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The map label for this gene is hslO

Identifier: 23097537

GI number: 23097537

Start: 84524

End: 85393

Strand: Direct

Name: hslO

Synonym: OB0082

Alternate gene names: 23097537

Gene position: 84524-85393 (Clockwise)

Preceding gene: 23097536

Following gene: 23097538

Centisome position: 2.33

GC content: 38.28

Gene sequence:

>870_bases
ATGAAGGATTACTTAATTAAAGCGACAGCAAATAATGGGAAAATTAGAGCGTATGCCGTTCAATCCACAAACACTATAGA
AGAAGCGAGAAGAAGACAGGATACGTTTGCAACTGCATCTGCTGCACTTGGCAGAACGATAACAATCACGGCAATGATGG
GAGCTATGCTAAAAGGTGATGACTCTATTACAACGAAAGTAATGGGTAATGGTCCACTTGGAGCTATTGTTGCTGATGCT
GATGCTGATGGACATGTTCGTGGATATGTTACGAATCCACATGTTGATTTCGATTTAAATGATAAAGGTAAATTAGATGT
TGCGCGAGCAGTAGGTACAGAAGGAAATATTAGTGTTATTAAAGATTTAGGATTAAAGGATTTTTTCACAGGGGAAACAC
CGATTGTTTCTGGGGAGATTAGTGAAGACTTCACCTATTACTATGCTACTTCAGAACAATTGCCATCAGCTGTTGGTGCA
GGGGTTTTGGTAAATCCAGATCATACTATTTTAGCTGCAGGAGGTTTTATCGTTCAAGTAATGCCTGGTGCAGAAGAAGA
AGTAATTAATGAATTAGAAGATCAAATTCAAGCCATTCCTGCAATATCTTCGTTAATTCGTGAAGGAAAATCTCCGGAAG
AAATTCTAACCCAACTATTTGGCGAAGAGTGTTTAACCATACATGAAAAAATGCCAATTGAGTTTCGTTGTAAGTGCTCC
AAAGATCGTCTTGCCCAAGCAATTATCGGATTAGGAAATGATGAAATACAGGCGATGATTGAAGAAGACCAAGGTGCAGA
GGCAACTTGTCATTTTTGTAATGAAAAGTATCATTTTACTGAGGAAGAATTAGAAGACCTTAAACAGTAG

Upstream 100 bases:

>100_bases
TCTGCAAGCATTGATATCGTAGAGCCTTATTTGACGTTAAAAGGATTGCATTTGATTTACCAAAAAAATAATTAGTAAAA
TAAAAGGAGAGATATTCCCA

Downstream 100 bases:

>100_bases
AGAGAAGAAAGGAAGTTACACTTCATGTCAAAAAAATTGTTGCTCGGAATCGTTGTGGTACTGCTGATTACGAATATTGC
AACTCTATTGTTTGTGGGAG

Product: chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MKDYLIKATANNGKIRAYAVQSTNTIEEARRRQDTFATASAALGRTITITAMMGAMLKGDDSITTKVMGNGPLGAIVADA
DADGHVRGYVTNPHVDFDLNDKGKLDVARAVGTEGNISVIKDLGLKDFFTGETPIVSGEISEDFTYYYATSEQLPSAVGA
GVLVNPDHTILAAGGFIVQVMPGAEEEVINELEDQIQAIPAISSLIREGKSPEEILTQLFGEECLTIHEKMPIEFRCKCS
KDRLAQAIIGLGNDEIQAMIEEDQGAEATCHFCNEKYHFTEEELEDLKQ

Sequences:

>Translated_289_residues
MKDYLIKATANNGKIRAYAVQSTNTIEEARRRQDTFATASAALGRTITITAMMGAMLKGDDSITTKVMGNGPLGAIVADA
DADGHVRGYVTNPHVDFDLNDKGKLDVARAVGTEGNISVIKDLGLKDFFTGETPIVSGEISEDFTYYYATSEQLPSAVGA
GVLVNPDHTILAAGGFIVQVMPGAEEEVINELEDQIQAIPAISSLIREGKSPEEILTQLFGEECLTIHEKMPIEFRCKCS
KDRLAQAIIGLGNDEIQAMIEEDQGAEATCHFCNEKYHFTEEELEDLKQ
>Mature_289_residues
MKDYLIKATANNGKIRAYAVQSTNTIEEARRRQDTFATASAALGRTITITAMMGAMLKGDDSITTKVMGNGPLGAIVADA
DADGHVRGYVTNPHVDFDLNDKGKLDVARAVGTEGNISVIKDLGLKDFFTGETPIVSGEISEDFTYYYATSEQLPSAVGA
GVLVNPDHTILAAGGFIVQVMPGAEEEVINELEDQIQAIPAISSLIREGKSPEEILTQLFGEECLTIHEKMPIEFRCKCS
KDRLAQAIIGLGNDEIQAMIEEDQGAEATCHFCNEKYHFTEEELEDLKQ

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=293, Percent_Identity=23.2081911262799, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_OCEIH (Q8CXP5)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_691003.1
- ProteinModelPortal:   Q8CXP5
- SMR:   Q8CXP5
- GeneID:   1015148
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB0082
- NMPDR:   fig|221109.1.peg.82
- HOGENOM:   HBG286231
- OMA:   AYYFTVS
- BioCyc:   OIHE221109:OB0082-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 31366; Mature: 31366

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDYLIKATANNGKIRAYAVQSTNTIEEARRRQDTFATASAALGRTITITAMMGAMLKGD
CCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCC
DSITTKVMGNGPLGAIVADADADGHVRGYVTNPHVDFDLNDKGKLDVARAVGTEGNISVI
CCEEEEEECCCCCEEEEEECCCCCCEEEEEECCEEEEECCCCCCEEHHHHCCCCCCCHHH
KDLGLKDFFTGETPIVSGEISEDFTYYYATSEQLPSAVGAGVLVNPDHTILAAGGFIVQV
HHCCCCHHCCCCCCEEECCCCCCEEEEEECCHHCCHHHCCCEEECCCCEEEEECCEEEEE
MPGAEEEVINELEDQIQAIPAISSLIREGKSPEEILTQLFGEECLTIHEKMPIEFRCKCS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHCCCEEEEEECC
KDRLAQAIIGLGNDEIQAMIEEDQGAEATCHFCNEKYHFTEEELEDLKQ
HHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MKDYLIKATANNGKIRAYAVQSTNTIEEARRRQDTFATASAALGRTITITAMMGAMLKGD
CCCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCC
DSITTKVMGNGPLGAIVADADADGHVRGYVTNPHVDFDLNDKGKLDVARAVGTEGNISVI
CCEEEEEECCCCCEEEEEECCCCCCEEEEEECCEEEEECCCCCCEEHHHHCCCCCCCHHH
KDLGLKDFFTGETPIVSGEISEDFTYYYATSEQLPSAVGAGVLVNPDHTILAAGGFIVQV
HHCCCCHHCCCCCCEEECCCCCCEEEEEECCHHCCHHHCCCEEECCCCEEEEECCEEEEE
MPGAEEEVINELEDQIQAIPAISSLIREGKSPEEILTQLFGEECLTIHEKMPIEFRCKCS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHCCCEEEEEECC
KDRLAQAIIGLGNDEIQAMIEEDQGAEATCHFCNEKYHFTEEELEDLKQ
HHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376