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The map label for this gene is atpH

Identifier: 229917038

GI number: 229917038

Start: 1288510

End: 1289043

Strand: Reverse

Name: atpH

Synonym: EAT1b_1312

Alternate gene names: 229917038

Gene position: 1289043-1288510 (Counterclockwise)

Preceding gene: 229917039

Following gene: 229917037

Centisome position: 42.97

GC content: 52.25

Gene sequence:

>534_bases
ATGAACGCATCACTAGCAAAACGCTATGCCAAAGCGCTCTTCGACTTAGCGCGGGAACAAGGCACGCTCGACCAAGTCGA
AGCGGAAGTGCGTCTGCTCGATGAAGTGCTCCACGCGACTCCTGAGCTCATGGATCTCTTAACGAATCCGGCAGTCAGTG
ACAGCGAGCTTGCACAGCTTTTAAAAGACAGCTTTGGTGATATGACGGCGATTGTCGTGAACACACTTCTCGTCATGGTC
GAAAACGACCGTGCGGCAGAGGTTCGCGCATTGCCACGTTACGTCCGCGAATTGATCAACGACTACCGTGGGATTGCAGA
GGGTATTGTCACAAGCGCCTACCCGTTGTCGGCAACAGACTTGAAAGACGTCGAACTCGTCTTCGGACAGAAGCTCGGGA
AGACGCTCCAATTGAAGAACGTCGTCGATGAAGAAGTCATCGGTGGACTCCGTGTCCAAGTCGGATACACGACGTACGAT
GATACGATCGAAACGAAACTTACACGCCTTGAGCGTGAATTGTTGAATGCGTAA

Upstream 100 bases:

>100_bases
CGGCAGCACGCCACGTCCTTCAATCAGACCTTAAAGGCGATGAAGCGAAACAACGTGCCCTCGTCACAGACTTCCTGTCT
AAAGCGAAAGGTGCGAACTG

Downstream 100 bases:

>100_bases
GAAATAGGGGTGAATTCAATGACAATCAAAGCTGAAGAAATCAGCGCCCTGCTAAAAGAACGAATCGCTTCGTACGGTTC
TGAAATCGAAGTCAGCGAGA

Product: ATP synthase F1, delta subunit

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MNASLAKRYAKALFDLAREQGTLDQVEAEVRLLDEVLHATPELMDLLTNPAVSDSELAQLLKDSFGDMTAIVVNTLLVMV
ENDRAAEVRALPRYVRELINDYRGIAEGIVTSAYPLSATDLKDVELVFGQKLGKTLQLKNVVDEEVIGGLRVQVGYTTYD
DTIETKLTRLERELLNA

Sequences:

>Translated_177_residues
MNASLAKRYAKALFDLAREQGTLDQVEAEVRLLDEVLHATPELMDLLTNPAVSDSELAQLLKDSFGDMTAIVVNTLLVMV
ENDRAAEVRALPRYVRELINDYRGIAEGIVTSAYPLSATDLKDVELVFGQKLGKTLQLKNVVDEEVIGGLRVQVGYTTYD
DTIETKLTRLERELLNA
>Mature_177_residues
MNASLAKRYAKALFDLAREQGTLDQVEAEVRLLDEVLHATPELMDLLTNPAVSDSELAQLLKDSFGDMTAIVVNTLLVMV
ENDRAAEVRALPRYVRELINDYRGIAEGIVTSAYPLSATDLKDVELVFGQKLGKTLQLKNVVDEEVIGGLRVQVGYTTYD
DTIETKLTRLERELLNA

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=174, Percent_Identity=28.735632183908, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320504, Length=175, Percent_Identity=31.4285714285714, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_EXISA (C4KYS6)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002885684.1
- GeneID:   7870280
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_1312
- OMA:   AYDEEAG
- ProtClustDB:   CLSK2489914
- HAMAP:   MF_01416
- InterPro:   IPR000711
- InterPro:   IPR020781
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 19668; Mature: 19668

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASLAKRYAKALFDLAREQGTLDQVEAEVRLLDEVLHATPELMDLLTNPAVSDSELAQL
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHH
LKDSFGDMTAIVVNTLLVMVENDRAAEVRALPRYVRELINDYRGIAEGIVTSAYPLSATD
HHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LKDVELVFGQKLGKTLQLKNVVDEEVIGGLRVQVGYTTYDDTIETKLTRLERELLNA
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNASLAKRYAKALFDLAREQGTLDQVEAEVRLLDEVLHATPELMDLLTNPAVSDSELAQL
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHH
LKDSFGDMTAIVVNTLLVMVENDRAAEVRALPRYVRELINDYRGIAEGIVTSAYPLSATD
HHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LKDVELVFGQKLGKTLQLKNVVDEEVIGGLRVQVGYTTYDDTIETKLTRLERELLNA
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA