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The map label for this gene is pabA [H]

Identifier: 229917396

GI number: 229917396

Start: 1618408

End: 1618992

Strand: Reverse

Name: pabA [H]

Synonym: EAT1b_1671

Alternate gene names: 229917396

Gene position: 1618992-1618408 (Counterclockwise)

Preceding gene: 229917397

Following gene: 229917395

Centisome position: 53.97

GC content: 48.89

Gene sequence:

>585_bases
ATGATTGTATTGATCGACAACTATGACTCATTTACGTATAACTTGGTGCAATATTTCGGTGAACTCGGTCAAGAACTGGT
CGTGTATCGAAACGATGAAGTCACGATTCAAGAGATTGAGGCGCTTGCCCCGAGTTATCTTGTCATTTCGCCGGGACCTT
GCACTCCGAATGAGGCGGGAATTAGCGTTGAGGCAATCCGAGCGTTCGCAGGTCGTATCCCGATTTTAGGGGTTTGTCTC
GGGCATCAGGCGATTGCGCAAGCGTTCGGCGGAGAAGTTGTCCATGCGGAGCGGCTCATGCATGGAAAAACGTCGAAGAT
TCAACATGACGGAAAATCGATTTTCAAGGAGATTCCACAACAGACGATTGTGACCCGTTATCATTCGTTGGCCGTGGAGC
GTTCGTCTCTACCAGAATGTCTAGTGGTCACTGCAGAGACGGAGACTGGAGAAATCATGGCACTCCGTCACCGAACGCTT
TCGATCGAAGGGGTGCAATATCACCCTGAAGCGATTTTGACTGAGCACGGGAAGGAAATGATTCGAAACTTTATCGAGGA
GTATCGTCATGTGGTATTGGCATAA

Upstream 100 bases:

>100_bases
CAGGTATCGTGATTGATTCGGATCCGGTCTCGGAATATGAAGAATCCCTGTCCAAAGCGAAGGCGCTATGGGCGGCGAAA
CACATGACGGAGGAAACGAC

Downstream 100 bases:

>100_bases
TGGAGAGTTAGTCGAACGAGAGAAGGTGTTGATTCCGGTTGAAGATCACGGCTTCTTGTATGGAATGGGCTTGTTCGAGA
CGTTCCGTACATATGAATTC

Product: glutamine amidotransferase of anthranilate synthase

Products: NA

Alternate protein names: Para-aminobenzoate synthase glutamine amidotransferase component II; ADC synthase; Anthranilate synthase component II [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MIVLIDNYDSFTYNLVQYFGELGQELVVYRNDEVTIQEIEALAPSYLVISPGPCTPNEAGISVEAIRAFAGRIPILGVCL
GHQAIAQAFGGEVVHAERLMHGKTSKIQHDGKSIFKEIPQQTIVTRYHSLAVERSSLPECLVVTAETETGEIMALRHRTL
SIEGVQYHPEAILTEHGKEMIRNFIEEYRHVVLA

Sequences:

>Translated_194_residues
MIVLIDNYDSFTYNLVQYFGELGQELVVYRNDEVTIQEIEALAPSYLVISPGPCTPNEAGISVEAIRAFAGRIPILGVCL
GHQAIAQAFGGEVVHAERLMHGKTSKIQHDGKSIFKEIPQQTIVTRYHSLAVERSSLPECLVVTAETETGEIMALRHRTL
SIEGVQYHPEAILTEHGKEMIRNFIEEYRHVVLA
>Mature_194_residues
MIVLIDNYDSFTYNLVQYFGELGQELVVYRNDEVTIQEIEALAPSYLVISPGPCTPNEAGISVEAIRAFAGRIPILGVCL
GHQAIAQAFGGEVVHAERLMHGKTSKIQHDGKSIFKEIPQQTIVTRYHSLAVERSSLPECLVVTAETETGEIMALRHRTL
SIEGVQYHPEAILTEHGKEMIRNFIEEYRHVVLA

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine and also involved in the synthesis of anthranilate [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=61.6216216216216, Blast_Score=254, Evalue=2e-69,
Organism=Escherichia coli, GI1787517, Length=183, Percent_Identity=41.5300546448087, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788854, Length=201, Percent_Identity=25.3731343283582, Blast_Score=65, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=186, Percent_Identity=55.3763440860215, Blast_Score=221, Evalue=4e-59,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=28.9099526066351, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323873, Length=193, Percent_Identity=28.4974093264249, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85; =4.1.3.27 [H]

Molecular weight: Translated: 21644; Mature: 21644

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLIDNYDSFTYNLVQYFGELGQELVVYRNDEVTIQEIEALAPSYLVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCEEEEECCCCCCCCCC
ISVEAIRAFAGRIPILGVCLGHQAIAQAFGGEVVHAERLMHGKTSKIQHDGKSIFKEIPQ
CHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCH
QTIVTRYHSLAVERSSLPECLVVTAETETGEIMALRHRTLSIEGVQYHPEAILTEHGKEM
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEEEEECCCEECCHHHHHHHHHHH
IRNFIEEYRHVVLA
HHHHHHHHHHHHCC
>Mature Secondary Structure
MIVLIDNYDSFTYNLVQYFGELGQELVVYRNDEVTIQEIEALAPSYLVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCEEEEECCCCCCCCCC
ISVEAIRAFAGRIPILGVCLGHQAIAQAFGGEVVHAERLMHGKTSKIQHDGKSIFKEIPQ
CHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCH
QTIVTRYHSLAVERSSLPECLVVTAETETGEIMALRHRTLSIEGVQYHPEAILTEHGKEM
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEEEEEECCCEECCHHHHHHHHHHH
IRNFIEEYRHVVLA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]