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The map label for this gene is bioY [H]

Identifier: 23099172

GI number: 23099172

Start: 1763606

End: 1764175

Strand: Reverse

Name: bioY [H]

Synonym: OB1717

Alternate gene names: 23099172

Gene position: 1764175-1763606 (Counterclockwise)

Preceding gene: 23099177

Following gene: 23099171

Centisome position: 48.59

GC content: 42.46

Gene sequence:

>570_bases
TTGAATCGACAAAGTAATAAATTGAGAATTATGCTTAAAATCTCTATATTTGCCGCAATAACTGCAATACTTGCACAGGT
GGAAATTCCCCTTCCGCTTATTCCAATCAGTGGCCAAACACTGGCAGTAGGGATTGCAGCAACTATTCTTGGAAGCCGTC
AGGGTTCATTGGCAATGGTGCTCTATATGGCGATTGGAATGGTCGGCCTTCCTGTATTCGCTGGATTCAGCGGGGGATCA
CAGGTGCTTGTAGGCCCTTCAGGTGGGTATATTTTTGGGTTTATAGCCGCAGCATACGTTACTGGTCTCATTTTGGAAAA
AACAAGGTTTACAATCCCCATGGCTGTCATCGCAAATATTATGGGAATGTTTGTAACACTAGTTTTTGGTACTATTCAAT
TGAAACTTGTATTGGATCTTGAATGGACTGCTTCCTTGGCTGCCGGAGTATACCCGTTTCTTGCTGTAGGATTCATTAAG
GCATTTCTAGCCAGTTGGATTGGCATTGTTGTCAGAAGACGCCTTATACAAGCAAAACTGCTTGGAGATATGCCAAAAGA
AATTGCATAA

Upstream 100 bases:

>100_bases
TAGAACATTATAATTGAAATTGTAAACTATATAATTGTAATGGTTGACAATTACTCGCTCTACGATTAGAATAATTTTTA
ATCGAAGGGGGACGTTTACA

Downstream 100 bases:

>100_bases
GTTATGACACTAATTGAATAAAATAGATTCAATTAGTGTCACTTTGACCGATAATTTAGACTTATTAAAGCGTTAATTGC
ATAATCCTGTTATAAAACTC

Product: biotin synthase

Products: biotin

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MNRQSNKLRIMLKISIFAAITAILAQVEIPLPLIPISGQTLAVGIAATILGSRQGSLAMVLYMAIGMVGLPVFAGFSGGS
QVLVGPSGGYIFGFIAAAYVTGLILEKTRFTIPMAVIANIMGMFVTLVFGTIQLKLVLDLEWTASLAAGVYPFLAVGFIK
AFLASWIGIVVRRRLIQAKLLGDMPKEIA

Sequences:

>Translated_189_residues
MNRQSNKLRIMLKISIFAAITAILAQVEIPLPLIPISGQTLAVGIAATILGSRQGSLAMVLYMAIGMVGLPVFAGFSGGS
QVLVGPSGGYIFGFIAAAYVTGLILEKTRFTIPMAVIANIMGMFVTLVFGTIQLKLVLDLEWTASLAAGVYPFLAVGFIK
AFLASWIGIVVRRRLIQAKLLGDMPKEIA
>Mature_189_residues
MNRQSNKLRIMLKISIFAAITAILAQVEIPLPLIPISGQTLAVGIAATILGSRQGSLAMVLYMAIGMVGLPVFAGFSGGS
QVLVGPSGGYIFGFIAAAYVTGLILEKTRFTIPMAVIANIMGMFVTLVFGTIQLKLVLDLEWTASLAAGVYPFLAVGFIK
AFLASWIGIVVRRRLIQAKLLGDMPKEIA

Specific function: Probable biotin transporter [H]

COG id: COG1268

COG function: function code R; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BioY family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003784 [H]

Pfam domain/function: PF02632 BioY [H]

EC number: 2.8.1.6

Molecular weight: Translated: 20058; Mature: 20058

Theoretical pI: Translated: 10.81; Mature: 10.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRQSNKLRIMLKISIFAAITAILAQVEIPLPLIPISGQTLAVGIAATILGSRQGSLAMV
CCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCHHHHH
LYMAIGMVGLPVFAGFSGGSQVLVGPSGGYIFGFIAAAYVTGLILEKTRFTIPMAVIANI
HHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGMFVTLVFGTIQLKLVLDLEWTASLAAGVYPFLAVGFIKAFLASWIGIVVRRRLIQAKL
HHHHHHHHHHHHEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGDMPKEIA
HCCCCHHCC
>Mature Secondary Structure
MNRQSNKLRIMLKISIFAAITAILAQVEIPLPLIPISGQTLAVGIAATILGSRQGSLAMV
CCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCHHHHH
LYMAIGMVGLPVFAGFSGGSQVLVGPSGGYIFGFIAAAYVTGLILEKTRFTIPMAVIANI
HHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGMFVTLVFGTIQLKLVLDLEWTASLAAGVYPFLAVGFIKAFLASWIGIVVRRRLIQAKL
HHHHHHHHHHHHEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGDMPKEIA
HCCCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dethiobiotin; sulfur

Specific reaction: dethiobiotin + sulfur = biotin

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2110099; 2507401 [H]