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The map label for this gene is mtnB

Identifier: 229917164

GI number: 229917164

Start: 1406424

End: 1407041

Strand: Direct

Name: mtnB

Synonym: EAT1b_1438

Alternate gene names: 229917164

Gene position: 1406424-1407041 (Clockwise)

Preceding gene: 229917163

Following gene: 229917165

Centisome position: 46.88

GC content: 53.24

Gene sequence:

>618_bases
ATGACCGTACAAGAACGATGGGTCGAACTTGCCGACATTAAAGACGAGCTCGCCGCACGAGATTGGTTCCCCGGGACGAG
TGGCAACCTGGCGATCCGCGTATCGGACGACCCGTTGACGTTCCTCGTGACGGCAAGCGGTCGTGATAAACGAAAGCGTA
CCAATGAAGACTTCGTCCTCGTCGATGCGACCGGTCAATTGATTGGAGAACAGTCAGGCAAACCGTCCGCGGAAACGTTG
CTACACGTCGAAATCTTTAACAACACGAACGCAACCTGTTCCCTTCACGTGCATACGGTCGACAATAACGTCATCTCGGA
ACTGTATGCAGCACAAGGCCATGTGACGTTCACAGGTCAAGAAATTATCAAGGCGCTCGGCTATTGGGAAGAGACGGCAA
GTGTCCGGATCCCCATTATCGAAAATCACGCGGATATCCCGACACTCGCTCGCGCGTTCGCCCCACATGTCACAGGCGAT
GCCGGTGCCGTCCTCATCCGGAACCACGGGATCACCGTTTGGGGCGAAACGCCCGCTGCGGCAAAACGTTACTTAGAGGC
ATATGAATTTTTGTTTAGCTATTCATTAAAATTACGCGCCTTAGGCGTCCATTCATAA

Upstream 100 bases:

>100_bases
CACGAGGTCAACTGATTTCGCTTTGTGAGGCGGAAGGAATTCGACATGTTCCGTTCGAGACATTCTATGACATTTCAGCT
TACATGAAAGGAGTGAACGT

Downstream 100 bases:

>100_bases
GGAGGAATTCAACATGGCAACGATTTATTTTCAACAAACCGAAGAACGTGTCAGCGACCAACAAGAGGTACGTGACTTTT
TAGAATCACGAGACATTCTT

Product: methylthioribulose-1-phosphate dehydratase

Products: NA

Alternate protein names: MTRu-1-P dehydratase

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MTVQERWVELADIKDELAARDWFPGTSGNLAIRVSDDPLTFLVTASGRDKRKRTNEDFVLVDATGQLIGEQSGKPSAETL
LHVEIFNNTNATCSLHVHTVDNNVISELYAAQGHVTFTGQEIIKALGYWEETASVRIPIIENHADIPTLARAFAPHVTGD
AGAVLIRNHGITVWGETPAAAKRYLEAYEFLFSYSLKLRALGVHS

Sequences:

>Translated_205_residues
MTVQERWVELADIKDELAARDWFPGTSGNLAIRVSDDPLTFLVTASGRDKRKRTNEDFVLVDATGQLIGEQSGKPSAETL
LHVEIFNNTNATCSLHVHTVDNNVISELYAAQGHVTFTGQEIIKALGYWEETASVRIPIIENHADIPTLARAFAPHVTGD
AGAVLIRNHGITVWGETPAAAKRYLEAYEFLFSYSLKLRALGVHS
>Mature_204_residues
TVQERWVELADIKDELAARDWFPGTSGNLAIRVSDDPLTFLVTASGRDKRKRTNEDFVLVDATGQLIGEQSGKPSAETLL
HVEIFNNTNATCSLHVHTVDNNVISELYAAQGHVTFTGQEIIKALGYWEETASVRIPIIENHADIPTLARAFAPHVTGDA
GAVLIRNHGITVWGETPAAAKRYLEAYEFLFSYSLKLRALGVHS

Specific function: Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. MtnB subfamily

Homologues:

Organism=Homo sapiens, GI166235186, Length=194, Percent_Identity=28.3505154639175, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322484, Length=204, Percent_Identity=30.3921568627451, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNB_EXISA (C4KZ52)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002885810.1
- GeneID:   7869432
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_1438
- OMA:   EFLFECE
- ProtClustDB:   PRK06754
- HAMAP:   MF_01677
- InterPro:   IPR001303
- InterPro:   IPR017714
- Gene3D:   G3DSA:3.40.225.10
- TIGRFAMs:   TIGR03328

Pfam domain/function: PF00596 Aldolase_II; SSF53639 Aldolase_II_N

EC number: =4.2.1.109

Molecular weight: Translated: 22571; Mature: 22439

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQERWVELADIKDELAARDWFPGTSGNLAIRVSDDPLTFLVTASGRDKRKRTNEDFVL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEEECCCCCHHHCCCCCEEE
VDATGQLIGEQSGKPSAETLLHVEIFNNTNATCSLHVHTVDNNVISELYAAQGHVTFTGQ
EEECCCEECCCCCCCCHHEEEEEEEECCCCCEEEEEEEECCCHHHHHHHHHCCCEEECHH
EIIKALGYWEETASVRIPIIENHADIPTLARAFAPHVTGDAGAVLIRNHGITVWGETPAA
HHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCEEEEEECCEEEECCCHHH
AKRYLEAYEFLFSYSLKLRALGVHS
HHHHHHHHHHHHHHCEEEEEEECCC
>Mature Secondary Structure 
TVQERWVELADIKDELAARDWFPGTSGNLAIRVSDDPLTFLVTASGRDKRKRTNEDFVL
CHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEEECCCCCHHHCCCCCEEE
VDATGQLIGEQSGKPSAETLLHVEIFNNTNATCSLHVHTVDNNVISELYAAQGHVTFTGQ
EEECCCEECCCCCCCCHHEEEEEEEECCCCCEEEEEEEECCCHHHHHHHHHCCCEEECHH
EIIKALGYWEETASVRIPIIENHADIPTLARAFAPHVTGDAGAVLIRNHGITVWGETPAA
HHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCEEEEEECCEEEECCCHHH
AKRYLEAYEFLFSYSLKLRALGVHS
HHHHHHHHHHHHHHCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA