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The map label for this gene is ydfG [C]

Identifier: 23099177

GI number: 23099177

Start: 1768146

End: 1769018

Strand: Reverse

Name: ydfG [C]

Synonym: OB1722

Alternate gene names: 23099177

Gene position: 1769018-1768146 (Counterclockwise)

Preceding gene: 23099184

Following gene: 23099172

Centisome position: 48.73

GC content: 35.85

Gene sequence:

>873_bases
ATGCAAAATAAAACGATAATAGTAACCGGCGCAAACACTGGAATGGGATTAGCAACAACGATAGAACTTGCTAAAAAAGG
TATTCATGTAATTATGGCATGTAGAGATACTAAACGCGGTAACGAAGCAAAAGAAAAAGCAATGGAGGAAAGCAACTCAA
CGAATATCTCATTATATCAATGTGATTTAGGTTCTATGGAAAGTATATCTAAATTTGCAGATCAAATAAAAGAAGACTTT
GACAAGATTGATGGTTTAATCAATAATGCGGGTGTTGTTTCACTTAAACATACCAAGACTGAAGATGGATTTGAATCAAT
GACTGGTGTTAATCACCTCGGTCATTTCTTGCTGACTCACCTTCTCTTAGATGTGTTGAAAAAATCGGAACAAGCTCGAA
TTATTAATGTAGCTTCTGGGGCCTATAAAGCTGGAACGTTAGATTATAATGATATGCATTTTAACAATCGTTCATTTAAT
GTAATTAAAGGTTATGGACAGTCTAAATTATGCAATATACTCTTCACACTTGAATTAAATAAACACCTAGAAGGTACCAA
TGTATCAACGTTTGCCCTACATCCTGGAGCGGTATCGACAAGTCTCGGTGTAGACAGACAGACGGGATTTGGTGAAAAAG
TACATCTTCTACTTCGTCCCTTCTTCCTTACATCAGAAGAAGGTGCGGAAACTGCTATATATCTTGCCACAGAACCGAAA
ATTGATCACCTTTCAGGCAGATACTTTTATAAGAAAAAATTACAGCCGACAAAATATAATAAAGTGAATGAAGATGAAGC
TAAAAAATTATGGGACTGGAGCATTAAAGAGCTCGGAATGGAGCATAAAGCTATTGAAGAAGTTGCACCATAA

Upstream 100 bases:

>100_bases
TTATAATTAATAATAACATGGTTCACCAATATTATTTTATCCCTTTTGAAACTTTAATAATACGGGTATAGACTTTTATA
CTAAACAAAAGGAGAATTGC

Downstream 100 bases:

>100_bases
TACAAATAGAGCTATCTCCTATTGTGAGATAGCTCTCTATTTGTATTATTTCATATTTAACGTTCTAGCATTGATCGCTA
CAATAATTGTACTTAGTGAC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MQNKTIIVTGANTGMGLATTIELAKKGIHVIMACRDTKRGNEAKEKAMEESNSTNISLYQCDLGSMESISKFADQIKEDF
DKIDGLINNAGVVSLKHTKTEDGFESMTGVNHLGHFLLTHLLLDVLKKSEQARIINVASGAYKAGTLDYNDMHFNNRSFN
VIKGYGQSKLCNILFTLELNKHLEGTNVSTFALHPGAVSTSLGVDRQTGFGEKVHLLLRPFFLTSEEGAETAIYLATEPK
IDHLSGRYFYKKKLQPTKYNKVNEDEAKKLWDWSIKELGMEHKAIEEVAP

Sequences:

>Translated_290_residues
MQNKTIIVTGANTGMGLATTIELAKKGIHVIMACRDTKRGNEAKEKAMEESNSTNISLYQCDLGSMESISKFADQIKEDF
DKIDGLINNAGVVSLKHTKTEDGFESMTGVNHLGHFLLTHLLLDVLKKSEQARIINVASGAYKAGTLDYNDMHFNNRSFN
VIKGYGQSKLCNILFTLELNKHLEGTNVSTFALHPGAVSTSLGVDRQTGFGEKVHLLLRPFFLTSEEGAETAIYLATEPK
IDHLSGRYFYKKKLQPTKYNKVNEDEAKKLWDWSIKELGMEHKAIEEVAP
>Mature_290_residues
MQNKTIIVTGANTGMGLATTIELAKKGIHVIMACRDTKRGNEAKEKAMEESNSTNISLYQCDLGSMESISKFADQIKEDF
DKIDGLINNAGVVSLKHTKTEDGFESMTGVNHLGHFLLTHLLLDVLKKSEQARIINVASGAYKAGTLDYNDMHFNNRSFN
VIKGYGQSKLCNILFTLELNKHLEGTNVSTFALHPGAVSTSLGVDRQTGFGEKVHLLLRPFFLTSEEGAETAIYLATEPK
IDHLSGRYFYKKKLQPTKYNKVNEDEAKKLWDWSIKELGMEHKAIEEVAP

