Click here to switch to the map view.

The map label for this gene is yesM [H]

Identifier: 23098232

GI number: 23098232

Start: 831448

End: 833181

Strand: Direct

Name: yesM [H]

Synonym: OB0777

Alternate gene names: 23098232

Gene position: 831448-833181 (Clockwise)

Preceding gene: 23098231

Following gene: 23098233

Centisome position: 22.9

GC content: 34.72

Gene sequence:

>1734_bases
ATGAAAAAGTGGGGATTAAAAAGAAAGTTCATTACATTTTTTCTTGCATTAATGATACCGATATTGTTTGTTAGTTTATT
AATTTATTATCAAACAAATGTAGCGTTGAAAAATCAAGCAATTGAGGAAGCAACCGAAAGATTAAGCAGAAATGAACAAA
ATTTATTGACCGTATTTTCAACAGTAGAAGCGATGTCCTCGTATATGATTTACGATCGTAATTTCCGGAAAATTTTTATC
TCCCAAAAAGATGAAATGTATCAACCTGATTACCAAGAGGCGATGGAAGTTATTAAGGGCTATTTTACATTTCAACTTAT
ATCTAATCCATATATTAATTCTATTTTATTAGAGGGAAGAGATGGGCATTTGGTGAAGCATGGAGAACCAGTTACTGGGA
ATGAGCAAGAATTGGATAAAGTCGCCAAGGAAGCGAAAGGGAGTCCAGTATGGAGTAATCCTTATCAAGTTAAAAGTGAT
TGGAATGAAGATAAATATGTAATCAGCTTAACTAGAATAATTAATGATATGAATAATATCAGTGAACAAATTGGGATCGT
GCGTATCCGGCTTGATCAAGCGGAATTATATAACCAAATAGAGGTACGGTCTCAACAGAGTGACTATTTTATTGTCTCTG
ATAAAGGAGAGGTCATCTTACATCCGGATGTAGATCTGGTTGGCAAGCAATTTCCAGACTCCGGCTTAATTAAATGGATT
GTGGATGGAGTGGAGAAATCATATAGCTATCAGGACGGAGAAAGCCACTTAGTAGTTGTAAAAAATCAGCTTACGAATAC
CAATTGGTTTTCTGTTACTGCTATCGATGAAGATAAGCTAGCTGAGGATTTAACAGAAGTGCGGGCATTGATCGGGTTTC
TAATTGGCATTCTTTTTCTTGCAGGCTTGCTTTTCTTTACCTTCTTTTATCATTCTAATATTAAACGGATACTAGAATTG
ACTAAACAGACAAAGCAAGTGGAAACTGGGAACTTAACTGCAAGTGTCCATGTAGACTCCAATGATGAGATTGGGAAACT
AGGTTACCGTTTTAATAAAATGGTTAAAACTATTCAAAAACATATTGATACAGAATATCGATTAAAAATAAAGCAGAAAG
AGTCGGAACTTAAAGTCTTACAGAATCAAATAAATCCACATTTTCTGTATAACACACTGGATATGATCCGTTGGAATGCA
AGACTGGAAAACGCACCAGAAACTAGTCAATTGATAGAACGGCTTTCTAAAATATTTCGCATGAATCTAAATAATGGAAA
ATCCTTGGTAAAGTTCGAGGAAGAAGTGGAATATAGTCAGGCTTATCTGGAATTGCAGAAGAAGCGATTAGGTGAAAAAC
TTGATTATCAACTTGTGATGGAGGAGCAACTTAAAGGCTATTATGTTATGAAACAAATGATTCAACCTTTAATCGAGAAT
AGTATTCAACATGGTTTTAAGAACCTTCCGAGACAGGGGATAATTCGCATTCATTGTTATCGTGATGAAAATCAAGCAGT
AATTGATGTTATCGATAATGGTTGGGGATTTAATGAACACAAGAAGAACGGTGAGCTACGTGCTGGATATGCGTTGAAAA
ATTTGAACGATCGGATTTCTATTGTTTTTGGAAAACTTTATGGACTAACTATTTTGGATTCAGATGAAGGTGCATTTCTT
CGCATGATCTTACCACTATTAAATGAGGATAAATCAAAAGAATTAGGTGATTAG

Upstream 100 bases:

