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The map label for this gene is argJ

Identifier: 23098531

GI number: 23098531

Start: 1119226

End: 1120449

Strand: Direct

Name: argJ

Synonym: OB1076

Alternate gene names: 23098531

Gene position: 1119226-1120449 (Clockwise)

Preceding gene: 23098530

Following gene: 23098532

Centisome position: 30.83

GC content: 39.46

Gene sequence:

>1224_bases
ATGGAAACGACCACAGTGAAAGAAATATCAATATTAAAAAATGGTCATGTGACGAGTCCATCAGGGTTCTATGCTGGCGG
GGTGCATTGTGGGCTACGACGAAAAAAACTTGATTTAGGCTGGATCTATTCCGATACTCCTGCAAGTGCAGCCGGTGTTT
ATACACAGAATACATTTCAAGCTGCACCATTGCTAATCACTAAACATACGATCGAGCATTCAAAGCAAATCCAATCTATT
ATTGTGAACTCAGCTAATGCAAATTCATTTACAGGTAAACAGGGCTATGAAGATGCGTTACTTATGCAAAAACTAGTAGC
GAATCAATTGAATATTGAACAACATCATGTCGCTGTAGCTTCTACAGGAGTTATTGGTGAACGCTTGCCGATGGATAAAG
TAAGAAATGGTATCAGACAACTATCTCATACTCAAGTGGATGCAGAGAGTTTTGAAAAAGCAATACTAACTACGGATACA
AGTACGAAACATGTCGCTGTGCAAGTAGAAATCGATGGCAAGCTAGTTACTATTGGTGGAGCGGCAAAAGGTTCAGGAAT
GATCCATCCAAACATGGCTACGATGCTCTCTTTCATTACGACGGATGCAAATGTTAATCAAGATAGCTTGCAGCAGGCGC
TACGTAAGGTTACGGATCAATCCTATAATCAGATTACAGTTGATGGAGATTCCAGTACAAACGATATGGTGTTAGTACTT
GCTAATGGGAGAGCAGAAAATAACGAGTTAAATGAAAGTCATCCGGAATGGTCCGTATTTATGGATGCTTGGAACATCGT
TGCAATCGAATTAGCGAAAATGATTGCTCGAGATGGGGAAGGAGCAACAAAACTGATTGAAGTAATTGTAAAAGGCGCAT
CAACAAATCAACAAGCAAGTCAAATTGCCAAAGCAGTCATTTCTTCCAATCTAGTAAAAACAGCTATTTATGGAAATGAT
GCTAACTGGGGAAGAATTATCGGTGCGATTGGGTATAGTGGTGTACCAGTAGAAGCTAGCAAACTATCGATTGCTATTGG
CGGAATTCAAGTTGTAAATAATGGTGAACCGATTGATTTTGATGAGAAAGATTGCAAACAAGCCTTAAATCAAGAAACCG
TTAATATAGTAATCGATTTACAAAGTGGTATGGACACAGCAACAGCTTGGGGGTGTGATTTAACGTATGATTACATTAGA
ATCAACGCATCTTATCGAACGTGA

Upstream 100 bases:

>100_bases
TGCTGCAGGGCAAGCAATCCAAAACATTAATGTAATGAATGGATGGGATGAAAAAACAGGATTATCTTTCTTGCCAGTAT
ATCCATAAGGGGGAGTATCA

Downstream 100 bases:

>100_bases
GGTGAAGAAATGACTACAGTCGTGTTTAAAGTTGGAGGGAGTGTATTAAATCAACTTTCTCCTAAGTTTTATCAAGTTCT
GTTACAGCTAAAAGAAACAG

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
METTTVKEISILKNGHVTSPSGFYAGGVHCGLRRKKLDLGWIYSDTPASAAGVYTQNTFQAAPLLITKHTIEHSKQIQSI
IVNSANANSFTGKQGYEDALLMQKLVANQLNIEQHHVAVASTGVIGERLPMDKVRNGIRQLSHTQVDAESFEKAILTTDT
STKHVAVQVEIDGKLVTIGGAAKGSGMIHPNMATMLSFITTDANVNQDSLQQALRKVTDQSYNQITVDGDSSTNDMVLVL
ANGRAENNELNESHPEWSVFMDAWNIVAIELAKMIARDGEGATKLIEVIVKGASTNQQASQIAKAVISSNLVKTAIYGND
ANWGRIIGAIGYSGVPVEASKLSIAIGGIQVVNNGEPIDFDEKDCKQALNQETVNIVIDLQSGMDTATAWGCDLTYDYIR
INASYRT

Sequences:

>Translated_407_residues
METTTVKEISILKNGHVTSPSGFYAGGVHCGLRRKKLDLGWIYSDTPASAAGVYTQNTFQAAPLLITKHTIEHSKQIQSI
IVNSANANSFTGKQGYEDALLMQKLVANQLNIEQHHVAVASTGVIGERLPMDKVRNGIRQLSHTQVDAESFEKAILTTDT
STKHVAVQVEIDGKLVTIGGAAKGSGMIHPNMATMLSFITTDANVNQDSLQQALRKVTDQSYNQITVDGDSSTNDMVLVL
ANGRAENNELNESHPEWSVFMDAWNIVAIELAKMIARDGEGATKLIEVIVKGASTNQQASQIAKAVISSNLVKTAIYGND
ANWGRIIGAIGYSGVPVEASKLSIAIGGIQVVNNGEPIDFDEKDCKQALNQETVNIVIDLQSGMDTATAWGCDLTYDYIR
INASYRT
>Mature_407_residues
METTTVKEISILKNGHVTSPSGFYAGGVHCGLRRKKLDLGWIYSDTPASAAGVYTQNTFQAAPLLITKHTIEHSKQIQSI
IVNSANANSFTGKQGYEDALLMQKLVANQLNIEQHHVAVASTGVIGERLPMDKVRNGIRQLSHTQVDAESFEKAILTTDT
STKHVAVQVEIDGKLVTIGGAAKGSGMIHPNMATMLSFITTDANVNQDSLQQALRKVTDQSYNQITVDGDSSTNDMVLVL
ANGRAENNELNESHPEWSVFMDAWNIVAIELAKMIARDGEGATKLIEVIVKGASTNQQASQIAKAVISSNLVKTAIYGND
ANWGRIIGAIGYSGVPVEASKLSIAIGGIQVVNNGEPIDFDEKDCKQALNQETVNIVIDLQSGMDTATAWGCDLTYDYIR
INASYRT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=414, Percent_Identity=38.8888888888889, Blast_Score=268, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_OCEIH (Q8CUN1)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_691997.1
- ProteinModelPortal:   Q8CUN1
- SMR:   Q8CUN1
- MEROPS:   T05.001
- GeneID:   1016973
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1076
- NMPDR:   fig|221109.1.peg.1077
- HOGENOM:   HBG284202
- OMA:   QNRFCAA
- ProtClustDB:   PRK05388
- BioCyc:   OIHE221109:OB1076-MONOMER
- BRENDA:   2.3.1.1
- BRENDA:   2.3.1.35
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 43893; Mature: 43893

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METTTVKEISILKNGHVTSPSGFYAGGVHCGLRRKKLDLGWIYSDTPASAAGVYTQNTFQ
CCCCCEEHEEEEECCCCCCCCCCEECCEEECCEEEEEEEEEEECCCCCCCCCCEECCCCC
AAPLLITKHTIEHSKQIQSIIVNSANANSFTGKQGYEDALLMQKLVANQLNIEQHHVAVA
CCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHEEEEE
STGVIGERLPMDKVRNGIRQLSHTQVDAESFEKAILTTDTSTKHVAVQVEIDGKLVTIGG
ECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCEEEECCCCCEEEEEEEEECCEEEEECC
AAKGSGMIHPNMATMLSFITTDANVNQDSLQQALRKVTDQSYNQITVDGDSSTNDMVLVL
CCCCCCEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEE
ANGRAENNELNESHPEWSVFMDAWNIVAIELAKMIARDGEGATKLIEVIVKGASTNQQAS
ECCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHH
QIAKAVISSNLVKTAIYGNDANWGRIIGAIGYSGVPVEASKLSIAIGGIQVVNNGEPIDF
HHHHHHHHCCCEEEEEECCCCCHHHEEEECCCCCCCCCCCEEEEEEEEEEEECCCCCCCC
DEKDCKQALNQETVNIVIDLQSGMDTATAWGCDLTYDYIRINASYRT
CHHHHHHHHCCCEEEEEEEECCCCCCHHCCCCCEEEEEEEEEEECCC
>Mature Secondary Structure
METTTVKEISILKNGHVTSPSGFYAGGVHCGLRRKKLDLGWIYSDTPASAAGVYTQNTFQ
CCCCCEEHEEEEECCCCCCCCCCEECCEEECCEEEEEEEEEEECCCCCCCCCCEECCCCC
AAPLLITKHTIEHSKQIQSIIVNSANANSFTGKQGYEDALLMQKLVANQLNIEQHHVAVA
CCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHEEEEE
STGVIGERLPMDKVRNGIRQLSHTQVDAESFEKAILTTDTSTKHVAVQVEIDGKLVTIGG
ECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCEEEECCCCCEEEEEEEEECCEEEEECC
AAKGSGMIHPNMATMLSFITTDANVNQDSLQQALRKVTDQSYNQITVDGDSSTNDMVLVL
CCCCCCEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEE
ANGRAENNELNESHPEWSVFMDAWNIVAIELAKMIARDGEGATKLIEVIVKGASTNQQAS
ECCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHH
QIAKAVISSNLVKTAIYGNDANWGRIIGAIGYSGVPVEASKLSIAIGGIQVVNNGEPIDF
HHHHHHHHCCCEEEEEECCCCCHHHEEEECCCCCCCCCCCEEEEEEEEEEEECCCCCCCC
DEKDCKQALNQETVNIVIDLQSGMDTATAWGCDLTYDYIRINASYRT
CHHHHHHHHCCCEEEEEEEECCCCCCHHCCCCCEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376