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The map label for this gene is nprA [H]

Identifier: 23098763

GI number: 23098763

Start: 1352393

End: 1353673

Strand: Reverse

Name: nprA [H]

Synonym: OB1308

Alternate gene names: 23098763

Gene position: 1353673-1352393 (Counterclockwise)

Preceding gene: 23098765

Following gene: 23098753

Centisome position: 37.29

GC content: 31.77

Gene sequence:

>1281_bases
TTGGATACTAAAATTGGGCAGATTATAAAGCACTATCGATTAAAAGCTAATATGACCCAAGCAGACCTTGCAGATGGACT
GATTTCCGTTTCATATTTGTCTAAGATCGAAAACGGCAATCAAATACCTCCTGGGGACATAGCTGAACTCCTTAGCCAAC
GGTTAGATATACCAGTGGAATTAATGCACCAAAGTAAGGATAAATACGATAAGTTAGTTGAAAAATGGATTGGTTATTTA
CTTGAAGAAGACGTAGATAGTGCAGTTAATATATACGAAAATAGTATTAAACAAATACTTGAAATCACTAATTCTACAAT
TGATATTCCCATTGAATTACACAAATTCAGGTACTTCTTGTTATTACACGACCTGAATCAAGCAATGCAACAACATCAGC
ATCTAAACATGCAATCCAAAAAATTTAATAAAATGGAATTATACTATTGGTATAAATACTCAGGAATTTTTTGGAATGCA
CAAGAATATCACCGTCGTGCTTTACAATTATTTTTAAAAGCAGAAAAGCATATAGATGAATTCGTCCTTCACGAACAAAA
AGAGCAAACAGATTTATACTATCGTTTGGCTTCAGCAGCTTCTGCTTCAAATGATTTGCACAACGTTTATCAATACAATA
AAAAAGCATTAAATCTATTTCGTAGCCGTTATTTATTAGAGGAATGTTCCGAATCTCATTTATTATTTTCCAAATATTTT
AGGCAAATACATGATTATACTCAAGCATGGAAATGTACCGAAATTGCTGAGGATATTGCCAGTAAAATCAATTGCCCCAC
TCTACTCGCTAAATGTAATGAAAGCTATGGTTCCATCGAAGTTGATCAACAACATTATCAAGCAGGTATTAGTTACTTAT
TAAAAAGCTATGAACTTTGTATCCATTGTACTATGGAACAAAAAATTGGACTTATACTCAAAATTATTAAAGTCTATTAC
TATCAGAATAGCCATGCTGAGGTTCGTAAATGGCTAGATCAAGTATTAATTACCGTACAAGAATGTTACGGAAATGACAT
TAATAAATTAACACTTGATATCAAAATGTTAGAGCATCGGATTAACCAGACAAATCCCTTTGCACTTGAATCTTTTATAA
AGAAAGATATCATCCCTTATTTCGAGGAAAGGTCCTCATATAATGAATTACAACTATACCTACGACAATTAGCAGATGCT
TATTATTATCATGAACAATTTCAGTTAGCTGCTTATTATTATCAAAAATCCTTAAAAACAGATAATTACTTACCAATTTG
A

Upstream 100 bases:

>100_bases
AAGAATTAAGTATTTTTATATATTTTACGTCAATAAATTATACTCTATGTTAGTATTTCAACGGCATCCCTTATATAATA
AAAACAGGAGGTGTTAAAAT

Downstream 100 bases:

>100_bases
GAATACTCAATAGAGAAATTAAGAAGTAAAAGAAGATTAGACATAACAAACGGTATTTTCTAAATGACGGATGATAGCTA
GAATTATCATAAGTTATGTA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MDTKIGQIIKHYRLKANMTQADLADGLISVSYLSKIENGNQIPPGDIAELLSQRLDIPVELMHQSKDKYDKLVEKWIGYL
LEEDVDSAVNIYENSIKQILEITNSTIDIPIELHKFRYFLLLHDLNQAMQQHQHLNMQSKKFNKMELYYWYKYSGIFWNA
QEYHRRALQLFLKAEKHIDEFVLHEQKEQTDLYYRLASAASASNDLHNVYQYNKKALNLFRSRYLLEECSESHLLFSKYF
RQIHDYTQAWKCTEIAEDIASKINCPTLLAKCNESYGSIEVDQQHYQAGISYLLKSYELCIHCTMEQKIGLILKIIKVYY
YQNSHAEVRKWLDQVLITVQECYGNDINKLTLDIKMLEHRINQTNPFALESFIKKDIIPYFEERSSYNELQLYLRQLADA
YYYHEQFQLAAYYYQKSLKTDNYLPI

Sequences:

