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The map label for this gene is mecA1 [H]

Identifier: 229918691

GI number: 229918691

Start: 2942021

End: 2942599

Strand: Direct

Name: mecA1 [H]

Synonym: EAT1b_2978

Alternate gene names: 229918691

Gene position: 2942021-2942599 (Clockwise)

Preceding gene: 229918690

Following gene: 229918692

Centisome position: 98.07

GC content: 45.94

Gene sequence:

>579_bases
TTGAGATTTGAAAAACAAACAAAAGAACATCTTCGTGTATATGTGACTGCGAATGAGCTCTCGTTACGTGGAATCGCCAT
CGATACGATCGTGGGGGAAAACGGTCAGCAGCTGTGGAAAGAACTACTTGAAACAGCAGAAAGTGAGTACGGATTTTCAC
CGCAAGGAGCGGTTGATTTGAATGTGACAATGTTTCCTCGCGATGGACTCGTCATCGATGTTCAAAAAGGTGAAGCGATT
GCTGAGCTCGATGTCGAACAGGTCGAGATTCGATTGACGATTGATGTGATCCATCATTTGATTTATCAGTTCGATGACAT
TGAAGATGTGATCAACGCCTCGATTCGTCTGTTCCCGCATATACATGAAACCGAGCAGGGTGGGACGCTTTATCATTACA
ACGGTCGTTACTATCTTCACTTCGTTGAGGTGCTTCCTTCACAAGTGGAAGAACGACTCGCGGCCATTTTGTCCGAGTAC
GGCAAGACGACTACGGTCAGCCCGTACGTTATGATGGAATACGGAAAGACGATTCAAACTGAACAAGCCGTGAAAGAGCT
GTACGATGCATTCGCATGA

Upstream 100 bases:

>100_bases
CACTCCTGAAGAGTGGACAAAATGGTTATCAACTATTTGACACGGGATGAAAACGGGAGTAGCTTATTATTAGGATTGAC
TATTCACTGGAGGTTTTCGA

Downstream 100 bases:

>100_bases
GTACGGCTTTTTTTACTTTTCTGTTCCTATTGTTTTTAGGATGTCCGTGTTATGATTAGACTTGAATTTTCAGTAGTTAG
TTGAAGGAGAGATTGGAATG

Product: Negative regulator of genetic competence

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MRFEKQTKEHLRVYVTANELSLRGIAIDTIVGENGQQLWKELLETAESEYGFSPQGAVDLNVTMFPRDGLVIDVQKGEAI
AELDVEQVEIRLTIDVIHHLIYQFDDIEDVINASIRLFPHIHETEQGGTLYHYNGRYYLHFVEVLPSQVEERLAAILSEY
GKTTTVSPYVMMEYGKTIQTEQAVKELYDAFA

Sequences:

>Translated_192_residues
MRFEKQTKEHLRVYVTANELSLRGIAIDTIVGENGQQLWKELLETAESEYGFSPQGAVDLNVTMFPRDGLVIDVQKGEAI
AELDVEQVEIRLTIDVIHHLIYQFDDIEDVINASIRLFPHIHETEQGGTLYHYNGRYYLHFVEVLPSQVEERLAAILSEY
GKTTTVSPYVMMEYGKTIQTEQAVKELYDAFA
>Mature_192_residues
MRFEKQTKEHLRVYVTANELSLRGIAIDTIVGENGQQLWKELLETAESEYGFSPQGAVDLNVTMFPRDGLVIDVQKGEAI
AELDVEQVEIRLTIDVIHHLIYQFDDIEDVINASIRLFPHIHETEQGGTLYHYNGRYYLHFVEVLPSQVEERLAAILSEY
GKTTTVSPYVMMEYGKTIQTEQAVKELYDAFA

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When ove

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008681 [H]

Pfam domain/function: PF05389 MecA [H]

EC number: NA

Molecular weight: Translated: 21999; Mature: 21999

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFEKQTKEHLRVYVTANELSLRGIAIDTIVGENGQQLWKELLETAESEYGFSPQGAVDL
CCCCHHHHHHEEEEEEECCEEECEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEE
NVTMFPRDGLVIDVQKGEAIAELDVEQVEIRLTIDVIHHLIYQFDDIEDVINASIRLFPH
EEEEECCCCEEEEECCCCEEECCCHHHEEEEEHHHHHHHHHHHHCCHHHHHCCCEEEECC
IHETEQGGTLYHYNGRYYLHFVEVLPSQVEERLAAILSEYGKTTTVSPYVMMEYGKTIQT
EECCCCCCEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCH
EQAVKELYDAFA
HHHHHHHHHHCC
>Mature Secondary Structure
MRFEKQTKEHLRVYVTANELSLRGIAIDTIVGENGQQLWKELLETAESEYGFSPQGAVDL
CCCCHHHHHHEEEEEEECCEEECEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEE
NVTMFPRDGLVIDVQKGEAIAELDVEQVEIRLTIDVIHHLIYQFDDIEDVINASIRLFPH
EEEEECCCCEEEEECCCCEEECCCHHHEEEEEHHHHHHHHHHHHCCHHHHHCCCEEEECC
IHETEQGGTLYHYNGRYYLHFVEVLPSQVEERLAAILSEYGKTTTVSPYVMMEYGKTIQT
EECCCCCCEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCH
EQAVKELYDAFA
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]