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI10190746, Length=301, Percent_Identity=41.8604651162791, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI225579078, Length=293, Percent_Identity=41.6382252559727, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI186928839, Length=281, Percent_Identity=39.1459074733096, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI166795268, Length=280, Percent_Identity=38.2142857142857, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI7706523, Length=276, Percent_Identity=34.7826086956522, Blast_Score=169, Evalue=2e-42,
Organism=Homo sapiens, GI19923931, Length=244, Percent_Identity=40.9836065573771, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI146231950, Length=285, Percent_Identity=34.7368421052632, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI193804850, Length=286, Percent_Identity=35.6643356643357, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI13375997, Length=201, Percent_Identity=30.8457711442786, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI72534732, Length=153, Percent_Identity=33.9869281045752, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1787820, Length=241, Percent_Identity=25.3112033195021, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17558006, Length=283, Percent_Identity=36.3957597173145, Blast_Score=160, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17532805, Length=258, Percent_Identity=33.7209302325581, Blast_Score=144, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI193207620, Length=291, Percent_Identity=30.9278350515464, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17532791, Length=260, Percent_Identity=31.5384615384615, Blast_Score=134, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71992402, Length=257, Percent_Identity=29.1828793774319, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17505416, Length=294, Percent_Identity=30.2721088435374, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI72001364, Length=304, Percent_Identity=31.9078947368421, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17535059, Length=258, Percent_Identity=28.6821705426357, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI32565532, Length=207, Percent_Identity=32.8502415458937, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI115533174, Length=182, Percent_Identity=29.6703296703297, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115533172, Length=182, Percent_Identity=29.6703296703297, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6324820, Length=318, Percent_Identity=26.4150943396226, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=224, Percent_Identity=26.3392857142857, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24586328, Length=280, Percent_Identity=44.2857142857143, Blast_Score=205, Evalue=3e-53,
Organism=Drosophila melanogaster, GI19921754, Length=297, Percent_Identity=43.7710437710438, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI22024069, Length=284, Percent_Identity=43.3098591549296, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI45553409, Length=279, Percent_Identity=39.0681003584229, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24647948, Length=279, Percent_Identity=39.0681003584229, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI28573296, Length=284, Percent_Identity=42.2535211267606, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24647946, Length=279, Percent_Identity=39.0681003584229, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI161076371, Length=275, Percent_Identity=40.7272727272727, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI45554248, Length=275, Percent_Identity=40.3636363636364, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24640117, Length=275, Percent_Identity=40.3636363636364, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI20129347, Length=256, Percent_Identity=33.984375, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24647931, Length=309, Percent_Identity=32.0388349514563, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24656154, Length=288, Percent_Identity=32.9861111111111, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI19922628, Length=288, Percent_Identity=32.9861111111111, Blast_Score=122, Evalue=2e-28,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32273; Mature: 32273

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNKTIIVTGANTGMGLATTIELAKKGIHVIMACRDTKRGNEAKEKAMEESNSTNISLYQ
CCCCEEEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEE
CDLGSMESISKFADQIKEDFDKIDGLINNAGVVSLKHTKTEDGFESMTGVNHLGHFLLTH
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHH
LLLDVLKKSEQARIINVASGAYKAGTLDYNDMHFNNRSFNVIKGYGQSKLCNILFTLELN
HHHHHHHCCCCCEEEEECCCCEECCCCCCCCEECCCCCEEEEECCCCCCEEEEEEEEEEC
KHLEGTNVSTFALHPGAVSTSLGVDRQTGFGEKVHLLLRPFFLTSEEGAETAIYLATEPK
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHEEEEEHHHEEECCCCCCEEEEEEECCC
IDHLSGRYFYKKKLQPTKYNKVNEDEAKKLWDWSIKELGMEHKAIEEVAP
CCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MQNKTIIVTGANTGMGLATTIELAKKGIHVIMACRDTKRGNEAKEKAMEESNSTNISLYQ
CCCCEEEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEE
CDLGSMESISKFADQIKEDFDKIDGLINNAGVVSLKHTKTEDGFESMTGVNHLGHFLLTH
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHH
LLLDVLKKSEQARIINVASGAYKAGTLDYNDMHFNNRSFNVIKGYGQSKLCNILFTLELN
HHHHHHHCCCCCEEEEECCCCEECCCCCCCCEECCCCCEEEEECCCCCCEEEEEEEEEEC
KHLEGTNVSTFALHPGAVSTSLGVDRQTGFGEKVHLLLRPFFLTSEEGAETAIYLATEPK
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHEEEEEHHHEEECCCCCCEEEEEEECCC
IDHLSGRYFYKKKLQPTKYNKVNEDEAKKLWDWSIKELGMEHKAIEEVAP
CCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]