>Translated_426_residues
MDTKIGQIIKHYRLKANMTQADLADGLISVSYLSKIENGNQIPPGDIAELLSQRLDIPVELMHQSKDKYDKLVEKWIGYL
LEEDVDSAVNIYENSIKQILEITNSTIDIPIELHKFRYFLLLHDLNQAMQQHQHLNMQSKKFNKMELYYWYKYSGIFWNA
QEYHRRALQLFLKAEKHIDEFVLHEQKEQTDLYYRLASAASASNDLHNVYQYNKKALNLFRSRYLLEECSESHLLFSKYF
RQIHDYTQAWKCTEIAEDIASKINCPTLLAKCNESYGSIEVDQQHYQAGISYLLKSYELCIHCTMEQKIGLILKIIKVYY
YQNSHAEVRKWLDQVLITVQECYGNDINKLTLDIKMLEHRINQTNPFALESFIKKDIIPYFEERSSYNELQLYLRQLADA
YYYHEQFQLAAYYYQKSLKTDNYLPI
>Mature_426_residues
MDTKIGQIIKHYRLKANMTQADLADGLISVSYLSKIENGNQIPPGDIAELLSQRLDIPVELMHQSKDKYDKLVEKWIGYL
LEEDVDSAVNIYENSIKQILEITNSTIDIPIELHKFRYFLLLHDLNQAMQQHQHLNMQSKKFNKMELYYWYKYSGIFWNA
QEYHRRALQLFLKAEKHIDEFVLHEQKEQTDLYYRLASAASASNDLHNVYQYNKKALNLFRSRYLLEECSESHLLFSKYF
RQIHDYTQAWKCTEIAEDIASKINCPTLLAKCNESYGSIEVDQQHYQAGISYLLKSYELCIHCTMEQKIGLILKIIKVYY
YQNSHAEVRKWLDQVLITVQECYGNDINKLTLDIKMLEHRINQTNPFALESFIKKDIIPYFEERSSYNELQLYLRQLADA
YYYHEQFQLAAYYYQKSLKTDNYLPI

Specific function: Activates the transcription of nprS by about five fold. May bind to the upstream region of nprS promoter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001387
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01381 HTH_3; PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 50654; Mature: 50654

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTKIGQIIKHYRLKANMTQADLADGLISVSYLSKIENGNQIPPGDIAELLSQRLDIPVE
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHH
LMHQSKDKYDKLVEKWIGYLLEEDVDSAVNIYENSIKQILEITNSTIDIPIELHKFRYFL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHH
LLHDLNQAMQQHQHLNMQSKKFNKMELYYWYKYSGIFWNAQEYHRRALQLFLKAEKHIDE
HHHHHHHHHHHHHHCCCHHHCCCCEEEEEEEEECCEEECHHHHHHHHHHHHHHHHHHHHH
FVLHEQKEQTDLYYRLASAASASNDLHNVYQYNKKALNLFRSRYLLEECSESHLLFSKYF
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RQIHDYTQAWKCTEIAEDIASKINCPTLLAKCNESYGSIEVDQQHYQAGISYLLKSYELC
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHH
IHCTMEQKIGLILKIIKVYYYQNSHAEVRKWLDQVLITVQECYGNDINKLTLDIKMLEHR
HEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
INQTNPFALESFIKKDIIPYFEERSSYNELQLYLRQLADAYYYHEQFQLAAYYYQKSLKT
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DNYLPI
CCCCCC
>Mature Secondary Structure
MDTKIGQIIKHYRLKANMTQADLADGLISVSYLSKIENGNQIPPGDIAELLSQRLDIPVE
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHH
LMHQSKDKYDKLVEKWIGYLLEEDVDSAVNIYENSIKQILEITNSTIDIPIELHKFRYFL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHH
LLHDLNQAMQQHQHLNMQSKKFNKMELYYWYKYSGIFWNAQEYHRRALQLFLKAEKHIDE
HHHHHHHHHHHHHHCCCHHHCCCCEEEEEEEEECCEEECHHHHHHHHHHHHHHHHHHHHH
FVLHEQKEQTDLYYRLASAASASNDLHNVYQYNKKALNLFRSRYLLEECSESHLLFSKYF
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RQIHDYTQAWKCTEIAEDIASKINCPTLLAKCNESYGSIEVDQQHYQAGISYLLKSYELC
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHH
IHCTMEQKIGLILKIIKVYYYQNSHAEVRKWLDQVLITVQECYGNDINKLTLDIKMLEHR
HEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
INQTNPFALESFIKKDIIPYFEERSSYNELQLYLRQLADAYYYHEQFQLAAYYYQKSLKT
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DNYLPI
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2203733 [H]