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The map label for this gene is polC

Identifier: 23099048

GI number: 23099048

Start: 1629315

End: 1633601

Strand: Direct

Name: polC

Synonym: OB1593

Alternate gene names: 23099048

Gene position: 1629315-1633601 (Clockwise)

Preceding gene: 23099047

Following gene: 23099049

Centisome position: 44.88

GC content: 36.97

Gene sequence:

>4287_bases
GTGGACATTTCAAAGAAGGAAAAGCTGAAATTATTACTCGAGCAAATTCGAATGCCAGACAATGAAATAGAAGCACATTT
TTCTAATTCATATTTAGACAAAGTAGAAGTACATAAAGCAGATAAGAAATGGCATTTTTATATAAATATAGATCATGTAC
TTCCTTTCCAAACCTATCAATTATTTCATCATTCACTTAAAGAATCCTTTGCATCCATAGCAGAGGTAAGTTTAACGTTG
TCTGCTGAAAATAGACATTGTCCTGAAGGAGATATACAAATATATTGGAAGCATTTTATTGCACAAACTTCTTTGTCTCC
TGCTTATCGTGATCTAGTATTAGATCAAGCGCCTGAAGTATCCAATAATAAGATTATGTTAACTGCTAGAAATGAAGCAG
AAGCATCAGCACTAAAGAAAAGGCTTGAAGCTAAATTTCATGACTTCTGTTTATCAATTGGAAGTTTGCCATACACGCTT
GAAGTTGAAGTGAAAACTAACACAGAAGCTATGCAAGAATTTAGAGATAAAAAAGCATTGGAAGACCAGCAGTTAGTTAT
GAAAACTGTACAAGAAAAAGAAAAGAGAGATAAGGATAAGTCTGTTCCAGATCAACAACCGTTAGCAATTGGTTATAAGA
TTCAAGATGAACCAATAACCATGGATCAAATCATAGATGAAGAGCGACGCATAACGGTACAGGGATATGTATTTGATGCA
GAAGTGCGAGAATTGCGCTCTGGAAGAAGCCTTTTAATAATTAAAGCAACGGATTATACAGATTCCATACAAATAAAAAT
GTTCTCCAAAGGTGATGAAGATGCAGCTAAATTTGCATCTGTAAAAAAAGGTATGTGGGTAAAAGCAAGGGGAAGTATTC
AAACCGACATGTATACGAATGAACTAGCTATGATGGCAAAAGATATTCATGAAATTCACGTATCACAACGAATGGACGAT
GCTTCGGAAGATAAAAAGCGAGTTGAACTTCACACACATACGACGATGAGTCAAATGGATGCAGTAGTTTCTCCAGAGGC
TTTAGTGGAGCAGGCTGCGAAATGGGGACATAAAGCTATTGCTATAACTGACCATGCCGGTGTACAAGGGTTTCCTGATG
CACATAACGCAGGTAAGAAACATGGTGTCAAAGTACTTTATGGTGTAGAAGCAAACTTAGTCGATGACGGTGTACCTATT
GCTTATAATGAAGCCGATCGAAACTTATATGAAGATACTTTTGTTGTATTTGACGTAGAGACAACGGGACTTTCTGCCGT
ATATGATACCATTATTGAATTGGCAGCAGTAAAAATTAAAGGCGGAGAAATTGTTGATCGATTTGAGTCATTTGCTAATC
CGCATCATGCATTGTCTCAGACAACTATCGATTTAACTGGTATTACTGATGACATGGTAAACGATGCTCCAGAAGTGGCG
GATGTACTTAAGGATTTCCACACATGGATGGGTAACGATATATTAGTAGCGCATAATGCTAGTTTTGATATGGGATTTCT
AAATCAAGGATTCCAAAGAATTGATTATGAAAAAGCTTCTAACCCGGTCGTTGATACATTAGAATTAGCACGATTTTTAT
TACCTGAACTACGAAATCACCGCTTAAATACACTTTGTAAGCATCTAGACATCGAATTAACACAGCACCACCGTGCCATT
TATGATGCTGAAGCCACTGGATATCTCCTTTGGAAATTAGTTCAGCGTCTCGTAGAAAAAGAAATTAGCAATCATTTAGA
ACTGAATAATCATATGGGTGAAAACAATGCATATCAACGTTCAAGGCCATATCATTGCACATTAATCGCACAGACAGAAG
AAGGCCTAAAGAATTTATATAAATTAGTATCTAGAGCCCATATTGATTTCTTCTACAGAGTACCAAGATTACCTCGCTCT
