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The map label for this gene is pabB [H]

Identifier: 229917397

GI number: 229917397

Start: 1618989

End: 1620368

Strand: Reverse

Name: pabB [H]

Synonym: EAT1b_1672

Alternate gene names: 229917397

Gene position: 1620368-1618989 (Counterclockwise)

Preceding gene: 229917398

Following gene: 229917396

Centisome position: 54.01

GC content: 52.39

Gene sequence:

>1380_bases
GTGAGATCGACTGCGTTCAGAACAAAGCGGATGACGAAAGAGAAGATGTATGAGGCATACATGACATTGACAGCGGATCA
ACCGTATCATGCATGGTTAGAGAGTGGGAGAGCGGGACGGTATACGATTGCGGGAATCGAGCCGTTCGGTCGCTTTCATG
TAAAAGACGGTGTCGGACTCTTGCAAGTGGGCGATACGACCGAAACACTATACGGAAAGCCGCTTGAGCTCGTCAGTGAG
GTACGGAAGCGATTTGAGGCCGAGCGTCCGGAAGGGGCTCCTCCTTTCTTTGGTGGCATGATTGGGTATGTCAGTTATGA
TGTGGCCCGGACGATTGAACGTCTCCCTGAGCAAGCGGAGGATGATTTGTCGACACCAGACGTCTCGTTTCTTCTGTTTG
ATGAGGTGGCGGTGTTCGATGAAGTGGATTCGACTCTGTACTTGATGGTGACGGCGGAGGAAGGTGCAGAACGTAAGGCG
GACCGATTGGCGGCCATGTGGAACGTCGAGTCGCATTACGCGTTCAAGCCGACAAGGCAGTCATCGGTAGAGCGATCGCG
CTCCATGTCCCAGGAAGAGTTTGTTGAAGCGGTCAAACGGATTCAGTCCTATATCGTAGAAGGGGACGTGTTCCAAGTGA
ACTTGAGCGTTCGGCAGTCTGAACCGCTTCTCGCTGACCCGCGTCGTGTATATGATACGTTGCGACAAATGAATCCATCT
CCTTATATGGGATATTTCGTGGACGACGCTTTGACGATGGTCTCCGCTTCACCAGAGTTGTTGCTTGAAAAACATGGAAC
CGACATTTCGACGCGCCCGATCGCGGGTACGCGTCCACGTGGGAAAGATGATGTGGAAGACCTAGAGTTGGCGAACACGT
TGCTTGAAAACGAGAAAGAGCGAGCAGAACACGTCATGCTCGTCGACCTCGAACGGAACGACCTTGGCAAGGTGGCGGCA
TATGGCAGCGTTCATGTTGATGAATTGATGGTGATTGAGAAATACTCACACGTGCAACATATCGTCTCGAACGTACGGGG
TACGATTCAAGATGAAGTATCAGGAGCCGAAGCGCTGGCAGCGATGTTCCCAGGCGGCACCATCACCGGCGCCCCGAAAA
TTCGGACGATGGAAATCATCGAAGAACTCGAACCAGTTCGCCGGGGACTCTACACCGGTTCATATGGATGGTTAAGTTGG
AATGACGACCTTGTCTTCAATATCACCATTCGAACGATGGTCGTGAAAGACGGAATCGCATACGTTCAAGCGGGAGCAGG
TATCGTGATTGATTCGGATCCGGTCTCGGAATATGAAGAATCCCTGTCCAAAGCGAAGGCGCTATGGGCGGCGAAACACA
TGACGGAGGAAACGACATGA

Upstream 100 bases:

>100_bases
GTATAACATTTCAGGCAGTAATCGAGAGACATTCTCTTTCGATTGCTGCCTTTTCTTGTGTACAATAAAAGGCATGAATG
AATAGACGGAGGAATGACAT

Downstream 100 bases:

>100_bases
TTGTATTGATCGACAACTATGACTCATTTACGTATAACTTGGTGCAATATTTCGGTGAACTCGGTCAAGAACTGGTCGTG
TATCGAAACGATGAAGTCAC

Product: Anthranilate synthase

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MRSTAFRTKRMTKEKMYEAYMTLTADQPYHAWLESGRAGRYTIAGIEPFGRFHVKDGVGLLQVGDTTETLYGKPLELVSE
VRKRFEAERPEGAPPFFGGMIGYVSYDVARTIERLPEQAEDDLSTPDVSFLLFDEVAVFDEVDSTLYLMVTAEEGAERKA
DRLAAMWNVESHYAFKPTRQSSVERSRSMSQEEFVEAVKRIQSYIVEGDVFQVNLSVRQSEPLLADPRRVYDTLRQMNPS
PYMGYFVDDALTMVSASPELLLEKHGTDISTRPIAGTRPRGKDDVEDLELANTLLENEKERAEHVMLVDLERNDLGKVAA
YGSVHVDELMVIEKYSHVQHIVSNVRGTIQDEVSGAEALAAMFPGGTITGAPKIRTMEIIEELEPVRRGLYTGSYGWLSW
NDDLVFNITIRTMVVKDGIAYVQAGAGIVIDSDPVSEYEESLSKAKALWAAKHMTEETT

Sequences:

