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The map label for this gene is frr

Identifier: 23099044

GI number: 23099044

Start: 1625207

End: 1625764

Strand: Direct

Name: frr

Synonym: OB1589

Alternate gene names: 23099044

Gene position: 1625207-1625764 (Clockwise)

Preceding gene: 23099043

Following gene: 23099045

Centisome position: 44.77

GC content: 35.3

Gene sequence:

>558_bases
ATGTCAGCTTCTGAATTAAAAGAAATGGAACAAAAGATGGAACAAGCGGTACAAGCTCTTTCTAAGAATTTAGCTTCCGT
AAGAGCAGGACGTGCTAACCCAAGTATTTTAGATAGTGTATTTGTAGATTATTATGGTGCTTCTACACCTTTAAACCAAT
TAGCATCAGTTGGAGCTCCTGAAGCAAGACTTCTAACGATTACACCATATGATAAGTCTGCAATCGGTGATATCGAAAAA
GCAATTCAAAAAGCAGACCTCGGCCTATCTCCTTCCAGTGATGGTAATATTATTCGAATTAACATTCCAGCTCTTACGCA
AGAACGACGTAAAGACCTTGTTAAAGTGGTTGGAAAGTACTCAGAAGAAGCAAAAGTTCAAATTCGTAATATCCGTCGAG
ATACAAACGACCAGTTGAAAAAAATGGAGAAAAATGGTGACTTAACAGAAGATGATCTTCGAGGATTCCAAGATGATGTT
CAAACTTCTACGAATGACTATATTAATAAAATTGATCAATTAGCTAAAAATAAAGAAAATGAAATTATGGAAGTTTAA

Upstream 100 bases:

>100_bases
ATAACATTCCATTAATTGTATTCTCAATTATGGAAGAAGGAAACATTAAACGGGTCGTTCAAGGTGAGACGATCGGAACT
ACAATAAGGGGGAAATAAAA

Downstream 100 bases:

>100_bases
TTACATTCTCTAATCAGTTCTTTAATGGTTTATCGTTGCTGATTACAGAGGATTTCCATTAAATGTACTGCATTTTGTAA
ATTATTATTTAAAAATCGAT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSASELKEMEQKMEQAVQALSKNLASVRAGRANPSILDSVFVDYYGASTPLNQLASVGAPEARLLTITPYDKSAIGDIEK
AIQKADLGLSPSSDGNIIRINIPALTQERRKDLVKVVGKYSEEAKVQIRNIRRDTNDQLKKMEKNGDLTEDDLRGFQDDV
QTSTNDYINKIDQLAKNKENEIMEV

Sequences:

>Translated_185_residues
MSASELKEMEQKMEQAVQALSKNLASVRAGRANPSILDSVFVDYYGASTPLNQLASVGAPEARLLTITPYDKSAIGDIEK
AIQKADLGLSPSSDGNIIRINIPALTQERRKDLVKVVGKYSEEAKVQIRNIRRDTNDQLKKMEKNGDLTEDDLRGFQDDV
QTSTNDYINKIDQLAKNKENEIMEV
>Mature_184_residues
SASELKEMEQKMEQAVQALSKNLASVRAGRANPSILDSVFVDYYGASTPLNQLASVGAPEARLLTITPYDKSAIGDIEKA
IQKADLGLSPSSDGNIIRINIPALTQERRKDLVKVVGKYSEEAKVQIRNIRRDTNDQLKKMEKNGDLTEDDLRGFQDDVQ
TSTNDYINKIDQLAKNKENEIMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1786368, Length=178, Percent_Identity=46.6292134831461, Blast_Score=169, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24661488, Length=178, Percent_Identity=24.7191011235955, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_OCEIH (Q8EQV0)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692510.1
- ProteinModelPortal:   Q8EQV0
- SMR:   Q8EQV0
- GeneID:   1017977
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1589
- NMPDR:   fig|221109.1.peg.1591
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- BioCyc:   OIHE221109:OB1589-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20571; Mature: 20440

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASELKEMEQKMEQAVQALSKNLASVRAGRANPSILDSVFVDYYGASTPLNQLASVGAP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCC
EARLLTITPYDKSAIGDIEKAIQKADLGLSPSSDGNIIRINIPALTQERRKDLVKVVGKY
CCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHC
SEEAKVQIRNIRRDTNDQLKKMEKNGDLTEDDLRGFQDDVQTSTNDYINKIDQLAKNKEN
CHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCH
EIMEV
HHCCC
>Mature Secondary Structure 
SASELKEMEQKMEQAVQALSKNLASVRAGRANPSILDSVFVDYYGASTPLNQLASVGAP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCC
EARLLTITPYDKSAIGDIEKAIQKADLGLSPSSDGNIIRINIPALTQERRKDLVKVVGKY
CCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHC
SEEAKVQIRNIRRDTNDQLKKMEKNGDLTEDDLRGFQDDVQTSTNDYINKIDQLAKNKEN
CHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCH
EIMEV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376