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The map label for this gene is hemY [H]

Identifier: 229918185

GI number: 229918185

Start: 2419860

End: 2421254

Strand: Direct

Name: hemY [H]

Synonym: EAT1b_2465

Alternate gene names: 229918185

Gene position: 2419860-2421254 (Clockwise)

Preceding gene: 229918184

Following gene: 229918186

Centisome position: 80.66

GC content: 52.54

Gene sequence:

>1395_bases
TTGTGCATCATGCGTAAATTCACGATTGTCGGTGGTGGGATCACAGGTCTCACCGCCGCTTTTTATGCAGAGCGTTATTT
GCCGGAAGACGTGACCATCACGTTGCTTGAGGCGACGGATCGCCTCGGAGGAAAGATTGATACGTATGAAACGGGCGAGT
TTGCGGTGGAACGTGGTCCGGACTCGTATGTCTTTCGTAAGACTGCGATGACGGAATTGATTGAAGACGTCGGTTTAGGC
GATGAACTCGTTCGCAATGGAGTCGGTCAAGCTTACGTCCTTCATCATGACGGGCTCCACCCGATTCCGAAGCAGACGGT
GATGGGGATCCCGCTCGACGTCAATGCGTTTCGTGAGACGACGTTGCTCTCGGAGGAAGAGCATGAGGACTTGAAGCAGA
TGTTACTGTCCCCTCCAGATGTAAAAGTGCCAGACTCGGACGTCTCACTCGGCCTCTACCTTCGTGAGCGTGTCGGGGAC
CCAATTGTCGACCGATTGATTGAACCGTTACTCTCTGGTATCTATGCTGGAGACATCGATCAAATGAGTGCGATGTCGAC
ATTCCCGCAGTTCATCGAGGGAGAAAAGAAATACGGCAACTTGTATGAAGGGATGCGACACTTACGACCGGAACAACGAG
TCGCAGAAGTCGGGGCAAAGAAGGTCGGTCAGTTCGCTTCGTTGAAACGTGGACTCAAATCACTGACAGACCGCTTGGCA
GAACGGTTGGAACGTACTGAAATCGTATTAAACTGTTCCGTCGAACAAGTATCCGAACGTGAGGACGGGTACCGTCTATT
CACGAATCGCGGAGATATCGACACGGACCATCTCGTGTTGACGGTCCCACCGCGCCTCATTCGTCAGTTCCTCCCGAAAG
TCGACAGTGACTTTTTGGCGGACATGAAGCCACATGCGACGGCCACATGCTCGCTTGTATTCAAAGAAGAAGATATTGAG
CTTCCGTTCGTCGGGACAGGGTTCGTGACGAGTCAAGAAGCGGATGTGACAATCACGGCATGTACGTTCATCGACCAGAA
ATGGCCGCATGCGGTGCCGGAAGGATATCACGTCCTTCGTGTCTTTTTAGGTCGTCCGGGGGCAGATGATATCGTCGAAG
CATCCGATGAAGAAATCATCGAGACGGCATTACACGATCTCCGTGGCCTGATGCGCATTCATCGTGAACCGGTTCAAACC
GTCGTCAGTCGACTCCGTGATGGACTGCCTCCTTATGCGGTCTTTCATGCGGACCGTGTCAAAGCACTCCGAGCCGAGAT
GAGCCGGGTATATCCAGGCGTCATTCTCGCCGGAATCGCCTATGACGGAATTGGGATGCCGGACTGTGTGAAGAGTATTC
GGGAACAAGTGAAGGCATTGCGTGAAAAAAATTGA

Upstream 100 bases:

>100_bases
GTTGTCTGTGACCGCCTCGGTGTTCACTACGCACGTCCAGCTATGCCAAATGCAGAGCGAAGCTTCATCGAAGCCATCGC
GGATCGAATGGAAAGCGTGA

Downstream 100 bases:

>100_bases
GATTTGATGAAGGGAGGGTTCGGATTGTTCCGCAACCCTCTCTTTTTGTTATAGTTAGAAGCGAAAGAGAAAAAGGAGTG
ATGGAAGATGGCAACGTATA

Product: protoporphyrinogen oxidase

Products: NA

Alternate protein names: PPO [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MCIMRKFTIVGGGITGLTAAFYAERYLPEDVTITLLEATDRLGGKIDTYETGEFAVERGPDSYVFRKTAMTELIEDVGLG
DELVRNGVGQAYVLHHDGLHPIPKQTVMGIPLDVNAFRETTLLSEEEHEDLKQMLLSPPDVKVPDSDVSLGLYLRERVGD
PIVDRLIEPLLSGIYAGDIDQMSAMSTFPQFIEGEKKYGNLYEGMRHLRPEQRVAEVGAKKVGQFASLKRGLKSLTDRLA
ERLERTEIVLNCSVEQVSEREDGYRLFTNRGDIDTDHLVLTVPPRLIRQFLPKVDSDFLADMKPHATATCSLVFKEEDIE
LPFVGTGFVTSQEADVTITACTFIDQKWPHAVPEGYHVLRVFLGRPGADDIVEASDEEIIETALHDLRGLMRIHREPVQT
VVSRLRDGLPPYAVFHADRVKALRAEMSRVYPGVILAGIAYDGIGMPDCVKSIREQVKALREKN

Sequences:

