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The map label for this gene is argC

Identifier: 23098530

GI number: 23098530

Start: 1118173

End: 1119213

Strand: Direct

Name: argC

Synonym: OB1075

Alternate gene names: 23098530

Gene position: 1118173-1119213 (Clockwise)

Preceding gene: 23098529

Following gene: 23098531

Centisome position: 30.8

GC content: 35.06

Gene sequence:

>1041_bases
TTGAAAAAGGCAGCGATTATTGGTGGTACTGGTTATGGTGCTATTGAACTTATTAGACTGTTAGATTCACATCCTTATAT
AGAATTAGCAAAGATCATCTCGCAATCACAACACGGAGAGTTACTTGATGAAACCTATCCACATCTTGCAACCTATGTTA
CACAACCTATGCAAGAGCTACATATTCAACAACTGATCGAAGAGATAGATATTGTTTTTCTAGCAACACCGGCTGGAGTA
GCAAAAGAGATCGCTGCTAGTTTTCTAGATTCTTCTATCCAATGTATTGACTTATCAGGTGATTTACGTTTGTCTTCCAG
TGACTATGAAATGTGGTATCAAAAGAAGCCAGCAAGTGAAGCTTTACTAGAAAAAACGGCATATGGATTAACGGAAGTTT
TTCAAGAGAAGATTAAACAAGCGAATATTATATCTAATCCAGGTTGTTTTCCTACTGCTGCTTTATTAGGTCTTATTCCA
ATGCTTGAAAATAATATTATTGAATCAAAAGGAATTATGATTGATGGCAAAACTGGAATATCTGGAGCAGGTAAAAATTC
CAGTGCAAAAACACATTTTTCAACTACAAATGAAAATGTCACTCCATATAAAATTGGAACACATCAACATATACCAGAGA
TCGAGAAATATTTATCTCAGCATGTTGAAGAATCTTCTGTAAGGGTGACTTTAACGACCCATTTAATTCCAATGACCAGA
GGATTAATGTGTACGATGTATGCACCATTACAACAAGATATAGATACCGCTGATGTTATAGATCTGTATAAACATTATTA
TGAGCAATCATCATTTATCCGGATTCGAAAACAAGGGGAATACCCATCTACGAAAGACGTTACGGGAAGTAACTATTGTG
ATATTGGAGCATATGTCGACAAACGAACAAATCAACTAATTATATCTTCTGCAATTGATAATCTAGTAAAAGGTGCTGCA
GGGCAAGCAATCCAAAACATTAATGTAATGAATGGATGGGATGAAAAAACAGGATTATCTTTCTTGCCAGTATATCCATA
A

Upstream 100 bases:

>100_bases
ATGCATAAATATTAATGTATTTTTATAATTATACTTGCATAAACATACAATAAAATTTATAATATGGATTAATTCCATTT
TGAAAAAGGAGCGGTTTATC

Downstream 100 bases:

>100_bases
GGGGGAGTATCAATGGAAACGACCACAGTGAAAGAAATATCAATATTAAAAAATGGTCATGTGACGAGTCCATCAGGGTT
CTATGCTGGCGGGGTGCATT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKKAAIIGGTGYGAIELIRLLDSHPYIELAKIISQSQHGELLDETYPHLATYVTQPMQELHIQQLIEEIDIVFLATPAGV
AKEIAASFLDSSIQCIDLSGDLRLSSSDYEMWYQKKPASEALLEKTAYGLTEVFQEKIKQANIISNPGCFPTAALLGLIP
MLENNIIESKGIMIDGKTGISGAGKNSSAKTHFSTTNENVTPYKIGTHQHIPEIEKYLSQHVEESSVRVTLTTHLIPMTR
GLMCTMYAPLQQDIDTADVIDLYKHYYEQSSFIRIRKQGEYPSTKDVTGSNYCDIGAYVDKRTNQLIISSAIDNLVKGAA
GQAIQNINVMNGWDEKTGLSFLPVYP

Sequences:

>Translated_346_residues
MKKAAIIGGTGYGAIELIRLLDSHPYIELAKIISQSQHGELLDETYPHLATYVTQPMQELHIQQLIEEIDIVFLATPAGV
AKEIAASFLDSSIQCIDLSGDLRLSSSDYEMWYQKKPASEALLEKTAYGLTEVFQEKIKQANIISNPGCFPTAALLGLIP
MLENNIIESKGIMIDGKTGISGAGKNSSAKTHFSTTNENVTPYKIGTHQHIPEIEKYLSQHVEESSVRVTLTTHLIPMTR
GLMCTMYAPLQQDIDTADVIDLYKHYYEQSSFIRIRKQGEYPSTKDVTGSNYCDIGAYVDKRTNQLIISSAIDNLVKGAA
GQAIQNINVMNGWDEKTGLSFLPVYP
>Mature_346_residues
MKKAAIIGGTGYGAIELIRLLDSHPYIELAKIISQSQHGELLDETYPHLATYVTQPMQELHIQQLIEEIDIVFLATPAGV
AKEIAASFLDSSIQCIDLSGDLRLSSSDYEMWYQKKPASEALLEKTAYGLTEVFQEKIKQANIISNPGCFPTAALLGLIP
MLENNIIESKGIMIDGKTGISGAGKNSSAKTHFSTTNENVTPYKIGTHQHIPEIEKYLSQHVEESSVRVTLTTHLIPMTR
GLMCTMYAPLQQDIDTADVIDLYKHYYEQSSFIRIRKQGEYPSTKDVTGSNYCDIGAYVDKRTNQLIISSAIDNLVKGAA
GQAIQNINVMNGWDEKTGLSFLPVYP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=345, Percent_Identity=33.0434782608696, Blast_Score=186, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6320913, Length=345, Percent_Identity=27.8260869565217, Blast_Score=117, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_OCEIH (Q8CUN2)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_691996.1
- ProteinModelPortal:   Q8CUN2
- SMR:   Q8CUN2
- GeneID:   1016969
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1075
- NMPDR:   fig|221109.1.peg.1076
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- BioCyc:   OIHE221109:OB1075-MONOMER
- BRENDA:   1.2.1.38
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38252; Mature: 38252

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAAIIGGTGYGAIELIRLLDSHPYIELAKIISQSQHGELLDETYPHLATYVTQPMQEL
CCCCEEECCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
HIQQLIEEIDIVFLATPAGVAKEIAASFLDSSIQCIDLSGDLRLSSSDYEMWYQKKPASE
HHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCEEEECCCCEEECCCCHHHHHCCCCHHH
ALLEKTAYGLTEVFQEKIKQANIISNPGCFPTAALLGLIPMLENNIIESKGIMIDGKTGI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEECCCCEEEECCCCC
SGAGKNSSAKTHFSTTNENVTPYKIGTHQHIPEIEKYLSQHVEESSVRVTLTTHLIPMTR
CCCCCCCCCCEEEECCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHH
GLMCTMYAPLQQDIDTADVIDLYKHYYEQSSFIRIRKQGEYPSTKDVTGSNYCDIGAYVD
HHHHHEECHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEECCHHHH
KRTNQLIISSAIDNLVKGAAGQAIQNINVMNGWDEKTGLSFLPVYP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCC
>Mature Secondary Structure
MKKAAIIGGTGYGAIELIRLLDSHPYIELAKIISQSQHGELLDETYPHLATYVTQPMQEL
CCCCEEECCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
HIQQLIEEIDIVFLATPAGVAKEIAASFLDSSIQCIDLSGDLRLSSSDYEMWYQKKPASE
HHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCEEEECCCCEEECCCCHHHHHCCCCHHH
ALLEKTAYGLTEVFQEKIKQANIISNPGCFPTAALLGLIPMLENNIIESKGIMIDGKTGI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEECCCCEEEECCCCC
SGAGKNSSAKTHFSTTNENVTPYKIGTHQHIPEIEKYLSQHVEESSVRVTLTTHLIPMTR
CCCCCCCCCCEEEECCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHH
GLMCTMYAPLQQDIDTADVIDLYKHYYEQSSFIRIRKQGEYPSTKDVTGSNYCDIGAYVD
HHHHHEECHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEECCHHHH
KRTNQLIISSAIDNLVKGAAGQAIQNINVMNGWDEKTGLSFLPVYP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376