GTATTACAAAAGCATCGCGAAGGAATTTTAGTAGGAACGGCTTGTGATAAAGGAGAAGTATTTGAGACGATGATGCAGAA
ATCAGAGGAAGAAGCTGAGCAAGTTGCTGATTTCTATGATTATATTGAAGTACAACCTCCTGAGAACTATACCCATCTTA
TTGAAAAAGATCTGGTTCAAAATGAATCACAAATATTAGATATTTTACGGAAGCTTGTGAACCTTGGAGATAAAATGAAA
AAAACCGTAGTTGCTACTGGTAATGTACATTATCTACATGAACATGATAAGCAGTATCGTCAAATTCTAATTGGTTCGCA
GGCAGGAAATCCATTGAGCCGTCATAAGTTACCAGATACGCCATTCCGTACGACGACTGAAATGATTAACTGTTTTCACT
TCTTAGGCGAGAAAAAAGCAAATGAAATTGTTGTTGATAATACCCAAAAACTAACAGATTCGATTGAGGAAATATCACCG
GTAAAAGATGGATTGTTTACGCCAAATATTGAAGGTGCTGAACAAGAAATGCGTGATTTATGTTATAACAAAGCGAAAGA
GGTATATGGAGAACCTGTCCCGCAAATTGTTGTCGATCGTTTAGAGAAAGAACTTGAAAGTATTATTGGTAATGGATTTG
CGGTTATTTATCTTATCTCGCAAAAACTTGTAAAAAAATCTTTAGATGACGGCTATCTTGTGGGGTCTCGAGGGTCTGTT
GGTTCGTCTTTTGTAGCAACCATGACGGAAATTACAGAAGTAAATCCATTGGTACCGCATTATGTTTGTAAACATTGTCA
TCACCATGAATTTTTTACAGACGGTTCCGTTGCTAGTGGATTTGATTTACCTGATAAAGATTGTCCAGGATGTGGGAAAG
GCTTAACGAAAGATGGACAAGATATTCCATTTGAGACATTTTTAGGATTTAAAGGTGACAAAGTTCCGGATATTGATTTG
AACTTCTCTGGTGATTATCAACCTCGGGCGCATAATTACACGAAAGAGTTGTTTGGTATTGATAATGTATATCGTGCAGG
AACGATAGGAACGGTTGCTGAAAAAACAGCCTATGGCTATGTGAAGGGATACGCTTCAGATAACCAATTTGTGTATAAAA
ATGCAGAAGTGGATCGGCTTGTGCAAGGATGTACAGGAGTAAAACGAACAACAGGACAACACCCTGGTGGAATTATTGTT
GTTCCATCTGATAAAGAGATTTATGATTTTACTCCAATTCAATTTCCTGCTGATGATCGTAATAGTGAATGGAGAACAAC
GCATTTTGATTTCCATTCCATTCATGATAATTTGTTGAAACTTGATATACTTGGACACGATGATCCTACGGTAATACGCA
TGTTGCAAGATTTAAGTGGAATGGATCCAAAAAATATTCCCACGGATGATGAAGAAGTAATGAAAATCTTTTCAGGTACA
GAATCTTTAGGGGTAACTCCGGAACAAATAAATTGTAAAACCGGCACGTTAGGTGTTCCAGAATTTGGTACTAAATTTGT
TCGACAAATGTTGGAAGATACAAAGCCAAAGACCTTCGCAGAGTTACTAATTATTTCTGGATTGTCGCATGGGACGGATG
TGTGGCTTGGAAATGCCCAGGAGTTAATAAATGATGGTATTTGCCAATTACCAGACGTAATTGGGTGCCGTGATGATATT
ATGGTTTATTTGATGCATAAAGGTTTAGACCCATCGATGGCCTTTACCATTATGGAATTTGTTCGTAAAGGAAAAGGGCT
TAAAGATGAATGGATCGACGAGATGAAAAAACACGCTGTACCAGATTGGTATATCGAATCTTGTAAAAAGATCAAGTACA
TGTTCCCGAAAGCACACGCAGCTGCATACGTGTTAATGGCTGTTCGAATCGCTTATTTCAAAGTTCATCACCCAATCCTT
TTTTATGCTGCATACTTTACAGTACGTGCAGATGACTTTGAACTTGATACGATGATCAAGGGCTCTGATGCAATTCGTAA
GCGAATAGAAGAAATCACTGTTAAAGGTAATGACGCCTCACCAAAAGAAAAGAATTTACTTACAGTGCTAGAAATTTCAT
TAGAAATGTGTGAACGAGGATTTTCTTTTAAAAAAGTTGATTTATATCAATCGAGTGCGACCGACTTTATAGTTGAAGGA
GACAGTTTATTACCCCCATTTAATGCTGTGGATGGATTAGGCACAAACGCAGCGTTAAATATAGTGAAAGCAAGAGAAGA
AGGGGAATTCTTGTCTAAGGAAGATTTAAGGGAACGTAGTAAAATTTCGAAGACAGTATTGGAATACTTAGATAACCATG
GGTGCTTAGAAGGAATGGAAGATAAAAACCAGCTATCCTTATTCTAA

