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The map label for this gene is coaX

Identifier: 23097536

GI number: 23097536

Start: 83731

End: 84498

Strand: Direct

Name: coaX

Synonym: OB0081

Alternate gene names: 23097536

Gene position: 83731-84498 (Clockwise)

Preceding gene: 23097535

Following gene: 23097537

Centisome position: 2.31

GC content: 34.11

Gene sequence:

>768_bases
ATGCTATTTGTACTTGATGTAGGAAATACTAACACAGTTTTAGGTGTCTTTGACCAAGGTGAATTAACTCATCATTGGCG
AATTAAAACCGATCGTTATAAAACAGAAGATGAATTTGGCATGCTTATTCATTCTCTTTTTCAACATAAAAAATTATCAT
TTGAAGATATTAAAGGTGTGATTATATCTTCGGTTGTTCCACCTATATTATTTGCTTTAGAGAAAATGAGTAGAGATTAT
TTTCATTTAGATGCCGTAGTAATTGGAAAAACTTCTTATCAAACTTTTTTAAACATGAATTACCCTAATCCTCAAGAAAT
TGGTGCAGATAGAATTGTTAATGCTGTGGCAGCTACGGAAGAATACGGCTCACCACTAATTATCATTGATTTTGGAACAG
CAACTACGTATTGCTATATCGACGAGGATACTGCATATGCTGGAGGGATCATTACACCGGGGATTAATATATCAATGGAA
GCACTATATAGTAATGCATCAAAATTACCAAAAATTGAAATTCAAAAACCGGAAACAGTGATTGGTTCTACAACAGTAGA
CGCCATGACTTCTGGGGTGTTCTATGGATATATTGGACAAGTAGATGGTTTGGTAAAGAGAATCAAAGATGAAAAAGGGA
CAAATCCAACTGTGATTGCAACAGGCGGACTTGCAAAATTAATTGCGCATGAATCTGCAAGCATTGATATCGTAGAGCCT
TATTTGACGTTAAAAGGATTGCATTTGATTTACCAAAAAAATAATTAG

Upstream 100 bases:

>100_bases
TTCTTAAGAACATTTGTCAATGCAAGCTTTGAGCTTTTCTTATATTTCCTAAAGTATGTTATATTATAGAACAGATAAGA
TAAGGAAGGTAGGCTGACTG

Downstream 100 bases:

>100_bases
TAAAATAAAAGGAGAGATATTCCCAATGAAGGATTACTTAATTAAAGCGACAGCAAATAATGGGAAAATTAGAGCGTATG
CCGTTCAATCCACAAACACT

Product: hypothetical protein

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MLFVLDVGNTNTVLGVFDQGELTHHWRIKTDRYKTEDEFGMLIHSLFQHKKLSFEDIKGVIISSVVPPILFALEKMSRDY
FHLDAVVIGKTSYQTFLNMNYPNPQEIGADRIVNAVAATEEYGSPLIIIDFGTATTYCYIDEDTAYAGGIITPGINISME
ALYSNASKLPKIEIQKPETVIGSTTVDAMTSGVFYGYIGQVDGLVKRIKDEKGTNPTVIATGGLAKLIAHESASIDIVEP
YLTLKGLHLIYQKNN

Sequences:

>Translated_255_residues
MLFVLDVGNTNTVLGVFDQGELTHHWRIKTDRYKTEDEFGMLIHSLFQHKKLSFEDIKGVIISSVVPPILFALEKMSRDY
FHLDAVVIGKTSYQTFLNMNYPNPQEIGADRIVNAVAATEEYGSPLIIIDFGTATTYCYIDEDTAYAGGIITPGINISME
ALYSNASKLPKIEIQKPETVIGSTTVDAMTSGVFYGYIGQVDGLVKRIKDEKGTNPTVIATGGLAKLIAHESASIDIVEP
YLTLKGLHLIYQKNN
>Mature_255_residues
MLFVLDVGNTNTVLGVFDQGELTHHWRIKTDRYKTEDEFGMLIHSLFQHKKLSFEDIKGVIISSVVPPILFALEKMSRDY
FHLDAVVIGKTSYQTFLNMNYPNPQEIGADRIVNAVAATEEYGSPLIIIDFGTATTYCYIDEDTAYAGGIITPGINISME
ALYSNASKLPKIEIQKPETVIGSTTVDAMTSGVFYGYIGQVDGLVKRIKDEKGTNPTVIATGGLAKLIAHESASIDIVEP
YLTLKGLHLIYQKNN

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_OCEIH (Q8EU15)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_691002.1
- ProteinModelPortal:   Q8EU15
- SMR:   Q8EU15
- GeneID:   1015146
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB0081
- NMPDR:   fig|221109.1.peg.81
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- BioCyc:   OIHE221109:OB0081-MONOMER
- BRENDA:   2.7.1.33
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28160; Mature: 28160

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: ACT_SITE 110-110 BINDING 101-101 BINDING 133-133 BINDING 185-185

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFVLDVGNTNTVLGVFDQGELTHHWRIKTDRYKTEDEFGMLIHSLFQHKKLSFEDIKGV
CEEEEEECCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
IISSVVPPILFALEKMSRDYFHLDAVVIGKTSYQTFLNMNYPNPQEIGADRIVNAVAATE
HHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCEEEEEECCCCCHHHHCHHHHHHHHHHHH
EYGSPLIIIDFGTATTYCYIDEDTAYAGGIITPGINISMEALYSNASKLPKIEIQKPETV
HHCCCEEEEEECCCEEEEEEECCCCCCCCEECCCCCEEHHHHHCCHHHCCEEEECCCCEE
IGSTTVDAMTSGVFYGYIGQVDGLVKRIKDEKGTNPTVIATGGLAKLIAHESASIDIVEP
ECCCHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHCCCCCEEEECH
YLTLKGLHLIYQKNN
HHHCCEEEEEEEECC
>Mature Secondary Structure
MLFVLDVGNTNTVLGVFDQGELTHHWRIKTDRYKTEDEFGMLIHSLFQHKKLSFEDIKGV
CEEEEEECCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
IISSVVPPILFALEKMSRDYFHLDAVVIGKTSYQTFLNMNYPNPQEIGADRIVNAVAATE
HHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCEEEEEECCCCCHHHHCHHHHHHHHHHHH
EYGSPLIIIDFGTATTYCYIDEDTAYAGGIITPGINISMEALYSNASKLPKIEIQKPETV
HHCCCEEEEEECCCEEEEEEECCCCCCCCEECCCCCEEHHHHHCCHHHCCEEEECCCCEE
IGSTTVDAMTSGVFYGYIGQVDGLVKRIKDEKGTNPTVIATGGLAKLIAHESASIDIVEP
ECCCHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHCCCCCEEEECH
YLTLKGLHLIYQKNN
HHHCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376