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The map label for this gene is mtnD [H]

Identifier: 229917165

GI number: 229917165

Start: 1407055

End: 1407588

Strand: Direct

Name: mtnD [H]

Synonym: EAT1b_1439

Alternate gene names: 229917165

Gene position: 1407055-1407588 (Clockwise)

Preceding gene: 229917164

Following gene: 229917167

Centisome position: 46.9

GC content: 47.19

Gene sequence:

>534_bases
ATGGCAACGATTTATTTTCAACAAACCGAAGAACGTGTCAGCGACCAACAAGAGGTACGTGACTTTTTAGAATCACGAGA
CATTCTTTACGAAGCGTGGGACATCACGAAATTACCGGTTTCCCTTCAAGAAAATTATCAACTGACAGACGAGGACAAAG
AAGCCATCTTGGCGACGTTCCGTGACGAGATTCAAGATGTGTCGGCACGACGCGGCTACAAGACGGCTGACGTCATCTCA
CTATCCGACGCGACACCGAATTTAGATGAACTGCTCGTCAACTTTCAAAAAGAGCATCACCATACGGATGACGAAGTTCG
CTTCATCGTCAGTGGTCACGGCATTTTTGCCATCGACGATGCAGAACGCGGATACTTCAATATCGAACTCAATCCAGGTG
ATCTCATCTCCGTGCCGGTCAACACACGTCATTACTTCACGTTACAAGAAGACCGCCAAGTCGTCGCCGTTCGTATTTTC
GTGACGACTGAAGGCTGGGTACCGATTTACGACAAAGAGAATGTAACTGCATAA

Upstream 100 bases:

>100_bases
CCCGCTGCGGCAAAACGTTACTTAGAGGCATATGAATTTTTGTTTAGCTATTCATTAAAATTACGCGCCTTAGGCGTCCA
TTCATAAGGAGGAATTCAAC

Downstream 100 bases:

>100_bases
GAAAAGGTCTCTCGCTTAAAAACGAGAGACCACTTTTTATTGTTTGACCGCTGTCGGTTTCGATGAGAACCAGCCCCATG
TCGCAATCCCGACCATGACT

Product: Acireductone dioxygenase ARD

Products: NA

Alternate protein names: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; DHK-MTPene dioxygenase; Acireductone dioxygenase (Fe(2+)-requiring); ARD'; Fe-ARD; Acireductone dioxygenase (Ni(2+)-requiring); ARD; Ni-ARD [H]

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MATIYFQQTEERVSDQQEVRDFLESRDILYEAWDITKLPVSLQENYQLTDEDKEAILATFRDEIQDVSARRGYKTADVIS
LSDATPNLDELLVNFQKEHHHTDDEVRFIVSGHGIFAIDDAERGYFNIELNPGDLISVPVNTRHYFTLQEDRQVVAVRIF
VTTEGWVPIYDKENVTA

Sequences:

>Translated_177_residues
MATIYFQQTEERVSDQQEVRDFLESRDILYEAWDITKLPVSLQENYQLTDEDKEAILATFRDEIQDVSARRGYKTADVIS
LSDATPNLDELLVNFQKEHHHTDDEVRFIVSGHGIFAIDDAERGYFNIELNPGDLISVPVNTRHYFTLQEDRQVVAVRIF
VTTEGWVPIYDKENVTA
>Mature_176_residues
ATIYFQQTEERVSDQQEVRDFLESRDILYEAWDITKLPVSLQENYQLTDEDKEAILATFRDEIQDVSARRGYKTADVISL
SDATPNLDELLVNFQKEHHHTDDEVRFIVSGHGIFAIDDAERGYFNIELNPGDLISVPVNTRHYFTLQEDRQVVAVRIFV
TTEGWVPIYDKENVTA

Specific function: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- me

COG id: COG1791

COG function: function code S; Uncharacterized conserved protein, contains double-stranded beta-helix domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acireductone dioxygenase (ARD) family [H]

Homologues:

Organism=Homo sapiens, GI171460928, Length=106, Percent_Identity=33.9622641509434, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323651, Length=114, Percent_Identity=28.9473684210526, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI161082987, Length=106, Percent_Identity=35.8490566037736, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004313
- InterPro:   IPR011051
- InterPro:   IPR014710 [H]

Pfam domain/function: PF03079 ARD [H]

EC number: =1.13.11.54; =1.13.11.53 [H]

Molecular weight: Translated: 20529; Mature: 20398

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIYFQQTEERVSDQQEVRDFLESRDILYEAWDITKLPVSLQENYQLTDEDKEAILATF
CEEEEEECHHHHCCCHHHHHHHHHCCCCEEEECCCEECCEEECCCCCCCCCHHHHHHHHH
RDEIQDVSARRGYKTADVISLSDATPNLDELLVNFQKEHHHTDDEVRFIVSGHGIFAIDD
HHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEC
AERGYFNIELNPGDLISVPVNTRHYFTLQEDRQVVAVRIFVTTEGWVPIYDKENVTA
CCCCEEEEEECCCCEEEEECCCEEEEEECCCCEEEEEEEEEEECCCEEEECCCCCCC
>Mature Secondary Structure 
ATIYFQQTEERVSDQQEVRDFLESRDILYEAWDITKLPVSLQENYQLTDEDKEAILATF
EEEEEECHHHHCCCHHHHHHHHHCCCCEEEECCCEECCEEECCCCCCCCCHHHHHHHHH
RDEIQDVSARRGYKTADVISLSDATPNLDELLVNFQKEHHHTDDEVRFIVSGHGIFAIDD
HHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEC
AERGYFNIELNPGDLISVPVNTRHYFTLQEDRQVVAVRIFVTTEGWVPIYDKENVTA
CCCCEEEEEECCCCEEEEECCCEEEEEECCCCEEEEEEEEEEECCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA