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The map label for this gene is regX3 [H]

Identifier: 229917599

GI number: 229917599

Start: 1840664

End: 1841314

Strand: Direct

Name: regX3 [H]

Synonym: EAT1b_1874

Alternate gene names: 229917599

Gene position: 1840664-1841314 (Clockwise)

Preceding gene: 229917597

Following gene: 229917600

Centisome position: 61.36

GC content: 49.16

Gene sequence:

>651_bases
ATGAACGTACTCGTTGTGGAAGATGAACTAAAACTGGCGGACGGCATGTCCCGCTTTTTAACATATTCCGGATTTGAGGT
GACCGTGGCGATGACTTTGAGTGAGGCGAAGCAACAGTTACATCAACGGTTTGATGCGGTCTTATTGGATGTCCGTCTCC
CTGACGGAGAAGGCTGGACCTTGATTCCGACATTGAAAGCGCAACATCCTACACCCGCTATCATCTTGACGACGGCCCGC
GGTGAGGCAGATGACCGCGTGTTCGGATTGGAACTTGGCGCAGACGATTATTTAGTCAAACCCATCGTGTTAAAAGAGTT
GGAGATTCGATTGAAGCGTCTCGTGAAACAGACGGATATGATTCAGTTCGGGGCGCTCACCATCGACGTCAAATCGAGAA
TGGTACAAGAGAACGGACATCCGCTTCGACTGACGAATAAAGAGTATGAATTGCTACTGTATCTTTGGAAACATGTCGGG
GAGGCGTTAGACCGGAACCGTTTGCTCGACGACGTATGGGATTACGCATTCGTCGGAGATACACGAACGGTCGACACCCA
TATTAAACAACTGCGGGACAAATCGCCGACCTTAAAAGAACAATTGAAGACCGTTCATCGGGTCGGTTATCGATTAGAGG
GACTGTCATGA

Upstream 100 bases:

>100_bases
TTAGAAGTTGTGAGGGAGTTGCAAGATTTCTGCAAATTGTCTTTGGGAAACGGTGGGACGTTCGATGGGTACGATATAAT
GGAGGTGGAGGCGATATGAG

Downstream 100 bases:

>100_bases
ATCGATTAATGAAGAAGTTACTTTGGACGGCCATTCTACCACTTGCCGTGATGGCACTTTTAACATTCGGACTCACGTCA
TTATTGATCGGACGCTTCGC

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MNVLVVEDELKLADGMSRFLTYSGFEVTVAMTLSEAKQQLHQRFDAVLLDVRLPDGEGWTLIPTLKAQHPTPAIILTTAR
GEADDRVFGLELGADDYLVKPIVLKELEIRLKRLVKQTDMIQFGALTIDVKSRMVQENGHPLRLTNKEYELLLYLWKHVG
EALDRNRLLDDVWDYAFVGDTRTVDTHIKQLRDKSPTLKEQLKTVHRVGYRLEGLS

Sequences:

>Translated_216_residues
MNVLVVEDELKLADGMSRFLTYSGFEVTVAMTLSEAKQQLHQRFDAVLLDVRLPDGEGWTLIPTLKAQHPTPAIILTTAR
GEADDRVFGLELGADDYLVKPIVLKELEIRLKRLVKQTDMIQFGALTIDVKSRMVQENGHPLRLTNKEYELLLYLWKHVG
EALDRNRLLDDVWDYAFVGDTRTVDTHIKQLRDKSPTLKEQLKTVHRVGYRLEGLS
>Mature_216_residues
MNVLVVEDELKLADGMSRFLTYSGFEVTVAMTLSEAKQQLHQRFDAVLLDVRLPDGEGWTLIPTLKAQHPTPAIILTTAR
GEADDRVFGLELGADDYLVKPIVLKELEIRLKRLVKQTDMIQFGALTIDVKSRMVQENGHPLRLTNKEYELLLYLWKHVG
EALDRNRLLDDVWDYAFVGDTRTVDTHIKQLRDKSPTLKEQLKTVHRVGYRLEGLS

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=37.7777777777778, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=36.8421052631579, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=35.2941176470588, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=32.2727272727273, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=33.7777777777778, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=33.7899543378995, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1789809, Length=224, Percent_Identity=29.4642857142857, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=31.1926605504587, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=31.0810810810811, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI2367329, Length=224, Percent_Identity=33.4821428571429, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=34.5132743362832, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=30.1724137931034, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=28.0542986425339, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790437, Length=122, Percent_Identity=30.327868852459, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24724; Mature: 24724

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLVVEDELKLADGMSRFLTYSGFEVTVAMTLSEAKQQLHQRFDAVLLDVRLPDGEGWT
CEEEEEECHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHEEEEEECCCCCCEE
LIPTLKAQHPTPAIILTTARGEADDRVFGLELGADDYLVKPIVLKELEIRLKRLVKQTDM
EEEECCCCCCCCEEEEEECCCCCCCEEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHCC
IQFGALTIDVKSRMVQENGHPLRLTNKEYELLLYLWKHVGEALDRNRLLDDVWDYAFVGD
EEECEEEEHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
TRTVDTHIKQLRDKSPTLKEQLKTVHRVGYRLEGLS
CCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNVLVVEDELKLADGMSRFLTYSGFEVTVAMTLSEAKQQLHQRFDAVLLDVRLPDGEGWT
CEEEEEECHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHEEEEEECCCCCCEE
LIPTLKAQHPTPAIILTTARGEADDRVFGLELGADDYLVKPIVLKELEIRLKRLVKQTDM
EEEECCCCCCCCEEEEEECCCCCCCEEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHCC
IQFGALTIDVKSRMVQENGHPLRLTNKEYELLLYLWKHVGEALDRNRLLDDVWDYAFVGD
EEECEEEEHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
TRTVDTHIKQLRDKSPTLKEQLKTVHRVGYRLEGLS
CCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA