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The map label for this gene is argB

Identifier: 23098532

GI number: 23098532

Start: 1120459

End: 1121256

Strand: Direct

Name: argB

Synonym: OB1077

Alternate gene names: 23098532

Gene position: 1120459-1121256 (Clockwise)

Preceding gene: 23098531

Following gene: 23098533

Centisome position: 30.86

GC content: 37.34

Gene sequence:

>798_bases
ATGACTACAGTCGTGTTTAAAGTTGGAGGGAGTGTATTAAATCAACTTTCTCCTAAGTTTTATCAAGTTCTGTTACAGCT
AAAAGAAACAGGAACATGCAATCCAATTATTGTTCACGGTGGAGGACCTGAAATTAATGAAGCGCTAAGTAAAATGAATA
TAAAAACCGAGTTTGTTGACGGTTTACGAGTAACTTCGGAGGAAGTTCTCAGTATTGCTGAGATGGTTATGAGTGGAACA
ATCAATAAACGCATTGTATCAAGTATACAGTCGATTGGTGGAAATGCACTTGGTTTAAGTGGAGTAGATGGAAAACTACT
ACGAGCAAAGCAAATGCATGATGGAAAGCTTGGTTTGGTTGGTGAAGTGGTTGAAGTTAATACAGAATGGTTATCAATCA
TTATGAATAGTGGGGGCATTCCAGTAATTTCACCAATTGCAATAGGTGATGCGGATAAGCGATATAATGTGAACGGTGAT
ATGGCTGCTGGGGCGGTTGCTGAAGCTTTTCAATCAAAGCTAATACTCGTTAGTAATATTCCGGGAGTCATTGAATCGGT
GAACGGAGAAGAAATAATTCATCATCATTTAACTAAACAACAAGTGGAAAGCAAAATAGATTCAGGCGTTATTTACGGAG
GAATGATTCCTAAAGTTCGTTCTGCTTTAGCAAGTCTAAAAAGCGGTGTTGCAGAGTCCGTTATTTTAAATGGTTTGAAT
CCAATTGAAATAAAGAATTATTTAGAAGGAAAAACAGTTGGAACAGTTTTAACAGAAAGAGAGGTAGAGCATGTCTAG

Upstream 100 bases:

>100_bases
CGATTTACAAAGTGGTATGGACACAGCAACAGCTTGGGGGTGTGATTTAACGTATGATTACATTAGAATCAACGCATCTT
ATCGAACGTGAGGTGAAGAA

Downstream 100 bases:

>100_bases
TACAACAAAAGTTTCATCAGCAGTAATGCAAACATATAATCGTTTTCCAATAACAGCAACGAAAGGAAAAGGCAGCTTCC
TATGGGATGATAATGGGGAG

Product: N-acetylglutamate 5-phosphotransferase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MTTVVFKVGGSVLNQLSPKFYQVLLQLKETGTCNPIIVHGGGPEINEALSKMNIKTEFVDGLRVTSEEVLSIAEMVMSGT
INKRIVSSIQSIGGNALGLSGVDGKLLRAKQMHDGKLGLVGEVVEVNTEWLSIIMNSGGIPVISPIAIGDADKRYNVNGD
MAAGAVAEAFQSKLILVSNIPGVIESVNGEEIIHHHLTKQQVESKIDSGVIYGGMIPKVRSALASLKSGVAESVILNGLN
PIEIKNYLEGKTVGTVLTEREVEHV

Sequences:

>Translated_265_residues
MTTVVFKVGGSVLNQLSPKFYQVLLQLKETGTCNPIIVHGGGPEINEALSKMNIKTEFVDGLRVTSEEVLSIAEMVMSGT
INKRIVSSIQSIGGNALGLSGVDGKLLRAKQMHDGKLGLVGEVVEVNTEWLSIIMNSGGIPVISPIAIGDADKRYNVNGD
MAAGAVAEAFQSKLILVSNIPGVIESVNGEEIIHHHLTKQQVESKIDSGVIYGGMIPKVRSALASLKSGVAESVILNGLN
PIEIKNYLEGKTVGTVLTEREVEHV
>Mature_264_residues
TTVVFKVGGSVLNQLSPKFYQVLLQLKETGTCNPIIVHGGGPEINEALSKMNIKTEFVDGLRVTSEEVLSIAEMVMSGTI
NKRIVSSIQSIGGNALGLSGVDGKLLRAKQMHDGKLGLVGEVVEVNTEWLSIIMNSGGIPVISPIAIGDADKRYNVNGDM
AAGAVAEAFQSKLILVSNIPGVIESVNGEEIIHHHLTKQQVESKIDSGVIYGGMIPKVRSALASLKSGVAESVILNGLNP
IEIKNYLEGKTVGTVLTEREVEHV

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=230, Percent_Identity=30, Blast_Score=92, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320913, Length=218, Percent_Identity=27.9816513761468, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_OCEIH (Q8CUN0)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_691998.1
- ProteinModelPortal:   Q8CUN0
- SMR:   Q8CUN0
- GeneID:   1016976
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1077
- NMPDR:   fig|221109.1.peg.1078
- HOGENOM:   HBG497643
- OMA:   MVLCGST
- BioCyc:   OIHE221109:OB1077-MONOMER
- BRENDA:   2.7.2.8
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 28135; Mature: 28004

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: BINDING 63-63 BINDING 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVVFKVGGSVLNQLSPKFYQVLLQLKETGTCNPIIVHGGGPEINEALSKMNIKTEFVD
CCEEEEECCHHHHHHCCHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHCCCHHHHHC
GLRVTSEEVLSIAEMVMSGTINKRIVSSIQSIGGNALGLSGVDGKLLRAKQMHDGKLGLV
CHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHCCCCCCCEE
GEVVEVNTEWLSIIMNSGGIPVISPIAIGDADKRYNVNGDMAAGAVAEAFQSKLILVSNI
HHHHHCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCEEEEECC
PGVIESVNGEEIIHHHLTKQQVESKIDSGVIYGGMIPKVRSALASLKSGVAESVILNGLN
CHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
PIEIKNYLEGKTVGTVLTEREVEHV
HHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTVVFKVGGSVLNQLSPKFYQVLLQLKETGTCNPIIVHGGGPEINEALSKMNIKTEFVD
CEEEEECCHHHHHHCCHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHCCCHHHHHC
GLRVTSEEVLSIAEMVMSGTINKRIVSSIQSIGGNALGLSGVDGKLLRAKQMHDGKLGLV
CHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHCCCCCCCEE
GEVVEVNTEWLSIIMNSGGIPVISPIAIGDADKRYNVNGDMAAGAVAEAFQSKLILVSNI
HHHHHCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCEEEEECC
PGVIESVNGEEIIHHHLTKQQVESKIDSGVIYGGMIPKVRSALASLKSGVAESVILNGLN
CHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
PIEIKNYLEGKTVGTVLTEREVEHV
HHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376