Upstream 100 bases:

>100_bases
AAATACAGATCAATGGAATTTATCTTTTGATTAAATACTTCTGTCTCAACCTCTTCCTTTTTGATTCATCTTTTGTTTTG
CATATAGAGGAGGGCAAGAA

Downstream 100 bases:

>100_bases
TACGTGTCAAATAGCATAGTTTTTATATAAACAGGACATCCTATAAACAGATGTTGACTAGATTAACAAATTGTTCTATT
ACACAAGTACTAGAGCAGTT

Product: DNA-directed DNA polymerase III alpha chain

Products: NA

Alternate protein names: PolIII

Number of amino acids: Translated: 1428; Mature: 1428

Protein sequence:

>1428_residues
MDISKKEKLKLLLEQIRMPDNEIEAHFSNSYLDKVEVHKADKKWHFYINIDHVLPFQTYQLFHHSLKESFASIAEVSLTL
SAENRHCPEGDIQIYWKHFIAQTSLSPAYRDLVLDQAPEVSNNKIMLTARNEAEASALKKRLEAKFHDFCLSIGSLPYTL
EVEVKTNTEAMQEFRDKKALEDQQLVMKTVQEKEKRDKDKSVPDQQPLAIGYKIQDEPITMDQIIDEERRITVQGYVFDA
EVRELRSGRSLLIIKATDYTDSIQIKMFSKGDEDAAKFASVKKGMWVKARGSIQTDMYTNELAMMAKDIHEIHVSQRMDD
ASEDKKRVELHTHTTMSQMDAVVSPEALVEQAAKWGHKAIAITDHAGVQGFPDAHNAGKKHGVKVLYGVEANLVDDGVPI
AYNEADRNLYEDTFVVFDVETTGLSAVYDTIIELAAVKIKGGEIVDRFESFANPHHALSQTTIDLTGITDDMVNDAPEVA
DVLKDFHTWMGNDILVAHNASFDMGFLNQGFQRIDYEKASNPVVDTLELARFLLPELRNHRLNTLCKHLDIELTQHHRAI
YDAEATGYLLWKLVQRLVEKEISNHLELNNHMGENNAYQRSRPYHCTLIAQTEEGLKNLYKLVSRAHIDFFYRVPRLPRS
VLQKHREGILVGTACDKGEVFETMMQKSEEEAEQVADFYDYIEVQPPENYTHLIEKDLVQNESQILDILRKLVNLGDKMK
KTVVATGNVHYLHEHDKQYRQILIGSQAGNPLSRHKLPDTPFRTTTEMINCFHFLGEKKANEIVVDNTQKLTDSIEEISP
VKDGLFTPNIEGAEQEMRDLCYNKAKEVYGEPVPQIVVDRLEKELESIIGNGFAVIYLISQKLVKKSLDDGYLVGSRGSV
GSSFVATMTEITEVNPLVPHYVCKHCHHHEFFTDGSVASGFDLPDKDCPGCGKGLTKDGQDIPFETFLGFKGDKVPDIDL
NFSGDYQPRAHNYTKELFGIDNVYRAGTIGTVAEKTAYGYVKGYASDNQFVYKNAEVDRLVQGCTGVKRTTGQHPGGIIV
VPSDKEIYDFTPIQFPADDRNSEWRTTHFDFHSIHDNLLKLDILGHDDPTVIRMLQDLSGMDPKNIPTDDEEVMKIFSGT
ESLGVTPEQINCKTGTLGVPEFGTKFVRQMLEDTKPKTFAELLIISGLSHGTDVWLGNAQELINDGICQLPDVIGCRDDI
MVYLMHKGLDPSMAFTIMEFVRKGKGLKDEWIDEMKKHAVPDWYIESCKKIKYMFPKAHAAAYVLMAVRIAYFKVHHPIL
FYAAYFTVRADDFELDTMIKGSDAIRKRIEEITVKGNDASPKEKNLLTVLEISLEMCERGFSFKKVDLYQSSATDFIVEG
DSLLPPFNAVDGLGTNAALNIVKAREEGEFLSKEDLRERSKISKTVLEYLDNHGCLEGMEDKNQLSLF

Sequences:

>Translated_1428_residues
MDISKKEKLKLLLEQIRMPDNEIEAHFSNSYLDKVEVHKADKKWHFYINIDHVLPFQTYQLFHHSLKESFASIAEVSLTL
SAENRHCPEGDIQIYWKHFIAQTSLSPAYRDLVLDQAPEVSNNKIMLTARNEAEASALKKRLEAKFHDFCLSIGSLPYTL
EVEVKTNTEAMQEFRDKKALEDQQLVMKTVQEKEKRDKDKSVPDQQPLAIGYKIQDEPITMDQIIDEERRITVQGYVFDA
EVRELRSGRSLLIIKATDYTDSIQIKMFSKGDEDAAKFASVKKGMWVKARGSIQTDMYTNELAMMAKDIHEIHVSQRMDD
ASEDKKRVELHTHTTMSQMDAVVSPEALVEQAAKWGHKAIAITDHAGVQGFPDAHNAGKKHGVKVLYGVEANLVDDGVPI
AYNEADRNLYEDTFVVFDVETTGLSAVYDTIIELAAVKIKGGEIVDRFESFANPHHALSQTTIDLTGITDDMVNDAPEVA
DVLKDFHTWMGNDILVAHNASFDMGFLNQGFQRIDYEKASNPVVDTLELARFLLPELRNHRLNTLCKHLDIELTQHHRAI
YDAEATGYLLWKLVQRLVEKEISNHLELNNHMGENNAYQRSRPYHCTLIAQTEEGLKNLYKLVSRAHIDFFYRVPRLPRS
VLQKHREGILVGTACDKGEVFETMMQKSEEEAEQVADFYDYIEVQPPENYTHLIEKDLVQNESQILDILRKLVNLGDKMK
KTVVATGNVHYLHEHDKQYRQILIGSQAGNPLSRHKLPDTPFRTTTEMINCFHFLGEKKANEIVVDNTQKLTDSIEEISP
VKDGLFTPNIEGAEQEMRDLCYNKAKEVYGEPVPQIVVDRLEKELESIIGNGFAVIYLISQKLVKKSLDDGYLVGSRGSV
GSSFVATMTEITEVNPLVPHYVCKHCHHHEFFTDGSVASGFDLPDKDCPGCGKGLTKDGQDIPFETFLGFKGDKVPDIDL
NFSGDYQPRAHNYTKELFGIDNVYRAGTIGTVAEKTAYGYVKGYASDNQFVYKNAEVDRLVQGCTGVKRTTGQHPGGIIV
VPSDKEIYDFTPIQFPADDRNSEWRTTHFDFHSIHDNLLKLDILGHDDPTVIRMLQDLSGMDPKNIPTDDEEVMKIFSGT
ESLGVTPEQINCKTGTLGVPEFGTKFVRQMLEDTKPKTFAELLIISGLSHGTDVWLGNAQELINDGICQLPDVIGCRDDI
MVYLMHKGLDPSMAFTIMEFVRKGKGLKDEWIDEMKKHAVPDWYIESCKKIKYMFPKAHAAAYVLMAVRIAYFKVHHPIL
FYAAYFTVRADDFELDTMIKGSDAIRKRIEEITVKGNDASPKEKNLLTVLEISLEMCERGFSFKKVDLYQSSATDFIVEG
DSLLPPFNAVDGLGTNAALNIVKAREEGEFLSKEDLRERSKISKTVLEYLDNHGCLEGMEDKNQLSLF