>100_bases
GTCATCTTCTATTTATTCTTGGAGAAAGAGATTGTGAATGGAATGACTTCTGGAGCCGTAAAGGGTTAATGAGGAATTAA
CTGTTAAAGGACTAGATTGG

Downstream 100 bases:

>100_bases
ATGTCGTCTTACAGAATATTGATTGTCGATGATGAACCGATAATTCGATTAGGTCTTCAACAAACTATACCTTGGGAGAA
ATATCAGATAGAAAAGGTCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MKKWGLKRKFITFFLALMIPILFVSLLIYYQTNVALKNQAIEEATERLSRNEQNLLTVFSTVEAMSSYMIYDRNFRKIFI
SQKDEMYQPDYQEAMEVIKGYFTFQLISNPYINSILLEGRDGHLVKHGEPVTGNEQELDKVAKEAKGSPVWSNPYQVKSD
WNEDKYVISLTRIINDMNNISEQIGIVRIRLDQAELYNQIEVRSQQSDYFIVSDKGEVILHPDVDLVGKQFPDSGLIKWI
VDGVEKSYSYQDGESHLVVVKNQLTNTNWFSVTAIDEDKLAEDLTEVRALIGFLIGILFLAGLLFFTFFYHSNIKRILEL
TKQTKQVETGNLTASVHVDSNDEIGKLGYRFNKMVKTIQKHIDTEYRLKIKQKESELKVLQNQINPHFLYNTLDMIRWNA
RLENAPETSQLIERLSKIFRMNLNNGKSLVKFEEEVEYSQAYLELQKKRLGEKLDYQLVMEEQLKGYYVMKQMIQPLIEN
SIQHGFKNLPRQGIIRIHCYRDENQAVIDVIDNGWGFNEHKKNGELRAGYALKNLNDRISIVFGKLYGLTILDSDEGAFL
RMILPLLNEDKSKELGD

Sequences:

>Translated_577_residues
MKKWGLKRKFITFFLALMIPILFVSLLIYYQTNVALKNQAIEEATERLSRNEQNLLTVFSTVEAMSSYMIYDRNFRKIFI
SQKDEMYQPDYQEAMEVIKGYFTFQLISNPYINSILLEGRDGHLVKHGEPVTGNEQELDKVAKEAKGSPVWSNPYQVKSD
WNEDKYVISLTRIINDMNNISEQIGIVRIRLDQAELYNQIEVRSQQSDYFIVSDKGEVILHPDVDLVGKQFPDSGLIKWI
VDGVEKSYSYQDGESHLVVVKNQLTNTNWFSVTAIDEDKLAEDLTEVRALIGFLIGILFLAGLLFFTFFYHSNIKRILEL
TKQTKQVETGNLTASVHVDSNDEIGKLGYRFNKMVKTIQKHIDTEYRLKIKQKESELKVLQNQINPHFLYNTLDMIRWNA
RLENAPETSQLIERLSKIFRMNLNNGKSLVKFEEEVEYSQAYLELQKKRLGEKLDYQLVMEEQLKGYYVMKQMIQPLIEN
SIQHGFKNLPRQGIIRIHCYRDENQAVIDVIDNGWGFNEHKKNGELRAGYALKNLNDRISIVFGKLYGLTILDSDEGAFL
RMILPLLNEDKSKELGD
>Mature_577_residues
MKKWGLKRKFITFFLALMIPILFVSLLIYYQTNVALKNQAIEEATERLSRNEQNLLTVFSTVEAMSSYMIYDRNFRKIFI
SQKDEMYQPDYQEAMEVIKGYFTFQLISNPYINSILLEGRDGHLVKHGEPVTGNEQELDKVAKEAKGSPVWSNPYQVKSD
WNEDKYVISLTRIINDMNNISEQIGIVRIRLDQAELYNQIEVRSQQSDYFIVSDKGEVILHPDVDLVGKQFPDSGLIKWI
VDGVEKSYSYQDGESHLVVVKNQLTNTNWFSVTAIDEDKLAEDLTEVRALIGFLIGILFLAGLLFFTFFYHSNIKRILEL
TKQTKQVETGNLTASVHVDSNDEIGKLGYRFNKMVKTIQKHIDTEYRLKIKQKESELKVLQNQINPHFLYNTLDMIRWNA
RLENAPETSQLIERLSKIFRMNLNNGKSLVKFEEEVEYSQAYLELQKKRLGEKLDYQLVMEEQLKGYYVMKQMIQPLIEN
SIQHGFKNLPRQGIIRIHCYRDENQAVIDVIDNGWGFNEHKKNGELRAGYALKNLNDRISIVFGKLYGLTILDSDEGAFL
RMILPLLNEDKSKELGD

