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The map label for this gene is cbaA [H]

Identifier: 23099201

GI number: 23099201

Start: 1784397

End: 1786085

Strand: Direct

Name: cbaA [H]

Synonym: OB1746

Alternate gene names: 23099201

Gene position: 1784397-1786085 (Clockwise)

Preceding gene: 23099200

Following gene: 23099210

Centisome position: 49.15

GC content: 35.52

Gene sequence:

>1689_bases
ATGGCACTTGCTAATTTACAAACATTCGAAGATATTTCAACTGAATCTATCGTGATTACAAAAACAGATTCTAAATTATA
CTTATCATTTATTTATGTAGCAATTATTTCTTTATTCTTAGGTGGACTAATGGGGTTATTGCAAGTATTAGTACGAACAG
GTGAATTTACTCTCCCTTTTGGAATTGGTTATTATCAAATTCTTACGTTCCATGGTGTTGTTCTTGCTTTAGTATTAACT
ACTTTTTTTATTATTGGATTTCAATTTGCTTTAATGGGAAAAACAGTAGGTATTTCTGAAAAACAGCGCAAATTTGCTTG
GTTAGCTTTTTGGGTAATGACTATTGGTACATCAATGACTGCTGTTACAATTCTAATAGGGAAAGCAAATGTGCTCTACA
CCTTTTACGCACCCTTAAAAGCACATCCCCTCTTCTATATTGGATTAGCTCTTGTTGTTGTGGGGACTTGGATTGCAGCA
ATTGTAAATTGGAGACAACTATTTGTTTGGAAAAAGCAAATTCCAAATCAAAAATCCCCTCTCCTTGCTTTTATGGTTAC
CATTAATATGATTATGTGGGTTATTGCTTCACTAGGTGTAGCTGTAGCGGTATTAGTTCAATTTATTCCATGGTCATTAG
GTTTTGCAGAAACAATCAATGTATTGTTAAGTAGAACGTTATTTTGGTACTTTGGCCATCCTTTAGTTTACTTTTGGTTA
TTACCTGCTTACATGGCTTGGTATGCCATTATACCGAAGATAATTGGAGGTAAACTATTTAGTGACTCCTTAGCACGATT
ATCATTTATTTTGTTTTTATTCTTTTCGATTCCAGTTGGTTTTCATCATCAATTAACAGAACCAGGAATAGATCCTACAT
GGAAGTTTATACAAGTTGTATTAACCTTCATGGTTATTATTCCTAGTTTAATGACAGCATTTTCGATGTTCGCTACGTTT
GAAATTACTGGAAGAAAAAAAGGACATAAAGGTTTATTTGGTTGGTTTAAAAACTTACCTTGGCAAGATGTCCGCTTCTT
TGCTCCATTTGTAGGTATGCTTGCATTTATACCAGGTGGTATTGGCGGAATCATTAATGCCTCTCATCAAATGAATACAG
TAGTCCATAACACAATTTGGGTAACAGGACACTTTCATCTAACTGTTGCGACGACTGTTCTCTTAACGTTTTTTGGGATA
GCGTACTGGTTAATTCCTCATTTAACTGGTAGAAAATTAACGAGAAAAATACACCGTTTAGGTATTTATCAAACCGTGGT
TTGGGCAATTGGGATGACGATTATGTCTGGCGCTATGCATATCCAAGGTTTGTTAGGTGGTCCGAGAAGATCTTCCTATT
CAGAATACGGCGGATCCGAGCAAGCTGTGGACTGGGGTGCATATCAGATGGCTCAAGCGGTTGGTGGTACTATTCTCTTT
ATTGGGATCATTTTGATGGTATATATTTTTATTTATCTAGTATTTTTTGCACCAGAAGGAAACGAAGAATTCCCTATTGC
TGAGGAAGAAAATCATGCACCAGCTACTCCCAAATGGATGGAGAATTGGAAATTATGGATTGGTATAACAATAGCATTAA
TTTTATTTGCTTATACCATCCCTGTGGTTGATATTATTCAAAACGCACCACCTGGATCACCACCATTTGATGCTATAATC
GGTAATTAA

Upstream 100 bases:

>100_bases
AAGTTCAAATGAATAATGTTGGAGAATTTACCTTGTTATGTAATGAGTATTGCGGAGTTGGACATCATATGATGTTTACG
ACAGTGGAGGTGTATGAATA

Downstream 100 bases:

>100_bases
TTTGTAGAGAATTAGTTGAATCTAACTAGGAAAAGAAGCCCCTCCTTTTCCTAGTGGTTTTCAAGCCCAGATATTCTAAG
CAGGAATCGCTGTTCAAAAA

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome c ba(3) subunit I; Cytochrome c oxidase polypeptide I; Cytochrome cba3 subunit 1 [H]

