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The map label for this gene is xerC

Identifier: 23099003

GI number: 23099003

Start: 1591748

End: 1592665

Strand: Direct

Name: xerC

Synonym: OB1548

Alternate gene names: 23099003

Gene position: 1591748-1592665 (Clockwise)

Preceding gene: 23099002

Following gene: 23099004

Centisome position: 43.84

GC content: 37.69

Gene sequence:

>918_bases
ATGAACCAATTAGAATTATATATAGATACATTTGTGGAATATCTGCAAATAGAAAAAAACGCTTCACCTTATACCGTGAA
ATATTATCGGAATGATCTGGAAATTTTCGCGGATTTCCTCCGTTCAGAGGGGTTATCACATATTGCGAATGTGACATATA
AAGATGTACGCATTTTTCTAACTTCTTTATATGAGCAAGAACTTAGTCGTAGGTCCGTTTCAAGAAAGATATCAACCTTA
AGAAGTTTTTACCGTTTTCTAGAACGAGAAGGTTATGTAGAAGGAAACCCTTTTGTACAGTTACATCTACCGAAAACAAG
TAAACCGGTTCCTGGTTTCCTATATCAAGAGGAATTGGATAAATTGTTTGAAGTTAACGATATAACGACTCCATTAGGGC
AAAGAGATCAAGCTTTATTAGAGATGTTATATGGAACTGGAATTCGTGTCAGTGAATGTCAAAACCTGCGTTTACAAGAT
ATTGACTTTGCAATAGGTACTATCTTCGTTCGAGGGAAGGGACGTAAGGAACGTTACGTGCCGTTTGGAAGTTTTGCTGA
AATAGCGTTAGAGACCTATCTTCAGGAAGGAAGAACTAAGTTACTGGAAAAAAGTAACTCAGACACGGAATTTATTTTCT
TAAATTCCCGTGGAGGACATCTAACCAATCGAGGAATTCGTACCATTTTAAATAAAATCGTCGAAAGAGCCTCTTTGACT
GTACATGTACATCCTCATAAGTTGAGACATACATTTGCAACGCATCTATTAAATGAGGGTGCTGATCTTAGATCCGTACA
GGAGTTGCTCGGCCATGAAAGCCTATCCTCGACACAAATATATACACATGTGACAAAAGACCATTTGCGGGAAGCTTATA
TGAAAAGCCACCCAAGAGCAAATGGCAACAAAAGCTGA

Upstream 100 bases:

>100_bases
GATTGTATATCATTCTGAATTTTGTTACAATTTAGTTAAGTTCATTGCTTTATCGGTTAGAGTGTGTTATTATTTATTCG
CTGTGCAATGAGGTGAAGGT

Downstream 100 bases:

>100_bases
GGTGAGGGTAATGACAATGGAAATGCATGCAACAACTATTTTTGCTGTGCAACACCAAGGTCAAAGTGCCATGTGTGGAG
ACGGTCAAGTAACATTGGGA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNQLELYIDTFVEYLQIEKNASPYTVKYYRNDLEIFADFLRSEGLSHIANVTYKDVRIFLTSLYEQELSRRSVSRKISTL
RSFYRFLEREGYVEGNPFVQLHLPKTSKPVPGFLYQEELDKLFEVNDITTPLGQRDQALLEMLYGTGIRVSECQNLRLQD
IDFAIGTIFVRGKGRKERYVPFGSFAEIALETYLQEGRTKLLEKSNSDTEFIFLNSRGGHLTNRGIRTILNKIVERASLT
VHVHPHKLRHTFATHLLNEGADLRSVQELLGHESLSSTQIYTHVTKDHLREAYMKSHPRANGNKS

Sequences:

