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The map label for this gene is folE2

Identifier: 229917167

GI number: 229917167

Start: 1408710

End: 1409621

Strand: Direct

Name: folE2

Synonym: EAT1b_1441

Alternate gene names: 229917167

Gene position: 1408710-1409621 (Clockwise)

Preceding gene: 229917165

Following gene: 229917171

Centisome position: 46.96

GC content: 49.56

Gene sequence:

>912_bases
ATGTCTACAAGCCATGTCGCTTTACCTACTAAAGCAGAACGACATAAATTGTTCGGGTCGGTCCCACCGATTAAAGGAAC
AAAGCCGACCGAGAAAGAACAAATGGTCGATTTACAAAATACACCGAAAAACTTCTTGTTCGCCCTCGACAGTGTCGGCA
TCTCAAACGTGAAACACCCTGTGAACGTCGAAACGCCAGAAGGAGTCCAATCTACGGTCGCTACATTCGAATTGACGACA
TCGCTCGTTCAAGATCGTAAAGGGATTAACATGTCTCGTTTGACGGAACAGCTCGATGCGTACCATCAACAAGGGTGGAC
GGTATCGAACCGTTCGTTAATCGAGTTCGCACAGGAGCTTGCCGAGCGGATGGAACAAACGGAAGGTCAATTGACAATCC
GTTACCCATGGTTCTTCACGCGTAAAGCACCTGCGACAGGTCTTAGCGGTTTGATGAACGCCGATGTCATGCACCGTGTG
ACTTACAACCTTGAAACAGGCGTCGCAAACGTGACAGTCGGTCTCGTCATCAACGTCACGACGCTTTGCCCATGTTCAAA
AGAAATCAGTGAATACAGTGCCCATAACCAACGTGGATACATCACGATCGAAGCAGGTCTTGACGAGACGTCAATGGACG
GATTCGACTGGCGTGCAGCCCTTCTCGATGCAGCGGAGTCAAACGCCTCAGCACCACTTCATCCTGTCCTCAAACGTCCG
GATGAGAAACGTGCGACTGAAATCGCATACGAAAATCCACGTTTCGTCGAGGACATGGTCCGCTTGATCGCGGCTGACTT
GTACGAGATGAAACAAGTCGTGAACTTCTTCGTCGAATGCCGTAACGAAGAGTCGATTCACCAACACGATGCCATCGCAT
CGATCACATTCGATAAGCGTCAAGACGCATAA

Upstream 100 bases:

>100_bases
TATGAGAGCAAAATCATACCCGTTCAGCCATCATTTCGTGATAAAATCCTAACAAGAACGAGTGGTCCTTTGAACCGCTC
GAAAAAAGGAGAATCCGATT

Downstream 100 bases:

>100_bases
AAAATGCGGAACCTCTGTTAAAGAAGGTTCCGCATTTTTTATAGACTTGTCACGAGTTCAATTGTCAACAGGATGATGAT
GAGCATCACCCACACTGCCC

Product: GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSTSHVALPTKAERHKLFGSVPPIKGTKPTEKEQMVDLQNTPKNFLFALDSVGISNVKHPVNVETPEGVQSTVATFELTT
SLVQDRKGINMSRLTEQLDAYHQQGWTVSNRSLIEFAQELAERMEQTEGQLTIRYPWFFTRKAPATGLSGLMNADVMHRV
TYNLETGVANVTVGLVINVTTLCPCSKEISEYSAHNQRGYITIEAGLDETSMDGFDWRAALLDAAESNASAPLHPVLKRP
DEKRATEIAYENPRFVEDMVRLIAADLYEMKQVVNFFVECRNEESIHQHDAIASITFDKRQDA

Sequences:

>Translated_303_residues
MSTSHVALPTKAERHKLFGSVPPIKGTKPTEKEQMVDLQNTPKNFLFALDSVGISNVKHPVNVETPEGVQSTVATFELTT
SLVQDRKGINMSRLTEQLDAYHQQGWTVSNRSLIEFAQELAERMEQTEGQLTIRYPWFFTRKAPATGLSGLMNADVMHRV
TYNLETGVANVTVGLVINVTTLCPCSKEISEYSAHNQRGYITIEAGLDETSMDGFDWRAALLDAAESNASAPLHPVLKRP
DEKRATEIAYENPRFVEDMVRLIAADLYEMKQVVNFFVECRNEESIHQHDAIASITFDKRQDA
>Mature_302_residues
STSHVALPTKAERHKLFGSVPPIKGTKPTEKEQMVDLQNTPKNFLFALDSVGISNVKHPVNVETPEGVQSTVATFELTTS
LVQDRKGINMSRLTEQLDAYHQQGWTVSNRSLIEFAQELAERMEQTEGQLTIRYPWFFTRKAPATGLSGLMNADVMHRVT
YNLETGVANVTVGLVINVTTLCPCSKEISEYSAHNQRGYITIEAGLDETSMDGFDWRAALLDAAESNASAPLHPVLKRPD
EKRATEIAYENPRFVEDMVRLIAADLYEMKQVVNFFVECRNEESIHQHDAIASITFDKRQDA

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCH4_EXISA (C4KZ55)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002885813.1
- ProteinModelPortal:   C4KZ55
- GeneID:   7869435
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_1441
- OMA:   SLMDYEV
- ProtClustDB:   PRK13674
- HAMAP:   MF_01527_B
- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042
- Gene3D:   G3DSA:3.10.270.10
- TIGRFAMs:   TIGR00294

Pfam domain/function: PF02649 DUF198

EC number: =3.5.4.16

Molecular weight: Translated: 33960; Mature: 33828

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSHVALPTKAERHKLFGSVPPIKGTKPTEKEQMVDLQNTPKNFLFALDSVGISNVKHP
CCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCHHHHEEHHHCCCCCCCCC
VNVETPEGVQSTVATFELTTSLVQDRKGINMSRLTEQLDAYHQQGWTVSNRSLIEFAQEL
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AERMEQTEGQLTIRYPWFFTRKAPATGLSGLMNADVMHRVTYNLETGVANVTVGLVINVT
HHHHHHCCCCEEEEECEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHEEEEEEEEEH
TLCPCSKEISEYSAHNQRGYITIEAGLDETSMDGFDWRAALLDAAESNASAPLHPVLKRP
HCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCC
DEKRATEIAYENPRFVEDMVRLIAADLYEMKQVVNFFVECRNEESIHQHDAIASITFDKR
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEEECCCC
QDA
CCC
>Mature Secondary Structure 
STSHVALPTKAERHKLFGSVPPIKGTKPTEKEQMVDLQNTPKNFLFALDSVGISNVKHP
CCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCHHHHEEHHHCCCCCCCCC
VNVETPEGVQSTVATFELTTSLVQDRKGINMSRLTEQLDAYHQQGWTVSNRSLIEFAQEL
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AERMEQTEGQLTIRYPWFFTRKAPATGLSGLMNADVMHRVTYNLETGVANVTVGLVINVT
HHHHHHCCCCEEEEECEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHEEEEEEEEEH
TLCPCSKEISEYSAHNQRGYITIEAGLDETSMDGFDWRAALLDAAESNASAPLHPVLKRP
HCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCC
DEKRATEIAYENPRFVEDMVRLIAADLYEMKQVVNFFVECRNEESIHQHDAIASITFDKR
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEEECCCC
QDA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA