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The map label for this gene is hslV

Identifier: 23099004

GI number: 23099004

Start: 1592676

End: 1593221

Strand: Direct

Name: hslV

Synonym: OB1549

Alternate gene names: 23099004

Gene position: 1592676-1593221 (Clockwise)

Preceding gene: 23099003

Following gene: 23099005

Centisome position: 43.87

GC content: 39.19

Gene sequence:

>546_bases
ATGACAATGGAAATGCATGCAACAACTATTTTTGCTGTGCAACACCAAGGTCAAAGTGCCATGTGTGGAGACGGTCAAGT
AACATTGGGAAATTCCGTCGTAATGAAGCACAAGGCGAAAAAAGTTCGAACGCTCTATAATGGAAAAGTTCTTGCAGGGT
TTGCTGGTTCGGTAGCGGATGCGTTTACCTTGTTCGAAAAATTTGAAACTAAGTTACAATCATTTAATGGTAATTTAACA
AGAGCTTCGGTAGAACTAGCTCAAGAATGGCGCTCAGATAAAGTACTTCGTAAATTAGAAGCAATGTTAATTGTGATGAA
TAAAGAACATATGTATTTGGTATCTGGAACTGGTGAAGTGATTGAACCTGATGATGGTATATTAGCTATTGGGTCAGGTG
GGAATTATGCTTTAAGTGCTGGAAGGGCGCTTGTCAGATATGCTGACAATATGTCAGCTGCGGATATAGCCCGTTCGGCA
TTAGAAGTTGCAGGAGAAATATGTGTGTTCACTAATGATCAAATAACCTTAGAAGTACTTGAATAA

Upstream 100 bases:

>100_bases
TCGACACAAATATATACACATGTGACAAAAGACCATTTGCGGGAAGCTTATATGAAAAGCCACCCAAGAGCAAATGGCAA
CAAAAGCTGAGGTGAGGGTA

Downstream 100 bases:

>100_bases
AAGGAGGCTATCCATTAATGGGAATGGATTATACCCCAAGGCAAATTGTTGAGCAGTTAGACCAGTTTATTGTTGGTCAA
AAGCAAGCAAAAAAATCAGT

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MTMEMHATTIFAVQHQGQSAMCGDGQVTLGNSVVMKHKAKKVRTLYNGKVLAGFAGSVADAFTLFEKFETKLQSFNGNLT
RASVELAQEWRSDKVLRKLEAMLIVMNKEHMYLVSGTGEVIEPDDGILAIGSGGNYALSAGRALVRYADNMSAADIARSA
LEVAGEICVFTNDQITLEVLE

Sequences:

>Translated_181_residues
MTMEMHATTIFAVQHQGQSAMCGDGQVTLGNSVVMKHKAKKVRTLYNGKVLAGFAGSVADAFTLFEKFETKLQSFNGNLT
RASVELAQEWRSDKVLRKLEAMLIVMNKEHMYLVSGTGEVIEPDDGILAIGSGGNYALSAGRALVRYADNMSAADIARSA
LEVAGEICVFTNDQITLEVLE
>Mature_180_residues
TMEMHATTIFAVQHQGQSAMCGDGQVTLGNSVVMKHKAKKVRTLYNGKVLAGFAGSVADAFTLFEKFETKLQSFNGNLTR
ASVELAQEWRSDKVLRKLEAMLIVMNKEHMYLVSGTGEVIEPDDGILAIGSGGNYALSAGRALVRYADNMSAADIARSAL
EVAGEICVFTNDQITLEVLE

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=173, Percent_Identity=52.6011560693642, Blast_Score=184, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_OCEIH (Q8CXH2)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692470.1
- ProteinModelPortal:   Q8CXH2
- SMR:   Q8CXH2
- MEROPS:   T01.007
- GeneID:   1017835
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1549
- NMPDR:   fig|221109.1.peg.1551
- HOGENOM:   HBG288822
- OMA:   AADICVY
- ProtClustDB:   PRK05456
- BioCyc:   OIHE221109:OB1549-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 19595; Mature: 19464

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: ACT_SITE 8-8

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMEMHATTIFAVQHQGQSAMCGDGQVTLGNSVVMKHKAKKVRTLYNGKVLAGFAGSVAD
CCEEEEEEEEEEEEECCCCCCCCCCCEEECCCEEEHHHHHHHHHHHCCEEEECCCCHHHH
AFTLFEKFETKLQSFNGNLTRASVELAQEWRSDKVLRKLEAMLIVMNKEHMYLVSGTGEV
HHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCHHHHHHHHHHEEEEECCCEEEEEECCCCE
IEPDDGILAIGSGGNYALSAGRALVRYADNMSAADIARSALEVAGEICVFTNDQITLEVL
ECCCCCEEEEECCCCEEECCCCEEEHHHCCCCHHHHHHHHHHHCCCEEEEECCEEEEEEE
E
C
>Mature Secondary Structure 
TMEMHATTIFAVQHQGQSAMCGDGQVTLGNSVVMKHKAKKVRTLYNGKVLAGFAGSVAD
CEEEEEEEEEEEEECCCCCCCCCCCEEECCCEEEHHHHHHHHHHHCCEEEECCCCHHHH
AFTLFEKFETKLQSFNGNLTRASVELAQEWRSDKVLRKLEAMLIVMNKEHMYLVSGTGEV
HHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCHHHHHHHHHHEEEEECCCEEEEEECCCCE
IEPDDGILAIGSGGNYALSAGRALVRYADNMSAADIARSALEVAGEICVFTNDQITLEVL
ECCCCCEEEEECCCCEEECCCCEEEHHHCCCCHHHHHHHHHHHCCCEEEEECCEEEEEEE
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376