>Translated_305_residues
MNQLELYIDTFVEYLQIEKNASPYTVKYYRNDLEIFADFLRSEGLSHIANVTYKDVRIFLTSLYEQELSRRSVSRKISTL
RSFYRFLEREGYVEGNPFVQLHLPKTSKPVPGFLYQEELDKLFEVNDITTPLGQRDQALLEMLYGTGIRVSECQNLRLQD
IDFAIGTIFVRGKGRKERYVPFGSFAEIALETYLQEGRTKLLEKSNSDTEFIFLNSRGGHLTNRGIRTILNKIVERASLT
VHVHPHKLRHTFATHLLNEGADLRSVQELLGHESLSSTQIYTHVTKDHLREAYMKSHPRANGNKS
>Mature_305_residues
MNQLELYIDTFVEYLQIEKNASPYTVKYYRNDLEIFADFLRSEGLSHIANVTYKDVRIFLTSLYEQELSRRSVSRKISTL
RSFYRFLEREGYVEGNPFVQLHLPKTSKPVPGFLYQEELDKLFEVNDITTPLGQRDQALLEMLYGTGIRVSECQNLRLQD
IDFAIGTIFVRGKGRKERYVPFGSFAEIALETYLQEGRTKLLEKSNSDTEFIFLNSRGGHLTNRGIRTILNKIVERASLT
VHVHPHKLRHTFATHLLNEGADLRSVQELLGHESLSSTQIYTHVTKDHLREAYMKSHPRANGNKS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1789261, Length=297, Percent_Identity=40.0673400673401, Blast_Score=203, Evalue=9e-54,
Organism=Escherichia coli, GI1790244, Length=304, Percent_Identity=35.5263157894737, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI1790767, Length=171, Percent_Identity=30.4093567251462, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790768, Length=152, Percent_Identity=33.5526315789474, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_OCEIH (Q7ZAM5)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692469.1
- ProteinModelPortal:   Q7ZAM5
- SMR:   Q7ZAM5
- GeneID:   1017834
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1548
- NMPDR:   fig|221109.1.peg.1550
- HOGENOM:   HBG727654
- OMA:   YSQYTIV
- ProtClustDB:   PRK00236
- BioCyc:   OIHE221109:OB1548-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02224

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 35338; Mature: 35338

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: ACT_SITE 149-149 ACT_SITE 173-173 ACT_SITE 246-246 ACT_SITE 249-249 ACT_SITE 272-272 ACT_SITE 281-281

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLELYIDTFVEYLQIEKNASPYTVKYYRNDLEIFADFLRSEGLSHIANVTYKDVRIFL
CCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TSLYEQELSRRSVSRKISTLRSFYRFLEREGYVEGNPFVQLHLPKTSKPVPGFLYQEELD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHH
KLFEVNDITTPLGQRDQALLEMLYGTGIRVSECQNLRLQDIDFAIGTIFVRGKGRKERYV
HHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCHHHHHEEEEEEEEECCCCCCCCC
PFGSFAEIALETYLQEGRTKLLEKSNSDTEFIFLNSRGGHLTNRGIRTILNKIVERASLT
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCEE
VHVHPHKLRHTFATHLLNEGADLRSVQELLGHESLSSTQIYTHVTKDHLREAYMKSHPRA
EEECHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
NGNKS
CCCCC
>Mature Secondary Structure
MNQLELYIDTFVEYLQIEKNASPYTVKYYRNDLEIFADFLRSEGLSHIANVTYKDVRIFL
CCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TSLYEQELSRRSVSRKISTLRSFYRFLEREGYVEGNPFVQLHLPKTSKPVPGFLYQEELD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHH
KLFEVNDITTPLGQRDQALLEMLYGTGIRVSECQNLRLQDIDFAIGTIFVRGKGRKERYV
HHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCHHHHHEEEEEEEEECCCCCCCCC
PFGSFAEIALETYLQEGRTKLLEKSNSDTEFIFLNSRGGHLTNRGIRTILNKIVERASLT
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCEE
VHVHPHKLRHTFATHLLNEGADLRSVQELLGHESLSSTQIYTHVTKDHLREAYMKSHPRA
EEECHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
NGNKS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376