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The map label for this gene is alr2 [H]

Identifier: 229917987

GI number: 229917987

Start: 2219764

End: 2220852

Strand: Direct

Name: alr2 [H]

Synonym: EAT1b_2266

Alternate gene names: 229917987

Gene position: 2219764-2220852 (Clockwise)

Preceding gene: 229917986

Following gene: 229917988

Centisome position: 73.99

GC content: 50.87

Gene sequence:

>1089_bases
ATGGGAGTCACAATTGACTTAAATGCGATTCGCGAAAACAAACGCCGGATTGAAGCGCTCGGGCGCCCCGTGTTTGCGGT
CGTGAAAAACAATGCCTATAACCTAGGAATGGAGCCAGTTGTGACGACTTTGTATGATGAAGGGGTCCGTCACTTCATGG
TGACCACGTTAGAAGAAGCGCTCGAAGTGCGAACGCATGCAGAGTCGGCTCGCGTCCTCATCATGAATCCGGTATACACG
TGGGAACACGTGCATGCCCATGATTTTGACGTCGCAATCGGCTCGTATGAATGGCTCGTCTCGCAGCGGGAGCATCTCGA
TGGCGTTCGCCTTCATTTGAAACTAGACGTCGGCATGAACCGATTCGGTGCCAAAACGTTTGAAGAAGCGTTACGGATCG
TCGCCTTCTGCCAAAATGAAGGATTGAACCTTGTCGGATTATGTACACATTTTCCGCTTGCGGATGCAGATAATGCCGAA
GTTGAGCATAGCGTCCAAGTCGAACGTTTTGCTGACTGGTCGACACGTTTGATGGAACGTCATACGTTTGAATTGATTCA
TGCCGCGAACAGTGCGGCCACGCTCCAAGACGACTCGCGCTTGCACCATTGCACACATGTGCGTGTCGGTATTTTCTTAT
ACGGTTATTCATCGGTCGAGCCGGTTGAGTGGCTCGTACCTGCGTTTTACTGGGAAACCGAAGTGGTTGCCGTCCACGAC
ATCGAAGCGGGGGCTCATGTCGGGTATGGAACGGGATATACCGCAGAATCAAAAGAACGGATTGCTGTCTTACCTGTCGG
ATATGGGGACGGATTGATGCGAGCGAGACGTCATTTACCCGTTCACATCGAGGGGAGAGCTTATCCGTTCGTCAGCAATA
TCTTTATGAGCCATAGCTTCATCAAAGTCGACGAAGACGTACAAATCGGCGACCGCGTCGCATTATATGGGATCGAAACG
AAAATCGATGACGTGACACGTGTTGGCTATGCCAACAACTCCGAACAGCTCTGTGCCCGTTCGTGGCGTGTCCCACATCG
CTTTGAAGGAGGAATTGTATGTACACCACCAATCAATCAGAATGTTTGA

Upstream 100 bases:

>100_bases
TGACACGCTATCGTGAAGCCGTAACAGGACAACTTCCGGAACATCGCGATTGGATCACATTTGTGAAATCAGCAGTAAAA
GAGTAAAGGAGTTTTGCACG

Downstream 100 bases:

>100_bases
TCGAAGGCGTGTCCGTCCGTGAACTTCAAGCGACGTACGGGACACCCTTGTATATCATGAGTGAGCCAGAACTAGAGCGT
CGCCTCGGAATCGTCCGGGA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MGVTIDLNAIRENKRRIEALGRPVFAVVKNNAYNLGMEPVVTTLYDEGVRHFMVTTLEEALEVRTHAESARVLIMNPVYT
WEHVHAHDFDVAIGSYEWLVSQREHLDGVRLHLKLDVGMNRFGAKTFEEALRIVAFCQNEGLNLVGLCTHFPLADADNAE
VEHSVQVERFADWSTRLMERHTFELIHAANSAATLQDDSRLHHCTHVRVGIFLYGYSSVEPVEWLVPAFYWETEVVAVHD
IEAGAHVGYGTGYTAESKERIAVLPVGYGDGLMRARRHLPVHIEGRAYPFVSNIFMSHSFIKVDEDVQIGDRVALYGIET
KIDDVTRVGYANNSEQLCARSWRVPHRFEGGIVCTPPINQNV

Sequences:

>Translated_362_residues
MGVTIDLNAIRENKRRIEALGRPVFAVVKNNAYNLGMEPVVTTLYDEGVRHFMVTTLEEALEVRTHAESARVLIMNPVYT
WEHVHAHDFDVAIGSYEWLVSQREHLDGVRLHLKLDVGMNRFGAKTFEEALRIVAFCQNEGLNLVGLCTHFPLADADNAE
VEHSVQVERFADWSTRLMERHTFELIHAANSAATLQDDSRLHHCTHVRVGIFLYGYSSVEPVEWLVPAFYWETEVVAVHD
IEAGAHVGYGTGYTAESKERIAVLPVGYGDGLMRARRHLPVHIEGRAYPFVSNIFMSHSFIKVDEDVQIGDRVALYGIET
KIDDVTRVGYANNSEQLCARSWRVPHRFEGGIVCTPPINQNV
>Mature_361_residues
GVTIDLNAIRENKRRIEALGRPVFAVVKNNAYNLGMEPVVTTLYDEGVRHFMVTTLEEALEVRTHAESARVLIMNPVYTW
EHVHAHDFDVAIGSYEWLVSQREHLDGVRLHLKLDVGMNRFGAKTFEEALRIVAFCQNEGLNLVGLCTHFPLADADNAEV
EHSVQVERFADWSTRLMERHTFELIHAANSAATLQDDSRLHHCTHVRVGIFLYGYSSVEPVEWLVPAFYWETEVVAVHDI
EAGAHVGYGTGYTAESKERIAVLPVGYGDGLMRARRHLPVHIEGRAYPFVSNIFMSHSFIKVDEDVQIGDRVALYGIETK
IDDVTRVGYANNSEQLCARSWRVPHRFEGGIVCTPPINQNV

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=371, Percent_Identity=29.3800539083558, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790487, Length=365, Percent_Identity=29.041095890411, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 40919; Mature: 40788

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVTIDLNAIRENKRRIEALGRPVFAVVKNNAYNLGMEPVVTTLYDEGVRHFMVTTLEEA
CCEEEEHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LEVRTHAESARVLIMNPVYTWEHVHAHDFDVAIGSYEWLVSQREHLDGVRLHLKLDVGMN
HHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCEEEEEEEEECCCC
RFGAKTFEEALRIVAFCQNEGLNLVGLCTHFPLADADNAEVEHSVQVERFADWSTRLMER
CCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHEEEHHHHHHHHHHHHHH
HTFELIHAANSAATLQDDSRLHHCTHVRVGIFLYGYSSVEPVEWLVPAFYWETEVVAVHD
HHHHHHHHCCCCCEECCCCCHHHEEEEEEEEEEEECCCCCHHHHHHHHHEECEEEEEEEE
IEAGAHVGYGTGYTAESKERIAVLPVGYGDGLMRARRHLPVHIEGRAYPFVSNIFMSHSF
CCCCCEECCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCEEECCCCCCHHHHHHHCCCE
IKVDEDVQIGDRVALYGIETKIDDVTRVGYANNSEQLCARSWRVPHRFEGGIVCTPPINQ
EEECCCCCCCCEEEEEEECCCCCHHHEECCCCCHHHHHHHHCCCCCCCCCCEEECCCCCC
NV
CC
>Mature Secondary Structure 
GVTIDLNAIRENKRRIEALGRPVFAVVKNNAYNLGMEPVVTTLYDEGVRHFMVTTLEEA
CEEEEHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LEVRTHAESARVLIMNPVYTWEHVHAHDFDVAIGSYEWLVSQREHLDGVRLHLKLDVGMN
HHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCEEEEEEEEECCCC
RFGAKTFEEALRIVAFCQNEGLNLVGLCTHFPLADADNAEVEHSVQVERFADWSTRLMER
CCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHEEEHHHHHHHHHHHHHH
HTFELIHAANSAATLQDDSRLHHCTHVRVGIFLYGYSSVEPVEWLVPAFYWETEVVAVHD
HHHHHHHHCCCCCEECCCCCHHHEEEEEEEEEEEECCCCCHHHHHHHHHEECEEEEEEEE
IEAGAHVGYGTGYTAESKERIAVLPVGYGDGLMRARRHLPVHIEGRAYPFVSNIFMSHSF
CCCCCEECCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCEEECCCCCCHHHHHHHCCCE
IKVDEDVQIGDRVALYGIETKIDDVTRVGYANNSEQLCARSWRVPHRFEGGIVCTPPINQ
EEECCCCCCCCEEEEEEECCCCCHHHEECCCCCHHHHHHHHCCCCCCCCCCEEECCCCCC
NV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11447207 [H]