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The map label for this gene is atpA

Identifier: 229917037

GI number: 229917037

Start: 1286983

End: 1288491

Strand: Reverse

Name: atpA

Synonym: EAT1b_1311

Alternate gene names: 229917037

Gene position: 1288491-1286983 (Counterclockwise)

Preceding gene: 229917038

Following gene: 229917036

Centisome position: 42.95

GC content: 50.36

Gene sequence:

>1509_bases
ATGACAATCAAAGCTGAAGAAATCAGCGCCCTGCTAAAAGAACGAATCGCTTCGTACGGTTCTGAAATCGAAGTCAGCGA
GACAGGTACAGTCATTCAAGTAGGTGACGGTATCGCTCGTGCACACGGACTCGATAACGTTATGGCGGGGGAACTCGTAG
AGTTCTCTAACGGCGTAATGGGCTTGGCGCAAAACTTAGAAGAAGGTAACGTCGGGATTATCATCCTTGGCGATTACAAA
GGTATTAAAGAAGGCGACTCTGTCAAACGTACAGGTCGTATCATGGAAGTTCCAGTTGGTGAGGCACTCCTCGGACGTGT
CGTCAACCCACTCGGACAACCAATCGATGGTCTTGGACCAATCGTAACTGACACGTATAACCCGATTGAGCGTAAAGCTT
ACGGCGTTATGGCACGTAAATCGGTTCACGAACCACTTCAAACAGGAATTAAGGCGATTGACGCCCTCGTTCCAATCGGT
CGTGGTCAGCGTGAGCTCATCATCGGTGACCGTCAGACAGGTAAAACATCTGTTGCCATCGATACGATTATCAACCAAAA
AGAAGAGAACATGATTTGTATCTACGTTGCTATCGGTCAGAAAGAATCGACTGTACGTGGCGTAGTAGAGACGCTTCGTC
AAAACGGAGCGCTCGACTATACAATCGTCGTTTCGGCATCGGCATCACAGCCGGCACCACTTCTTTACCTCGCACCATTC
GCAGGGGTATCGATGGGTGAGTACTTCATGGATCGCGGACAACACGTCCTCGTCGTTTATGATGACCTTTCGAAACAAGC
GGCAGCTTACCGTGAGCTCTCGCTCCTTCTCCGTCGTCCTCCAGGCCGCGAAGCCTACCCAGGGGATGTCTTCTACCTCC
ACTCACGCCTTCTTGAGCGTGCAGCGAAGTTGAACGACGAACTCGGCGGTGGTTCATTGACAGCACTTCCGTTCATCGAG
ACACAAGCATCGGATATCTCAGCATATATCCCGACAAACGTTATCTCGATCACAGACGGTCAGATCTTCCTTCAGTCGGA
CCTCTTCTTCTCTGGGGTACGCCCAGCGATCAACGCAGGTCTCTCGGTATCGCGTGTTGGTGGTTCGGCACAGGTGAAAG
CGATGAAGAAAGTTGCTGGTACACTTCGTCTTGACCTCGCGTCTTACCGTGAGCTCGAAGCGTTCGCTCAGTTCGGATCA
GATCTCGACAAAGCGACACAATCGAAGTTGAACCGTGGTCAGCGTACGGTTGAAGTCTTGAAACAAGACTTGAACGCACC
GCTTTCTGTAGACAAGCAAGTTATCATCATCTACGCACTCACGAAAGGTCATCTCGATGACATCCCAGTCACAGACATCC
GTCGTTTCGAAACAGAAATGAACGCATGGCTCGACCAAAACCGTAAAGACCTCTGCCGTGAAATCCGTCAGACAGGAAAC
CTTCCTTCAGACGAGGCAATGGTCGACGCAATTACGGAATTCAAAAAGACGTTCTCGCCATCGGTTTAA

Upstream 100 bases:

>100_bases
TGTCCAAGTCGGATACACGACGTACGATGATACGATCGAAACGAAACTTACACGCCTTGAGCGTGAATTGTTGAATGCGT
AAGAAATAGGGGTGAATTCA

Downstream 100 bases:

>100_bases
TCCGGTGACGAGCGTCTATTAAGGTGGTGAATCGAAATGGCATCATTACGTGAGATCCAGATGCGGATCACCTCGACCCA
AAGCACGAAGCAAATCACGA

Product: ATP synthase F1, subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MTIKAEEISALLKERIASYGSEIEVSETGTVIQVGDGIARAHGLDNVMAGELVEFSNGVMGLAQNLEEGNVGIIILGDYK
GIKEGDSVKRTGRIMEVPVGEALLGRVVNPLGQPIDGLGPIVTDTYNPIERKAYGVMARKSVHEPLQTGIKAIDALVPIG
RGQRELIIGDRQTGKTSVAIDTIINQKEENMICIYVAIGQKESTVRGVVETLRQNGALDYTIVVSASASQPAPLLYLAPF
AGVSMGEYFMDRGQHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDELGGGSLTALPFIE
TQASDISAYIPTNVISITDGQIFLQSDLFFSGVRPAINAGLSVSRVGGSAQVKAMKKVAGTLRLDLASYRELEAFAQFGS
DLDKATQSKLNRGQRTVEVLKQDLNAPLSVDKQVIIIYALTKGHLDDIPVTDIRRFETEMNAWLDQNRKDLCREIRQTGN
LPSDEAMVDAITEFKKTFSPSV

Sequences:

>Translated_502_residues
MTIKAEEISALLKERIASYGSEIEVSETGTVIQVGDGIARAHGLDNVMAGELVEFSNGVMGLAQNLEEGNVGIIILGDYK
GIKEGDSVKRTGRIMEVPVGEALLGRVVNPLGQPIDGLGPIVTDTYNPIERKAYGVMARKSVHEPLQTGIKAIDALVPIG
RGQRELIIGDRQTGKTSVAIDTIINQKEENMICIYVAIGQKESTVRGVVETLRQNGALDYTIVVSASASQPAPLLYLAPF
AGVSMGEYFMDRGQHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDELGGGSLTALPFIE
TQASDISAYIPTNVISITDGQIFLQSDLFFSGVRPAINAGLSVSRVGGSAQVKAMKKVAGTLRLDLASYRELEAFAQFGS
DLDKATQSKLNRGQRTVEVLKQDLNAPLSVDKQVIIIYALTKGHLDDIPVTDIRRFETEMNAWLDQNRKDLCREIRQTGN
LPSDEAMVDAITEFKKTFSPSV
>Mature_501_residues
TIKAEEISALLKERIASYGSEIEVSETGTVIQVGDGIARAHGLDNVMAGELVEFSNGVMGLAQNLEEGNVGIIILGDYKG
IKEGDSVKRTGRIMEVPVGEALLGRVVNPLGQPIDGLGPIVTDTYNPIERKAYGVMARKSVHEPLQTGIKAIDALVPIGR
GQRELIIGDRQTGKTSVAIDTIINQKEENMICIYVAIGQKESTVRGVVETLRQNGALDYTIVVSASASQPAPLLYLAPFA
GVSMGEYFMDRGQHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDELGGGSLTALPFIET
QASDISAYIPTNVISITDGQIFLQSDLFFSGVRPAINAGLSVSRVGGSAQVKAMKKVAGTLRLDLASYRELEAFAQFGSD
LDKATQSKLNRGQRTVEVLKQDLNAPLSVDKQVIIIYALTKGHLDDIPVTDIRRFETEMNAWLDQNRKDLCREIRQTGNL
PSDEAMVDAITEFKKTFSPSV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=502, Percent_Identity=60.9561752988048, Blast_Score=612, Evalue=1e-175,
Organism=Homo sapiens, GI4757810, Length=502, Percent_Identity=60.9561752988048, Blast_Score=612, Evalue=1e-175,
Organism=Homo sapiens, GI19913428, Length=306, Percent_Identity=31.0457516339869, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI19913426, Length=308, Percent_Identity=30.5194805194805, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI32189394, Length=372, Percent_Identity=27.1505376344086, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI19913424, Length=252, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1790172, Length=490, Percent_Identity=56.3265306122449, Blast_Score=565, Evalue=1e-162,
Organism=Escherichia coli, GI1788251, Length=330, Percent_Identity=32.1212121212121, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1790170, Length=318, Percent_Identity=27.6729559748428, Blast_Score=109, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71988063, Length=504, Percent_Identity=60.1190476190476, Blast_Score=617, Evalue=1e-177,
Organism=Caenorhabditis elegans, GI71988080, Length=504, Percent_Identity=60.1190476190476, Blast_Score=617, Evalue=1e-177,
Organism=Caenorhabditis elegans, GI71988074, Length=504, Percent_Identity=55.7539682539683, Blast_Score=560, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI17510931, Length=445, Percent_Identity=25.8426966292135, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=298, Percent_Identity=28.8590604026846, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=412, Percent_Identity=25, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17509265, Length=51, Percent_Identity=60.7843137254902, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71988068, Length=74, Percent_Identity=47.2972972972973, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319370, Length=502, Percent_Identity=60.1593625498008, Blast_Score=610, Evalue=1e-175,
Organism=Saccharomyces cerevisiae, GI6319603, Length=305, Percent_Identity=30.8196721311475, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6322581, Length=412, Percent_Identity=26.9417475728155, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24658560, Length=507, Percent_Identity=59.1715976331361, Blast_Score=604, Evalue=1e-173,
Organism=Drosophila melanogaster, GI281361666, Length=301, Percent_Identity=29.2358803986711, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24646341, Length=301, Percent_Identity=29.2358803986711, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17136796, Length=301, Percent_Identity=29.2358803986711, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24638766, Length=316, Percent_Identity=27.2151898734177, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28574560, Length=416, Percent_Identity=25.9615384615385, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI20129479, Length=253, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24583992, Length=257, Percent_Identity=25.6809338521401, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24583988, Length=257, Percent_Identity=25.6809338521401, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24583986, Length=257, Percent_Identity=25.6809338521401, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24583984, Length=257, Percent_Identity=25.6809338521401, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_EXISA (C4KYS5)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002885683.1
- GeneID:   7870279
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_1311
- OMA:   EMALTLW
- ProtClustDB:   CLSK2489913
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54566; Mature: 54435

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKAEEISALLKERIASYGSEIEVSETGTVIQVGDGIARAHGLDNVMAGELVEFSNGVM
CCCCHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCHHHHCCCCHHHHHHHHHHCCCHH
GLAQNLEEGNVGIIILGDYKGIKEGDSVKRTGRIMEVPVGEALLGRVVNPLGQPIDGLGP
HHHHCCCCCCEEEEEEECCCCCCCCCCHHHCCCEEECCCCHHHHHHHHHHHCCCCCCCCC
IVTDTYNPIERKAYGVMARKSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTSVAI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEH
DTIINQKEENMICIYVAIGQKESTVRGVVETLRQNGALDYTIVVSASASQPAPLLYLAPF
HHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCC
AGVSMGEYFMDRGQHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAKLNDELGGGSLTALPFIETQASDISAYIPTNVISITDGQIFLQSDLFFSGVRPAINAG
HHHHCCCCCCCCEEEEEEEECCCCCCEEECCCCEEEEECCEEEEECCCHHHCCCHHHHCC
LSVSRVGGSAQVKAMKKVAGTLRLDLASYRELEAFAQFGSDLDKATQSKLNRGQRTVEVL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHH
KQDLNAPLSVDKQVIIIYALTKGHLDDIPVTDIRRFETEMNAWLDQNRKDLCREIRQTGN
HHHCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
LPSDEAMVDAITEFKKTFSPSV
CCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TIKAEEISALLKERIASYGSEIEVSETGTVIQVGDGIARAHGLDNVMAGELVEFSNGVM
CCCHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCHHHHCCCCHHHHHHHHHHCCCHH
GLAQNLEEGNVGIIILGDYKGIKEGDSVKRTGRIMEVPVGEALLGRVVNPLGQPIDGLGP
HHHHCCCCCCEEEEEEECCCCCCCCCCHHHCCCEEECCCCHHHHHHHHHHHCCCCCCCCC
IVTDTYNPIERKAYGVMARKSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTSVAI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEH
DTIINQKEENMICIYVAIGQKESTVRGVVETLRQNGALDYTIVVSASASQPAPLLYLAPF
HHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCC
AGVSMGEYFMDRGQHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAKLNDELGGGSLTALPFIETQASDISAYIPTNVISITDGQIFLQSDLFFSGVRPAINAG
HHHHCCCCCCCCEEEEEEEECCCCCCEEECCCCEEEEECCEEEEECCCHHHCCCHHHHCC
LSVSRVGGSAQVKAMKKVAGTLRLDLASYRELEAFAQFGSDLDKATQSKLNRGQRTVEVL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHH
KQDLNAPLSVDKQVIIIYALTKGHLDDIPVTDIRRFETEMNAWLDQNRKDLCREIRQTGN
HHHCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
LPSDEAMVDAITEFKKTFSPSV
CCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA