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The map label for this gene is pabC [H]

Identifier: 229917395

GI number: 229917395

Start: 1617606

End: 1618424

Strand: Reverse

Name: pabC [H]

Synonym: EAT1b_1670

Alternate gene names: 229917395

Gene position: 1618424-1617606 (Counterclockwise)

Preceding gene: 229917396

Following gene: 229917394

Centisome position: 53.95

GC content: 49.94

Gene sequence:

>819_bases
ATGTGGTATTGGCATAATGGAGAGTTAGTCGAACGAGAGAAGGTGTTGATTCCGGTTGAAGATCACGGCTTCTTGTATGG
AATGGGCTTGTTCGAGACGTTCCGTACATATGAATTCGTTCCTTTCCTGTTCGATGCCCACTGGGAGCGCTTGATGAAGA
GTCTCGATGAGCTGTGGATCGATTTTCCATACACGAAAGAAGAAATCGGGACGGCGATTCAGCAACTGTGCCGTCAAAAC
GATGCACCCGACCTTTATATCCGCTTGAACGTGTCGGCAGGAGTTGCGCCCCTCGGTCTCTACGCGGGTCGTTATGAGAC
ACCGAACGTCACCATGATTGTCAAACCGCTATCCTCAGAAGTTGTGCCACAGGAGAAACGGGTCGAACCGATCCCGTTTC
CGAGAAGTCGTCCTGAAGCGGCTTTTCGATTAAAATCGCATCATTACATGAACAATATCCTTGGGAAACGGACCTTACAA
GACCAGAGTGCTGAAGGACTATTTGCGGACGAGCATGGACGTGTAGTGGAAGGGCTCGTGTCGAACATCTTTTGGGTCGG
TCCAGATGATAGGTTATACACGACTCCGCTCTCGAGCGGAGCACTCGCAGGTGTGACGCGACAATGGGTGATGGACCATT
TCTCTGTAGTCGAACAACCCGTGACATTTGAAGAATTGACTGCAGCGAAAGAGATTTGGATGACGAATTCAATCCAACAA
GTCGCTCCGGTGACGCATTATGGAAATCTGAGATACCCCGGTAAAGACGGGGTACGATTTAACGAAGTGTGGGCGAAACT
CGTTCGCTCACTTGGTTAG

Upstream 100 bases:

>100_bases
CACCGAACGCTTTCGATCGAAGGGGTGCAATATCACCCTGAAGCGATTTTGACTGAGCACGGGAAGGAAATGATTCGAAA
CTTTATCGAGGAGTATCGTC

Downstream 100 bases:

>100_bases
GAGGCGGAAACATGACGAAAATCATGGGTATTTTAAACGTGACCCCGGACTCGTTTTCGGATGGGGGACGGTATACGGCA
ATCGAGGAAGCTGTACGACA

Product: aminotransferase class IV

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MWYWHNGELVEREKVLIPVEDHGFLYGMGLFETFRTYEFVPFLFDAHWERLMKSLDELWIDFPYTKEEIGTAIQQLCRQN
DAPDLYIRLNVSAGVAPLGLYAGRYETPNVTMIVKPLSSEVVPQEKRVEPIPFPRSRPEAAFRLKSHHYMNNILGKRTLQ
DQSAEGLFADEHGRVVEGLVSNIFWVGPDDRLYTTPLSSGALAGVTRQWVMDHFSVVEQPVTFEELTAAKEIWMTNSIQQ
VAPVTHYGNLRYPGKDGVRFNEVWAKLVRSLG

Sequences:

>Translated_272_residues
MWYWHNGELVEREKVLIPVEDHGFLYGMGLFETFRTYEFVPFLFDAHWERLMKSLDELWIDFPYTKEEIGTAIQQLCRQN
DAPDLYIRLNVSAGVAPLGLYAGRYETPNVTMIVKPLSSEVVPQEKRVEPIPFPRSRPEAAFRLKSHHYMNNILGKRTLQ
DQSAEGLFADEHGRVVEGLVSNIFWVGPDDRLYTTPLSSGALAGVTRQWVMDHFSVVEQPVTFEELTAAKEIWMTNSIQQ
VAPVTHYGNLRYPGKDGVRFNEVWAKLVRSLG
>Mature_272_residues
MWYWHNGELVEREKVLIPVEDHGFLYGMGLFETFRTYEFVPFLFDAHWERLMKSLDELWIDFPYTKEEIGTAIQQLCRQN
DAPDLYIRLNVSAGVAPLGLYAGRYETPNVTMIVKPLSSEVVPQEKRVEPIPFPRSRPEAAFRLKSHHYMNNILGKRTLQ
DQSAEGLFADEHGRVVEGLVSNIFWVGPDDRLYTTPLSSGALAGVTRQWVMDHFSVVEQPVTFEELTAAKEIWMTNSIQQ
VAPVTHYGNLRYPGKDGVRFNEVWAKLVRSLG

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=259, Percent_Identity=25.8687258687259, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 31277; Mature: 31277

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWYWHNGELVEREKVLIPVEDHGFLYGMGLFETFRTYEFVPFLFDAHWERLMKSLDELWI
CCEEECCCEEECCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DFPYTKEEIGTAIQQLCRQNDAPDLYIRLNVSAGVAPLGLYAGRYETPNVTMIVKPLSSE
CCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCEEEEEECCCCC
VVPQEKRVEPIPFPRSRPEAAFRLKSHHYMNNILGKRTLQDQSAEGLFADEHGRVVEGLV
CCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHH
SNIFWVGPDDRLYTTPLSSGALAGVTRQWVMDHFSVVEQPVTFEELTAAKEIWMTNSIQQ
HCEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHH
VAPVTHYGNLRYPGKDGVRFNEVWAKLVRSLG
HCCHHHCCCEECCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MWYWHNGELVEREKVLIPVEDHGFLYGMGLFETFRTYEFVPFLFDAHWERLMKSLDELWI
CCEEECCCEEECCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DFPYTKEEIGTAIQQLCRQNDAPDLYIRLNVSAGVAPLGLYAGRYETPNVTMIVKPLSSE
CCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCEEEEEECCCCC
VVPQEKRVEPIPFPRSRPEAAFRLKSHHYMNNILGKRTLQDQSAEGLFADEHGRVVEGLV
CCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHH
SNIFWVGPDDRLYTTPLSSGALAGVTRQWVMDHFSVVEQPVTFEELTAAKEIWMTNSIQQ
HCEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHH
VAPVTHYGNLRYPGKDGVRFNEVWAKLVRSLG
HCCHHHCCCEECCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]