>Mature_1428_residues
MDISKKEKLKLLLEQIRMPDNEIEAHFSNSYLDKVEVHKADKKWHFYINIDHVLPFQTYQLFHHSLKESFASIAEVSLTL
SAENRHCPEGDIQIYWKHFIAQTSLSPAYRDLVLDQAPEVSNNKIMLTARNEAEASALKKRLEAKFHDFCLSIGSLPYTL
EVEVKTNTEAMQEFRDKKALEDQQLVMKTVQEKEKRDKDKSVPDQQPLAIGYKIQDEPITMDQIIDEERRITVQGYVFDA
EVRELRSGRSLLIIKATDYTDSIQIKMFSKGDEDAAKFASVKKGMWVKARGSIQTDMYTNELAMMAKDIHEIHVSQRMDD
ASEDKKRVELHTHTTMSQMDAVVSPEALVEQAAKWGHKAIAITDHAGVQGFPDAHNAGKKHGVKVLYGVEANLVDDGVPI
AYNEADRNLYEDTFVVFDVETTGLSAVYDTIIELAAVKIKGGEIVDRFESFANPHHALSQTTIDLTGITDDMVNDAPEVA
DVLKDFHTWMGNDILVAHNASFDMGFLNQGFQRIDYEKASNPVVDTLELARFLLPELRNHRLNTLCKHLDIELTQHHRAI
YDAEATGYLLWKLVQRLVEKEISNHLELNNHMGENNAYQRSRPYHCTLIAQTEEGLKNLYKLVSRAHIDFFYRVPRLPRS
VLQKHREGILVGTACDKGEVFETMMQKSEEEAEQVADFYDYIEVQPPENYTHLIEKDLVQNESQILDILRKLVNLGDKMK
KTVVATGNVHYLHEHDKQYRQILIGSQAGNPLSRHKLPDTPFRTTTEMINCFHFLGEKKANEIVVDNTQKLTDSIEEISP
VKDGLFTPNIEGAEQEMRDLCYNKAKEVYGEPVPQIVVDRLEKELESIIGNGFAVIYLISQKLVKKSLDDGYLVGSRGSV
GSSFVATMTEITEVNPLVPHYVCKHCHHHEFFTDGSVASGFDLPDKDCPGCGKGLTKDGQDIPFETFLGFKGDKVPDIDL
NFSGDYQPRAHNYTKELFGIDNVYRAGTIGTVAEKTAYGYVKGYASDNQFVYKNAEVDRLVQGCTGVKRTTGQHPGGIIV
VPSDKEIYDFTPIQFPADDRNSEWRTTHFDFHSIHDNLLKLDILGHDDPTVIRMLQDLSGMDPKNIPTDDEEVMKIFSGT
ESLGVTPEQINCKTGTLGVPEFGTKFVRQMLEDTKPKTFAELLIISGLSHGTDVWLGNAQELINDGICQLPDVIGCRDDI
MVYLMHKGLDPSMAFTIMEFVRKGKGLKDEWIDEMKKHAVPDWYIESCKKIKYMFPKAHAAAYVLMAVRIAYFKVHHPIL
FYAAYFTVRADDFELDTMIKGSDAIRKRIEEITVKGNDASPKEKNLLTVLEISLEMCERGFSFKKVDLYQSSATDFIVEG
DSLLPPFNAVDGLGTNAALNIVKAREEGEFLSKEDLRERSKISKTVLEYLDNHGCLEGMEDKNQLSLF