>Translated_464_residues
MCIMRKFTIVGGGITGLTAAFYAERYLPEDVTITLLEATDRLGGKIDTYETGEFAVERGPDSYVFRKTAMTELIEDVGLG
DELVRNGVGQAYVLHHDGLHPIPKQTVMGIPLDVNAFRETTLLSEEEHEDLKQMLLSPPDVKVPDSDVSLGLYLRERVGD
PIVDRLIEPLLSGIYAGDIDQMSAMSTFPQFIEGEKKYGNLYEGMRHLRPEQRVAEVGAKKVGQFASLKRGLKSLTDRLA
ERLERTEIVLNCSVEQVSEREDGYRLFTNRGDIDTDHLVLTVPPRLIRQFLPKVDSDFLADMKPHATATCSLVFKEEDIE
LPFVGTGFVTSQEADVTITACTFIDQKWPHAVPEGYHVLRVFLGRPGADDIVEASDEEIIETALHDLRGLMRIHREPVQT
VVSRLRDGLPPYAVFHADRVKALRAEMSRVYPGVILAGIAYDGIGMPDCVKSIREQVKALREKN
>Mature_464_residues
MCIMRKFTIVGGGITGLTAAFYAERYLPEDVTITLLEATDRLGGKIDTYETGEFAVERGPDSYVFRKTAMTELIEDVGLG
DELVRNGVGQAYVLHHDGLHPIPKQTVMGIPLDVNAFRETTLLSEEEHEDLKQMLLSPPDVKVPDSDVSLGLYLRERVGD
PIVDRLIEPLLSGIYAGDIDQMSAMSTFPQFIEGEKKYGNLYEGMRHLRPEQRVAEVGAKKVGQFASLKRGLKSLTDRLA
ERLERTEIVLNCSVEQVSEREDGYRLFTNRGDIDTDHLVLTVPPRLIRQFLPKVDSDFLADMKPHATATCSLVFKEEDIE
LPFVGTGFVTSQEADVTITACTFIDQKWPHAVPEGYHVLRVFLGRPGADDIVEASDEEIIETALHDLRGLMRIHREPVQT
VVSRLRDGLPPYAVFHADRVKALRAEMSRVYPGVILAGIAYDGIGMPDCVKSIREQVKALREKN

Specific function: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. Also oxidizes the pathway intermediate coproporphyrinogen-III [H]

COG id: COG1232

COG function: function code H; Protoporphyrinogen oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protoporphyrinogen oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR016040
- InterPro:   IPR004572 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: =1.3.3.4 [H]

Molecular weight: Translated: 51852; Mature: 51852

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCIMRKFTIVGGGITGLTAAFYAERYLPEDVTITLLEATDRLGGKIDTYETGEFAVERGP
CCCEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCCCCCCCCEECCC
DSYVFRKTAMTELIEDVGLGDELVRNGVGQAYVLHHDGLHPIPKQTVMGIPLDVNAFRET
CHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEECCCCCCCCCHHEECCCCCHHHHHHH
TLLSEEEHEDLKQMLLSPPDVKVPDSDVSLGLYLRERVGDPIVDRLIEPLLSGIYAGDID
HHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHH
QMSAMSTFPQFIEGEKKYGNLYEGMRHLRPEQRVAEVGAKKVGQFASLKRGLKSLTDRLA
HHHHHHHHHHHHCCCHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERLERTEIVLNCSVEQVSEREDGYRLFTNRGDIDTDHLVLTVPPRLIRQFLPKVDSDFLA
HHHHHHHEEEECCHHHHHCCCCCEEEECCCCCCCCCCEEEECCHHHHHHHHCCCCCHHHH
DMKPHATATCSLVFKEEDIELPFVGTGFVTSQEADVTITACTFIDQKWPHAVPEGYHVLR
CCCCCCCEEEEEEEECCCCCCCEEECCCEECCCCCEEEEEEEHHCCCCCCCCCCHHHHHH
VFLGRPGADDIVEASDEEIIETALHDLRGLMRIHREPVQTVVSRLRDGLPPYAVFHADRV
HHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHH
KALRAEMSRVYPGVILAGIAYDGIGMPDCVKSIREQVKALREKN
HHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MCIMRKFTIVGGGITGLTAAFYAERYLPEDVTITLLEATDRLGGKIDTYETGEFAVERGP
CCCEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCCCCCCCCEECCC
DSYVFRKTAMTELIEDVGLGDELVRNGVGQAYVLHHDGLHPIPKQTVMGIPLDVNAFRET
CHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEECCCCCCCCCHHEECCCCCHHHHHHH
TLLSEEEHEDLKQMLLSPPDVKVPDSDVSLGLYLRERVGDPIVDRLIEPLLSGIYAGDID
HHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHH
QMSAMSTFPQFIEGEKKYGNLYEGMRHLRPEQRVAEVGAKKVGQFASLKRGLKSLTDRLA
HHHHHHHHHHHHCCCHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERLERTEIVLNCSVEQVSEREDGYRLFTNRGDIDTDHLVLTVPPRLIRQFLPKVDSDFLA
HHHHHHHEEEECCHHHHHCCCCCEEEECCCCCCCCCCEEEECCHHHHHHHHCCCCCHHHH
DMKPHATATCSLVFKEEDIELPFVGTGFVTSQEADVTITACTFIDQKWPHAVPEGYHVLR
CCCCCCCEEEEEEEECCCCCCCEEECCCEECCCCCEEEEEEEHHCCCCCCCCCCHHHHHH
VFLGRPGADDIVEASDEEIIETALHDLRGLMRIHREPVQTVVSRLRDGLPPYAVFHADRV
HHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHH
KALRAEMSRVYPGVILAGIAYDGIGMPDCVKSIREQVKALREKN
HHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1459957; 9579061; 9384377; 8288631 [H]