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=206, Percent_Identity=29.126213592233, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788723, Length=227, Percent_Identity=27.3127753303965, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67104; Mature: 67104

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKWGLKRKFITFFLALMIPILFVSLLIYYQTNVALKNQAIEEATERLSRNEQNLLTVFS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
TVEAMSSYMIYDRNFRKIFISQKDEMYQPDYQEAMEVIKGYFTFQLISNPYINSILLEGR
HHHHHHHHHEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHEEECCCCCCCCEEEECC
DGHLVKHGEPVTGNEQELDKVAKEAKGSPVWSNPYQVKSDWNEDKYVISLTRIINDMNNI
CCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEHHHHHHHHHHH
SEQIGIVRIRLDQAELYNQIEVRSQQSDYFIVSDKGEVILHPDVDLVGKQFPDSGLIKWI
HHHCCEEEEEECHHHHHHHHHHCCCCCCEEEEECCCCEEECCCHHHHCCCCCCCCHHHHH
VDGVEKSYSYQDGESHLVVVKNQLTNTNWFSVTAIDEDKLAEDLTEVRALIGFLIGILFL
HHHHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
AGLLFFTFFYHSNIKRILELTKQTKQVETGNLTASVHVDSNDEIGKLGYRFNKMVKTIQK
HHHHHHHHHHHHHHHHHHHHHHHHHCEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
HIDTEYRLKIKQKESELKVLQNQINPHFLYNTLDMIRWNARLENAPETSQLIERLSKIFR
HCCCEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
MNLNNGKSLVKFEEEVEYSQAYLELQKKRLGEKLDYQLVMEEQLKGYYVMKQMIQPLIEN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SIQHGFKNLPRQGIIRIHCYRDENQAVIDVIDNGWGFNEHKKNGELRAGYALKNLNDRIS
HHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCEEECCHHHCCCCHHE
IVFGKLYGLTILDSDEGAFLRMILPLLNEDKSKELGD
EEEEHHHEEEEEECCCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKKWGLKRKFITFFLALMIPILFVSLLIYYQTNVALKNQAIEEATERLSRNEQNLLTVFS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
TVEAMSSYMIYDRNFRKIFISQKDEMYQPDYQEAMEVIKGYFTFQLISNPYINSILLEGR
HHHHHHHHHEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHEEECCCCCCCCEEEECC
DGHLVKHGEPVTGNEQELDKVAKEAKGSPVWSNPYQVKSDWNEDKYVISLTRIINDMNNI
CCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEHHHHHHHHHHH
SEQIGIVRIRLDQAELYNQIEVRSQQSDYFIVSDKGEVILHPDVDLVGKQFPDSGLIKWI
HHHCCEEEEEECHHHHHHHHHHCCCCCCEEEEECCCCEEECCCHHHHCCCCCCCCHHHHH
VDGVEKSYSYQDGESHLVVVKNQLTNTNWFSVTAIDEDKLAEDLTEVRALIGFLIGILFL
HHHHHHCCCCCCCCCCEEEEEECCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
AGLLFFTFFYHSNIKRILELTKQTKQVETGNLTASVHVDSNDEIGKLGYRFNKMVKTIQK
HHHHHHHHHHHHHHHHHHHHHHHHHCEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
HIDTEYRLKIKQKESELKVLQNQINPHFLYNTLDMIRWNARLENAPETSQLIERLSKIFR
HCCCEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
MNLNNGKSLVKFEEEVEYSQAYLELQKKRLGEKLDYQLVMEEQLKGYYVMKQMIQPLIEN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SIQHGFKNLPRQGIIRIHCYRDENQAVIDVIDNGWGFNEHKKNGELRAGYALKNLNDRIS
HHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCEEECCHHHCCCCHHE
IVFGKLYGLTILDSDEGAFLRMILPLLNEDKSKELGD
EEEEHHHEEEEEECCCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]