>Translated_459_residues
MRSTAFRTKRMTKEKMYEAYMTLTADQPYHAWLESGRAGRYTIAGIEPFGRFHVKDGVGLLQVGDTTETLYGKPLELVSE
VRKRFEAERPEGAPPFFGGMIGYVSYDVARTIERLPEQAEDDLSTPDVSFLLFDEVAVFDEVDSTLYLMVTAEEGAERKA
DRLAAMWNVESHYAFKPTRQSSVERSRSMSQEEFVEAVKRIQSYIVEGDVFQVNLSVRQSEPLLADPRRVYDTLRQMNPS
PYMGYFVDDALTMVSASPELLLEKHGTDISTRPIAGTRPRGKDDVEDLELANTLLENEKERAEHVMLVDLERNDLGKVAA
YGSVHVDELMVIEKYSHVQHIVSNVRGTIQDEVSGAEALAAMFPGGTITGAPKIRTMEIIEELEPVRRGLYTGSYGWLSW
NDDLVFNITIRTMVVKDGIAYVQAGAGIVIDSDPVSEYEESLSKAKALWAAKHMTEETT
>Mature_459_residues
MRSTAFRTKRMTKEKMYEAYMTLTADQPYHAWLESGRAGRYTIAGIEPFGRFHVKDGVGLLQVGDTTETLYGKPLELVSE
VRKRFEAERPEGAPPFFGGMIGYVSYDVARTIERLPEQAEDDLSTPDVSFLLFDEVAVFDEVDSTLYLMVTAEEGAERKA
DRLAAMWNVESHYAFKPTRQSSVERSRSMSQEEFVEAVKRIQSYIVEGDVFQVNLSVRQSEPLLADPRRVYDTLRQMNPS
PYMGYFVDDALTMVSASPELLLEKHGTDISTRPIAGTRPRGKDDVEDLELANTLLENEKERAEHVMLVDLERNDLGKVAA
YGSVHVDELMVIEKYSHVQHIVSNVRGTIQDEVSGAEALAAMFPGGTITGAPKIRTMEIIEELEPVRRGLYTGSYGWLSW
NDDLVFNITIRTMVVKDGIAYVQAGAGIVIDSDPVSEYEESLSKAKALWAAKHMTEETT

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=442, Percent_Identity=33.4841628959276, Blast_Score=251, Evalue=7e-68,
Organism=Escherichia coli, GI1787518, Length=380, Percent_Identity=38.4210526315789, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1786809, Length=262, Percent_Identity=28.2442748091603, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082077, Length=215, Percent_Identity=25.5813953488372, Blast_Score=75, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6320935, Length=467, Percent_Identity=36.4025695931477, Blast_Score=251, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6324361, Length=390, Percent_Identity=25.6410256410256, Blast_Score=125, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 51542; Mature: 51542

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSTAFRTKRMTKEKMYEAYMTLTADQPYHAWLESGRAGRYTIAGIEPFGRFHVKDGVGL
CCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHCCCCCCEEEEECCCCCCEEECCCCEE
LQVGDTTETLYGKPLELVSEVRKRFEAERPEGAPPFFGGMIGYVSYDVARTIERLPEQAE
EEECCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DDLSTPDVSFLLFDEVAVFDEVDSTLYLMVTAEEGAERKADRLAAMWNVESHYAFKPTRQ
CCCCCCCCEEEEHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEECCCHH
SSVERSRSMSQEEFVEAVKRIQSYIVEGDVFQVNLSVRQSEPLLADPRRVYDTLRQMNPS
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCHHHHHHHHHCCCC
PYMGYFVDDALTMVSASPELLLEKHGTDISTRPIAGTRPRGKDDVEDLELANTLLENEKE
CCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHH
RAEHVMLVDLERNDLGKVAAYGSVHVDELMVIEKYSHVQHIVSNVRGTIQDEVSGAEALA
HCCEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AMFPGGTITGAPKIRTMEIIEELEPVRRGLYTGSYGWLSWNDDLVFNITIRTMVVKDGIA
HHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEEEEEEECCCHH
YVQAGAGIVIDSDPVSEYEESLSKAKALWAAKHMTEETT
EEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRSTAFRTKRMTKEKMYEAYMTLTADQPYHAWLESGRAGRYTIAGIEPFGRFHVKDGVGL
CCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHCCCCCCEEEEECCCCCCEEECCCCEE
LQVGDTTETLYGKPLELVSEVRKRFEAERPEGAPPFFGGMIGYVSYDVARTIERLPEQAE
EEECCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DDLSTPDVSFLLFDEVAVFDEVDSTLYLMVTAEEGAERKADRLAAMWNVESHYAFKPTRQ
CCCCCCCCEEEEHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEECCCHH
SSVERSRSMSQEEFVEAVKRIQSYIVEGDVFQVNLSVRQSEPLLADPRRVYDTLRQMNPS
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCHHHHHHHHHCCCC
PYMGYFVDDALTMVSASPELLLEKHGTDISTRPIAGTRPRGKDDVEDLELANTLLENEKE
CCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHH
RAEHVMLVDLERNDLGKVAAYGSVHVDELMVIEKYSHVQHIVSNVRGTIQDEVSGAEALA
HCCEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AMFPGGTITGAPKIRTMEIIEELEPVRRGLYTGSYGWLSWNDDLVFNITIRTMVVKDGIA
HHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEEEEEEECCCHH
YVQAGAGIVIDSDPVSEYEESLSKAKALWAAKHMTEETT
EEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]