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity

COG id: COG2176

COG function: function code L; DNA polymerase III, alpha subunit (gram-positive type)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Escherichia coli, GI1786381, Length=798, Percent_Identity=22.1804511278195, Blast_Score=119, Evalue=1e-27,
Organism=Escherichia coli, GI1786409, Length=162, Percent_Identity=30.8641975308642, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1788149, Length=159, Percent_Identity=30.188679245283, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO3_OCEIH (Q8EQU6)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692514.1
- ProteinModelPortal:   Q8EQU6
- GeneID:   1017981
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1593
- NMPDR:   fig|221109.1.peg.1595
- HOGENOM:   HBG617116
- OMA:   WKTTHFD
- BioCyc:   OIHE221109:OB1593-MONOMER
- BRENDA:   2.7.7.7
- GO:   GO:0005737
- HAMAP:   MF_00356
- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR006308
- InterPro:   IPR012337
- SMART:   SM00479
- SMART:   SM00481
- TIGRFAMs:   TIGR00573
- TIGRFAMs:   TIGR01405

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB; SSF89550 PHP-like; SSF53098 RNaseH_fold

EC number: =2.7.7.7

Molecular weight: Translated: 161815; Mature: 161815

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDISKKEKLKLLLEQIRMPDNEIEAHFSNSYLDKVEVHKADKKWHFYINIDHVLPFQTYQ
CCCCHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHEECCCEEEEEEEECCCCCHHHHH
LFHHSLKESFASIAEVSLTLSAENRHCPEGDIQIYWKHFIAQTSLSPAYRDLVLDQAPEV
HHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
SNNKIMLTARNEAEASALKKRLEAKFHDFCLSIGSLPYTLEVEVKTNTEAMQEFRDKKAL
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHCC
EDQQLVMKTVQEKEKRDKDKSVPDQQPLAIGYKIQDEPITMDQIIDEERRITVQGYVFDA
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHCCCCEEEEEEEEECH
EVRELRSGRSLLIIKATDYTDSIQIKMFSKGDEDAAKFASVKKGMWVKARGSIQTDMYTN
HHHHHHCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEECCCEECHHHHH
ELAMMAKDIHEIHVSQRMDDASEDKKRVELHTHTTMSQMDAVVSPEALVEQAAKWGHKAI
HHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEHHHHHHHHHHHCCHHHHHHHHHHCCCCEE
AITDHAGVQGFPDAHNAGKKHGVKVLYGVEANLVDDGVPIAYNEADRNLYEDTFVVFDVE
EEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCEEEEEEEC
TTGLSAVYDTIIELAAVKIKGGEIVDRFESFANPHHALSQTTIDLTGITDDMVNDAPEVA
CCCHHHHHHHHHHHHHEEECCCHHHHHHHHHCCHHHHHHCCEEEEECCCHHHHCCCHHHH
DVLKDFHTWMGNDILVAHNASFDMGFLNQGFQRIDYEKASNPVVDTLELARFLLPELRNH
HHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHCC
RLNTLCKHLDIELTQHHRAIYDAEATGYLLWKLVQRLVEKEISNHLELNNHMGENNAYQR
HHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SRPYHCTLIAQTEEGLKNLYKLVSRAHIDFFYRVPRLPRSVLQKHREGILVGTACDKGEV
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEECCCCHHH
FETMMQKSEEEAEQVADFYDYIEVQPPENYTHLIEKDLVQNESQILDILRKLVNLGDKMK
HHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHH
KTVVATGNVHYLHEHDKQYRQILIGSQAGNPLSRHKLPDTPFRTTTEMINCFHFLGEKKA
HEEEECCCEEEEHHHHHHHHHHEEECCCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCC
NEIVVDNTQKLTDSIEEISPVKDGLFTPNIEGAEQEMRDLCYNKAKEVYGEPVPQIVVDR
CCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LEKELESIIGNGFAVIYLISQKLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLVPH
HHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCHHH
YVCKHCHHHEFFTDGSVASGFDLPDKDCPGCGKGLTKDGQDIPFETFLGFKGDKVPDIDL
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCEEE
NFSGDYQPRAHNYTKELFGIDNVYRAGTIGTVAEKTAYGYVKGYASDNQFVYKNAEVDRL
CCCCCCCCCHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHEEEEECCCCEEEEECCCHHHH
VQGCTGVKRTTGQHPGGIIVVPSDKEIYDFTPIQFPADDRNSEWRTTHFDFHSIHDNLLK
HHHCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCEEEECCHHHHCCCEEE
LDILGHDDPTVIRMLQDLSGMDPKNIPTDDEEVMKIFSGTESLGVTPEQINCKTGTLGVP
EEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCC
EFGTKFVRQMLEDTKPKTFAELLIISGLSHGTDVWLGNAQELINDGICQLPDVIGCRDDI
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEECCHHHHHCCCCHHCCHHHCCHHHH
MVYLMHKGLDPSMAFTIMEFVRKGKGLKDEWIDEMKKHAVPDWYIESCKKIKYMFPKAHA
HHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHH
AAYVLMAVRIAYFKVHHPILFYAAYFTVRADDFELDTMIKGSDAIRKRIEEITVKGNDAS
HHHHHHHHHHHHHHHHCHHHEEEHHHEEECCCCEEHHEECCCHHHHHHHHHEEECCCCCC
PKEKNLLTVLEISLEMCERGFSFKKVDLYQSSATDFIVEGDSLLPPFNAVDGLGTNAALN
CCHHCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEECCCCCCCCHHHCCCCCCHHEE
IVKAREEGEFLSKEDLRERSKISKTVLEYLDNHGCLEGMEDKNQLSLF
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDISKKEKLKLLLEQIRMPDNEIEAHFSNSYLDKVEVHKADKKWHFYINIDHVLPFQTYQ
CCCCHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHEECCCEEEEEEEECCCCCHHHHH
LFHHSLKESFASIAEVSLTLSAENRHCPEGDIQIYWKHFIAQTSLSPAYRDLVLDQAPEV
HHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
SNNKIMLTARNEAEASALKKRLEAKFHDFCLSIGSLPYTLEVEVKTNTEAMQEFRDKKAL
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHCC
EDQQLVMKTVQEKEKRDKDKSVPDQQPLAIGYKIQDEPITMDQIIDEERRITVQGYVFDA
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHCCCCEEEEEEEEECH
EVRELRSGRSLLIIKATDYTDSIQIKMFSKGDEDAAKFASVKKGMWVKARGSIQTDMYTN
HHHHHHCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEECCCEECHHHHH
ELAMMAKDIHEIHVSQRMDDASEDKKRVELHTHTTMSQMDAVVSPEALVEQAAKWGHKAI
HHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEHHHHHHHHHHHCCHHHHHHHHHHCCCCEE
AITDHAGVQGFPDAHNAGKKHGVKVLYGVEANLVDDGVPIAYNEADRNLYEDTFVVFDVE
EEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCEEEEEEEC
TTGLSAVYDTIIELAAVKIKGGEIVDRFESFANPHHALSQTTIDLTGITDDMVNDAPEVA
CCCHHHHHHHHHHHHHEEECCCHHHHHHHHHCCHHHHHHCCEEEEECCCHHHHCCCHHHH
DVLKDFHTWMGNDILVAHNASFDMGFLNQGFQRIDYEKASNPVVDTLELARFLLPELRNH
HHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHCC
RLNTLCKHLDIELTQHHRAIYDAEATGYLLWKLVQRLVEKEISNHLELNNHMGENNAYQR
HHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SRPYHCTLIAQTEEGLKNLYKLVSRAHIDFFYRVPRLPRSVLQKHREGILVGTACDKGEV
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEECCCCHHH
FETMMQKSEEEAEQVADFYDYIEVQPPENYTHLIEKDLVQNESQILDILRKLVNLGDKMK
HHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHH
KTVVATGNVHYLHEHDKQYRQILIGSQAGNPLSRHKLPDTPFRTTTEMINCFHFLGEKKA
HEEEECCCEEEEHHHHHHHHHHEEECCCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCC
NEIVVDNTQKLTDSIEEISPVKDGLFTPNIEGAEQEMRDLCYNKAKEVYGEPVPQIVVDR
CCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LEKELESIIGNGFAVIYLISQKLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLVPH
HHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCHHH
YVCKHCHHHEFFTDGSVASGFDLPDKDCPGCGKGLTKDGQDIPFETFLGFKGDKVPDIDL
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCEEE
NFSGDYQPRAHNYTKELFGIDNVYRAGTIGTVAEKTAYGYVKGYASDNQFVYKNAEVDRL
CCCCCCCCCHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHEEEEECCCCEEEEECCCHHHH
VQGCTGVKRTTGQHPGGIIVVPSDKEIYDFTPIQFPADDRNSEWRTTHFDFHSIHDNLLK
HHHCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCEEEECCHHHHCCCEEE
LDILGHDDPTVIRMLQDLSGMDPKNIPTDDEEVMKIFSGTESLGVTPEQINCKTGTLGVP
EEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCC
EFGTKFVRQMLEDTKPKTFAELLIISGLSHGTDVWLGNAQELINDGICQLPDVIGCRDDI
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEECCHHHHHCCCCHHCCHHHCCHHHH
MVYLMHKGLDPSMAFTIMEFVRKGKGLKDEWIDEMKKHAVPDWYIESCKKIKYMFPKAHA
HHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHH
AAYVLMAVRIAYFKVHHPILFYAAYFTVRADDFELDTMIKGSDAIRKRIEEITVKGNDAS
HHHHHHHHHHHHHHHHCHHHEEEHHHEEECCCCEEHHEECCCHHHHHHHHHEEECCCCCC
PKEKNLLTVLEISLEMCERGFSFKKVDLYQSSATDFIVEGDSLLPPFNAVDGLGTNAALN
CCHHCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEECCCCCCCCHHHCCCCCCHHEE
IVKAREEGEFLSKEDLRERSKISKTVLEYLDNHGCLEGMEDKNQLSLF
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376