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The map label for this gene is dgk [H]

Identifier: 229917438

GI number: 229917438

Start: 1671790

End: 1672425

Strand: Direct

Name: dgk [H]

Synonym: EAT1b_1713

Alternate gene names: 229917438

Gene position: 1671790-1672425 (Clockwise)

Preceding gene: 229917423

Following gene: 229917439

Centisome position: 55.73

GC content: 41.82

Gene sequence:

>636_bases
ATGTTTATAACGGTAGAAGGACCGATTGGTGTCGGGAAAACATCACTGGCCCATATCATCAGTCAGCATTTCTCGATGCA
GATGCTGAATGAAATTGTAGAAGAGAACCCATTTCTCGGCAAGTTTTATGAAGATATCGAAGAATGGAGTTTCCAAACGG
AAATGTTCTTCTTGTGCAATCGATTCAAGCAGTTGGATGATATTCACAAACACCACTTGAGTCAGCAACAATCCGTCGTT
TCGGACTATCATATTTTCAAAAACTTGATTTTTGCTCACCGTTCGCTGAAACCGGCACACTTGAACAAGTACGAGCAGAT
TTATAAGATTTTGACACATGATATGCCGAAACCTGATGTCGTCATTTACTTACATGCCAGCATTGAGACATTAATGAAAC
GAGTCGCCTTGCGTGGACGTGAAGTGGAAGAGAATATGTCTCGTGATTACCTCGAACAACTTGCTCACGACTATGAGACG
TTTGTTGAATCATATCGCGCGGCCCATCCAGAAGTGAAAATCCTCTCGTTCAGTGGGGATGAACTCGACTTTGTACACAA
TCCGGACGACTTGACTCATGTCCTAAAAACGATTGAGCGTGAATTAGAATTAACTAAAGGAGCCCAAATAAAATGA

Upstream 100 bases:

>100_bases
TAAAACTATGAAAAAAAATGAAAATCAAATCCCTCGCCATATCGCTCGTATTGTGTGCTAGAATGGAACTTGCACTTTGG
ATAATGGAGGATGACATCAT

Downstream 100 bases:

>100_bases
AGCTGATTGATAAATATAACATCCCGAACGATACGATCATTACAATCGGTGGAATGGTTGGGATCGGGAAATCAACGATC
ACCAATTCGTTAGCCGATGC

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MFITVEGPIGVGKTSLAHIISQHFSMQMLNEIVEENPFLGKFYEDIEEWSFQTEMFFLCNRFKQLDDIHKHHLSQQQSVV
SDYHIFKNLIFAHRSLKPAHLNKYEQIYKILTHDMPKPDVVIYLHASIETLMKRVALRGREVEENMSRDYLEQLAHDYET
FVESYRAAHPEVKILSFSGDELDFVHNPDDLTHVLKTIERELELTKGAQIK

Sequences:

>Translated_211_residues
MFITVEGPIGVGKTSLAHIISQHFSMQMLNEIVEENPFLGKFYEDIEEWSFQTEMFFLCNRFKQLDDIHKHHLSQQQSVV
SDYHIFKNLIFAHRSLKPAHLNKYEQIYKILTHDMPKPDVVIYLHASIETLMKRVALRGREVEENMSRDYLEQLAHDYET
FVESYRAAHPEVKILSFSGDELDFVHNPDDLTHVLKTIERELELTKGAQIK
>Mature_211_residues
MFITVEGPIGVGKTSLAHIISQHFSMQMLNEIVEENPFLGKFYEDIEEWSFQTEMFFLCNRFKQLDDIHKHHLSQQQSVV
SDYHIFKNLIFAHRSLKPAHLNKYEQIYKILTHDMPKPDVVIYLHASIETLMKRVALRGREVEENMSRDYLEQLAHDYET
FVESYRAAHPEVKILSFSGDELDFVHNPDDLTHVLKTIERELELTKGAQIK

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 24818; Mature: 24818

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFITVEGPIGVGKTSLAHIISQHFSMQMLNEIVEENPFLGKFYEDIEEWSFQTEMFFLCN
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
RFKQLDDIHKHHLSQQQSVVSDYHIFKNLIFAHRSLKPAHLNKYEQIYKILTHDMPKPDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCE
VIYLHASIETLMKRVALRGREVEENMSRDYLEQLAHDYETFVESYRAAHPEVKILSFSGD
EEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
ELDFVHNPDDLTHVLKTIERELELTKGAQIK
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFITVEGPIGVGKTSLAHIISQHFSMQMLNEIVEENPFLGKFYEDIEEWSFQTEMFFLCN
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
RFKQLDDIHKHHLSQQQSVVSDYHIFKNLIFAHRSLKPAHLNKYEQIYKILTHDMPKPDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCE
VIYLHASIETLMKRVALRGREVEENMSRDYLEQLAHDYETFVESYRAAHPEVKILSFSGD
EEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
ELDFVHNPDDLTHVLKTIERELELTKGAQIK
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]