGG
AACCATCTAGACGTCCTGATGATGGTAGATATGGGGAGAATCCGAACCGGCTATATCAACATCATCAATTCCAAGTAATT
ATGAAGCCATCACCAGATAACATTCAAGAACTATATTTAGAGTCATTAAAAAAACTAGGGATTAACCCGTTGGAACATGA
TATTCGTTTTGTGGAAGACAACTGGGAGAATCCAACTTTAGGTGCAGCGGGATTAGGCTGGGAAGTATGGCTAGATGGCA
TGGAAATCACTCAATTCACCTATTTCCAGCAAATTGGCGGACTCGAAGCAAATCCTGTAACGGTAGAATTAACATATGGA
ATTGAACGTTTAGCTTCGTATATTCAGGATAAAGAAAATGTGTTTGATCTTGAATGGAATAATGGTGTTACCATTCGAGA
TATCTTTTATCAACCTGAATATGAACATTCCACTTATACTTTTAAAGAGTCTAATACAGATATGCTTTTCGACTTGTTCT
CAATGTATGAACAAGAAGCGAAGCAAACGATGGAAAAAGGACTCGTATTTCCTGCATATGATTATGTGCTTAAATGTTCA
CATACATTTAACCTCCTTGATGCAAAAGGAGTAATTTCCGTAACAGAAAGAACGGGTTACATAGCTCGAATTCGTAATTT
AGCGAGAAGTATTTCCAAAATATATGTTTCCGAACGCGAAAAATTAGGTTTTCCAATGCTTCAAGAGAAAGGAGCTAAAT
AA

Upstream 100 bases:

>100_bases
CTATAGTAGACATAGGGACGGTTTTTCTTATAAAAAAAGTGTGGGATAACAGTATTTAACCTTTAGTGATCCTCGCAGTA
AAAAATAAGGAGTTGACAAT

Downstream 100 bases:

>100_bases
AATATGGCACGTGATGTATTAATTGAGATTGGATTAGAAGAGCTACCTGCGCGATTTATTGATGATGCAGAGTTACAATT
ATATACCAAAACAAAGCAGT

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNIQEMILTLQNHWSEHNCILMQAYDTEKGAGTMSPMTLLRSLGPEPWNVAYVEPSRRPDDGRYGENPNRLYQHHQFQVI
MKPSPDNIQELYLESLKKLGINPLEHDIRFVEDNWENPTLGAAGLGWEVWLDGMEITQFTYFQQIGGLEANPVTVELTYG
IERLASYIQDKENVFDLEWNNGVTIRDIFYQPEYEHSTYTFKESNTDMLFDLFSMYEQEAKQTMEKGLVFPAYDYVLKCS
HTFNLLDAKGVISVTERTGYIARIRNLARSISKIYVSEREKLGFPMLQEKGAK

Sequences:

>Translated_293_residues
MNIQEMILTLQNHWSEHNCILMQAYDTEKGAGTMSPMTLLRSLGPEPWNVAYVEPSRRPDDGRYGENPNRLYQHHQFQVI
MKPSPDNIQELYLESLKKLGINPLEHDIRFVEDNWENPTLGAAGLGWEVWLDGMEITQFTYFQQIGGLEANPVTVELTYG
IERLASYIQDKENVFDLEWNNGVTIRDIFYQPEYEHSTYTFKESNTDMLFDLFSMYEQEAKQTMEKGLVFPAYDYVLKCS
HTFNLLDAKGVISVTERTGYIARIRNLARSISKIYVSEREKLGFPMLQEKGAK
>Mature_293_residues
MNIQEMILTLQNHWSEHNCILMQAYDTEKGAGTMSPMTLLRSLGPEPWNVAYVEPSRRPDDGRYGENPNRLYQHHQFQVI
MKPSPDNIQELYLESLKKLGINPLEHDIRFVEDNWENPTLGAAGLGWEVWLDGMEITQFTYFQQIGGLEANPVTVELTYG
IERLASYIQDKENVFDLEWNNGVTIRDIFYQPEYEHSTYTFKESNTDMLFDLFSMYEQEAKQTMEKGLVFPAYDYVLKCS
HTFNLLDAKGVISVTERTGYIARIRNLARSISKIYVSEREKLGFPMLQEKGAK

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=294, Percent_Identity=60.5442176870748, Blast_Score=377, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_OCEIH (Q8EPY1)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692870.1
- ProteinModelPortal:   Q8EPY1
- SMR:   Q8EPY1
- GeneID:   1018426
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1949
- NMPDR:   fig|221109.1.peg.1949
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- ProtClustDB:   PRK09348
- BioCyc:   OIHE221109:OB1949-MONOMER
- BRENDA:   6.1.1.14
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 34021; Mature: 34021

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQEMILTLQNHWSEHNCILMQAYDTEKGAGTMSPMTLLRSLGPEPWNVAYVEPSRRPD
CCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCC
DGRYGENPNRLYQHHQFQVIMKPSPDNIQELYLESLKKLGINPLEHDIRFVEDNWENPTL
CCCCCCCHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHEEEECCCCCCCC
GAAGLGWEVWLDGMEITQFTYFQQIGGLEANPVTVELTYGIERLASYIQDKENVFDLEWN
CCCCCCHHHEECCCHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHCCCCEEEEECC
NGVTIRDIFYQPEYEHSTYTFKESNTDMLFDLFSMYEQEAKQTMEKGLVFPAYDYVLKCS
CCEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEEC
HTFNLLDAKGVISVTERTGYIARIRNLARSISKIYVSEREKLGFPMLQEKGAK
CCEEEECCCCEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
>Mature Secondary Structure
MNIQEMILTLQNHWSEHNCILMQAYDTEKGAGTMSPMTLLRSLGPEPWNVAYVEPSRRPD
CCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCC
DGRYGENPNRLYQHHQFQVIMKPSPDNIQELYLESLKKLGINPLEHDIRFVEDNWENPTL
CCCCCCCHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHEEEECCCCCCCC
GAAGLGWEVWLDGMEITQFTYFQQIGGLEANPVTVELTYGIERLASYIQDKENVFDLEWN
CCCCCCHHHEECCCHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHCCCCEEEEECC
NGVTIRDIFYQPEYEHSTYTFKESNTDMLFDLFSMYEQEAKQTMEKGLVFPAYDYVLKCS
CCEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEEC
HTFNLLDAKGVISVTERTGYIARIRNLARSISKIYVSEREKLGFPMLQEKGAK
CCEEEECCCCEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376