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MALANLQTFEDISTESIVITKTDSKLYLSFIYVAIISLFLGGLMGLLQVLVRTGEFTLPFGIGYYQILTFHGVVLALVLT
TFFIIGFQFALMGKTVGISEKQRKFAWLAFWVMTIGTSMTAVTILIGKANVLYTFYAPLKAHPLFYIGLALVVVGTWIAA
IVNWRQLFVWKKQIPNQKSPLLAFMVTINMIMWVIASLGVAVAVLVQFIPWSLGFAETINVLLSRTLFWYFGHPLVYFWL
LPAYMAWYAIIPKIIGGKLFSDSLARLSFILFLFFSIPVGFHHQLTEPGIDPTWKFIQVVLTFMVIIPSLMTAFSMFATF
EITGRKKGHKGLFGWFKNLPWQDVRFFAPFVGMLAFIPGGIGGIINASHQMNTVVHNTIWVTGHFHLTVATTVLLTFFGI
AYWLIPHLTGRKLTRKIHRLGIYQTVVWAIGMTIMSGAMHIQGLLGGPRRSSYSEYGGSEQAVDWGAYQMAQAVGGTILF
IGIILMVYIFIYLVFFAPEGNEEFPIAEEENHAPATPKWMENWKLWIGITIALILFAYTIPVVDIIQNAPPGSPPFDAII
GN

Sequences:

>Translated_562_residues
MALANLQTFEDISTESIVITKTDSKLYLSFIYVAIISLFLGGLMGLLQVLVRTGEFTLPFGIGYYQILTFHGVVLALVLT
TFFIIGFQFALMGKTVGISEKQRKFAWLAFWVMTIGTSMTAVTILIGKANVLYTFYAPLKAHPLFYIGLALVVVGTWIAA
IVNWRQLFVWKKQIPNQKSPLLAFMVTINMIMWVIASLGVAVAVLVQFIPWSLGFAETINVLLSRTLFWYFGHPLVYFWL
LPAYMAWYAIIPKIIGGKLFSDSLARLSFILFLFFSIPVGFHHQLTEPGIDPTWKFIQVVLTFMVIIPSLMTAFSMFATF
EITGRKKGHKGLFGWFKNLPWQDVRFFAPFVGMLAFIPGGIGGIINASHQMNTVVHNTIWVTGHFHLTVATTVLLTFFGI
AYWLIPHLTGRKLTRKIHRLGIYQTVVWAIGMTIMSGAMHIQGLLGGPRRSSYSEYGGSEQAVDWGAYQMAQAVGGTILF
IGIILMVYIFIYLVFFAPEGNEEFPIAEEENHAPATPKWMENWKLWIGITIALILFAYTIPVVDIIQNAPPGSPPFDAII
GN
>Mature_561_residues
ALANLQTFEDISTESIVITKTDSKLYLSFIYVAIISLFLGGLMGLLQVLVRTGEFTLPFGIGYYQILTFHGVVLALVLTT
FFIIGFQFALMGKTVGISEKQRKFAWLAFWVMTIGTSMTAVTILIGKANVLYTFYAPLKAHPLFYIGLALVVVGTWIAAI
VNWRQLFVWKKQIPNQKSPLLAFMVTINMIMWVIASLGVAVAVLVQFIPWSLGFAETINVLLSRTLFWYFGHPLVYFWLL
PAYMAWYAIIPKIIGGKLFSDSLARLSFILFLFFSIPVGFHHQLTEPGIDPTWKFIQVVLTFMVIIPSLMTAFSMFATFE
ITGRKKGHKGLFGWFKNLPWQDVRFFAPFVGMLAFIPGGIGGIINASHQMNTVVHNTIWVTGHFHLTVATTVLLTFFGIA
YWLIPHLTGRKLTRKIHRLGIYQTVVWAIGMTIMSGAMHIQGLLGGPRRSSYSEYGGSEQAVDWGAYQMAQAVGGTILFI
GIILMVYIFIYLVFFAPEGNEEFPIAEEENHAPATPKWMENWKLWIGITIALILFAYTIPVVDIIQNAPPGSPPFDAIIG
N

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. This Ubiquinol Oxidase Shows Proton Pump Activity Across The Membrane In Addition To The Electron T

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6226519, Length=238, Percent_Identity=23.9495798319328, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 63011; Mature: 62880

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALANLQTFEDISTESIVITKTDSKLYLSFIYVAIISLFLGGLMGLLQVLVRTGEFTLPF
CCCCCCCHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
GIGYYQILTFHGVVLALVLTTFFIIGFQFALMGKTVGISEKQRKFAWLAFWVMTIGTSMT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHH
AVTILIGKANVLYTFYAPLKAHPLFYIGLALVVVGTWIAAIVNWRQLFVWKKQIPNQKSP
HHHEEEECCCEEEEEECCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LLAFMVTINMIMWVIASLGVAVAVLVQFIPWSLGFAETINVLLSRTLFWYFGHPLVYFWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LPAYMAWYAIIPKIIGGKLFSDSLARLSFILFLFFSIPVGFHHQLTEPGIDPTWKFIQVV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
LTFMVIIPSLMTAFSMFATFEITGRKKGHKGLFGWFKNLPWQDVRFFAPFVGMLAFIPGG
HHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
IGGIINASHQMNTVVHNTIWVTGHFHLTVATTVLLTFFGIAYWLIPHLTGRKLTRKIHRL
CHHHHCCCHHHHHHHEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GIYQTVVWAIGMTIMSGAMHIQGLLGGPRRSSYSEYGGSEQAVDWGAYQMAQAVGGTILF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHCCHHHH
IGIILMVYIFIYLVFFAPEGNEEFPIAEEENHAPATPKWMENWKLWIGITIALILFAYTI
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHH
PVVDIIQNAPPGSPPFDAIIGN
HHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ALANLQTFEDISTESIVITKTDSKLYLSFIYVAIISLFLGGLMGLLQVLVRTGEFTLPF
CCCCCCHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC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HHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7657607; 10338009; 10775261 [H]