Click here to switch to the map view.

The map label for this gene is recU

Identifier: 23099210

GI number: 23099210

Start: 1792945

End: 1793535

Strand: Direct

Name: recU

Synonym: OB1755

Alternate gene names: 23099210

Gene position: 1792945-1793535 (Clockwise)

Preceding gene: 23099201

Following gene: 23099211

Centisome position: 49.39

GC content: 32.99

Gene sequence:

>591_bases
TTGAATTATCCGAATGGTCAACAGAAGGTGACAACCAACCATGTTGTACAAAAACAGGATAATCGTATGTTTAGCAATAG
AGGAATGTCCTTAGAGGATGACATTAATGCAACAAATGAATTTTATCTGGAAACAAATCAAGCAGTTATACACAAAAAAC
CAACCCCTGTTCAGATTGTTAATGTACATTATCCGAAAAGAAGCGCAGCAGTAATAACAGAAGCTTATTTCAAACAAGCC
TCTACTACTGATTATAACGGCATTTATAAAGGTAAATATATTGACTTCGAGGCAAAGGAAACGAAGAATAAAACATCATT
TCCATTAGCTAATATACATGAACATCAAATCAATCATATGCAAAAGGTTATTGATCAACAGGGTATTTGTTTTATGTTAA
TTCGATTTACAGCTCATGATGAGACATACTTATTGGATGCCAAAGCACTTTTAACATTTTGGAATCTTAAGCAAGATGGA
GGGAAGAAATCGATTCCCTATGATATGATAAGAAACCAGAGTCAGCTTATTCCATTTCATTACCAGAAAAGAGTAGATTA
TTTAGCTGCTGTAGATAAGCTTTATTTTTAA

Upstream 100 bases:

>100_bases
GTAGTTTACTCATCAATTACCACATACTTTCTAAAAGAGTTATGAATTATCTTTTGCTTCTTTTCTAAATATCATGCAAA
AGGAGCGAGGAGGGATTTTA

Downstream 100 bases:

>100_bases
TTACGGAGGTAGAAACTAATGGCAGAGAATAAAGGCCAAAGTAGAACAGCAAGAAGACAACAACAGAAGAAATCAAAGAA
ATCAAGAAAATCGAATAAAC

Product: Holliday junction-specific endonuclease

Products: NA

Alternate protein names: Recombination protein U homolog

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MNYPNGQQKVTTNHVVQKQDNRMFSNRGMSLEDDINATNEFYLETNQAVIHKKPTPVQIVNVHYPKRSAAVITEAYFKQA
STTDYNGIYKGKYIDFEAKETKNKTSFPLANIHEHQINHMQKVIDQQGICFMLIRFTAHDETYLLDAKALLTFWNLKQDG
GKKSIPYDMIRNQSQLIPFHYQKRVDYLAAVDKLYF

Sequences:

>Translated_196_residues
MNYPNGQQKVTTNHVVQKQDNRMFSNRGMSLEDDINATNEFYLETNQAVIHKKPTPVQIVNVHYPKRSAAVITEAYFKQA
STTDYNGIYKGKYIDFEAKETKNKTSFPLANIHEHQINHMQKVIDQQGICFMLIRFTAHDETYLLDAKALLTFWNLKQDG
GKKSIPYDMIRNQSQLIPFHYQKRVDYLAAVDKLYF
>Mature_196_residues
MNYPNGQQKVTTNHVVQKQDNRMFSNRGMSLEDDINATNEFYLETNQAVIHKKPTPVQIVNVHYPKRSAAVITEAYFKQA
STTDYNGIYKGKYIDFEAKETKNKTSFPLANIHEHQINHMQKVIDQQGICFMLIRFTAHDETYLLDAKALLTFWNLKQDG
GKKSIPYDMIRNQSQLIPFHYQKRVDYLAAVDKLYF

Specific function: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair

COG id: COG3331

COG function: function code R; Penicillin-binding protein-related factor A, putative recombinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recU family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RECU_OCEIH (Q8CXF9)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692676.1
- HSSP:   P39792
- ProteinModelPortal:   Q8CXF9
- SMR:   Q8CXF9
- GeneID:   1018249
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1755
- NMPDR:   fig|221109.1.peg.1756
- HOGENOM:   HBG571967
- OMA:   HYPKRSA
- ProtClustDB:   PRK02234
- BioCyc:   OIHE221109:OB1755-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00130
- InterPro:   IPR004612
- InterPro:   IPR011335
- PIRSF:   PIRSF037785
- TIGRFAMs:   TIGR00648

Pfam domain/function: PF03838 RecU; SSF52980 Restrict_endonuc_II-like_core

EC number: NA

Molecular weight: Translated: 22873; Mature: 22873

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYPNGQQKVTTNHVVQKQDNRMFSNRGMSLEDDINATNEFYLETNQAVIHKKPTPVQIV
CCCCCCCCEECHHHHHHHCCCCHHHHCCCCCCCCCCCCCEEEEECCCEEEECCCCCEEEE
NVHYPKRSAAVITEAYFKQASTTDYNGIYKGKYIDFEAKETKNKTSFPLANIHEHQINHM
EEECCCCHHHHHHHHHHHHCCCCCCCCEECCEEEECCCHHCCCCCCCCCCCHHHHHHHHH
QKVIDQQGICFMLIRFTAHDETYLLDAKALLTFWNLKQDGGKKSIPYDMIRNQSQLIPFH
HHHHCCCCCEEEEEEEECCCCEEEEHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCHH
YQKRVDYLAAVDKLYF
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYPNGQQKVTTNHVVQKQDNRMFSNRGMSLEDDINATNEFYLETNQAVIHKKPTPVQIV
CCCCCCCCEECHHHHHHHCCCCHHHHCCCCCCCCCCCCCEEEEECCCEEEECCCCCEEEE
NVHYPKRSAAVITEAYFKQASTTDYNGIYKGKYIDFEAKETKNKTSFPLANIHEHQINHM
EEECCCCHHHHHHHHHHHHCCCCCCCCEECCEEEECCCHHCCCCCCCCCCCHHHHHHHHH
QKVIDQQGICFMLIRFTAHDETYLLDAKALLTFWNLKQDGGKKSIPYDMIRNQSQLIPFH
HHHHCCCCCEEEEEEEECCCCEEEEHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCHH
YQKRVDYLAAVDKLYF
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376